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Showing 1–15 of 15 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: nonoperative management Clear all
Recruiting Not applicable Interventional

Ultrasound and Photoacoustic Imaging for Enhanced Differential Diagnosis of Rectal Cancer

NCT04339374
View directory record Official record
Conditions
Rectal Cancer, Colorectal Cancer
Interventions
Photoacoustic imaging, photoacoustic microscopy, Endorectal photoacoustic imaging probe, Reader Performance
Device · Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
19 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 11, 2026 · Synced Sep 9, 2026, 2:08 AM EDT
Completed Phase 4 Interventional

Evaluation of Surgical Treatment on Pain and Disability for Chronic, Non-healing Rib Fracture

NCT00774618
View directory record Official record
Conditions
Rib Fracture
Interventions
Resection with or without plate fixation
Device
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 21, 2013 · Synced Sep 9, 2026, 2:08 AM EDT
Completed No phase listed Observational

Use of a Water Soluble Contrast-Based Protocol to Assist in the Management of Pediatric Adhesive Small Bowel Obstruction

NCT06101719
View directory record Official record
Conditions
Small Bowel Obstruction, Contrast Media Adverse Reaction
Interventions
Enteral contrast challenge
Diagnostic Test
Lead sponsor
Children's Hospital Colorado
Other
Eligibility
1 Year to 20 Years
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
9
States / cities
Phoenix, Arizona • Los Angeles, California • Oakland, California + 6 more
Source: ClinicalTrials.gov public record
Updated Aug 22, 2024 · Synced Sep 9, 2026, 2:08 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Distal Radius Fracture - Treatment Comparison

NCT01883063
View directory record Official record
Conditions
Minimally Displaced Intra-articular Distal Radius Fracture
Interventions
Surgical Treatment, Non surgical Treatment (Cast or splint)
Device
Lead sponsor
Sonoma Orthopedic Products, Inc.
Industry
Eligibility
65 Years and older
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
3
States / cities
Winfield, Illinois • Columbia, Missouri • Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Apr 13, 2015 · Synced Sep 9, 2026, 2:08 AM EDT
Completed Not applicable Interventional

Does Physical Therapy Prevent Total Knee Arthroplasty in Patients With End Stage Osteoarthritis

NCT02377102
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Physical Therapy
Procedure
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 13, 2017 · Synced Sep 9, 2026, 2:08 AM EDT
Recruiting Phase 2 Interventional

Immunologic Response to Pneumococcal Polysaccharide Vaccine in Splenic Injury Patients

NCT02232191
View directory record Official record
Conditions
Asplenia
Interventions
Pneumovax-23
Biological
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 65 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2027
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Sep 9, 2026, 2:08 AM EDT
Not yet recruiting No phase listed Observational

SnapChole: An International, Time-Bound Prospective Platform Study of Management Strategies and Outcomes in Acute Calculous Cholecystitis

NCT07568080
View directory record Official record
Conditions
Cholecystitis, Acute
Interventions
Not listed
Lead sponsor
European Society for Trauma and Emergency Surgery
Other
Eligibility
18 Years and older
Enrollment
1,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Sep 9, 2026, 2:08 AM EDT
Terminated Phase 2 Interventional Results available

Study of Adrenalectomy Versus Observation for Subclinical Hypercortisolism

NCT02001051
View directory record Official record
Conditions
Subclinical Hypercortisolism, Cushing Syndrome, Adrenal Neoplasm
Interventions
Adrenalectomy, Observation
Procedure · Other
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years to 99 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 13, 2018 · Synced Sep 9, 2026, 2:08 AM EDT
Completed Not applicable Interventional Results available

Recurrence Following Nonoperative Management of 1st Episode of Hinchey II Diverticulitis

NCT01986686
View directory record Official record
Conditions
Diverticulitis
Interventions
Colon resection
Procedure
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years to 90 Years
Enrollment
107 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Oct 17, 2017 · Synced Sep 9, 2026, 2:08 AM EDT
Terminated Phase 2 Interventional

Trial Comparing Early Laparoscopic Enterolysis Versus Nonoperative Management for High-grade SBO

NCT02692638
View directory record Official record
Conditions
Small Bowel Obstruction
Interventions
Early laparoscopic enterolysis, nonoperative management
Procedure
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 1, 2020 · Synced Sep 9, 2026, 2:08 AM EDT
Enrolling by invitation No phase listed Observational

Multicenter Prospective Cohort Study on Current Treatments of Legg-Calvé-Perthes Disease

NCT02040714
View directory record Official record
Conditions
Legg Calve Perthes Disease
Interventions
Osteotomy + Long Term Non-Weight Bearing, Osteotomy + Short Term Non-Weight Bearing, Nonoperative Observation, Multiple Epiphyseal Drilling
Procedure
Lead sponsor
Texas Scottish Rite Hospital for Children
Other
Eligibility
1 Year to 18 Years
Enrollment
1,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2032
U.S. locations
28
States / cities
Birmingham, Alabama • Los Angeles, California • San Diego, California + 23 more
Source: ClinicalTrials.gov public record
Updated May 5, 2025 · Synced Sep 9, 2026, 2:08 AM EDT
Completed Not applicable Interventional

Observation vs Embolization in Severe Splenic Injury: A Randomized Controlled Trial

NCT05008172
View directory record Official record
Conditions
Spleen Injury
Interventions
Splenic Artery Embolization
Procedure
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Mar 13, 2025 · Synced Sep 9, 2026, 2:08 AM EDT
Terminated Not applicable Interventional

RSA vs. Nonop for 3 & 4-Part Proximal Humerus Fractures

NCT03599336
View directory record Official record
Conditions
Humerus Fracture, Humerus, Shoulder Fractures, Shoulder Arthropathy Associated With Other Conditions, Arthropathy Shoulder, Shoulder Injury, Arthropathy
Interventions
Reverse Total Shoulder Arthroplasty (rTSA), Nonoperative Treatment
Procedure · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
65 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 10, 2021 · Synced Sep 9, 2026, 2:08 AM EDT
Completed No phase listed Observational

Cost Effectiveness of Nonoperative Management for Adult Spinal Deformity

NCT01880164
View directory record Official record
Conditions
Spinal Deformity
Interventions
Not listed
Lead sponsor
Shay Bess
Other
Eligibility
40 Years to 75 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
10
States / cities
Sacramento, California • San Francisco, California • Denver, Colorado + 6 more
Source: ClinicalTrials.gov public record
Updated Apr 5, 2017 · Synced Sep 9, 2026, 2:08 AM EDT
Completed Not applicable Interventional Results available

Comparing Surgery Versus Standard Physical Therapy in Treating People With a Meniscal Tear and Osteoarthritis

NCT00597012
View directory record Official record
Conditions
Osteoarthritis
Interventions
Arthroscopic partial menisectomy, Standard physical therapy, Postoperative rehabilitative physical therapy
Procedure · Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
45 Years and older
Enrollment
351 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2025
U.S. locations
7
States / cities
Chicago, Illinois • Boston, Massachusetts • Rochester, Minnesota + 4 more
Source: ClinicalTrials.gov public record
Updated May 17, 2026 · Synced Sep 9, 2026, 2:08 AM EDT