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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: mifepristone Clear all
Withdrawn Phase 1 Interventional Accepts healthy volunteers

Second Trimester Labor Induction

NCT00592215
View directory record Official record
Conditions
Second Trimester Labor Induction
Interventions
Experimental (mifepristone and misoprostol)
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 50 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
2
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 7, 2017 · Synced Sep 17, 2026, 5:22 AM EDT
Terminated Phase 2 Interventional Results available

Mifepristone Dynamic Testing for Diagnosis for Central Adrenal Insufficiency

NCT04588688
View directory record Official record
Conditions
Central Adrenal Insufficiency, Mifepristone
Interventions
Mifepristone
Drug
Lead sponsor
Tobias Else
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 11, 2023 · Synced Sep 17, 2026, 5:22 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Mifepristone at Same Time Multicenter Study

NCT00269568
View directory record Official record
Conditions
Abortion Seekers
Interventions
mifepristone and misoprostol
Drug
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
1,128 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2006
U.S. locations
4
States / cities
Los Angeles, California • Chicago, Illinois • Portland, Oregon + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 28, 2016 · Synced Sep 17, 2026, 5:22 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Clinical Trial of Mifepristone for Bipolar Depression

NCT00043654
View directory record Official record
Conditions
Bipolar Disorder
Interventions
Mifepristone
Drug
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
18 Years to 75 Years
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2007
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Sep 17, 2026, 5:22 AM EDT
Completed No phase listed Observational

Mifepristone and Misoprostol for the Termination of Pregnancy up to 70 Days Gestation

NCT01966874
View directory record Official record
Conditions
Medical; Abortion, Fetus
Interventions
Not listed
Lead sponsor
Gynuity Health Projects
Other
Eligibility
Female only
Enrollment
1,001 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 21, 2013 · Synced Sep 17, 2026, 5:22 AM EDT
Completed Not applicable Interventional Results available

Mifepristone Treatment for Patients With Non-psychotic Major Depressive Disorder Receiving Bilateral ECT

NCT00285818
View directory record Official record
Conditions
Depression
Interventions
Mifepristone, Placebo Oral Capsule
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 75 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2009
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Feb 15, 2017 · Synced Sep 17, 2026, 5:22 AM EDT
Completed Phase 2 Interventional Results available

Medication Development in Alcoholism: Investigating Glucocorticoid Antagonists

NCT01548417
View directory record Official record
Conditions
Alcoholism
Interventions
Korlym (mifepristone), Sugar Pill
Drug
Lead sponsor
The Scripps Research Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jun 23, 2016 · Synced Sep 17, 2026, 5:22 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Mifepristone Versus Misoprostol for Cervical Preparation Prior to Surgical Abortion Between 11 to 15 Weeks

NCT01636063
View directory record Official record
Conditions
Induced Abortion, Abortion Techniques, Mifepristone, Misoprostol
Interventions
Mifepristone, Misoprostol
Drug
Lead sponsor
Boston University
Other
Eligibility
18 Years and older · Female only
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 21, 2017 · Synced Sep 17, 2026, 5:22 AM EDT
Completed Phase 2 Interventional Results available

Mifepristone Treatment of Alcohol Use Disorder

NCT02179749
View directory record Official record
Conditions
Alcohol Dependence, Alcohol Use Disorders, Alcohol Abuse, Alcoholism
Interventions
Mifepristone 1200 mg daily, Standardized behavioral therapy, Placebo
Drug · Behavioral
Lead sponsor
The Scripps Research Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Oct 5, 2022 · Synced Sep 17, 2026, 5:22 AM EDT
Completed Phase 3 Interventional

A United States Study of Corlux for Psychotic Symptoms in Psychotic Major Depression

NCT00130676
View directory record Official record
Conditions
Major Depressive Disorder, Psychotic Disorders
Interventions
Mifepristone, matching placebo
Drug
Lead sponsor
Corcept Therapeutics
Industry
Eligibility
18 Years to 75 Years
Enrollment
257 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
23
States / cities
Pico Rivera, California • Riverside, California • San Diego, California + 20 more
Source: ClinicalTrials.gov public record
Updated Feb 14, 2012 · Synced Sep 17, 2026, 5:22 AM EDT
Completed Not applicable Interventional

Medical Abortion Self-Confirmation (MASC)

NCT03148587
View directory record Official record
Conditions
Medical Abortion
Interventions
Self-assessment: MLPT, Self-assessment: LSPT
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jun 6, 2019 · Synced Sep 17, 2026, 5:22 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Pilot Study of Pharmaceutical and Behavioral Interventions to Treat Anxiety Disorders

NCT01631682
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Anxiety Disorder
Interventions
Propranolol, Reactivation, Mifepristone, Intranasal oxytocin
Drug · Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 35 Years
Enrollment
186 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2015
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 22, 2017 · Synced Sep 17, 2026, 5:22 AM EDT
Completed Phase 2Phase 3 Interventional Results available

Investigation of Mifepristone (RU486) on Stress Sensitivity and Relapse Prevention in Cocaine Dependent Patients

