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ClinicalTrials.gov public records Last synced Oct 6, 2026, 10:06 AM EDT

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Showing 1–24 of 215 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: near infrared spectroscopy (NIRS) Clear all
Completed No phase listed Observational

Accuracy of TCOM vs NIRS in Predicting Wound Outcomes in Patients Treated With or Without Revascularization

NCT04223089
View directory record Official record
Conditions
Wound Heal
Interventions
Near Infrared Spectroscopy
Diagnostic Test
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years to 85 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated May 10, 2023 · Synced Oct 6, 2026, 10:06 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Brain Oxygenation and Hemodynamics During Sleep in Obstructive Sleep Apnea Sufferers

NCT00591591
View directory record Official record
Conditions
Obstructive Sleep Apnea Syndrome
Interventions
OxiplexTS
Device
Lead sponsor
ISS, Inc.
Industry
Eligibility
21 Years to 55 Years
Enrollment
309 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
4
States / cities
Orange, California • Stanford, California • Chicago, Illinois + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 16, 2011 · Synced Oct 6, 2026, 10:06 AM EDT
Terminated Not applicable Interventional Results available

The Vascular Biology of Dipyridamole in Peripheral Arterial Disease (PAD)

NCT00906035
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Dipyridamole 200mg and Aspirin 25mg bid:, Dipyridamole 200 mg bid, Aspirin 25 mg bid
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 79 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2010
U.S. locations
3
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 5, 2017 · Synced Oct 6, 2026, 10:06 AM EDT
Completed No phase listed Observational

Pilot Study of the Feasibility of Multicenter NIRS Data Collection and Interventions for Desaturation in Cardiac Surgery

NCT01765504
View directory record Official record
Conditions
Cardiac Disease
Interventions
Not listed
Lead sponsor
Johns Hopkins University
Other
Eligibility
50 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 22, 2017 · Synced Oct 6, 2026, 10:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Neural Mechanisms of Split-belt Treadmill Adaptation in People With Multiple Sclerosis

NCT05878873
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Split-belt Treadmill, Transcutaneous Electrical Nerve Stimulation (TENS)
Behavioral · Device
Lead sponsor
Colorado State University
Other
Eligibility
18 Years to 86 Years
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 3, 2025 · Synced Oct 6, 2026, 10:06 AM EDT
Completed Not applicable Interventional

MGH Trauma-related Nightmares SDI Study

NCT05195684
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
imaginal probe
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 60 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 6, 2022 · Synced Oct 6, 2026, 10:06 AM EDT
Completed Not applicable Interventional

Assessing the Feasibility of a Novel Non-Invasive Sensor for Guiding Wounded Warrior Rehabilitation

NCT02887755
View directory record Official record
Conditions
Rehabilitation Post-amputation
Interventions
Near-Infrared Spectroscopy (NIRS) Sensor
Device
Lead sponsor
Henry M. Jackson Foundation for the Advancement of Military Medicine
Other
Eligibility
18 Years to 45 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 2, 2018 · Synced Oct 6, 2026, 10:06 AM EDT
Terminated Not applicable Interventional

Descriptive Analysis of Near Infrared Spectroscopy in Critically Ill and Injured Pediatric and Neonatal Patients

NCT02950181
View directory record Official record
Conditions
Stroke, Diabetic Ketoacidosis, Increased Intracranial Pressures, Altered Mental Status
Interventions
NIRS
Device
Lead sponsor
Arkansas Children's Hospital Research Institute
Other
Eligibility
1 Day to 21 Years
Enrollment
299 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated May 28, 2020 · Synced Oct 6, 2026, 10:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Arm Compression on Muscle Oxygen Saturation

NCT05037071
View directory record Official record
Conditions
Muscle; Fatigue, Heart
Interventions
Upper body graduated compression sleeve
Device
Lead sponsor
New York Institute of Technology
Other
Eligibility
18 Years to 35 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated Jan 31, 2022 · Synced Oct 6, 2026, 10:06 AM EDT
Not yet recruiting Not applicable Interventional

Measuring Pelvic Floor Muscle Fitness Before and After Treatment

NCT07605598
View directory record Official record
Conditions
Myofacial Pain, Pelvic Pain, Myofascial Pelvic Pain, Chronic Pelvic Pain
Interventions
Near Infrared Imaging
Diagnostic Test
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 26, 2026 · Synced Oct 6, 2026, 10:06 AM EDT
Withdrawn No phase listed Observational

Analysis of Cerebral Perfusion Using Head Ultrasound and Multisource Detector Near Infrared Spectroscopy (NIRS) Imaging

NCT01082536
View directory record Official record
Conditions
Congenital Heart Disease
Interventions
Not listed
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
Up to 2 Months
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 31, 2019 · Synced Oct 6, 2026, 10:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Use of Near Infrared Spectroscopy to Measure Intracranial ScvO2

