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Showing 1–21 of 21 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: interscalene nerve catheter Clear all
Completed Not applicable Interventional Results available

A Study Comparing Two Methods of Placing an Interscalene Nerve Catheter for Postoperative Pain Control in Patients Who Undergo Open Shoulder Surgery.

NCT01696188
View directory record Official record
Conditions
Shoulder Pain
Interventions
interscalene nerve catheter
Device
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years and older
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 15, 2015 · Synced Sep 24, 2026, 5:48 PM EDT
Terminated Phase 2 Interventional Results available

Exparel Interscalene vs Indwelling Catheter

NCT03827213
View directory record Official record
Conditions
Pain
Interventions
Exparel, Indwelling Interscalene Catheter
Drug · Device
Lead sponsor
Montefiore Medical Center
Other
Eligibility
40 Years to 74 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Mar 6, 2023 · Synced Sep 24, 2026, 5:48 PM EDT
Not listed Not applicable Interventional

Efficacy of Nerve Blockade Performed Prior to Surgical Intervention Versus Following Surgical Intervention

NCT02666118
View directory record Official record
Conditions
Pain, Shoulder Injury
Interventions
Preemptive Interscalene Block - Single Shot, Postoperative Interscalene Block- Single Shot, Preemptive Interscalene Block - Catheter, Postoperative Interscalene Block - Catheter
Procedure
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
10 Years to 21 Years
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2025
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 1, 2024 · Synced Sep 24, 2026, 5:48 PM EDT
Completed No phase listed Observational

Comparison of Pain Relief After Non Stimulating Interscalene Catheter Placement vs Stimulating Catheter Placement in Total Shoulder Arthroplasty.

NCT01122732
View directory record Official record
Conditions
Pain, Shoulder, Arthroplasty
Interventions
Not listed
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 90 Years
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 31, 2016 · Synced Sep 24, 2026, 5:48 PM EDT
Completed No phase listed Observational

Continuous Blockade of the Brachial Plexus

NCT02769429
View directory record Official record
Conditions
Arthroses, Degenerative Disorder, Osteoarthritis
Interventions
Ultrasound-guided CISB, nerve stimulator-guided CCPVB
Device
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 80 Years
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
2
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 24, 2019 · Synced Sep 24, 2026, 5:48 PM EDT
Completed Not applicable Interventional

Interscalene Catheter vs. Interscalene Liposomal Bupivacaine for Arthroscopic Rotator Cuff Repair

NCT04571606
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Single injection peripheral nerve block with liposomal bupivacaine (Exparel), Single injection peripheral nerve block with 0.25% bupivacaine and subsequent peripheral nerve catheter with 0.2% bupivacaine infusion via onQ pain pump
Procedure
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 12, 2021 · Synced Sep 24, 2026, 5:48 PM EDT
Completed Not applicable Interventional

Interscalene Brachial Plexus Block Washout to Reverse Inadvertent Phrenic Nerve Blockade

NCT03677778
View directory record Official record
Conditions
Anesthesia, Local, Phrenic Nerve Paralysis, Upper Extremity Injury, Phrenic Nerve Palsy on the Left, Phrenic Nerve Palsy on the Right
Interventions
Normal saline injected via interscalene nerve catheter, Placebo
Procedure · Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Aug 1, 2022 · Synced Sep 24, 2026, 5:48 PM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Comparison of Interscalene Catheter to Single Injection Interscalene Blocks for Total Shoulder Arthroplasties

NCT05868330
View directory record Official record
Conditions
Post Operative Pain, Anesthesia, Nerve Block, Shoulder Osteoarthritis
Interventions
Interscalene Catheter, Exparel Single Shot Interscalene Block
Procedure
Lead sponsor
Melinda Seering
Other
Eligibility
18 Years to 90 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Nov 9, 2025 · Synced Sep 24, 2026, 5:48 PM EDT
Terminated Phase 4 Interventional

Shoulder Adhesive Capsulitis and Ambulatory Continuous Interscalene Nerve Blocks

NCT00875862
View directory record Official record
Conditions
Adhesive Capsulitis, Post-operative Pain
Interventions
Interscalene catheter with Ropivicaine or normal saline
Procedure
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jul 24, 2019 · Synced Sep 24, 2026, 5:48 PM EDT
Completed Not applicable Interventional

Interscalene Bupivacaine With Either Liposomal Bupivacaine or Continuous Peripheral Nerve Block for Shoulder Arthroscopy

