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Conditions: Prostate Cancer
Interventions: No intervention; Other
Lead sponsor: Bayer; Industry
Eligibility: 55 Years and older · Male only
Enrollment: 3,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Whippany, New Jersey

Conditions: Crisis Intervention, Crisis Response Plan
Interventions: Crisis Intervention - The First Line Leaders (FLL) program will utilize templated guides developed with stakeholders from the Idaho Army National Guard (ARNG), known as the Total Health Action Plan (T; Behavioral
Lead sponsor: University of Rochester; Other
Eligibility: 18 Years and older
Enrollment: 450 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Boise, Idaho

Conditions: Tobacco Cigarette Smoking
Interventions: Smartphone-based intervention messages; Behavioral
Lead sponsor: Johns Hopkins Bloomberg School of Public Health; Other
Eligibility: 18 Years to 30 Years
Enrollment: 160 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Cardiovascular Health
Interventions: Culturally-adapted intervention to improve cardiovascular health in American Indian women; Behavioral
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years to 55 Years · Female only
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: Pembroke, North Carolina

Conditions: Suicidal Ideation and Behavior
Interventions: Facilitated Referral to Crisis Resources, Text Messaging based Safety Planning Intervention; Behavioral
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years to 24 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Chemotherapy-Induced Peripheral Neuropathy, Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
Interventions: Biospecimen Collection, Educational Intervention, Electronic Health Record Review, Interview, Survey Administration; Procedure · Other
Lead sponsor: University of Michigan Rogel Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Clinical Stage II Cutaneous Merkel Cell Carcinoma AJCC v8, Clinical Stage III Cutaneous Merkel Cell Carcinoma AJCC v8, Clinical Stage IV Cutaneous Merkel Cell Carcinoma AJCC v8, Locally Advanced Basal Cell Carcinoma, Locally Advanced Malignant Skin Neoplasm, Locally Advanced Merkel Cell Carcinoma, Locally Advanced Mucosal Melanoma, Locally Advanced Squamous Cell Carcinoma
Interventions: Non-Interventional Study; Other
Lead sponsor: Ohio State University Comprehensive Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Alcohol Drinking
Interventions: Task-based behavioral intervention; Behavioral
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 21 Years to 35 Years
Enrollment: 280 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: New York, New York

Conditions: Autism Spectrum Disorder, Development Delay, Development Disorder, Child, Developmental Disability
Interventions: Center Based or In Home Early Intervention Program; Behavioral
Lead sponsor: Stanford University; Other
Eligibility: 2 Years to 5 Years
Enrollment: 75 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2034
U.S. locations: 1
States / cities: Stanford, California

Conditions: Cardiovascular Risk Factor, Dietary Modification
Interventions: MeLT Dietary intervention, MeLT dietary intervention with TMAO, TLC Dietary intervention; Behavioral
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years and older
Enrollment: 170 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2026
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Anatomic Stage IV Breast Cancer AJCC v8, Glioblastoma, Lung Carcinoma, Malignant Solid Neoplasm, Metastatic Breast Carcinoma
Interventions: Non-Interventional Study; Other
Lead sponsor: City of Hope Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 160 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Duarte, California

Conditions: Acinetobacter Baumannii-calcoaceticus Complex Infection (ABC)
Interventions: Non-interventional; Other
Lead sponsor: Innoviva Specialty Therapeutics; Industry
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 12
States / cities: Sacramento, California • Gainesville, Florida • Tampa, Florida + 9 more

Conditions: Nutritional Intervention, Sleep Deprivation
Interventions: Ketogenic Intervention, Ketone Ester, Mediterranean Intervention, Placebo; Other · Dietary Supplement
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years to 40 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Coronary Artery Stenosis
Interventions: State-of-the-Art Percutaneous Coronary Intervention, standard CABG; Procedure
Lead sponsor: Duk-Woo Park, MD; Other
Eligibility: 20 Years and older
Enrollment: 1,500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2029
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: ASD, Autism, Autism Spectrum Disorder
Interventions: Center-Based Pivotal Response Treatment (PRT) Intervention (PRT-C), Home-Based Pivotal Response Treatment (PRT Intervention (PRT-H); Behavioral
Lead sponsor: Stanford University; Other
Eligibility: 2 Years to 5 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2028
U.S. locations: 1
States / cities: Stanford, California

