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ClinicalTrials.gov public records Last synced Nov 15, 2026, 6:55 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 217–240 of 4,558 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: obesity Clear all

Conditions: Breast Cancer, Prostate Cancer, Lung Cancer, Colon Cancer, Melanoma of Skin, Endometrial Cancer, Liver Cancer, Pancreatic Cancer, Rectal Cancer, Kidney Cancer, Other Solid Malignant Tumors
Interventions: Metformin, Coach Directed Behavioral Weight Loss, Self-control weight loss; Drug · Behavioral
Lead sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins; Other
Eligibility: 18 Years and older
Enrollment: 121 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Obesity
Interventions: low vs high glycemic index diet; Behavioral
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 18 Years to 35 Years · Male only
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2003 – 2006
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Pediatric Obesity, Type 2 Diabetes, Metabolic Syndrome
Interventions: Family Focused Lifestyle Intervention; Behavioral
Lead sponsor: Nemours Children's Clinic; Other
Eligibility: 8 Years to 11 Years
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2010
U.S. locations: 1
States / cities: Jacksonville, Florida

Conditions: Insulin Sensitivity
Interventions: Maltodextrin, Synbiotic, Sevelamer; Drug
Lead sponsor: The University of Texas Health Science Center at San Antonio; Other
Eligibility: 18 Years to 65 Years
Enrollment: 69 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2018
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Heart Failure With Preserved Ejection Fraction
Interventions: HU6, Placebo; Drug
Lead sponsor: Rivus Pharmaceuticals, Inc.; Industry
Eligibility: 40 Years and older
Enrollment: 67 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 15
States / cities: Beverly Hills, California • Torrance, California • Hialeah, Florida + 11 more

Conditions: Obesity
Interventions: Behavioral counseling and optional meal replacement program; Other
Lead sponsor: Johns Hopkins Bloomberg School of Public Health; Other
Eligibility: 18 Years and older
Enrollment: 155 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1990 – 2018
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Obesity, Obesity, Morbid, Obesity Associated Disorder, Bariatric Surgery Candidate, Fistula, Gastric, Roux-en-y Anastomosis Site, Ulcer, Gastric, Abdominal Pain, Abdominal Obesity, Complication of Surgical Procedure, Complication of Treatment, Complication,Postoperative, Weight Gain, Weight Loss, Leak, Anastomotic, Delayed Gastric Emptying Following Procedure
Interventions: Primary Obesity Endoscopic Procedures, Endoscopic Revision of Bariatric Surgical Procedures, Bariatric Surgery Procedures, Endoscopic Sleeve Gastroplasty, Trans-oral Outlet Reduction, Intragastric Balloon, Primary obesity surgery endoluminal, Restorative obesity surgery endoluminal, Argon Plasma Coagulation, Gastroplasty with Endoscopic Myotomy, Bariatric Endoscopic Antral Myotomy, Pylorus Sparing Antral Myotomy, Aspiration Therapy; Procedure · Device
Lead sponsor: Christopher C. Thompson, MD, MSc; Other
Eligibility: 18 Years to 80 Years
Enrollment: 5,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2029
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Obesity
Interventions: Not listed
Lead sponsor: University of Massachusetts, Boston; Other
Eligibility: 21 Years and older
Enrollment: 305 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Infant Body Composition and Metabolism, Metabolism, Energy Expenditure, Infant Formula, Human Milk, Breast Milk, Metabolic Flexibility
Interventions: Meal Test - Human Milk, Meal Test - Infant Formula; Other
Lead sponsor: Pennington Biomedical Research Center; Other
Eligibility: 2 Weeks to 16 Weeks
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Baton Rouge, Louisiana

Conditions: Overweight, Obesity, Chronic Kidney Disease, Type 2 Diabetes, T2D
Interventions: Tirzepatide, Placebo; Drug
Lead sponsor: Eli Lilly and Company; Industry
Eligibility: 18 Years and older
Enrollment: 134 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 10
States / cities: Northridge, California • Aurora, Colorado • Denver, Colorado + 7 more

Conditions: Bone Loss
Interventions: Bisphosphonate, Resistance Training/Bone-Loading Exercise, Placebo; Drug · Behavioral · Other
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 60 Years and older
Enrollment: 900 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2028
U.S. locations: 2
States / cities: Aurora, Colorado • Winston-Salem, North Carolina

Conditions: Diabetes, Obese
Interventions: Lipid infusion and muscle biopsies; Other
Lead sponsor: Mayo Clinic; Other
Eligibility: 21 Years to 55 Years
Enrollment: 16 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: Scottsdale, Arizona