NCT01134198
View directory record Official record
Conditions
Cocaine Dependence
Interventions
Mifepristone, placebo
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 60 Years · Male only
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 19, 2018 · Synced Sep 17, 2026, 5:22 AM EDT
Terminated Phase 3 Interventional Results available

Treatment of Psychotic Major Depression With Mifepristone

NCT00867360
View directory record Official record
Conditions
Affective Disorders, Psychotic, Depressive Disorder
Interventions
Mifepristone (RU-486), Placebo
Drug
Lead sponsor
Stanford University
Other
Eligibility
21 Years to 85 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Apr 3, 2017 · Synced Sep 17, 2026, 5:22 AM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Period Pills for Menstrual Regulation: A New Reproductive Health Option

NCT07671989
View directory record Official record
Conditions
Menstrual Regulation, Menstrual Health Intervention
Interventions
Mifepristone + Misoprostol
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
2
States / cities
Oakland, California • Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Sep 17, 2026, 5:22 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Effects of Mifepristone on Biomarkers of Metabolic Function and Neuropsychological Performance Among Middle-Aged and Older Individuals

NCT01988610
View directory record Official record
Conditions
Depression
Interventions
28 days treatment with Mifepristone.
Drug
Lead sponsor
Stanford University
Other
Eligibility
50 Years to 70 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jan 24, 2018 · Synced Sep 17, 2026, 5:22 AM EDT
Terminated Phase 2 Interventional Results available

Prospective, Open-Label, Multicenter, International Study of Mifepristone for Symptomatic Treatment of Cushing's Syndrome Caused by Ectopic Adrenal Corticotrophin Hormone (ACTH) Secretion

NCT00422201
View directory record Official record
Conditions
Cushing's Syndrome
Interventions
Mifepristone
Drug
Lead sponsor
HRA Pharma
Industry
Eligibility
18 Years to 85 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 10, 2019 · Synced Sep 17, 2026, 5:22 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

MiMi: A Randomized Trial of Mifepristone and Misoprostol for Treatment of Early Pregnancy Failure

NCT00468299
View directory record Official record
Conditions
Early Pregnancy Failure, Miscarriage, Fetal Demise, Anembryonic Pregnancy
Interventions
Misoprostol and placebo, Mifepristone and misoprostol
Drug
Lead sponsor
Boston University
Other
Eligibility
18 Years to 64 Years · Female only
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 20, 2011 · Synced Sep 17, 2026, 5:22 AM EDT
Withdrawn Not applicable Interventional

Mifepristone Versus Osmotic Dilators in Conjunction With Misoprostol for Cervical Preparation Prior to D&E at 14-19 Weeks

NCT02679092
View directory record Official record
Conditions
Legally Induced Abortion Without Mention of Complication
Interventions
Misoprostol, Mifepristone, Hygroscopic cervical dilators
Drug · Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
San Jose, California
Source: ClinicalTrials.gov public record
Updated Sep 18, 2019 · Synced Sep 17, 2026, 5:22 AM EDT
Completed Phase 1 Interventional

A Clinical Trial for Post Traumatic Stress Disorder

NCT00554177
View directory record Official record
Conditions
Post Traumatic Stress Disorder (PTSD)
Interventions
Medicane (mifepristone), Placebo
Drug
Lead sponsor
Antonia New
Other
Eligibility
18 Years to 65 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 16, 2016 · Synced Sep 17, 2026, 5:22 AM EDT
Completed Phase 3 Interventional Results available

Mifepristone Versus Osmotic Dilator Insertion for Cervical Preparation Prior to Surgical Abortion at 15-18 Weeks

NCT01436279
View directory record Official record
Conditions
Cervical Preparation
Interventions
Mifepristone, osmotic dilators
Drug · Device
Lead sponsor
Boston University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 13, 2017 · Synced Sep 17, 2026, 5:22 AM EDT
Completed Not applicable Interventional

Patient Agreement Form and Medication Abortion Knowledge

NCT07604675
View directory record Official record
Conditions
Medication Abortion, Health Knowledge Attitudes and Practice, Pregnant People
Interventions
Patient Agreement Form (PAF)
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
15 Years and older · Female only
Enrollment
637 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
5
States / cities
San Francisco, California • Denver, Colorado • Carbondale, Illinois + 2 more
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Sep 17, 2026, 5:22 AM EDT
Completed No phase listed Observational

Same-day Long-acting Reversible Contraception for Medication Abortion

NCT01356927
View directory record Official record
Conditions
Abortion; Induced
Interventions
DMPA, Etonogestrel implant
Drug
Lead sponsor
Boston University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 6, 2017 · Synced Sep 17, 2026, 5:22 AM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers

Medication Enhanced Rapid Therapy

NCT02099825
View directory record Official record
Conditions
Anxiety Disorders
Interventions
d-cycloserine and mifepristone
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 55 Years · Male only
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 25, 2023 · Synced Sep 17, 2026, 5:22 AM EDT