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ClinicalTrials.gov public records Last synced Oct 2, 2026, 2:55 PM EDT

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Showing 1–3 of 3 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: l-tetrahydropalmatine (l-THP) Clear all
Completed Phase 1 Interventional

Pharmacokinetic and Safety Evaluation of L-tetrahydropalmatine (l-THP) With Cocaine Exposure in People With a History of Cocaine Use

NCT01631383
View directory record Official record
Conditions
Cocaine Use
Interventions
l-THP (l-tetrahydropalmatine), Placebo
Drug
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 50 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Catonsville, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 27, 2019 · Synced Oct 2, 2026, 2:55 PM EDT
Completed Not applicable Interventional Results available

Treatment of Schizophrenia With L-tetrahydropalmatine (l-THP): a Novel Dopamine Antagonist With Anti-inflammatory and Antiprotozoal Activity

NCT02118610
View directory record Official record
Conditions
Schizophrenia
Interventions
L-tetrahydropalmatine (30mg), Sugar pill
Drug
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 64 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Catonsville, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 6, 2022 · Synced Oct 2, 2026, 2:55 PM EDT
Withdrawn Phase 2 Interventional

L-tetrahydropalmatine (l-THP) Treatment for Cocaine Use Disorder

NCT02139761
View directory record Official record
Conditions
Cocaine Use
Interventions
l-tetrahydropalmatine (l-THP), Placebo
Drug
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 50 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Catonsville, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 4, 2019 · Synced Oct 2, 2026, 2:55 PM EDT