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Showing 73–96 of 110 matching trials from the live ClinicalTrials.gov search.
Conditions
Pain Management
Interventions
Bupivacaine, Dexamethasone
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Birmingham, Alabama
Active, not recruiting Early Phase 1 Interventional Accepts healthy volunteers

Use of Allograft Adipose Matrix for Small Joint Arthritis of the Hand

NCT05747469
Conditions
Osteoarthritis Hand
Interventions
local anaesthetic injection, Human Adipose Allograft
Drug · Procedure
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Terminated Phase 4 Interventional Results available

A Study of Loco-Regional Liposomal Bupivacaine Injection

NCT05992896
Conditions
Peripheral Arterial Disease
Interventions
Bupivacaine liposome, Placebo
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Eau Claire, Wisconsin
Conditions
Glioblastoma, IDH-wildtype, Glioblastoma, Glioblastoma Multiforme of Brain, Astrocytoma, Malignant, Brain Neoplasms, Brain Neoplasms, Adult, Malignant, Brain Neoplasms, Adult, Recurrent Adult Brain Tumor, Recurrent Glioblastoma
Interventions
Awake mapping under local anesthesia, Asleep mapping under general anesthesia, Resection under general anesthesia without mapping
Procedure
Lead sponsor
Erasmus Medical Center
Other
Eligibility
Up to 90 Years
Enrollment
225 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
2
States / cities
San Francisco, California • Boston, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers

Infrared Thermography for Assessment of Caudal Block in Children

NCT02907957
Conditions
Anesthesia, Conduction
Interventions
FLIR ONE, Regional Anesthesia - Caudal Nerve Block
Device · Procedure
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
6 Months to 5 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Chicago, Illinois
Completed Not applicable Interventional Accepts healthy volunteers Results available

Nitrous Oxide for Pain Management of First Trimester Surgical Abortion

NCT02096575
Conditions
Abortion in First Trimester
Interventions
Nitrous oxide administration
Other
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years and older · Female only
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Albuquerque, New Mexico
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

Enhanced Recovery Strategies in Elective Breast Surgery

NCT03187080
Conditions
Pain, Acute, Nausea, Vomiting, Postoperative, Opioid Use, Satisfaction
Interventions
Paravertebral block procedure using either local anesthetic (0.25% bupivacaine) or sterile saline, Enhanced recovery after breast surgery (ERABS) strategies, Sham paravertebral block using saline, Paravertebral block using local anesthetic
Procedure · Other · Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older · Female only
Enrollment
113 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Madison, Wisconsin
Conditions
Obstructive Sleep Apnea (OSA)
Interventions
Pillar Palatal Implant System, Sham system
Device
Lead sponsor
Medtronic Xomed, Inc.
Industry
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
7
States / cities
Little Rock, Arkansas • Berkeley, California • Denver, Colorado + 4 more
Withdrawn Phase 4 Interventional Accepts healthy volunteers

Regional Anesthesia for Head and Neck Reconstruction

NCT04304716
Conditions
Pain, Postoperative
Interventions
Regional Anesthesia
Drug
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 90 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Jacksonville, Florida
Completed Not applicable Interventional Accepts healthy volunteers

Procedures for Improving the Mucosa Around Implants

NCT01944267
Conditions
Keratinized Mucosa, Dental Implants
Interventions
Apically positioned flap, Free Gingival Graft, apically positioned flap with Mucograft
Procedure
Lead sponsor
Tufts University
Other
Eligibility
18 Years to 99 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Total Hip Arthroplasty
Interventions
Quadratus Lumborum Block (QLB), Standard of Care
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Birmingham, Alabama
Completed Phase 4 Interventional Results available

Multimodal Pain Study in Free Flap Patients

NCT04246697
Conditions
Head and Neck Cancer, Analgesia
Interventions
Tylenol, Oxycodone, Morphine, Gabapentin, toradol, Bupivacaine
Drug
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Kansas City, Kansas
Conditions
Lower Extremity Fracture, Surgical Fracture Repair, Orthopaedic Trauma, Orthogeriatric Fractures
Interventions
Local anesthesia injections
Drug
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
50 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Baltimore, Maryland
Recruiting Phase 2Phase 3 Interventional Accepts healthy volunteers

Can PLIA Reduce Early Post-operative Pain After PAO Surgery?

NCT06519955
Conditions
Hip Dysplasia
Interventions
Ropivacaine, Epinephrine, Ketorolac, NaCl (Saline)
Combination Product
Lead sponsor
Michael C Willey
Other
Eligibility
13 Years to 50 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Caries
Interventions
Silver Diamine Fluoride, Conventional Caries Management
Device · Procedure
Lead sponsor
University of Michigan
Other
Eligibility
2 Years to 10 Years
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
2
States / cities
Ann Arbor, Michigan • Flint, Michigan
Completed Not applicable Interventional Accepts healthy volunteers Results available

Kinetic Anesthesia Device Study

NCT03344510
Conditions
Local Anaesthetic Complication, Pain
Interventions
Kinetic Anesthesia Device, Control
Device · Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Breast Cancer, Healthy, no Evidence of Disease
Interventions
Random fine need aspiration (rFNA), Mammogram
Procedure · Other
Lead sponsor
Northwestern University
Other
Eligibility
35 Years to 60 Years · Female only
Enrollment
385 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Post Surgical Respiratory Failure, Respiratory Complication
Interventions
Linshom Continuous Predictive Respiratory Monitoring
Device
Lead sponsor
Linshom Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
320 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Baltimore, Maryland
Terminated Not applicable Interventional Results available

Infrared Pupillometry During General Anesthesia to Predict Pain

NCT02058511
Conditions
Postoperative Pain, Objective Assessment of Sedation
Interventions
Anesthesia Premedication, Induction and Maintenance, Pupillometry after administration of anesthetic drugs
Drug · Procedure
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 99 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
San Francisco, California
Not listed Phase 1Phase 2 Interventional Accepts healthy volunteers

Tumescent Lidocaine Maximum Safe mg/kg Dosage

NCT00977028
Conditions
Anesthesia
Interventions
Tumescent Local Anesthesia (lidocaine, epinephrine), Liposuction
Drug · Procedure
Lead sponsor
Klein, Jeffrey A., M.D.
Individual
Eligibility
18 Years to 72 Years · Female only
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2011
U.S. locations
1
States / cities
San Juan Capistrano, California
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

The Role of Virtual Reality During Regional Anesthesia

NCT04163809
Conditions
Anxiety, Pain
Interventions
Virtual Reality with Oculus Go headset
Device
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years to 64 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2027 – 2028
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Local Anesthesia Injection Pain
Interventions
Local Anesthesia (lidocaine hydrochloride), Iontophoresis of Tetracaine and oxymetazoline
Drug
Lead sponsor
Louisiana State University Health Sciences Center in New Orleans
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
New Orleans, Louisiana
Conditions
Pain
Interventions
Marcaine 0.25 % Injectable Solution
Drug
Lead sponsor
Henry Ford Health System
Other
Eligibility
16 Years and older
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Detroit, Michigan
Conditions
Hand Injuries and Disorders
Interventions
Preoperative WALANT Educational Video, Traditional Preoperative Counseling
Behavioral
Lead sponsor
Carilion Clinic
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Roanoke, Virginia