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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: obesity Clear all
Completed Not applicable Interventional Results available

Testing Intervention Strategies for Addressing Obesity and Binge Eating

NCT04771455
View directory record Official record
Conditions
Obesity, Binge Eating
Interventions
Behavioral weight loss, Intervention component: Decrease overvaluation of weight and shape, Intervention component: Decrease unhealthy weight control practices, Intervention component: Decrease negative affect
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Sep 25, 2026, 11:57 AM EDT
Completed Phase 1 Interventional

Comparing the Extent to Which Maridebart Cafraglutide (AMG 133) is Made Available in the Body When Administered Using Two Subcutaneous (SC) Presentations

NCT07226778
View directory record Official record
Conditions
Overweight, Obesity
Interventions
Maridebart Cafraglutide
Drug
Lead sponsor
Amgen
Industry
Eligibility
18 Years to 60 Years
Enrollment
348 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
4
States / cities
Anaheim, California • Daytona Beach, Florida • Dallas, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 16, 2026 · Synced Sep 25, 2026, 11:57 AM EDT
Completed No phase listed Observational

Effect of Continuous Positive Airway Pressure (CPAP) on Lower Esophageal Sphincter Pressure in Morbidly Obese Patients

NCT01099735
View directory record Official record
Conditions
Sleep Apnea, Gastroesophageal Reflux Disease
Interventions
Not listed
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 29, 2019 · Synced Sep 25, 2026, 11:57 AM EDT
Active, not recruiting Not applicable Interventional

Timing Intervention of Morning Versus Evening Exercise

NCT05153252
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Morning Exercise, Evening Exercise
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 55 Years
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Sep 25, 2026, 11:57 AM EDT
Completed Not applicable Interventional Results available

Daily Weight Feedback for Wheelchair Users to Promote Weight Loss

NCT03264248
View directory record Official record
Conditions
Overweight and Obesity, Depression
Interventions
E-Scale
Device
Lead sponsor
Jonathan Pearlman
Other
Eligibility
18 Years to 80 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 20, 2019 · Synced Sep 25, 2026, 11:57 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

The Effect of Bariatric Surgery on Metabolism, the Metabolome and Microbiome in Patients With Type 2 Diabetes

NCT02762708
View directory record Official record
Conditions
Type 2 Diabetes Mellitus, Obesity
Interventions
Roux-en-Y Gastric Bypass (RYGB), Caloric Restriction, Exendin-9,39, Normal Saline
Procedure · Behavioral · Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
20 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 2, 2022 · Synced Sep 25, 2026, 11:57 AM EDT
Enrolling by invitation No phase listed Observational

Group Medical Appointments for Intensive Lifestyle Treatment for Obesity in Cleveland Clinic Primary Care Practices

NCT07268417
View directory record Official record
Conditions
Obesity & Overweight
Interventions
ACTIVATE OC
Other
Lead sponsor
Anita Misra-Hebert
Other
Eligibility
20 Years to 75 Years
Enrollment
3,600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 10, 2026 · Synced Sep 25, 2026, 11:57 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Long-term Caloric Restriction and Cellular Aging Markers

NCT01256840
View directory record Official record
Conditions
Aging
Interventions
Not listed
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
71 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 12, 2017 · Synced Sep 25, 2026, 11:57 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Postprandial Nutrient Homeostasis Before and After Weight Loss Induced by Low-calorie Diet or RYGB

NCT03091725
View directory record Official record
Conditions
Obesity
Interventions
Roux-en-Y gastric bypass surgery, Low-calorie diet
Procedure · Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
25 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2026
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Sep 25, 2026, 11:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Articulated Oral Airway as an Aid to Mask Ventilation

NCT03144089
View directory record Official record
Conditions
Mask Ventilation, Airway Obstruction Upper, Airway Management
Interventions
Articulated Oral Airway, Guedel oral airway (active comparator)
Device
Lead sponsor
Ron Abrons
Other
Eligibility
18 Years to 99 Years
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jul 22, 2021 · Synced Sep 25, 2026, 11:57 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Youth-Onset Type 2 Diabetes and Heart Disease: The Young at Heart Prospective Cohort Study

NCT06730113
View directory record Official record
Conditions
Obesity, Type 2 Diabetes
Interventions
Not listed
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
12 Years to 25 Years
Enrollment
930 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2033
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 16, 2026 · Synced Sep 25, 2026, 11:57 AM EDT
Withdrawn No phase listed Observational

Use of the INAMED LAPBAND System to Reduce BMI's in Obese Renal Failure Patients

NCT00466882
View directory record Official record
Conditions
Renal Failure, Obesity
Interventions
Inamed Lap-Band System
Device
Lead sponsor
Summa Health System
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2011
U.S. locations
1
States / cities
Akron, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 29, 2018 · Synced Sep 25, 2026, 11:57 AM EDT
Completed No phase listed Observational

