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ClinicalTrials.gov public records Last synced Oct 23, 2026, 1:27 AM EDT

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Showing 97–120 of 217 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: mild exercise Clear all
Recruiting Phase 1 Interventional Accepts healthy volunteers

: Vascular Function in Health and Disease

NCT02966665
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease, Pulmonary Artery Hypertension, Heart Failure, Hypertension
Interventions
Maximum Exercise Tests, BH4, L-NMMA, Vitamin C, Vitamin E, α-Lipoic Acid and L-Ascorbate, BQ-123, Fexofenadine, Ranitidine, Angiotensin-II, Valsartan, Acetylcholine, Sodium Nitroprusside, Angiotensin-II, Norepinephrine, Phentolamine, BQ-123, MitoQ, BH4
Other · Drug
Lead sponsor
D. Walter Wray
Other
Eligibility
18 Years and older
Enrollment
420 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2030
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 23, 2026, 1:27 AM EDT
Completed Not applicable Interventional Results available

Effects of Walkasins on Gait Speed of Individuals With Mild Cognitive Impairments

NCT05723822
View directory record Official record
Conditions
Mild Cognitive Impairment, Cognitive Decline, Gait Disorders in Old Age
Interventions
Walkasins
Device
Lead sponsor
RxFunction Inc.
Industry
Eligibility
65 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 5, 2023 · Synced Oct 23, 2026, 1:27 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Atlas of Retinal Imaging in Alzheimer's Study

NCT03862222
View directory record Official record
Conditions
Alzheimer Disease, Mild Cognitive Impairment, Mild Dementia, Aging, Cognitive Change
Interventions
Retinal Imaging, Pupillometry, Contrast Sensitivity, Neuropsychological Evaluation, APOE genotyping, blood draw, Gait Assessment, Actigraphy
Other · Diagnostic Test · Genetic
Lead sponsor
University of Rhode Island
Other
Eligibility
55 Years to 80 Years
Enrollment
165 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
4
States / cities
Clearwater, Florida • St. Petersburg, Florida • Kingston, Rhode Island + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 5, 2025 · Synced Oct 23, 2026, 1:27 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Working Memory and Physical Exercise Training in Patients With Mild Cognitive Impairment

NCT05948930
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
Progressive aerobic exercise, Adaptive cognitive training, Combined
Behavioral
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
50 Years to 80 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 12, 2026 · Synced Oct 23, 2026, 1:27 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Normative Database and Test-Retest Reliability for BrainCheck Assessments

NCT05497427
View directory record Official record
Conditions
Cognitive Change, Cognitive Decline, Cognitive Deterioration, Neurocognitive Deficit
Interventions
BrainCheck Assessment
Device
Lead sponsor
BrainCheck, Inc.
Other
Eligibility
50 Years and older
Enrollment
1,300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
5
States / cities
Palo Alto, California • Multiple Locations, Connecticut • Austin, Texas + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 2, 2026 · Synced Oct 23, 2026, 1:27 AM EDT
Completed Phase 2 Interventional

A Pilot Study Comparing Nebivolol and Atenolol and Its Effects With Exercise in Patients With Mild to Moderate Hypertension

NCT00200421
View directory record Official record
Conditions
Hypertension
Interventions
Nebivolol and Atenolol
Drug
Lead sponsor
Mylan Bertek Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2003
U.S. locations
1
States / cities
Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Dec 16, 2005 · Synced Oct 23, 2026, 1:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of a Complex, Partnered Martial Arts-based Intervention on Cognitive Processing.

NCT05530148
View directory record Official record
Conditions
Cognitive Change, Processing, Visual Spatial
Interventions
Martial Arts Training Group, Flexing, Toning and Balance
Behavioral
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
18 Years to 45 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated May 11, 2023 · Synced Oct 23, 2026, 1:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Fatigue Countermeasure Program in Operational Flight Controllers

NCT01744678
View directory record Official record
Conditions
Fatigue
Interventions
blue-wavelength enriched ceiling light, mild exercise
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 18, 2019 · Synced Oct 23, 2026, 1:27 AM EDT
Recruiting Phase 1Phase 2 Interventional

Sense4Safety Intervention

NCT07220668
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
Sense4Safety
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
65 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 19, 2026 · Synced Oct 23, 2026, 1:27 AM EDT
Completed No phase listed Observational

The Relationship Between Having a Positive Mindset and Exercise Capacity in Patients With Congenital Heart Disease

NCT03912025
View directory record Official record
Conditions
Congenital Heart Disease
Interventions
Relationship between positive mindset and exercise capacity
Other
Lead sponsor
Boston Children's Hospital
Other
Eligibility
8 Years to 17 Years
Enrollment
90 participants
Timeline
2020 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 4, 2021 · Synced Oct 23, 2026, 1:27 AM EDT
Completed Not applicable Interventional

A Health Game Intervention for Cancer and Post-ICU Patients Suffering From Acute Cognitive Impairment

NCT07596940
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
VR cognitive training platform
Device
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Oct 23, 2026, 1:27 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Early Detection of Pulmonary Arterial Hypertension Using Cardiac Magnetic Resonance Imaging

