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ClinicalTrials.gov public records Last synced Oct 14, 2026, 7:39 AM EDT

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Showing 481–504 of 964 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: lidocaine hydrochloride Clear all
Completed Phase 4 Interventional Results available

CESI With Low Dose Lidocaine and Transient Weakness

NCT03127137
View directory record Official record
Conditions
Cervical Radiculitis, Pain
Interventions
Experimental Group 1 triamcinolone and lidocaine, Experimental Group 2 triamcinolone and saline
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
123 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 10, 2023 · Synced Oct 14, 2026, 7:39 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Jet Injection of 1% Buffered Lidocaine Versus Topical ELA-Max for Anesthesia Prior to Intravenous (IV) Catheterization in Children

NCT00444756
View directory record Official record
Conditions
Pain
Interventions
J-tip jet injection of 1% buffered lidocaine
Procedure
Lead sponsor
Norton Healthcare
Other
Eligibility
8 Years to 15 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2006
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Mar 8, 2007 · Synced Oct 14, 2026, 7:39 AM EDT
Completed Phase 2 Interventional Results available

Efficacy of Guanfacine and Lidocaine Combination in Trigeminal Nerve Block for Pain Management in Trigeminal Neuropathy

NCT03865940
View directory record Official record
Conditions
Trigeminal Neuralgia
Interventions
Lidocaine, Guanfacine
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 30, 2025 · Synced Oct 14, 2026, 7:39 AM EDT
Completed Phase 2 Interventional Results available

Buffered Lidocaine for Loop Electrosurgical Excision Procedures (LEEPs)

NCT01405768
View directory record Official record
Conditions
Uterine Cervical Dysplasia
Interventions
sodium bicarbonate buffered lidocaine, Non-buffered lidocaine
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older · Female only
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 28, 2014 · Synced Oct 14, 2026, 7:39 AM EDT
Not listed Not applicable Interventional

Comparison of Prescription Lidocaine Patch to Over the Counter Lidocaine Patch and Placebo for Back Pain and Arthritis

NCT02749123
View directory record Official record
Conditions
Back Pain, Arthritis
Interventions
lidocaine 5% patch, lidocaine 3.6%, menthol 1.25%, Placebo
Drug
Lead sponsor
J.A.R. Laboratories
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
Barrington, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 22, 2016 · Synced Oct 14, 2026, 7:39 AM EDT
Completed Not applicable Interventional Results available

IV Lidocaine on Postoperative Pain and QOR on Morbid Obese Patients Undergoing Bypass Surgery

NCT01180660
View directory record Official record
Conditions
Pain, Obesity
Interventions
Lidocaine Infusion, Normal Saline
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 70 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 7, 2014 · Synced Oct 14, 2026, 7:39 AM EDT
Completed Phase 4 Interventional

Impact of Topical Pharyngeal Anesthetics on Discharge of the Patients When Used in Conjunction With Propofol Sedation in Routine EGD's

NCT02507440
View directory record Official record
Conditions
Topical Anesthesia
Interventions
Lidocaine, Placebo, Propofol
Drug
Lead sponsor
Bassett Healthcare
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Cooperstown, New York
Source: ClinicalTrials.gov public record
Updated Jan 10, 2017 · Synced Oct 14, 2026, 7:39 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Outcomes of Neuraxial Anesthetic Technique on the Trial of Labor After Cesarean (TOLAC)

NCT02105558
View directory record Official record
Conditions
Labor Pain, Complications; Cesarean Section, Pregnancy
Interventions
Epidural anesthesia, Combined spinal and epidural anesthesia
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 19, 2018 · Synced Oct 14, 2026, 7:39 AM EDT
Active, not recruiting Phase 2 Interventional

Intralesional Gardasil-9 for the Treatment of Recalcitrant Warts

NCT07806617
View directory record Official record
Conditions
Warts, Verruca (Warts), Verruca Vulgaris
Interventions
9-valent human papillomavirus vaccine, Sterile Saline
Biological · Other
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Oct 14, 2026, 7:39 AM EDT
Recruiting Phase 4 Interventional

Cryo Rib Fracture Study

NCT06347874
View directory record Official record
Conditions
Rib Fractures
Interventions
Cryoablation, ESP Catheter
Drug
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Oct 14, 2026, 7:39 AM EDT
Completed Phase 4 Interventional Results available

Liposomal Bupivacaine Versus Lidocaine for Skin Graft Donor Site Pain

NCT03854344
View directory record Official record
Conditions
Pain, Postoperative, Burns
Interventions
Lidocaine Hydrochloride, Liposomal bupivacaine, Bupivacaine Hydrochloride
Drug
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Oct 14, 2026, 7:39 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

PENG Block for Arthroscopic Hip Surgery

NCT04508504
View directory record Official record
Conditions
Postoperative Pain, Hip Arthroscopy
Interventions
Preop PENG block, Placebo block, Ropivacaine 0.5% Injectable Solution, Normal Saline
Procedure · Drug
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 25, 2022 · Synced Oct 14, 2026, 7:39 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Trial of 2% Lidocaine Gel for Intrauterine Device (IUD) Insertion