TODAY2 Phase 1 Immediate Post-Intervention Observational Follow-up Study

NCT01364350
View directory record Official record
Conditions
Diabetes Mellitus Type 2 in Obese
Interventions
standard of care in general clinical practice
Other
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
12 Years to 24 Years
Enrollment
550 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
16
States / cities
Los Angeles, California • Denver, Colorado • New Haven, Connecticut + 11 more
Source: ClinicalTrials.gov public record
Updated Aug 3, 2021 · Synced Sep 25, 2026, 11:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Grapefruit or Grapefruit Juice on Anthropometry, Dietary Intakes, Appetite, and Metabolic Profile in Overweight and Obese Young and Middle-Aged Adults

NCT00581074
View directory record Official record
Conditions
Obesity
Interventions
diet (grapefruit or grapefruit juice)
Behavioral
Lead sponsor
Vanderbilt University
Other
Eligibility
21 Years to 50 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 26, 2011 · Synced Sep 25, 2026, 11:57 AM EDT
Terminated No phase listed Observational

Obesity and Weight Loss on Reproductive Function

NCT00143078
View directory record Official record
Conditions
Obesity
Interventions
Not listed
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years to 40 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 15, 2015 · Synced Sep 25, 2026, 11:57 AM EDT
Active, not recruiting Not applicable Interventional

Feasibility of the Paso Program for Patients With Metabolic Dysfunction Associated Steatotic Liver Disease

NCT06854185
View directory record Official record
Conditions
Metabolic Dysfunction Associated Steatotic Liver Disease, Overweight (BMI > 25), Metabolic Syndrome
Interventions
Paso Program
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 70 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 23, 2026 · Synced Sep 25, 2026, 11:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Optimal Timing of Exercise Initiation Within a Lifestyle Weight Loss Program

NCT01985568
View directory record Official record
Conditions
Obesity
Interventions
Sequential BT, Standard BT
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 55 Years
Enrollment
170 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 27, 2023 · Synced Sep 25, 2026, 11:57 AM EDT
Completed Not applicable Interventional

Women's Health Project for Women Wanting to Lose Weight

NCT01671397
View directory record Official record
Conditions
Obesity
Interventions
Diet and exercise counseling, Diet, exercise, sleep hygiene counseling
Behavioral
Lead sponsor
Texas Tech University Health Sciences Center
Other
Eligibility
18 Years to 70 Years · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Apr 30, 2014 · Synced Sep 25, 2026, 11:57 AM EDT
Not listed Not applicable Interventional

The Surgical Treatment of Type 2 Diabetes Mellitus in Non-Morbidly Obese Patients: A Community Hospital Study

NCT01323114
View directory record Official record
Conditions
Type 2 Diabetes Mellitus
Interventions
Laparoscopic duodenal exclusion, Conventional Medical Treatment
Procedure · Other
Lead sponsor
McKenzie Health System
Other
Eligibility
20 Years to 65 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Sandusky, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 12, 2011 · Synced Sep 25, 2026, 11:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study of the Effectiveness of Breakfast Recommendations On Reducing Body Weight

NCT01781780
View directory record Official record
Conditions
Obesity, Food Habits
Interventions
General Nutrition Recommendations, Breakfast Recommendation, No Breakfast Recommendation
Behavioral
Lead sponsor
David Allison, Phd
Other
Eligibility
20 Years to 65 Years
Enrollment
309 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
4
States / cities
Birmingham, Alabama • Denver, Colorado • Boston, Massachusetts + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 18, 2014 · Synced Sep 25, 2026, 11:57 AM EDT
Completed Not applicable Interventional Results available

Effects of Rosiglitazone on the Metabolic Phenotype of Impaired Glucose Tolerance in Youth

NCT00413335
View directory record Official record
Conditions
Obesity, Impaired Glucose Tolerance, Type 2 Diabetes Mellitus
Interventions
Rosiglitazone, Placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
10 Years to 18 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 21, 2013 · Synced Sep 25, 2026, 11:57 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Discrimination and the Brain-Gut-Microbiome (BGM) Axis

NCT05120908
View directory record Official record
Conditions
Discrimination, Racial, Social Isolation, Stress
Interventions
Not listed
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
266 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 9, 2025 · Synced Sep 25, 2026, 11:57 AM EDT
Terminated No phase listed Observational

Genetics and Clinical Characteristics of Bardet-Biedl Syndrome

NCT00078091
View directory record Official record
Conditions
Bardet-Biedl Syndrome
Interventions
Not listed
Lead sponsor
National Human Genome Research Institute (NHGRI)
NIH
Eligibility
Not listed
Enrollment
194 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2016
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 3, 2019 · Synced Sep 25, 2026, 11:57 AM EDT
Active, not recruiting No phase listed Observational

Biological Sample Repository for Gastrointestinal Disorders

NCT05874726
View directory record Official record
Conditions
Obesity, Obesity, Morbid, Obesity, Primary, Gastro-Intestinal Disorder, Overweight and Obesity, Overweight, Overweight or Obesity, Diabetes Type 2, Diabetes Mellitus, Diabetes Mellitus, Type 2, Hypertension, Hyperlipidemias, Sleep Apnea, GERD, Gastroesophageal Reflux, Musculoskeletal Pain Disorder, Cancer
Interventions
Blood Collection, Urine Collection, Tissue Sample Collection
Diagnostic Test
Lead sponsor
Pichamol Jirapinyo, MD, MPH
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 1, 2025 · Synced Sep 25, 2026, 11:57 AM EDT