Independent directory Public ClinicalTrials.gov records United States
Clinical Trials Finder
Objective public record navigation
Search Results

Search by objective public record fields.

Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results come from ClinicalTrials.gov. When the live registry is unavailable, a clearly labeled stored copy may be shown.

Clear filters

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Oct 4, 2026, 10:34 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 206 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: melatonin (Circadin) Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Light Sensitization Study

NCT01327040
View directory record Official record
Conditions
Chronobiology Disorders, Circadian Rhythm Disorders, Sleep Disorders, Circadian Rhythm
Interventions
light exposure
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
21 Years to 30 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 1, 2021 · Synced Oct 4, 2026, 10:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Individually Tailored Lighting System to Improve Sleep in Older Adults

NCT01855126
View directory record Official record
Conditions
Sleep Disturbances
Interventions
Blue light, Red light
Other
Lead sponsor
Rensselaer Polytechnic Institute
Other
Eligibility
65 Years and older
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Troy, New York
Source: ClinicalTrials.gov public record
Updated Jan 29, 2019 · Synced Oct 4, 2026, 10:34 PM EDT
Completed Phase 2 Interventional Results available

Efficacy of Circadin® 2 mg in Patients With Mild to Moderate Alzheimer Disease Treated With AChE Inhibitor

NCT00940589
View directory record Official record
Conditions
Alzheimer's Disease, Sleep Disorder
Interventions
Circadin, Placebo
Drug
Lead sponsor
Neurim Pharmaceuticals Ltd.
Industry
Eligibility
50 Years to 85 Years
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
4
States / cities
Brooksville, Florida • St. Petersburg, Florida • Mount Arlington, New Jersey + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 1, 2018 · Synced Oct 4, 2026, 10:34 PM EDT
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Effect of Melatonin on Sleep Patterns of Resident Trainees During Night Float Shift

NCT05701969
View directory record Official record
Conditions
Sleep Disorders, Circadian Rhythm
Interventions
Melatonin, Placebo
Dietary Supplement · Other
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2028
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Oct 4, 2026, 10:34 PM EDT
Not listed No phase listed Observational

Observational Study to Investigate the Melatonin and Cortisol Circadian Rhythms of Individuals With Smith-Magenis Syndrome (SMS)

NCT02180451
View directory record Official record
Conditions
Smith Magenis Syndrome
Interventions
Not listed
Lead sponsor
Vanda Pharmaceuticals
Industry
Eligibility
6 Years to 50 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 25, 2016 · Synced Oct 4, 2026, 10:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effectiveness of a Proprietary of a Botanical Extract on Sleep Quality

NCT06894108
View directory record Official record
Conditions
Sleep
Interventions
Proprietary Blend of Botanical Extracts, Melatonin
Dietary Supplement
Lead sponsor
Nutraceuticals Research Institute
Other
Eligibility
35 Years to 55 Years · Female only
Enrollment
89 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Huntsville, Alabama
Source: ClinicalTrials.gov public record
Updated Sep 23, 2025 · Synced Oct 4, 2026, 10:34 PM EDT
Terminated Not applicable Interventional Results available

Blind Child Melatonin Treatment Study

NCT00691444
View directory record Official record
Conditions
Blindness
Interventions
Melatonin, Melatonin
Dietary Supplement · Biological
Lead sponsor
Oregon Health and Science University
Other
Eligibility
5 Years to 20 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2015
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 27, 2019 · Synced Oct 4, 2026, 10:34 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Effects of Melatonin on Sleep, Ventilatory Control and Cognition at Altitude.

NCT03368352
View directory record Official record
Conditions
Altitude Hypoxia, Ventilation, Sleep, Oxidative Stress, Neurocognitive Dysfunction
Interventions
Melatonin, Hypoxia
Dietary Supplement · Other
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jan 31, 2019 · Synced Oct 4, 2026, 10:34 PM EDT
Completed Phase 1 Interventional

Treatment Strategies for Children With Smith-Magenis Syndrome

NCT00506259
View directory record Official record
Conditions
Developmental Delay Disorders, Chromosome Deletion, Mental Retardation, Sleep Disorders, Circadian Rhythm, Self Injurious Behavior
Interventions
dTR Melatonin (NIH CC PDS), Phototherapy (Bright Light), Melatonin CR
Drug · Device
Lead sponsor
National Human Genome Research Institute (NHGRI)
NIH
Eligibility
3 Years to 45 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2018
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 12, 2019 · Synced Oct 4, 2026, 10:34 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Testing Effects of Melatonin on Uterine Contractions in Women

NCT05358834
View directory record Official record
Conditions
Pregnant Women
Interventions
Melatonin, Placebo
Dietary Supplement
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 35 Years · Female only
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Oct 4, 2026, 10:34 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Impact of Sleep Extension in Adolescents

NCT03500458
View directory record Official record
Conditions
Insulin Sensitivity, Sleep, Dietary Habits
Interventions
Sleep Extension
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
14 Years to 19 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2025
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 1, 2024 · Synced Oct 4, 2026, 10:34 PM EDT
Completed Phase 2 Interventional Results available

