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ClinicalTrials.gov public records Last synced Nov 8, 2026, 2:47 PM EST

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Showing 1–24 of 159 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: low sodium diet Clear all

Conditions: Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Interventions: Diet and water adjustment; Behavioral
Lead sponsor: Tufts Medical Center; Other
Eligibility: 18 Years to 60 Years
Enrollment: 34 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Postural Tachycardia Syndrome
Interventions: Cosyntropin administration; Drug
Lead sponsor: Vanderbilt University; Other
Eligibility: 18 Years to 50 Years
Enrollment: 13 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2020
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Hypertension
Interventions: Salt Pills, Placebo Pills; Dietary Supplement
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years to 35 Years
Enrollment: 34 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Orthostatic Hypotension, Falls
Interventions: Medication review, Nutrition/Salt intake, Education, Exercise, Drug Recommendations; Other
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 99 Years
Enrollment: 356 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2016
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Hypertension, Obstructive Sleep Apnea
Interventions: Dietary sodium; Dietary Supplement
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 48 Years to 65 Years
Enrollment: 59 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2020
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Type 2 Diabetes Mellitus
Interventions: Low Glycemic Diet, Control Diet; Other
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 35 Years to 65 Years
Enrollment: 65 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2023
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Hypertension
Interventions: High sodium diet and low sodium diet; Other
Lead sponsor: University of Virginia; Other
Eligibility: 18 Years to 70 Years
Enrollment: 400 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2021
U.S. locations: 1
States / cities: Charlottesville, Virginia

Conditions: Osteoporosis
Interventions: Low Na diet (1.3 g/d), High sodium diet (3.8 g/d); Other
Lead sponsor: Purdue University; Other
Eligibility: 11 Years to 15 Years · Female only
Enrollment: 67 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 1999 – 2000
U.S. locations: 1
States / cities: West Lafayette, Indiana

Conditions: Prehypertension
Interventions: DASH; Other
Lead sponsor: Rockefeller University; Other
Eligibility: 18 Years to 60 Years
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: New York, New York

Conditions: Kidney Stone
Interventions: Breakfast, Spinach smoothie, Kale smoothie, Blended smoothie, V spinach smoothie, Sodium oxalate drink; Dietary Supplement
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years to 70 Years
Enrollment: 82 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2029
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Idiopathic Hypersomnia
Interventions: Low Sodium Oxybate, 24-hour polysomnography, Nextsense EEG earbuds, Axivity device; Drug · Diagnostic Test · Device
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 65 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 4
States / cities: Phoenix, Arizona • Redwood City, California • Jacksonville, Florida + 1 more

Conditions: Idiopathic Nephrotic Syndrome
Interventions: Standard of Care, UrApp; Behavioral
Lead sponsor: Emory University; Other
Eligibility: 18 Years and older
Enrollment: 58 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2025
U.S. locations: 3
States / cities: Atlanta, Georgia • Minneapolis, Minnesota • Portland, Oregon

Conditions: Adult Survivors of Childhood Leukemia
Interventions: individual diet & physical activity counselor and website through Healthways at Hopkins, self directed weight loss, questionnaires, fasting blood draw, measurement of height, weight and waist circumference, and blood pressure; Behavioral · Other
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 358 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2025
U.S. locations: 2
States / cities: New York, New York • Memphis, Tennessee

Conditions: Heart Failure
Interventions: Normal Salt Diet, Cardiac Diet; Other
Lead sponsor: Maya Guglin, MD; Other
Eligibility: 18 Years and older
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: New Brunswick, New Jersey

Conditions: Postural Orthostatic Tachycardia Syndrome
Interventions: Blood Volume, Total Blood Volume, Exercise Capacity Test - Bicycle, Posture Study; Radiation · Procedure
Lead sponsor: Vanderbilt University; Other
Eligibility: 18 Years to 50 Years
Enrollment: 38 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2021
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Hypertension
Interventions: High dietary sodium intake, Low dietary sodium intake; Other
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 52 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: San Diego, California

Conditions: Hypertension
Interventions: DASH diet, Delayed Intervention; Behavioral
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 21 Years to 99 Years
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: End Stage Renal Failure
Interventions: Lower sodium intervention, Progressive Challenge to Post Dialysis Weight; Behavioral · Other
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years to 85 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 2
States / cities: Ann Arbor, Michigan • Livonia, Michigan

Conditions: Development
Interventions: Low Sodium Group; Other
Lead sponsor: Monell Chemical Senses Center; Other
Eligibility: 7 Years to 65 Years
Enrollment: 39 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Hypertension, Hypertension (HTN), Obesity & Overweight
Interventions: FIM intervention arm, FIM Usual Care Arm; Combination Product
Lead sponsor: University of Illinois Chicago; Other
Eligibility: Not listed
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 4
States / cities: Chicago, Illinois

Conditions: Hypertension
Interventions: Intervention group was asked to take their BP daily and rate their motivation level and communicate with the research assistant. Their level will trigger the appropriate behavioral change SMS prompt.; Behavioral
Lead sponsor: University of Nevada, Las Vegas; Other
Eligibility: 18 Years to 29 Years
Enrollment: 29 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Las Vegas, Nevada

Conditions: Healthy Participants
Interventions: Fava beans, Fixed Sodium Diet; Dietary Supplement · Other
Lead sponsor: Vanderbilt University; Other
Eligibility: 18 Years to 60 Years
Enrollment: 14 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2012
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Heart Failure, Heart Failure NYHA Class I, Heart Failure NYHA Class II, Heart Failure NYHA Class III
Interventions: PP-MI Intervention, MI-alone Intervention; Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 280 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2027
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Asthma, Obesity
Interventions: DGA Diet, MCT Diet, KETO Diet; Other
Lead sponsor: Pennington Biomedical Research Center; Other
Eligibility: 18 Years to 65 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Baton Rouge, Louisiana

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Diet as a Potential Treatment for Autosomal Dominant Polycystic Kidney Disease

Adrenocorticotropic Hormone Stimulation in Postural Orthostatic Tachycardia Syndrome (POTS)

Vascular Responses to Sympathetic Activation and Altered Shear Rate: The Impact of Hypertension and Sodium Intake

Orthostatic Hypotension Treatment on Rehab Unit

Nocturnal Hypertension and Non-Dipping Blood Pressure

Return of First-phase Insulin Secretion in Type 2 Diabetes is Associated With Depletion of Pancreas Lipid

Blood Pressure Response to Sodium in the Diet

Effect of Sodium Intake on Calcium Retention in Girls

When the Kidney Reacts to Nutritional Changes

Dietary Oxalate and Immune Cell Function

Low Sodium Oxybate in Patients With Idiopathic Hypersomnia

UrApp for Childhood Nephrotic Syndrome Management (Incident Cohort)

Exercise and QUality Diet After Leukemia: The EQUAL Study

The Salt Study for Heart Failure

Dietary Salt in Postural Tachycardia Syndrome

Human Sodium Balance Study

Translating Dietary Trials Into the Community

Volume,Sodium and Blood Pressure Management in HD

Shifting Salty Taste Preferences in Children

FIM+DASH: Food is Medicine Intervention to Promote Healthy Eating and Blood Pressure Control

MOBILE Intervention in College Students With Elevated Blood Pressure

Renal Salt Handling in Postural Tachycardia Syndrome Following Dietary Dopa Administration

Promoting Well-being and Health in Heart Failure

Nutrition for Asthmatics with Obesity