NCT01451255
View directory record Official record
Conditions
Pulmonary Hypertension, Pulmonary Arterial Hypertension
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 99 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
2
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 17, 2016 · Synced Oct 23, 2026, 1:27 AM EDT
Completed Phase 2 Interventional Results available

A Clinical Trial to Test a Study Drug in Volunteers Who Develop Asthma Following Exercise

NCT00812929
View directory record Official record
Conditions
Asthma
Interventions
Placebo, GSK2190915
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 55 Years
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
6
States / cities
Denver, Colorado • North Dartmouth, Massachusetts • Oklahoma City, Oklahoma + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 19, 2017 · Synced Oct 23, 2026, 1:27 AM EDT
Completed Not applicable Interventional Results available

Preventing Loss of Independence Through Exercise (PLIÉ) in Persons With Mild Cognitive Impairment (MCI)

NCT03526146
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
Behavioral: Preventing Loss of Independence through Exercise (PLIE)
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
50 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 10, 2025 · Synced Oct 23, 2026, 1:27 AM EDT
Completed Not applicable Interventional Results available

Multifamily Group to Reduce Marital Conflict and Disability in Veterans With mTBI

NCT02057081
View directory record Official record
Conditions
Mild Traumatic Brain Injury, Posttraumatic Stress Disorders, Depression
Interventions
Multifamily Group for mTBI for Couples, Group Health Education (GHE)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
249 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
3
States / cities
Baltimore, Maryland • New York, New York • The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jun 4, 2020 · Synced Oct 23, 2026, 1:27 AM EDT
Recruiting Not applicable Interventional

Improve New Learning and Memory in Individuals With Mild Cognitive Impairment

NCT05396248
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
Memory Retraining Exercises, Placebo Control Memory Exercises
Behavioral
Lead sponsor
Kessler Foundation
Other
Eligibility
60 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
2
States / cities
Ann Arbor, Michigan • West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Oct 23, 2026, 1:27 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Integrative Therapy for Holistic, Natural Cognition and Lifestyle Rehabilitation

NCT04284449
View directory record Official record
Conditions
Cognitive Dysfunction
Interventions
Whole-practice cognitive optimization
Other
Lead sponsor
National University of Natural Medicine
Other
Eligibility
60 Years and older
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Encinitas, California
Source: ClinicalTrials.gov public record
Updated Aug 6, 2024 · Synced Oct 23, 2026, 1:27 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Personalized Closed-Loop Brain Stimulation for Patients With Mild Cognitive Impairment

NCT07512193
View directory record Official record
Conditions
MCI
Interventions
Active tES, Cognitive Interventions
Device · Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
45 Years to 85 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 7, 2026 · Synced Oct 23, 2026, 1:27 AM EDT
Completed Not applicable Interventional

Effect of Myofunctional Therapy on OSA

NCT04608552
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
OMT Exercises, Nasal Breathing Exercises, Use of Nasal Lavage
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 70 Years
Enrollment
209 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jan 8, 2026 · Synced Oct 23, 2026, 1:27 AM EDT
Completed Not applicable Interventional

Concussion Treatment in Older Adults

NCT05849064
View directory record Official record
Conditions
Concussion, Mild
Interventions
Behavioral Control, Targeted Intervention
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
50 Years to 99 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Oct 23, 2026, 1:27 AM EDT
Completed Not applicable Interventional

Exercise and Activities for Independent Living With Mild Cognitive Impairment (MCI)

NCT00446394
View directory record Official record
Conditions
Mild Cognitive Impairment, Dementia
Interventions
Resources and Activities for Life Long Independence (RALLI), Social Walking program (SW)
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
70 Years and older
Enrollment
181 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 19, 2012 · Synced Oct 23, 2026, 1:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effectiveness of Alternative Therapy for Improving Cognition, Balance, and Physical Activity

NCT04160299
View directory record Official record
Conditions
Mild Cognitive Impairment, Older Adults, Neurological Injury
Interventions
Dance-based exergaming
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
65 Years to 90 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 16, 2024 · Synced Oct 23, 2026, 1:27 AM EDT
Completed Phase 3 Interventional

Precision Medicine Approach for Early Dementia & Mild Cognitive Impairment

NCT05894954
View directory record Official record
Conditions
Mild Cognitive Impairment, Dementia, Mild
Interventions
Precision Medicine Approach, Hormones and Medications tailored to lab tests, combined with devices that support stress management and brain exercises, Standard-of-Care, Lifestyle including diet, exercise, stress management
Dietary Supplement · Combination Product · Behavioral
Lead sponsor
Alzheimer's Prevention and Reversal Project, Inc.
Other
Eligibility
45 Years to 76 Years
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
6
States / cities
Folsom, California • San Rafael, California • Walnut Creek, California + 3 more
Source: ClinicalTrials.gov public record
Updated Feb 18, 2026 · Synced Oct 23, 2026, 1:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Platform-based Mild Cognitive Impairment (MCI) Trial

NCT03987464
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
Planning for the Future, Enhanced Medical Engagement, Confidence Building and Social Engagement, Physical Intervention, Medical Adherence
Behavioral
Lead sponsor
Allison Gibson
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Feb 25, 2022 · Synced Oct 23, 2026, 1:27 AM EDT