- Conditions
- Neonatal Encephalopathy, Hypothermia Neonatal, Magnetic Resonance Spectroscopy
- Interventions
- Therapeutic hypothermia
- Other
- Lead sponsor
- Thayyil, Sudhin
- Individual
- Eligibility
- Up to 6 Hours
- Enrollment
- 140 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2024
- U.S. locations
- 1
- States / cities
- Michigan Center, Michigan
Search Results
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Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.
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Showing 1–22
of 22
matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
- Conditions
- Ischemic Stroke, Hypothermia
- Interventions
- Normothermia, Mild hypothermia, Trevo Pro Retriever (Stryker Corp.), Zoll Thermogard XP technology with the Quattro catheter
- Procedure · Device
- Lead sponsor
- WellStar Health System
- Other
- Eligibility
- 18 Years to 79 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2017
- U.S. locations
- 1
- States / cities
- Marietta, Georgia
- Conditions
- COVID19 ARDS
- Interventions
- Hypothermia Via Cooling Machine- Arctic Sun 5000
- Other
- Lead sponsor
- Northwell Health
- Other
- Eligibility
- 18 Years to 100 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020
- U.S. locations
- 1
- States / cities
- Manhasset, New York
- Conditions
- Septic Shock
- Interventions
- Mild Induced Hypothermia
- Procedure
- Lead sponsor
- Danish Procalcitonin Study Group
- Other
- Eligibility
- 50 Years to 120 Years
- Enrollment
- 433 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2016
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Tinnitus, Tinnitus, Subjective
- Interventions
- Cold pack-delivered mild therapeutic hypothermia, Sham device
- Device
- Lead sponsor
- Restorear Devices LLC
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Miami, Florida
- Conditions
- Cochlear Implants, Cochlear Implantation, Hearing Loss
- Interventions
- Intra-Ear Canal Cooling Catheter
- Device
- Lead sponsor
- Restorear Devices LLC
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 54 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2027
- U.S. locations
- 1
- States / cities
- Miami, Florida
- Conditions
- Organ Transplantation From Brain-dead Donors
- Interventions
- Cold isotonic fluid and central venous hypothermia catheter
- Other
- Lead sponsor
- University of Pittsburgh
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 4 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2014
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Hypoxic-Ischemic Encephalopathy, Brain Injury, Neonatal Seizure
- Interventions
- Neurologic examination
- Other
- Lead sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
- Other
- Eligibility
- Up to 6 Hours
- Enrollment
- 63 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2017
- U.S. locations
- 4
- States / cities
- Detroit, Michigan • Columbus, Ohio • Providence, Rhode Island + 1 more
- Conditions
- Ischemic Stroke, Hypothermia
- Interventions
- Mild Hypothermia
- Other
- Lead sponsor
- WellStar Health System
- Other
- Eligibility
- 18 Years to 85 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2015
- U.S. locations
- 1
- States / cities
- Atlanta, Georgia
- Conditions
- Out-of-hospital Cardiac Arrest
- Interventions
- Targeted temperature management to 33°C, Standard care with early treatment of fever
- Procedure
- Lead sponsor
- Helsingborgs Hospital
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 1,900 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2022
- U.S. locations
- 2
- States / cities
- Rochester, New York • Pittsburgh, Pennsylvania
- Conditions
- Healthy
- Interventions
- Cooling pack activated Excel Cryo Cooling Collar
- Device
- Lead sponsor
- University of Vermont
- Other
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 6 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2016
- U.S. locations
- 1
- States / cities
- Burlington, Vermont
- Conditions
- Thoracic Aortic Disease
- Interventions
- Hypothermic circulatory arrest
- Procedure
- Lead sponsor
- Ottawa Heart Institute Research Corporation
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 282 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2030
- U.S. locations
- 3
- States / cities
- Boston, Massachusetts • Ridgewood, New Jersey • Columbus, Ohio
- Conditions
- Cirrhosis, End Stage Liver Disease, Acute Kidney Injury, Liver Transplant; Complications, Chronic Kidney Diseases, Hepatitis c, Hepatitis B, NASH - Nonalcoholic Steatohepatitis, Alcoholic Cirrhosis, Hepatocellular Carcinoma
- Interventions
- Esophageal cooling/warming device, Mild hypothermia, Normothermia
- Device · Other
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 175 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2023
- U.S. locations
- 3
- States / cities
- San Francisco, California • Aurora, Colorado • Houston, Texas
- Conditions
- Noise Exposure, Noise-induced Hearing Loss, Noise; Adverse Effect, Mild Therapeutic Hypothermia, Cooling, Occupational Exposure, Occupational Health, Hidden Hearing Loss
- Interventions
- Cold pack-delivered mild therapeutic hypothermia
- Device
- Lead sponsor
- Restorear Devices LLC
- Industry
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 116 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2027
- U.S. locations
- 1
- States / cities
- Miami, Florida
- Conditions
- Hypoxic-Ischemic Encephalopathy Mild, Neonatal Encephalopathy
- Interventions
- Therapeutic Hypothermia, Normothermia
- Other
- Lead sponsor
- Stanford University
- Other
- Eligibility
- Up to 6 Hours
- Enrollment
- 68 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2025
- U.S. locations
- 5
- States / cities
- Loma Linda, California • Oakland, California • Orange, California + 2 more
- Conditions
- Mild Hypoxic Ischemic Encephalopathy of Newborn
- Interventions
- Normothermia, Whole body therapeutic hypothermia
- Procedure
- Lead sponsor
- University of Texas Southwestern Medical Center
- Other
- Eligibility
- 36 Weeks and older
- Enrollment
- 460 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2029
- U.S. locations
- 1
- States / cities
- Dallas, Texas
- Conditions
- Mild Traumatic Brain Injury
- Interventions
- TecTraum device
- Device
- Lead sponsor
- TecTraum Inc.
- Industry
- Eligibility
- 12 Years to 21 Years
- Enrollment
- 174 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2022
- U.S. locations
- 5
- States / cities
- Ann Arbor, Michigan • Akron, Ohio • Boardman, Ohio + 2 more
- Conditions
- Stroke, Acute
- Interventions
- Zoll- Coolgaurd 3000
- Device
- Lead sponsor
- Emory University
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012
- U.S. locations
- 1
- States / cities
- Atlanta, Georgia
- Conditions
- Cerebral Hemorrhage, Hypothermia
- Interventions
- mild induced hypothermia, Normal Temperature
- Procedure · Other
- Lead sponsor
- Thomas Jefferson University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2012
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Tinnitus, Tinnitus, Subjective
- Interventions
- Cold pack-delivered mild therapeutic hypothermia, Sham (No Treatment)
- Device
- Lead sponsor
- Restorear Devices LLC
- Industry
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 80 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Bozeman, Montana
- Conditions
- Cardiac Arrest
- Interventions
- mild hypothermia
- Device
- Lead sponsor
- Medivance, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 64 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2004 – 2007
- U.S. locations
- 6
- States / cities
- Tucson, Arizona • Denver, Colorado • Baltimore, Maryland + 3 more
- Conditions
- Out-of-hospital Cardiac Arrest
- Interventions
- Rapid infusion of 2 liters of 4oC normal saline, Rapid infusion of cold normal saline
- Other · Drug
- Lead sponsor
- University of Washington
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 1,359 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2013
- U.S. locations
- 1
- States / cities
- Seattle, Washington