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ClinicalTrials.gov public records Last synced Oct 5, 2026, 3:39 PM EDT

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Showing 25–43 of 43 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: noninvasive positive pressure ventilation Clear all

Conditions: Spontaneous Ventilation
Interventions: noninvasive positive pressure ventilation; Device
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Obstructive Sleep Apnea, Hypercapnia, Spinal Cord Injury
Interventions: BiPAP, BiPAP/AVAPS (Phillips Respironics); Device
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older
Enrollment: 93 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2016
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Obstructive Sleep Apnea, Chronic Obstructive Pulmonary Disease, Overlap Syndrome
Interventions: bi-level positive pressure non invasive ventilation, Oxygen gas; Device · Drug
Lead sponsor: University of California, San Diego; Other
Eligibility: 40 Years to 79 Years
Enrollment: 240 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: La Jolla, California

Conditions: Asthma
Interventions: NIPPV (PALMtop PTV), Volumetric CO2 (NM3), USCOM; Device
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 2 Years to 18 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Status Asthmaticus
Interventions: Noninvasive positive pressure ventilation; Other
Lead sponsor: Southern Illinois University; Other
Eligibility: 1 Year to 18 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: Springfield, Illinois

Conditions: Head Injury, Intracranial Pathology, Compromised Cerebral Perfusion
Interventions: ITPR; Device
Lead sponsor: Advanced Circulatory Systems; Industry
Eligibility: 18 Years and older
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 2
States / cities: Denver, Colorado • Baltimore, Maryland

Conditions: Amyotrophic Lateral Sclerosis, Motor Neuron Disease
Interventions: noninvasive positive pressure ventilation; Device
Lead sponsor: Columbia University; Other
Eligibility: 18 Years to 80 Years
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2012
U.S. locations: 1
States / cities: New York, New York

Conditions: Neonatal Resuscitation, Apnea Neonatal
Interventions: Ventilator derived positive pressure ventilation - V-PPV, T-piece resuscitator (TPR); Device
Lead sponsor: Michelle Baczynski; Other
Eligibility: 25 Weeks to 29 Weeks
Enrollment: 780 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Obstructive Sleep Apnea, Hypoxia, Insulin Resistance
Interventions: Continuous Positive Airway Pressure; Device
Lead sponsor: University of California, San Francisco; Other
Eligibility: 19 Years to 100 Years
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2024
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Amyotrophic Lateral Sclerosis (ALS), Chronic Respiratory Failure, Neuromuscular Disease Patients, Neuromuscular Disease, Respiratory Insufficiency, Respiratory Insufficiency Requiring Mechanical Ventilation, Positive Pressure Ventilation, Non-invasive Ventilation, Non-invasive Ventilation Support, Non-invasive Ventilatory Support
Interventions: Non-invasive ventilation; Device
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years and older
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 3
States / cities: Hershey, Pennsylvania • Philadelphia, Pennsylvania • Philadelphi, Pennsylvania

Conditions: Amyotrophic Lateral Sclerosis
Interventions: noninvasive positive pressure ventilation; Device
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2007
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Sleep Apnea, Age
Interventions: 1) hyperventilation via noninvasive positive pressure ventilation 2) multiple trials of episodic hypoxia; Other
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 89 Years
Enrollment: 92 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2015
U.S. locations: 1
States / cities: Detroit, Michigan

Conditions: Head Injury, Intracranial Pathology, Compromised Cerebral Perfusion
Interventions: ITPR; Device
Lead sponsor: Advanced Circulatory Systems; Industry
Eligibility: 18 Years and older
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Amyotrophic Lateral Sclerosis (ALS)
Interventions: Sleep study-guided adjustment of NIV, Standard initiation of NIV; Other
Lead sponsor: Columbia University; Other
Eligibility: 18 Years to 80 Years
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: New York, New York

Conditions: Status Asthmaticus
Interventions: NPPV plus standard of care; Other
Lead sponsor: Southern Illinois University; Other
Eligibility: 1 Year to 18 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: Springfield, Illinois

Conditions: Respiratory Distress Syndrome, Newborn, Bronchopulmonary Dysplasia
Interventions: Noninvasive neurally adjusted ventilatory assist (NIV NAVA), Nasal intermittent positive pressure ventilation (NIPPV); Other
Lead sponsor: Arkansas Children's Hospital Research Institute; Other
Eligibility: Up to 12 Months
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Little Rock, Arkansas

Conditions: Premature Birth
Interventions: Seattle-PAP, Conventional bubble nasal CPAP; Device
Lead sponsor: Seattle Children's Hospital; Other
Eligibility: Up to 30 Weeks
Enrollment: 220 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Chronic Obstructive Pulmonary Disease
Interventions: BiPAP Synchrony ventilator; Device
Lead sponsor: Philips Respironics; Industry
Eligibility: 21 Years to 85 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Hypercapnic Respiratory Failure
Interventions: Average Volume-Assured Pressure Support (AVAPS), Bilevel Positive Airway Pressure Spontaneous Timed (BIPAP S/T); Device
Lead sponsor: Northwell Health; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: New York, New York

Search by objective public record fields.

EIT Assessment of Lung Volume and Tidal Distribution: A Comparison of Non-Invasive Ventilation Devices

Home-Based Diagnosis and Management of Sleep-Related Breathing Disorders in Spinal Cord Injury

The Cardiovascular Consequences of Sleep Apnea Plus COPD (Overlap Syndrome)

Noninvasive Positive Airway Pressure in the Pediatric Emergency Department for the Treatment of Acute Asthma Exacerbations

Non Invasive Positive Pressure Ventilation in Status Asthmaticus

Effect of Intrathoracic Pressure Regulation on Decreased Cerebral Perfusion

Effect of Noninvasive Ventilation on Lung Function in Amyotrophic Lateral Sclerosis

Manual T-piece Versus Ventilator Positive Pressure Ventilation During Resuscitation of Extremely Premature Neonates

Tissue-specific Insulin Resistance in Obstructive Sleep Apnea: Role of Hypoxia

A Clinical Trial of Early Ventilation in Amyotrophic Lateral Sclerosis (EVENT ALS)

Noninvasive Ventilation in ALS Patients With Mild Respiratory Involvement

Determinants of Age Related Breathing Instability During Non-Rapid-Eye-Movement (NREM) Sleep

Effect of Intrathoracic Pressure Regulation on Decreased Cerebral Perfusion (4hour)

Polysomnography-directed Noninvasive Ventilation in Amyotrophic Lateral Sclerosis (ALS)

Early Noninvasive Positive Pressure Ventilation in Children With Status Asthmaticus

Work of Breathing During Non-invasive Ventilation in Premature Neonates

A Study to Evaluate the Efficacy of Seattle-PAP for the Respiratory Support of Premature Infants

The Use of High Frequency Oscillations With NIV in Hypercapnic COPD Participants

NIV for Hypercapnic Respiratory Failure: AVAPS vs S/T BIPAP