- Conditions
- Abdominal Pain
- Interventions
- S-adenosyl methionine
- Drug
- Lead sponsor
- Huang, Jeannie, M.D.
- Individual
- Eligibility
- 8 Years to 22 Years
- Enrollment
- 8 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2012
- U.S. locations
- 1
- States / cities
- San Diego, California
Search Results
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Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.
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Showing 25–48
of 24
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- HIV-1 Infection
- Interventions
- Zinc and SAMe
- Dietary Supplement
- Lead sponsor
- Emory University
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 67 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2018
- U.S. locations
- 1
- States / cities
- Atlanta, Georgia
- Conditions
- Newly Diagnosed Glioblastoma
- Interventions
- SurVaxM
- Biological
- Lead sponsor
- MimiVax, LLC
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 247 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2024
- U.S. locations
- 11
- States / cities
- San Francisco, California • Miami, Florida • Louisville, Kentucky + 7 more
- Conditions
- Vitamin B6 Deficiency
- Interventions
- Arm 1 glycine and leucine, Arm 2 Intervention of Serine and methionine infusion
- Dietary Supplement
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 20 Years to 40 Years
- Enrollment
- 45 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2008 – 2010
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
- Conditions
- Sleep Disturbances
- Interventions
- S-Adenosyl Methionine (SAMe), Propyl Gallate, Gamma-Aminobutyric Acid (GABA), L-Theanine, and Magnesium Glycinate
- Dietary Supplement
- Lead sponsor
- Bonafide Health
- Industry
- Eligibility
- 40 Years to 65 Years · Female only
- Enrollment
- 90 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025
- U.S. locations
- 1
- States / cities
- Harrison, New York
- Conditions
- Brain Metastasis
- Interventions
- Standard of Care FDG-PET Imaging
- Procedure
- Lead sponsor
- Yale University
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 8 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2017
- U.S. locations
- 1
- States / cities
- New Haven, Connecticut
- Conditions
- Chronic Obstructive Pulmonary Disease
- Interventions
- acute resistance exercise with oral nutrition supplementation, stable tracer infusion
- Other
- Lead sponsor
- Texas A&M University
- Other
- Eligibility
- 45 Years to 100 Years
- Enrollment
- 16 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2020
- U.S. locations
- 1
- States / cities
- College Station, Texas
- Conditions
- Myelopathy, AIDS-Myelopathy, AIDS Vacuolar Myelopathy
- Interventions
- methionine
- Drug
- Lead sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
- NIH
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 56 participants
- Healthy volunteers
- Healthy volunteers not accepted
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Prostate Cancer
- Interventions
- positron emission tomography, fludeoxyglucose F 18, methionine C 11
- Procedure · Radiation
- Lead sponsor
- Memorial Sloan Kettering Cancer Center
- Other
- Eligibility
- 0 Years to 120 Years · Male only
- Enrollment
- 173 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 1997 – 2023
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Pulmonary Disease, Chronic Obstructive
- Interventions
- stable amino acid infusion, acute exercise with amino acid infusion, 24-hour post exercise amino acid infusion
- Other
- Lead sponsor
- Texas A&M University
- Other
- Eligibility
- 45 Years and older
- Enrollment
- 57 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016 – 2020
- U.S. locations
- 1
- States / cities
- College Station, Texas
- Conditions
- Rhabdomyosarcoma
- Interventions
- Vincristine, Dactinomycin, Cyclophosphamide, Surgical Resection, Radiation, Bevacizumab, Sorafenib, Myeloid Growth Factor, Lymph Node Sampling, Irinotecan, Ifosfamide, Etoposide, Etoposide Phosphate, Doxorubicin, Dexrazoxane, ^1^1C-methionine
- Drug · Procedure
- Lead sponsor
- St. Jude Children's Research Hospital
- Other
- Eligibility
- Up to 21 Years
- Enrollment
- 115 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2030
- U.S. locations
- 4
- States / cities
- Jacksonville, Florida • Memphis, Tennessee • Fort Worth, Texas
- Conditions
- Effect of Selenium on Oxidative Stress in Healthy Men
- Interventions
- Placebo, selenomethionine, low dose selenized-yeast, high dose selenized-yeast
- Other · Dietary Supplement
- Lead sponsor
- Milton S. Hershey Medical Center
- Other
- Eligibility
