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Showing 1–24 of 122 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: myofascial therapy Clear all
Not yet recruiting Not applicable Interventional

Ischemic Compression and Low-Level Laser Therapy for Myofascial Low Back Pain

NCT07832422
View directory record Official record
Conditions
Low Back Pain, Myofascial Pain Syndromes
Interventions
Ischemic Compression, Low-Level Laser Therapy, Exercise Program, Sham Low-Level Laser Therapy
Other · Device
Lead sponsor
Nova Southeastern University
Other
Eligibility
18 Years to 80 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Sep 23, 2026, 5:35 AM EDT
Not listed Phase 2 Interventional

How Does Manual Therapy Improve Low Back Pain for Soldiers?

NCT00394264
View directory record Official record
Conditions
Low Back Pain
Interventions
Soft Tissue, Myofascial release, Counterstrain, Muscle energy, Sacro-iliac articulation, High-velocity, low amplitude
Procedure
Lead sponsor
University of North Texas Health Science Center
Other
Eligibility
17 Years to 35 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Fort Lewis, Washington
Source: ClinicalTrials.gov public record
Updated Oct 30, 2006 · Synced Sep 23, 2026, 5:35 AM EDT
Completed Not applicable Interventional

Physical Therapy in Women With Interstitial Cystitis

NCT00733603
View directory record Official record
Conditions
Interstitial Cystitis, Painful Bladder Syndrome
Interventions
Global Therapeutic Massages (GTM), Myofascial Tissue Manipulation (MTM)
Other
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years and older · Female only
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
10
States / cities
San Diego, California • Stanford, California • Maywood, Illinois + 7 more
Source: ClinicalTrials.gov public record
Updated Mar 21, 2021 · Synced Sep 23, 2026, 5:35 AM EDT
Completed Not applicable Interventional

Comparison of Three Treatments for Lower Extremity Apophysitis

NCT01826071
View directory record Official record
Conditions
Osgood-Schlatter Syndrome (OSS), Sinding-Larson and Johansson Syndrome (SLJ), Sever's Disease, Apophysitis
Interventions
Static Stretch, Active Elongation
Other
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
8 Years to 17 Years
Enrollment
129 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 9, 2025 · Synced Sep 23, 2026, 5:35 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Ultrasonographic Evaluation of Osteopathic Manipulation for Thoracic Outlet Syndrome

NCT06273969
View directory record Official record
Conditions
Thoracic Outlet Syndrome
Interventions
Osteopathic Manipulative Treatment (OMT)
Other
Lead sponsor
A.T. Still University of Health Sciences
Other
Eligibility
18 Years to 65 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Kirksville, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 23, 2024 · Synced Sep 23, 2026, 5:35 AM EDT
Completed Not applicable Interventional

Effects of Osteopathic Manipulative Therapy on Arrhythmias

NCT04004741
View directory record Official record
Conditions
Cardiac Arrhythmia
Interventions
Osteopathic Manipulative Treatment, Light Touch Therapy
Procedure
Lead sponsor
New York Institute of Technology
Other
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Glen Head, New York
Source: ClinicalTrials.gov public record
Updated Apr 5, 2023 · Synced Sep 23, 2026, 5:35 AM EDT
Recruiting Not applicable Interventional

Osteopathic Manipulative Therapy Effects on Post-Acute Sequelae of COVID-19 (PASC) or Long COVID

NCT06883513
View directory record Official record
Conditions
Long-COVID, PASC, Long COVID Syndrome
Interventions
Osteopathic Manipulative Therapy Long-COVID protocol, Osteopathic Manipulative Therapy NOT Long-COVID treatment protocol
Other
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Mar 18, 2025 · Synced Sep 23, 2026, 5:35 AM EDT
Completed Not applicable Interventional

Myofascial Massage for Pain and Immobility Following Breast Cancer Surgery

NCT04233385
View directory record Official record
Conditions
Breast Cancer, Mastectomy; Lymphedema, Pain, Shoulder, Mobility Limitation
Interventions
Myofascial Massage, Light Touch
Other
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 7, 2025 · Synced Sep 23, 2026, 5:35 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Massage on Pain Levels, Range of Motion, and Muscle Strength in Unilateral Lower Limb Amputees

NCT03389334
View directory record Official record
Conditions
Amputation
Interventions
massage
Other
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Sep 24, 2018 · Synced Sep 23, 2026, 5:35 AM EDT
Terminated Not applicable Interventional

OMT of Somatic Dysfunction and Chronic Low Back Pain in Patients With Type 2 Diabetes Mellitus

NCT02054650
View directory record Official record
Conditions
Chronic Low Back Pain, Type 2 Diabetes Mellitus
Interventions
Osteopathic Manual Treatment (OMT), Sham OMT
Other
Lead sponsor
University of North Texas Health Science Center
Other
Eligibility
18 Years to 79 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated May 25, 2016 · Synced Sep 23, 2026, 5:35 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Optical Measurements of the Skin Surface to Infer Distinctions in Myofascial Tissue Stiffness

NCT06390085
View directory record Official record
Conditions
Tissue Pain
Interventions
Soft tissue manipulation
Other
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 75 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 12, 2026 · Synced Sep 23, 2026, 5:35 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Manual Physical Therapy During Pregnancy on Post Partum Perineal Trauma and Pain