Conditions: Alcohol Drinking, Opioid Use
Interventions: mHealth Intervention; Behavioral
Lead sponsor: Brown University; Other
Eligibility: 18 Years to 25 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Diabetes Mellitus
Interventions: Enhanced CGM Interventions, Standard of Care; Other
Lead sponsor: Montefiore Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 20,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Lung Non-Small Cell Carcinoma
Interventions: Aerobic Exercise, Biospecimen Collection, Cardiopulmonary Exercise Testing, Dual X-ray Absorptiometry, Educational Intervention, Electronic Health Record Review, Exercise Intervention, Physical Performance Testing, Pulmonary Function Test, Questionnaire Administration; Other · Procedure
Lead sponsor: Fred Hutchinson Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Opioid Use Disorder
Interventions: Acute Stress Intervention (MAST-based), Non-Stress Intervention (NST-based); Behavioral
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older
Enrollment: 125 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
Interventions: Non-Interventional Study; Other
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Jacksonville, Florida

Conditions: Fatigue, Post-Acute COVID-19 Syndrome
Interventions: Attention Control, Dietary intervention to mitigate Post-Acute COVID-19 Syndrome; Other
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 50 Years to 94 Years
Enrollment: 56 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Hiv, Substance Use Disorders
Interventions: Control Condition, Matter Intervention; Behavioral
Lead sponsor: Boston University; Other
Eligibility: 18 Years and older
Enrollment: 256 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 2
States / cities: Miami, Florida • Boston, Massachusetts

Conditions: Dependence, Opioid
Interventions: Brief, values based intervention for early buprenorphine treatment; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Bedford, Massachusetts

Conditions: Irritable Bowel Syndrome
Interventions: Educational Intervention, Positive Psychology (PP) Intervention; Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Boston, Massachusetts

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A Study to Learn About Heart-Related Risks in Elderly Men With Advanced Prostate Cancer Treated With Enzalutamide or Darolutamide

Reducing Crises and Suicide Within the Idaho Army National Guard

Testing the Impact of Smartphone-based Messaging to Support Young Adult Smoking Cessation

Mind Your Heart Intervention for American Indian Women

Design and Feasibility of an SMS-based Safety Planning Intervention

A Virtually Delivered Diet Intervention (LASO-3) for the Improvement of Chemotherapy-Induced Peripheral Neuropathy in Cancer Survivors Post-treatment

Studying Off Label Insurance Coverage for Patients With Cutaneous Cancers a "Filter" Observational Study

Effects of Stereotype Threat on Impulsivity and Its Relation to Alcohol Use in African Americans: An fMRI Study

A Center Based Early Intervention Program For Preschoolers With Developmental Disorders

Gut Flora Metabolite Reduction After Dietary Intervention (GRADY)

Investigating the Feasibility and Acceptability of an Innovative Interdisciplinary Supportive Care Program: Couples Coping Together Against Cancer

A Study to Assess the Safety and Risk of Hypersensitivity Reactions of Sulbactam-durlobactam in Adults With Acinetobacter Baumannii-calcoaceticus (ABC) Complex Infection

Ketone Conferred Resiliency Against Sleep Restriction With Nutritional Intervention.

Diabetes-Centered Evaluation of Revascularization Strategy of Functional and Imaging-CombiNEd State-of-the-Art Percutaneous Coronary Intervention or Coronary-Artery Bypass Grafting in Patients With Diabetes Mellitus and Multivessel Coronary Artery Disease

Trial of Center-Based vs. In-Home Pivotal Response Treatment (PRT) in Autism

Targeting Alcohol-Opioid Co-Use Among Young Adults Using a Novel MHealth Intervention

SPARK-CGM Implementation

Exercise Training for the Improvement of Immune Activity and Treatment Outcomes During Immunotherapy for Non-small Cell Lung Cancer, BOOST Trial

Resilience Among Individuals With Opioid Use Disorder

Using Induced-Pluripotent Stem Cells to Model Cancer Therapy-Related Adverse Events

Dietary Intervention to Mitigate Post-Acute COVID-19 Syndrome

Mitigating the Impact of Stigma and Shame Among People Living With HIV and Substance Use Disorders

A Brief Values Intervention to Support Veterans in Early Buprenorphine Treatment

Well-being in IBS: Strengths and Happiness (WISH) 2.0