NCT01292447
View directory record Official record
Conditions
Pain
Interventions
2% lidocaine gel, Placebo gel
Drug
Lead sponsor
Women and Infants Hospital of Rhode Island
Other
Eligibility
18 Years to 49 Years · Female only
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
2
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Sep 2, 2020 · Synced Oct 14, 2026, 7:39 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Evaluation of the Depth and Duration of Anesthesia From Heated Lidocaine/Tetracaine (Synera®) Patches Compared With 5% Lidocaine (Lidoderm®) Patches Applied to Healthy Adult Volunteers

NCT01688518
View directory record Official record
Conditions
Healthy
Interventions
Heated Lidocaine/Tetracaine Patch, 5% Lidocaine Patch
Drug
Lead sponsor
CRI Lifetree
Other
Eligibility
18 Years to 60 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jan 4, 2013 · Synced Oct 14, 2026, 7:39 AM EDT
Not listed Phase 4 Interventional

IAL vs PS for Anterior Shoulder Dislocations

NCT03625076
View directory record Official record
Conditions
Shoulder Dislocation
Interventions
Intra-articular Lidocaine, Procedural Sedation with etomidate or propofol
Drug
Lead sponsor
Kendall Healthcare Group, Ltd.
Industry
Eligibility
18 Years to 70 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Aug 13, 2019 · Synced Oct 14, 2026, 7:39 AM EDT
Withdrawn Phase 4 Interventional

The Efficacy of Brisement Compared to Physical Therapy for the Treatment of Achilles Tendinosis

NCT03363789
View directory record Official record
Conditions
Achilles Tendinopathy
Interventions
Brisement injection, Physical Therapy
Biological · Procedure
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 18, 2019 · Synced Oct 14, 2026, 7:39 AM EDT
Completed Phase 2 Interventional

Study Evaluating Heated Lidocaine/Tetracaine Patch in Patients With Pain Associated With Myofascial Trigger Points

NCT01106989
View directory record Official record
Conditions
Myofascial Pain Syndromes
Interventions
Heated lidocaine/tetracaine patch
Drug
Lead sponsor
ZARS Pharma Inc.
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 16, 2012 · Synced Oct 14, 2026, 7:39 AM EDT
Not listed Phase 4 Interventional

Oral vs Intravesical Analgesia for Office Bladder Botox Injections

NCT03755089
View directory record Official record
Conditions
Overactive Bladder Syndrome, Urge Incontinence, Urinary Incontinence, Detrusor Hyperreflexia, Detrusor Instability
Interventions
Phenazopyridine, Lidocaine 2% Injectable Solution
Drug
Lead sponsor
Women and Infants Hospital of Rhode Island
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated May 29, 2020 · Synced Oct 14, 2026, 7:39 AM EDT
Recruiting Phase 4 Interventional

Comparison of Intubation Conditions During Rapid Sequence Induction Obtained With Modified Time Principal Induction With a Standard Intubation Dose of Rocuronium Versus Succinylcholine

NCT06029049
View directory record Official record
Conditions
Anesthesia
Interventions
Modified Time Principle Induction (MTPI) with rocuronium, RSI succinylcholine
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
152 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 10, 2024 · Synced Oct 14, 2026, 7:39 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Needlefree Lidocaine Application for Vulvar Biopsies

NCT07793552
View directory record Official record
Conditions
Vulvar Cancers, Vulva Neoplasm, Vulvar Dysplasia
Interventions
J-Tip, Lidocaine HCl 1%
Device · Drug
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
106 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 28, 2026 · Synced Oct 14, 2026, 7:39 AM EDT
Not yet recruiting Phase 4 Interventional

A Randomized, Placebo-controlled Trial of Nitrous Oxide During In-office Bladder Botox Injections

NCT07387315
View directory record Official record
Conditions
Overactive Bladder, Neurogenic Bladder, Urge Incontinence, Pain, Urinary Incontinence, Urinary Bladder, Overactive, Urinary Bladder, Neurogenic, Urinary Bladder Neurogenesis, Urinary Incontinence, Urge, Pelvic Floor Disorders
Interventions
Pro-Nox Nitrous Oxide/Oxygen Delivery System, Standard Care for Bladder Botox Injection, Sham Mask
Drug · Other
Lead sponsor
TriHealth Inc.
Other
Eligibility
18 Years and older · Female only
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
2
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced Oct 14, 2026, 7:39 AM EDT
Terminated Not applicable Interventional Results available

Acupuncture in Reducing the Severity of Chemoradiation-induced Mucositis in Patients With Oropharyngeal Cancer

NCT01883908
View directory record Official record
Conditions
Mucositis, Oropharyngeal Cancer
Interventions
Acupuncture with Seirin® needles, Usual medical care
Device · Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 7, 2019 · Synced Oct 14, 2026, 7:39 AM EDT
Active, not recruiting Not applicable Interventional

Radiofrequency Ablation After Total Knee Arthroplasty

NCT05473663
View directory record Official record
Conditions
Chronic Knee Pain
Interventions
Radiofrequency Ablation, Sham
Device
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Oct 14, 2026, 7:39 AM EDT
Completed Phase 2 Interventional Results available

Self Hypnotic Relaxation As An Adjunct To Local Anesthesia During Large Core Breast Biopsy

NCT00122369
View directory record Official record
Conditions
Breast Cancer, Anxiety, Pain
Interventions
Self-hypnotic Relaxation, Empathic Attention
Behavioral
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2004
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 28, 2013 · Synced Oct 14, 2026, 7:39 AM EDT