NCT04660708
View directory record Official record
Conditions
Pregnancy Related, Delivery; Injury, Maternal, Pelvic Floor Disorders
Interventions
manual physical therapy
Behavioral
Lead sponsor
University of Wisconsin, Milwaukee
Other
Eligibility
18 Years and older · Female only
Enrollment
105 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Hales Corners, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 16, 2022 · Synced Sep 23, 2026, 5:35 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

OMT to Improve Feeding After Hypothermia

NCT03380013
View directory record Official record
Conditions
Neonatal Encephalopathy, Feeding; Difficult, Newborn
Interventions
Osteopathic Manipulative Treatment (OMT)
Procedure
Lead sponsor
MaineHealth
Other
Eligibility
37 Weeks and older
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Portland, Maine
Source: ClinicalTrials.gov public record
Updated May 30, 2019 · Synced Sep 23, 2026, 5:35 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Botulinum Toxin Type A (Botox) for the Treatment of Cervical Dystonia and Upper Thoracic Muscular Pain

NCT00178945
View directory record Official record
Conditions
Refractory Cervicothoracic Myofascial Pain Syndrome (CMPS), Cervical Dystonia
Interventions
Botulinum Toxin Type A
Drug
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2006
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 31, 2016 · Synced Sep 23, 2026, 5:35 AM EDT
Not listed Not applicable Interventional

Effect of Osteopathic Manipulative Medicine on Constipation in Parkinson's Disease

NCT02344485
View directory record Official record
Conditions
Parkinson's Disease, Constipation
Interventions
OMM treatment
Procedure
Lead sponsor
New York Institute of Technology
Other
Eligibility
40 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2024
U.S. locations
1
States / cities
Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated Nov 12, 2023 · Synced Sep 23, 2026, 5:35 AM EDT
Completed Not applicable Interventional Results available

Randomized Controlled Trial of CES for Fibromyalgia

NCT04115033
View directory record Official record
Conditions
Fibromyalgia
Interventions
Alpha-stim
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
20 Years to 60 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Decatur, Georgia
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Sep 23, 2026, 5:35 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Objective Kinematic Correlates of Palpatory Diagnosis

NCT00728247
View directory record Official record
Conditions
Cervical Spine
Interventions
Manual Therapy Techniques
Procedure
Lead sponsor
Michigan State University
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
East Lansing, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 19, 2010 · Synced Sep 23, 2026, 5:35 AM EDT
Active, not recruiting Phase 2 Interventional

Bladder Directed vs. Pelvic Floor Therapy in IC/BPS

NCT02870738
View directory record Official record
Conditions
Cystitis, Interstitial, Painful Bladder Syndrome
Interventions
Pelvic Floor Physical Therapy, Bladder Instillations
Procedure · Drug
Lead sponsor
Corewell Health East
Other
Eligibility
18 Years to 85 Years · Female only
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2027
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Sep 23, 2026, 5:35 AM EDT
Recruiting Not applicable Interventional

The Effect of Cupping on Spasticity and Function of the Lower Extremity During Rehabilitation After Stroke

NCT06653855
View directory record Official record
Conditions
Stroke Gait Rehabilitation
Interventions
Dry Static Cupping, Placebo cupping, Standard physical therapy treatment
Other
Lead sponsor
Scott Getsoian
Industry
Eligibility
30 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Joliet, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 12, 2024 · Synced Sep 23, 2026, 5:35 AM EDT
Not listed Not applicable Interventional

Fascial Scar Mobilization Techniques in Treating Chronic Caesarian Section Scar Pain

NCT02836626
View directory record Official record
Conditions
Cesarean Section, Cicatrix, Tissue Adhesions
Interventions
deep fascial mobilization, superficial fascial mobilization
Procedure
Lead sponsor
Rocky Mountain University of Health Professions
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
3
States / cities
Manchester, New Hampshire • McLean, Virginia • Lynnwood, Washington
Source: ClinicalTrials.gov public record
Updated Apr 10, 2017 · Synced Sep 23, 2026, 5:35 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Pedal Pump and Leg Lymphedema

NCT06235463
View directory record Official record
Conditions
Lymphedema
Interventions
Osteopathic Pedal Pump, Light Touch Treatment
Other
Lead sponsor
Rowan University
Other
Eligibility
55 Years to 100 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Stratford, New Jersey
Source: ClinicalTrials.gov public record
Updated Nov 17, 2024 · Synced Sep 23, 2026, 5:35 AM EDT
Completed Not applicable Interventional

The Role of Osteopathic Manipulation in the the Management of Post-traumatic Migraine

NCT03588364
View directory record Official record
Conditions
Migraine Disorders, Post-Traumatic Headache
Interventions
Osteopathic Manipulation
Other
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jun 11, 2019 · Synced Sep 23, 2026, 5:35 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Trigger Point Dry Needling Practice in Colorado: Practitioner and Patient

NCT04040218
View directory record Official record
Conditions
Dry Needling, Harm
Interventions
Dry Needling
Procedure
Lead sponsor
Regis University
Other
Eligibility
18 Years and older
Enrollment
2,607 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 30, 2019 · Synced Sep 23, 2026, 5:35 AM EDT
Terminated Phase 4 Interventional Results available

Buprenorphine as a Treatment in Opiate Dependent Pain Patients

NCT00552578
View directory record Official record
Conditions
Opiate Addiction, Refractory Pain
Interventions
buprenorphine/naloxone
Drug
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Feb 16, 2011 · Synced Sep 23, 2026, 5:35 AM EDT