- 20 Years to 79 Years · Male only
- Enrollment
- 130 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2008 – 2014
- U.S. locations
- 1
- States / cities
- Hershey, Pennsylvania
- Conditions
- Parkinson's Disease, Depression
- Interventions
- SAM-e, oral escitalopram, placebo
- Drug
- Lead sponsor
- NYU Langone Health
- Other
- Eligibility
- 30 Years to 80 Years
- Enrollment
- 29 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2003 – 2010
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Liver Cirrhosis, Biliary
- Interventions
- S-adenosyl-methionine (SAMe) capsules
- Drug
- Lead sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
- NIH
- Eligibility
- 21 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2008
- U.S. locations
- 1
- States / cities
- Bethesda, Maryland
- Conditions
- Adult Primary Liver Cancer, Hepatitis C Infection
- Interventions
- S-adenosyl-L-methionine disulfate p-toluene-sulfonate, placebo, laboratory biomarker analysis, immunoenzyme technique, high performance liquid chromatography
- Drug · Other
- Lead sponsor
- Chao Family Comprehensive Cancer Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 110 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2013
- U.S. locations
- 5
- States / cities
- Tucson, Arizona • Long Beach, California • Los Angeles, California + 2 more
- Conditions
- Neuroblastoma
- Interventions
- buthionine sulfoximine, melphalan, Peripheral blood stem cell infusion, Filgrastim
- Drug · Procedure · Other
- Lead sponsor
- New Approaches to Neuroblastoma Therapy Consortium
- Other
- Eligibility
- Up to 30 Years
- Enrollment
- 31 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2001 – 2016
- U.S. locations
- 8
- States / cities
- Los Angeles, California • San Francisco, California • Chicago, Illinois + 5 more
- Conditions
- Neuroblastoma
- Interventions
- buthionine sulfoximine, melphalan
- Drug
- Lead sponsor
- New Approaches to Neuroblastoma Therapy Consortium
- Other
- Eligibility
- 0 Years to 21 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 1996
- U.S. locations
- 4
- States / cities
- Los Angeles, California • San Francisco, California • Minneapolis, Minnesota + 1 more
- Conditions
- Melanoma (Skin)
- Interventions
- buthionine sulfoximine, melphalan, microarray analysis, high performance liquid chromatography, laboratory biomarker analysis, pharmacological study, biopsy
- Drug · Genetic · Other + 1 more
- Lead sponsor
- Duke University
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2008
- U.S. locations
- 2
- States / cities
- Durham, North Carolina • Houston, Texas
- Conditions
- Bipolar Disorder, Depression, Bipolar Depression
- Interventions
- SAMe, Placebo
- Drug
- Lead sponsor
- Mclean Hospital
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 23 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2011
- U.S. locations
- 1
- States / cities
- Belmont, Massachusetts
- Conditions
- Obesity, Over-weight, Hypothalamic Injury, Craniopharyngioma
- Interventions
- ZGN-440 sterile diluent, ZGN-440 for injectable suspension
- Drug
- Lead sponsor
- Zafgen, Inc.
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 14 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014
- U.S. locations
- 2
- States / cities
- Saint Paul, Minnesota • Nashville, Tennessee
- Conditions
- Advanced Metastatic Clear Cell Renal Cell Carcinoma (CCRCC)
- Interventions
- Selenomethionine (SLM), Axitinib
- Drug
- Lead sponsor
- Mohammed Milhem
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 45 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2025
- U.S. locations
- 1
- States / cities
- Iowa City, Iowa
- Conditions
- Locally Advanced/Metastatic Solid Tumors
- Interventions
- ISM3412
- Drug
- Lead sponsor
- InSilico Medicine Hong Kong Limited
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 146 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2029
- U.S. locations
- 5
- States / cities
- Denver, Colorado • New Haven, Connecticut • Indianapolis, Indiana + 2 more
- Conditions
- Alcoholic Cirrhosis
- Interventions
- Placebo, SAMe 400 mg tablet
- Drug
- Lead sponsor
- Indiana University
- Other
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 196 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2027
- U.S. locations
- 2
- States / cities
- Los Angeles, California • Indianapolis, Indiana
- Conditions
- Osteoarthritis Hand
- Interventions
- S-Adenosyl-L-Methionine (Sam-E), Placebo
- Drug
- Lead sponsor
- Dartmouth-Hitchcock Medical Center
- Other
- Eligibility
- 40 Years and older
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2025
- U.S. locations
- 1
- States / cities
- Lebanon, New Hampshire