Conditions: Obesity
Interventions: Not listed
Lead sponsor: Ethicon Endo-Surgery; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Hypertension, Diabetes Mellitus, Type 2
Interventions: telmisartan combined with hydrochlorothiazide (80/12.5 mg), valsartan combined with hydrochlorothiazide (160/12.5mg); Drug
Lead sponsor: Boehringer Ingelheim; Industry
Eligibility: 30 Years and older
Enrollment: 840 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2004
U.S. locations: 60
States / cities: Birmingham, Alabama • Huntsville, Alabama • Mobile, Alabama + 47 more

Conditions: Severe Obesity, Obesity, BMI Greater Than 30
Interventions: Tirzepatide, Standard of Care post-gastric bypass; Drug · Other
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 25 Years to 65 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Obesity
Interventions: CP-945,598 Treatment B, CP-945,598 Treatment A, Placebo; Drug
Lead sponsor: Pfizer; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 1,253 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2009
U.S. locations: 15
States / cities: Peoria, Arizona • Newport Beach, California • Miami, Florida + 12 more

Conditions: Obesity, Depression, GLP-1
Interventions: GLP-1; Drug
Lead sponsor: University of California, San Diego; Other
Eligibility: Not listed
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: San Diego, California

Conditions: Hypertension, Obesity
Interventions: Neuropeptide Y; Drug
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years to 55 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2026
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Morbid Obesity
Interventions: Not listed
Lead sponsor: Children's Hospital Medical Center, Cincinnati; Other
Eligibility: Not listed
Enrollment: 180 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2010
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Inflammation
Interventions: Cranberry, Non-Cranberry beverage; Other
Lead sponsor: Tufts University; Other
Eligibility: 30 Years to 70 Years
Enrollment: 79 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2013
U.S. locations: 2
States / cities: Boston, Massachusetts • Pullman, Washington

Conditions: Nausea
Interventions: SeaBand; Device
Lead sponsor: Florencia Ziemke; Other
Eligibility: 18 Years to 90 Years
Enrollment: 35 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Jupiter, Florida

Conditions: Type 2 Diabetes, Obesity
Interventions: Portion-controlled diet, Usual Diet; Other · Dietary Supplement
Lead sponsor: Nutrisystem, Inc.; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Overweight, Obesity
Interventions: Lifestyle Counseling; Behavioral
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years to 39 Years · Female only
Enrollment: 569 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2017
U.S. locations: 2
States / cities: East Lansing, Michigan • Columbus, Ohio

Conditions: Childhood Obesity
Interventions: weight managment program, Active Gaming; Behavioral · Other
Lead sponsor: UnitedHealth Group; Industry
Eligibility: 6 Years to 12 Years
Enrollment: 77 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2012
U.S. locations: 11
States / cities: Andover, Massachusetts • Lawrence, Massachusetts • Methuen, Massachusetts + 8 more

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Survivorship Promotion In Reducing IGF-1 Trial

Glycemic Index and CVD: a Crossover Feeding Study

A Family Based Intervention to Reduce the Risk of Type 2 Diabetes in Children

Mechanism of Microbiome-induced Insulin Resistance in Humans (Aim2)

Exploratory Ph 2A, Double-Blind, Placebo-Controlled Dose Escalation Study of Safety, Tolerability, PD, & PK of HU6 for Subjects With Obese HFpEF

Johns Hopkins Weight Management Center Patient Data

Endoscopic Metabolic and Bariatric Therapies

Pediatric Behavioral Informatics to Prevent Cancer

Studying Phenotypic Risks for Obesity and Underlying Traits in Young Infants

A Study of Tirzepatide (LY3298176) in Participants With Overweight or Obesity and Chronic Kidney Disease With or Without Type 2 Diabetes

Bone, Exercise, Alendronate, and Caloric Restriction

PGC-1 and Mitochondrial Dysfunction in Diabetes

Metabolic Factors of Outcomes From Gastric Bypass Surgery

SMOOTH - Blood Pressure Control in Diabetic/Obese Patients

GLP-1 Receptor Agonists Post-Bariatric Surgery (GRABS) Pilot Trial

Effect of 2-year Administration of CP-945,598 on Weight Loss Efficacy and Safety.

GLP-1 Medicines and Mental Health Changes

Sympathetic Transduction in Obesity-associated Hypertension (OB-HTN)

Follow-up of Adolescent Bariatric Surgery

Effect of Chronic Consumption of a Cranberry Beverage on Inflammation and Oxidative Stress

Acupressure Wristbands for GLP-1RA Related Nausea

Blood Glucose Stability and Variability on Two Diets

Mothers in Motion Program to Prevent Weight Gain in WIC Mothers (MIM)

Evaluation of a Commercial Gaming Impact in a Childhood Obesity Intervention