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Showing 1537–1560 of 47,841 matching trials from the live ClinicalTrials.gov search.
Completed Not applicable Interventional Accepts healthy volunteers

High Resolution Wavefront-guided vs. Wavefront Optimized LASIK

NCT02565537
Conditions
Nearsightedness, Astigmatism
Interventions
LASIK
Procedure
Lead sponsor
Stanford University
Other
Eligibility
21 Years to 60 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2025
U.S. locations
1
States / cities
Palo Alto, California
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Comparison of Medical and Surgical Treatment of Uncomplicated Acute Appendicitis in Children

NCT02991937
Conditions
Appendicitis
Interventions
Piperacillin/Tazobactam, Surgical Treatment
Drug · Procedure
Lead sponsor
NYU Langone Health
Other
Eligibility
6 Years to 17 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
New York, New York
Conditions
Colorectal Cancer
Interventions
Irinotecan, CyberKnife
Drug · Radiation
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Park Ridge, Illinois
Conditions
Retinoblastoma, Retinal Neoplasm
Interventions
Enucleation, Vincristine, Carboplatin, Focal Therapies, External Beam Radiation, Vincristine and Topotecan, Vincristine + Carboplatin + Etoposide, vincristine, cyclophosphamide, and doxorubicin, Vincristine, Carboplatin and Etoposide, Periocular carboplatin, G-CSF
Procedure · Drug · Radiation + 1 more
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
Not listed
Enrollment
107 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2024
U.S. locations
1
States / cities
Memphis, Tennessee
Conditions
Cancer
Interventions
Communicating About Sexual Concerns and Dysfunction Effectively
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Durham, North Carolina
Completed Not applicable Interventional Accepts healthy volunteers

Latinos CARES (Colorectal Cancer Awareness, Research, Education and Screening)

NCT03078361
Conditions
Colorectal Cancer, Colorectal Carcinoma
Interventions
Immunochemical Fecal Occult Blood Test (I-FOBT) Kit, LATINOS CARES Toolkit, Standard Intervention
Other · Behavioral
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
50 Years to 70 Years
Enrollment
159 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2022
U.S. locations
1
States / cities
Tampa, Florida
Terminated Not applicable Interventional Results available

Enhanced Bioscaffold for Volumetric Muscle Loss

NCT04051242
Conditions
Muscle Loss
Interventions
XenMatrix™ AB Surgical Graft
Device
Lead sponsor
J. Peter Rubin, MD
Other
Eligibility
18 Years to 70 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Cervical Degenerative Disc Disease, Degenerative Spondylolisthesis, Spinal Stenosis
Interventions
NeoFuse, Allograft
Biological · Procedure
Lead sponsor
Mesoblast, Ltd.
Industry
Eligibility
18 Years to 70 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
8
States / cities
Sacramento, California • Santa Monica, California • Denver, Colorado + 5 more
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

Inpatient Stroke Recovery Using Sensors

NCT04219670
Conditions
Stroke
Interventions
Wearable sensors
Diagnostic Test
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Colitis, Ulcerative, Obesity
Interventions
Phentermine-Topiramate, Placebo
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
La Jolla, California
Conditions
Menopause
Interventions
Hormone Replacement Therapy
Drug
Lead sponsor
National Center for Research Resources (NCRR)
NIH
Eligibility
45 Years to 55 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
1
States / cities
Burlington, Vermont
Completed Not applicable Interventional Accepts healthy volunteers

Family-based Approach to Promotion of Health - FAMILIA (Project 1)

NCT02343341
Conditions
Promoting Cardiovascular Health in Younger Age Group
Interventions
Preschool Health Promotion Education Program
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
3 Years to 5 Years
Enrollment
562 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
15
States / cities
New York, New York
Recruiting Not applicable Interventional Accepts healthy volunteers

Web-based Program to Improve Self-management Among Veterans-caregiver Dyads

NCT06001541
Conditions
Chronic Medical Conditions
Interventions
Web-SUCCEED
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
396 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
1
States / cities
Palo Alto, California
Conditions
Cancer Diagnosis, Non-Metastatic Neoplasm, Anxiety, Anxiety Disorders, Depression, Depressive Disorder, Depression, Anxiety, Desmoid
Interventions
Promoting Resilience in Stress Management Program
Behavioral
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years to 39 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Brighton, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers

Physical Therapists Identifying Patients With Opioid Misuse

NCT05497154
Conditions
Opioid Misuse, Musculoskeletal Pain
Interventions
Training Arm
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Salt Lake City, Utah
Conditions
Hysterectomy
Interventions
IV N-acetylcysteine, IV Placebo
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Charleston, South Carolina
Completed Not applicable Interventional Accepts healthy volunteers

Authentic Connections for Nurse Leaders

NCT03616756
Conditions
Stress
Interventions
Authentic Connections, Protected time
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
3
States / cities
Scottsdale, Arizona • Jacksonville, Florida • Rochester, Minnesota
Conditions
Hypertension, Type 2 Diabetes Mellitus (T2DM)
Interventions
Coach-Directed Tailored DASH Groceries Plus Lifestyle Intervention, Self-Shopping DASH diet advice
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Completed Not applicable Interventional

Brief Shame Intervention Study

NCT03463356
Conditions
Shame, Social Anxiety Disorder
Interventions
Shame Intervention
Behavioral
Lead sponsor
Miami University
Other
Eligibility
18 Years to 100 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Oxford, Ohio
Conditions
Anesthesia, Dental
Interventions
Phentolamine Mesylate (NV-101)
Drug
Lead sponsor
Novalar Pharmaceuticals, Inc.
Industry
Eligibility
4 Years to 11 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Diabetic Foot Ulcers, Diabetes
Interventions
Topical wound dressing, Human Amnion Allograft, usual wound care
Device · Biological · Other
Lead sponsor
University of North Dakota
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Grand Forks, North Dakota
Completed Not applicable Interventional Accepts healthy volunteers

Safety and Efficacy of a Probiotic Supplement

NCT05425329
Conditions
Gastrointestinal Discomfort
Interventions
I3.1, Placebo treatment
Dietary Supplement
Lead sponsor
University of Memphis
Other
Eligibility
20 Years to 50 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Memphis, Tennessee
Conditions
Acute Myelogenous Leukemia, Myelodysplastic Syndrome, Chronic Lymphocytic Leukemia
Interventions
Mylotarg, Fludarabine, Melphalan, Anti-thymocyte globulin, Stem cell transplant
Drug · Procedure
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
12 Years to 75 Years
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2006
U.S. locations
1
States / cities
Houston, Texas
Completed Not applicable Interventional Accepts healthy volunteers Results available

Early Intervention to Promote Cardiovascular Health of Mothers and Children (ENRICH) During Pregnancy

NCT05822531
Conditions
Cardiovascular Diseases, Pregnancy Related, Sedentary Behavior
Interventions
Maternal CVH Intervention
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
18 Years and older · Female only
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
2
States / cities
Altoona, Pennsylvania • Danville, Pennsylvania