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ClinicalTrials.gov public records Last synced Oct 10, 2026, 6:42 PM EDT

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Showing 145–168 of 530 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: low fat diet Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Glycemic Load, Metabolism & Obesity in Pregnancy

NCT01287299
View directory record Official record
Conditions
Obesity, Insulin Resistance
Interventions
Low Glycemic Load diet, Low Fat Diet
Other
Lead sponsor
UCSF Benioff Children's Hospital Oakland
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2009
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Nov 24, 2020 · Synced Oct 10, 2026, 6:42 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Low Fat Versus Protein Sparing Diet for Weight Loss & Impact on Biomarkers Associated With Breast Cancer Risk

NCT01559194
View directory record Official record
Conditions
Breast Cancer, Weight Loss
Interventions
Low Fat Diet plus exercise, Low Carbohydrate diet + Exercise
Behavioral
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
30 Years and older · Female only
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 14, 2014 · Synced Oct 10, 2026, 6:42 PM EDT
Completed Not applicable Interventional

Effect of Dietary Macronutrient Composition

NCT01371396
View directory record Official record
Conditions
Metabolic Syndrome, Non-alcoholic Fatty Liver Disease, Obesity
Interventions
Low-fat diet, Low-carbohydrate diet
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
20 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Feb 6, 2019 · Synced Oct 10, 2026, 6:42 PM EDT
Terminated Not applicable Interventional

A Nutritional Intervention in Police Officers

NCT02651480
View directory record Official record
Conditions
Overweight, Blood Pressure, Diabetes Mellitus, Type 2
Interventions
Plant-based diet, Control Group
Dietary Supplement
Lead sponsor
Physicians Committee for Responsible Medicine
Other
Eligibility
18 Years to 90 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2026
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Sep 17, 2026 · Synced Oct 10, 2026, 6:42 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Effect of Low-Fat Food on Pexidartinib Pharmacokinetics in Healthy Volunteers

NCT03901313
View directory record Official record
Conditions
Healthy Volunteers
Interventions
Treatment A - 400 mg Fasting, Treatment B - 400 mg Fed, Treatment C - 200 mg Fed
Drug
Lead sponsor
Daiichi Sankyo
Industry
Eligibility
18 Years to 60 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated May 11, 2020 · Synced Oct 10, 2026, 6:42 PM EDT
Recruiting Phase 2 Interventional

FIM+DASH: Food is Medicine Intervention to Promote Healthy Eating and Blood Pressure Control

NCT07332741
View directory record Official record
Conditions
Hypertension, Hypertension (HTN), Obesity & Overweight
Interventions
FIM intervention arm, FIM Usual Care Arm
Combination Product
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
Not listed
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
4
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 10, 2026 · Synced Oct 10, 2026, 6:42 PM EDT
Completed Not applicable Interventional Results available

Adaptation of a Digital Weight Loss Intervention Promoting Self-regulation for Use in Type 2 Diabetes

NCT03650088
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, Overweight and Obesity
Interventions
Behavioral weight loss with digital tools
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 65 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 13, 2023 · Synced Oct 10, 2026, 6:42 PM EDT
Recruiting Not applicable Interventional

Metabolic Impact and Compliance of Controlled, Varying, Mediterranean Diets in Pre-Surgical Prostate Cancer Populations (PROVISIONS)

NCT06487507
View directory record Official record
Conditions
Prostate Cancer
Interventions
Low fat diet, Lower carbohydrate diet
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 80 Years · Male only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Oct 10, 2026, 6:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Worksite Nutrition Study

NCT00481897
View directory record Official record
Conditions
Overweight, Type 2 Diabetes
Interventions
low-fat, vegan diet
Behavioral
Lead sponsor
Physicians Committee for Responsible Medicine
Other
Eligibility
18 Years and older
Enrollment
113 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Aug 7, 2012 · Synced Oct 10, 2026, 6:42 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effects of Watermelon or Low-fat Cookie Consumption on Wellness

NCT06323070
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Low-fat cookies, Watermelon
Other
Lead sponsor
San Diego State University
Other
Eligibility
18 Years to 50 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 28, 2026 · Synced Oct 10, 2026, 6:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Dietary Flavonoids on Intestinal Microbiota, Intestinal Inflammation and Metabolic Syndrome

NCT02728570
View directory record Official record
Conditions
Metabolic Syndrome X, Inflammation
Interventions
High Dietary Flavonoids, Low Dietary Flavonoids
Other
Lead sponsor
Utah State University
Other
Eligibility
18 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Logan, Utah
Source: ClinicalTrials.gov public record
Updated Apr 15, 2016 · Synced Oct 10, 2026, 6:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Trial to Assess Full-fat or Low-fat Dairy Foods on Insulin Sensitivity, RBC FA's and Other Markers of Metabolic Health

NCT04999462
View directory record Official record
Conditions
Overweight and Obesity, Elevated Triglycerides
Interventions
Full-fat fermented dairy, Low-fat fermented dairy, Non-dairy, non-fermented foods
Other
Lead sponsor
Midwest Center for Metabolic and Cardiovascular Research
Other
Eligibility
18 Years to 74 Years
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
4
States / cities
Miami Gardens, Florida • Chicago, Illinois • Gurnee, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Oct 10, 2026, 6:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Colorectal Inflammatory Response to a Western-Style Diet