Bringing Relief to Adolescents Naturally Using Melatonin for Migraine

NCT02344316
View directory record Official record
Conditions
Migraine in Adolescents
Interventions
Melatonin, Placebo
Drug · Other
Lead sponsor
Amy Gelfand
Other
Eligibility
12 Years to 17 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
2
States / cities
Los Angeles, California • San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 9, 2021 · Synced Oct 4, 2026, 10:34 PM EDT
Completed Phase 2 Interventional

RECOVER-SLEEP: Platform Protocol, Appendix_B (CPSD)

NCT06404112
View directory record Official record
Conditions
Long COVID, Long COVID-19, Sleep Disturbance
Interventions
Melatonin, Melantonin Placebo, Tailored lighting (TL) Active, Tailored lighting (TL) Placebo
Drug · Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
469 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Oct 4, 2026, 10:34 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Melatonin Studies of Totally Blind Children

NCT00795236
View directory record Official record
Conditions
Sleep Disorder, Blindness
Interventions
Melatonin
Drug
Lead sponsor
Oregon Health and Science University
Other
Eligibility
5 Years to 20 Years
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2015
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 27, 2019 · Synced Oct 4, 2026, 10:34 PM EDT
Recruiting No phase listed Observational

Advancing Identification of Circadian Delay in ADHD Youth: Associations With Clinical Heterogeneity and Cognition

NCT06971640
View directory record Official record
Conditions
ADHD - Attention Deficit Disorder With Hyperactivity, ADHD
Interventions
Not listed
Lead sponsor
Duke University
Other
Eligibility
6 Years to 9 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Oct 4, 2026, 10:34 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Effects of Sex Hormones on Circadian Rhythm in Men and Women

NCT00001285
View directory record Official record
Conditions
Bipolar Disorder, Circadian Rhythm, Depressive Disorder
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
Female only
Enrollment
73 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1991 – 2000
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 4, 2026, 10:34 PM EDT
Not listed Phase 4 Interventional

Effects of Ramelteon (8mg) Alone and in Combination With Multi-Component Behavioral Therapy on Sleep and Circadian Phase in Patients With Chronic Insomnia

NCT01180855
View directory record Official record
Conditions
Insomnia
Interventions
Placebo, Rozerem 8mg, Rozerem 8mg in combination with Multi Component Behavior Therapy
Drug · Other
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 64 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 12, 2010 · Synced Oct 4, 2026, 10:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pharmacotherapy and Mechanisms of Sleep Disturbance in Alcohol Dependence

NCT01014533
View directory record Official record
Conditions
Alcohol Dependence, Insomnia
Interventions
Placebo dispensed to subject., Gabapentin dispensed to subject.
Drug
Lead sponsor
Dr. Kirk Brower
Other
Eligibility
18 Years to 65 Years
Enrollment
59 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2011
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 6, 2017 · Synced Oct 4, 2026, 10:34 PM EDT
Recruiting Phase 3 Interventional

Sleep Quality and the Efficacy of a Multimodal Sleep Pathway in Hospitalized Orthopedic Trauma Patients

NCT07336277
View directory record Official record
Conditions
Orthopedic Trauma, Sleep Quality
Interventions
Standard Postoperative Care, Zolpidem, Melatonin, Sleep Hygiene Education, Actigraph GT3X-BT Actigraph
Other · Drug · Dietary Supplement + 2 more
Lead sponsor
Emory University
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 30, 2026 · Synced Oct 4, 2026, 10:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Different Colors of Light on Human Physiology

NCT00200863
View directory record Official record
Conditions
Healthy, Circadian Rhythm
Interventions
Monochromatic visible light exposure
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 30 Years
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 12, 2014 · Synced Oct 4, 2026, 10:34 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Impact of Room Light on Uterine Contractions and Labor Progression in Pregnancy

NCT04521972
View directory record Official record
Conditions
Pregnancy Related, Labor; Poor, Uterine Contractions Weak
Interventions
Room light/light bulb
Device
Lead sponsor
Michigan State University
Other
Eligibility
18 Years to 42 Years · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
East Lansing, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 18, 2025 · Synced Oct 4, 2026, 10:34 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Neurobiological Effects of Light on MDD

NCT02940769
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
light glasses, sham glasses (placebo)
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 60 Years
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 22, 2022 · Synced Oct 4, 2026, 10:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of Light on Melatonin and Contractions in Pregnant Women

NCT01863446
View directory record Official record
Conditions
Pregnancy
Interventions
Lighting1, Lighting2
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 35 Years · Female only
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 27, 2024 · Synced Oct 4, 2026, 10:34 PM EDT
Withdrawn Not applicable Interventional

Melatonin in Acute Stroke

NCT03843008
View directory record Official record
Conditions
Stroke, Acute, Ischemic Stroke
Interventions
Melatonin
Dietary Supplement
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 26, 2024 · Synced Oct 4, 2026, 10:34 PM EDT