NCT03816982
View directory record Official record
Conditions
Shoulder Pain
Interventions
Single-injection bupivacaine HCl plus liposomal bupivacaine, Single-injection bupivacaine HCl plus a subsequent bupivacaine CISB
Procedure
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Aug 22, 2023 · Synced Sep 24, 2026, 5:48 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Analgesic Efficacy of Interscalene Nerve Block Versus Local Infiltration Analgesia Following Total Shoulder Arthroplasty

NCT02876055
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Single shot interscalene nerve block, Continuous interscalene nerve block, Local Infiltration Analgesia (LIA)
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
125 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 15, 2019 · Synced Sep 24, 2026, 5:48 PM EDT
Completed Not applicable Interventional

Comparison of Pulmonary Function and Efficacy of Different Nerve Block Catheters for Shoulder Surgery

NCT02117778
View directory record Official record
Conditions
Post-Operative Pain
Interventions
Continuous Nerve Block
Procedure
Lead sponsor
Benaroya Research Institute
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 2, 2017 · Synced Sep 24, 2026, 5:48 PM EDT
Completed Phase 4 Interventional

Perineural Catheter Insertion Distance for Continuous Peripheral Nerve Blocks

NCT00997867
View directory record Official record
Conditions
Lower Extremity Surgery, Upper Extremity Surgery, Post-operative Pain
Interventions
Sciatic catheter left 0-1cm past needle tip vs. 5-6cm past needle tip
Procedure
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Oct 27, 2010 · Synced Sep 24, 2026, 5:48 PM EDT
Not listed Not applicable Interventional

Indwelling Interscalene Nerve Catheters in Surgical Management of Idiopathic Adhesive Capsulitis

NCT01606332
View directory record Official record
Conditions
Frozen Shoulder
Interventions
Interscalene block with nerve catheter
Procedure
Lead sponsor
OAD Orthopaedics
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Warrenville, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 10, 2013 · Synced Sep 24, 2026, 5:48 PM EDT
Completed Phase 4 Interventional Results available

Liposomal Bupivacaine Single-Injection Interscalene Block vs. Continuous Interscalene Block for Primary Total Shoulder Arthroplasty

NCT05005260
View directory record Official record
Conditions
Pain, Postoperative, Brachial Plexus Block
Interventions
Bupivacaine HCl, Liposomal bupivacaine + Bupivacaine Hcl 0.5% Inj
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 6, 2024 · Synced Sep 24, 2026, 5:48 PM EDT
Terminated Phase 4 Interventional

Liposomal Bupivacaine Infiltration vs Continuous Perineural Ropivacaine Infusion for Post-operative Pain After Total Shoulder Arthroplasty

NCT02787226
View directory record Official record
Conditions
Postoperative Pain, Shoulder Arthritis
Interventions
Liposomal Bupivacaine Infiltration, Continuous Perineural Ropivicaine Infusion
Drug
Lead sponsor
Eric Shepard
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 8, 2018 · Synced Sep 24, 2026, 5:48 PM EDT
Completed Not applicable Interventional

Erector Spinae Plane Versus Interscalene Blocks for Shoulder Surgery

NCT03807505
View directory record Official record
Conditions
Anesthesia, Local, Phrenic Nerve Paralysis, Upper Extremity Injury, Shoulder Injury
Interventions
Interscalene brachial plexus nerve block, Erector spinae plane block
Procedure
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Mar 4, 2020 · Synced Sep 24, 2026, 5:48 PM EDT
Withdrawn Phase 4 Interventional

Effective Pain Management During Shoulder Replacement Surgery With EXPAREL

NCT03474510
View directory record Official record
Conditions
Pain, Postoperative, Shoulder Osteoarthritis
Interventions
local infiltration of liposomal bupivacaine, continuous infusion of ropivacaine interscalene nerve block
Drug · Other
Lead sponsor
TriHealth Inc.
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 28, 2021 · Synced Sep 24, 2026, 5:48 PM EDT
Withdrawn Phase 4 Interventional

Single Shot Exparel vs Catheters in Lower Extremity Trauma

NCT07221019
View directory record Official record
Conditions
Fracture Dislocation of Ankle Joint, Fracture Leg, Fracture Femur, Fracture Lower Leg, Fracture
Interventions
Bupivacaine, Exparel + Bupivacaine
Drug
Lead sponsor
George Washington University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Sep 23, 2026 · Synced Sep 24, 2026, 5:48 PM EDT
Terminated Not applicable Interventional

Prospective Evaluation of Interscalene Nerve Catheters vs. Single Injection Blocks

NCT01385449
View directory record Official record
Conditions
Pain
Interventions
interscalene catheter, interscalene block
Procedure
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 79 Years
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
2
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Feb 17, 2019 · Synced Sep 24, 2026, 5:48 PM EDT