NCT00932308
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Western-style diet (WD), Prudent Diet (PD)
Dietary Supplement
Lead sponsor
Rockefeller University
Other
Eligibility
50 Years to 72 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 17, 2012 · Synced Oct 10, 2026, 6:42 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

A Study of the Effect Efavirenz on the Plasma Levels of MK-7602 in Healthy Participants (MK-7602-005)

NCT06797674
View directory record Official record
Conditions
Healthy
Interventions
MK-7602, Efavirenz
Drug
Lead sponsor
Merck Sharp & Dohme LLC
Industry
Eligibility
18 Years to 60 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Daytona Beach, Florida
Source: ClinicalTrials.gov public record
Updated Aug 22, 2025 · Synced Oct 10, 2026, 6:42 PM EDT
Not listed Phase 2 Interventional

Ketogenic Diet Treatment of Obesity With Co-morbid Type 2 Diabetes Mellitus and/or Obstructive Sleep Apnea

NCT02069197
View directory record Official record
Conditions
Obesity, Diabetes, Obstructive Sleep Apnea
Interventions
Ketogenic diet, Orlistat, Standardized diet
Other · Drug
Lead sponsor
Mid-Atlantic Epilepsy and Sleep Center, LLC
Other
Eligibility
18 Years to 70 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 17, 2018 · Synced Oct 10, 2026, 6:42 PM EDT
Completed Not applicable Interventional

Low-Carbohydrate Diabetes Prevention Program Among Veterans With Prediabetes

NCT04881890
View directory record Official record
Conditions
PreDiabetes
Interventions
Low-Carbohydrate Diabetes Prevention Program
Behavioral
Lead sponsor
VA Ann Arbor Healthcare System
Federal
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 8, 2022 · Synced Oct 10, 2026, 6:42 PM EDT
Recruiting Not applicable Interventional

Metabolic Impact of Prospective Controlled Mediterranean Type Diets on Prostate Cancer

NCT05590624
View directory record Official record
Conditions
Prostate Cancer
Interventions
Lower-Carbohydrate Med-t-Diet, Low-Fat Med-t-Diet
Other
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
18 Years and older · Male only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 19, 2026 · Synced Oct 10, 2026, 6:42 PM EDT
Completed Phase 3 Interventional

Practice-based Trial of Blood Pressure Control in African Americans

NCT01070056
View directory record Official record
Conditions
Hypertension, Physical Activity, Diet, Medication Adherence
Interventions
Therapeutic Lifestyle Changes (MINT-TLC), Usual Care
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
194 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
4
States / cities
Brooklyn, New York • New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 13, 2013 · Synced Oct 10, 2026, 6:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Prospective Study Investigating the Effects of a Novel Weight Management Program

NCT01875354
View directory record Official record
Conditions
Overweight
Interventions
Dietary Supplements and TR90 Eating Plan, Placebo and Low Fat Eating Plan
Dietary Supplement
Lead sponsor
Pharmanex
Industry
Eligibility
18 Years to 65 Years
Enrollment
141 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Logan, Utah
Source: ClinicalTrials.gov public record
Updated Apr 5, 2017 · Synced Oct 10, 2026, 6:42 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

A Study to Evaluate the Pharmacokinetics (PK), Safety and Tolerability of TAK-788 Followed by Evaluation of the Effects of a Low-Fat Meal on TAK-788 PK and Evaluation of Relative Bioavailability of TAK-788 Capsules in Healthy Participants

NCT03482453
View directory record Official record
Conditions
Healthy Volunteers
Interventions
TAK-788, Placebo
Drug
Lead sponsor
Millennium Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 55 Years
Enrollment
69 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jan 29, 2020 · Synced Oct 10, 2026, 6:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

"ADAPT" The Adaptation to High Fat Diets Extention

NCT00493701
View directory record Official record
Conditions
Healthy
Interventions
High Fat Diet, Low Fat Diet
Behavioral
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
18 Years to 30 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Sep 15, 2022 · Synced Oct 10, 2026, 6:42 PM EDT
Recruiting Not applicable Interventional

Ketogenic and Carnivore (Lion) Diets for Inflammatory Bowel Disease and Rheumatoid Arthritis

NCT07524244
View directory record Official record
Conditions
Rheumatoid Arthritis (RA), Crohn's Disease (CD), Ulcerative Colitis (UC)
Interventions
Ketogenic diet, Carnivore (Lion) Diet
Behavioral
Lead sponsor
Fuller Research Foundation
Other
Eligibility
18 Years to 64 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 5, 2026 · Synced Oct 10, 2026, 6:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Vasoprotective Activities of Low-Fat Milk in Individuals With Metabolic Syndrome

NCT01411293
View directory record Official record
Conditions
Cardiovascular Disease, Metabolic Syndrome, Obesity
Interventions
Low-Fat Milk, Rice Milk
Other
Lead sponsor
University of Connecticut
Other
Eligibility
18 Years to 50 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Storrs, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 6, 2014 · Synced Oct 10, 2026, 6:42 PM EDT
Completed Not applicable Interventional

Can Neural Network Instability in Schizophrenia be Improved With a Very Low Carbohydrate Ketogenic Diet?

NCT05268809
View directory record Official record
Conditions
Schizophrenia, Bipolar Disorder
Interventions
Ketogenic diet
Other
Lead sponsor
Northern California Institute of Research and Education
Other
Eligibility
18 Years to 65 Years
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jan 12, 2026 · Synced Oct 10, 2026, 6:42 PM EDT