NCT01746576
View directory record Official record
Conditions
Healthy
Interventions
Use of impedance threshold device during spontaneous ventilation
Other
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 16, 2014 · Synced Oct 6, 2026, 10:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cerebral Oxygenation in Total Hip Arthroplasty Patients

NCT02325154
View directory record Official record
Conditions
Cerebral Oxygen Desaturation, Post-operative Delirium
Interventions
Cerebral Oximeter
Device
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 27, 2024 · Synced Oct 6, 2026, 10:06 AM EDT
Withdrawn Not applicable Interventional

Atherosclerotic Coronary Vulnerable Plaque: Correlation With Coronary Artery Calcium

NCT01830062
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
NIRS, CACS
Other
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2021
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jul 2, 2021 · Synced Oct 6, 2026, 10:06 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Comparison of Normal Readings and Repeatability Across Skin Colors

NCT01326819
View directory record Official record
Conditions
Near Infrared Spectroscopy
Interventions
Not listed
Lead sponsor
Nonin Medical, Inc
Industry
Eligibility
18 Years and older
Enrollment
231 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated May 13, 2013 · Synced Oct 6, 2026, 10:06 AM EDT
Recruiting No phase listed Observational

Can Near-Infrared Spectroscopy (NIRS) or Intramuscular Glucose Levels Detect Impaired Leg Compartment' Perfusion?

NCT06512870
View directory record Official record
Conditions
Compartment Syndromes
Interventions
Near infrared spectroscopy (NIRS)
Diagnostic Test
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 11, 2025 · Synced Oct 6, 2026, 10:06 AM EDT
Completed Not applicable Interventional

DCS Study in Extremely Premature Newborns

NCT04367181
View directory record Official record
Conditions
Premature Birth, Extremely Low Birth Weight, Infant, Small for Gestational Age, Intracerebral Hemorrhage
Interventions
Diffuse Correlation Spectroscopy (DCS), Amplitude Integrated Electroencephalography (aEEG)
Device
Lead sponsor
Maria Angela Franceschini
Other
Eligibility
0 Hours to 72 Hours
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 17, 2025 · Synced Oct 6, 2026, 10:06 AM EDT
Terminated Not applicable Interventional

Near Infrared Spectroscopy (NIRS) for Heart Failure Assessment.

NCT01577810
View directory record Official record
Conditions
Cardiac Failure
Interventions
Near Infrared Spectroscopy
Device
Lead sponsor
Phoenix Children's Hospital
Other
Eligibility
1 Day to 18 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Nov 24, 2025 · Synced Oct 6, 2026, 10:06 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

NIRS Monitoring in the NICU and AKI

NCT07222722
View directory record Official record
Conditions
Acute Kidney Injury (AKI), Postnatal AKI
Interventions
NIRS Monitoring
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
24 Weeks to 30 Weeks
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 30, 2025 · Synced Oct 6, 2026, 10:06 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Non-invasive Measurement of Cerebrovascular Reactivity After Traumatic Brain Injury

NCT02990078
View directory record Official record
Conditions
TBI
Interventions
Sildenafil citrate, Functional Near Infared Spectroscopy, Hypercapnia Challenge
Drug · Device · Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 13, 2022 · Synced Oct 6, 2026, 10:06 AM EDT
Terminated No phase listed Observational

NIRS Monitoring in the Ambulatory Single Ventricle Patient

NCT00166218
View directory record Official record
Conditions
Ambulatory Children With Single Ventricle
Interventions
near-infrared spectroscopy
Device
Lead sponsor
Emory University
Other
Eligibility
Not listed
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Nov 27, 2013 · Synced Oct 6, 2026, 10:06 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Non-Invasive Assessment of Wound Healing With Optical Methods

NCT00578604
View directory record Official record
Conditions
Diabetic Foot Ulcers
Interventions
diffuse near infrared spectroscopy measurements
Device
Lead sponsor
Drexel University College of Medicine
Other
Eligibility
18 Years to 65 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2014
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 30, 2017 · Synced Oct 6, 2026, 10:06 AM EDT
Terminated Not applicable Interventional

Detection of Area of Ischemia in Patients With Subacute Stroke Via a Hybrid EEG-fNIRS Brain-computer Interface

NCT03034902
View directory record Official record
Conditions
Stroke
Interventions
Combined EEG and fNIRS
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 27, 2022 · Synced Oct 6, 2026, 10:06 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Detection of Hemodynamic Changes in TBI Population With Functional Near Infrared Spectroscopy

NCT01797549
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Not listed
Lead sponsor
Uniformed Services University of the Health Sciences
Federal
Eligibility
18 Years to 60 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Rockville, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 17, 2019 · Synced Oct 6, 2026, 10:06 AM EDT