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ClinicalTrials.gov public records Last synced Oct 21, 2026, 5:54 AM EDT

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Showing 49–72 of 114 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: off-loading Clear all
Terminated Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Efficacy of Hydroxychloroquine Prophylaxis for Health Care Workers at High Risk for COVID-19

NCT04435808
View directory record Official record
Conditions
COVID-19
Interventions
Hydroxychloroquine
Drug
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Feb 14, 2022 · Synced Oct 21, 2026, 5:54 AM EDT
Not listed Not applicable Interventional

The Effect of Exercise on Wound Healing While Off-loading

NCT04280016
View directory record Official record
Conditions
Diabetic Foot Ulcer
Interventions
Exercise
Behavioral
Lead sponsor
Mercer University
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 25, 2021 · Synced Oct 21, 2026, 5:54 AM EDT
Completed Not applicable Interventional

tDCS and Cognitive Training in Active Duty Service Members With Mild TBI: A Pilot Study

NCT04925453
View directory record Official record
Conditions
Brain Concussion, Brain Trauma, Attention Concentration Difficulty, Brain Injuries, Brain Injuries, Traumatic, Neurocognitive Dysfunction, Attention Impaired, Memory Impairment, Mild Traumatic Brain Injury, Mild Cognitive Impairment
Interventions
active tDCS and cognitive training intervention, sham tDCS and cognitive training intervention
Combination Product
Lead sponsor
United States Naval Medical Center, San Diego
Federal
Eligibility
18 Years to 55 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Nov 12, 2025 · Synced Oct 21, 2026, 5:54 AM EDT
Recruiting Phase 4 Interventional

Effect of Amnio-Maxx on the Healing Rate of Chronic Diabetic Foot Ulcers.

NCT07209475
View directory record Official record
Conditions
Diabetic Foot Ulcer (DFU), Amnio-Maxx
Interventions
Amnio-Maxx® Dual Layer Amnion Patch, Standard of Care (Investigator Choice)
Biological · Other
Lead sponsor
Royal Biologics
Industry
Eligibility
18 Years and older
Enrollment
248 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
8
States / cities
Burbank, California • Miami, Florida • Stone Mountain, Georgia + 5 more
Source: ClinicalTrials.gov public record
Updated Oct 7, 2025 · Synced Oct 21, 2026, 5:54 AM EDT
Not yet recruiting Phase 2 Interventional

Using TropoCells(R) Autologous Platelet-Rich Fibrin (PRF) to Treat Chronic Non-Healing Wounds

NCT07318792
View directory record Official record
Conditions
Wound Chronic Draining, Wound Closure
Interventions
Platelet-rich fibrin (PRF)
Device
Lead sponsor
Estar Medical dba Medical Technologies, LTD
Industry
Eligibility
18 Years to 80 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
3
States / cities
Bradenton, Florida • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced Oct 21, 2026, 5:54 AM EDT
Recruiting Not applicable Interventional

Paper-Based and Smartphone-Based Memory Supports

NCT06444841
View directory record Official record
Conditions
Alzheimer Disease, Dementia, Mild, Mild Cognitive Impairment
Interventions
Digital - Google Calendar, Paper-based - Memory Support System
Behavioral
Lead sponsor
Baylor University
Other
Eligibility
50 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
3
States / cities
Austin, Texas • Temple, Texas • Waco, Texas
Source: ClinicalTrials.gov public record
Updated Jul 9, 2024 · Synced Oct 21, 2026, 5:54 AM EDT
Terminated Not applicable Interventional

NEOX® CORD 1K vs Standard of Care in Non-healing Diabetic Foot Ulcers

NCT02166294
View directory record Official record
Conditions
Foot Ulcer, Diabetic
Interventions
NEOX® CORD 1K, Standard of Care (Pressure Bandage)
Other · Procedure
Lead sponsor
Amniox Medical, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
3
States / cities
Tucson, Arizona • Castro Valley, California • Newnan, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 27, 2017 · Synced Oct 21, 2026, 5:54 AM EDT
Completed Not applicable Interventional Results available

Endoscopic vs. Suction Device Calibration in Sleeve Gastrectomy

NCT03939819
View directory record Official record
Conditions
Gastrectomy, Obesity
Interventions
ViSiGi® 3D suction calibration device, Esophagogastroduodenoscopy (EGD) calibration
Device
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated May 21, 2024 · Synced Oct 21, 2026, 5:54 AM EDT
Completed Early Phase 1 Interventional

Rehabilitation: Closed-Chain Exercises for Rotator Cuff Tears

NCT02750176
View directory record Official record
Conditions
Full Thickness Rotator Cuff Tear
Interventions
Closed chain exercises
Other
Lead sponsor
University of Southern California
Other
Eligibility
40 Years to 85 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 25, 2018 · Synced Oct 21, 2026, 5:54 AM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

A Comparison of TCC-EZ Using Human Amnion Allograft vs TCC-EZ and Standard Wound Care in Treating Diabetic Foot Ulcers.

NCT02344329
View directory record Official record
Conditions
Diabetic Foot Ulcers, Diabetes
Interventions
Topical wound dressing, Human Amnion Allograft, usual wound care
Device · Biological · Other
Lead sponsor
University of North Dakota
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Grand Forks, North Dakota
Source: ClinicalTrials.gov public record
Updated May 9, 2017 · Synced Oct 21, 2026, 5:54 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

A Study of the Safety, Pharmacokinetics and Antiretroviral Activity of 10-1074

NCT02511990
View directory record Official record
Conditions
Healthy, HIV
Interventions
3 mg/kg, single dose IV administration of 10-1074, 10 mg/kg, single dose IV administration of 10-1074, 30 mg/kg, single dose IV administration of 10-1074
Biological
Lead sponsor
Rockefeller University
Other
Eligibility
18 Years to 65 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 5, 2018 · Synced Oct 21, 2026, 5:54 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Evaluation of Two Heel Protection Devices to Assess Off-loading Via Pressure Mapping.

NCT07734220
View directory record Official record
Conditions
Pressure Injuries
Interventions
HeelMedix Basic & EHOB Waffle
Device
Lead sponsor
Medline Industries
Industry
Eligibility
22 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Northfield, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Oct 21, 2026, 5:54 AM EDT
Withdrawn Not applicable Interventional

Dynamic Splinting for Plantarflexion in Spastic Hemiplegia

NCT01329705
View directory record Official record
Conditions
Spastic Hemiplegia
Interventions
Ankle Dorsiflexion Dynasplint, Standard of care
Device · Other
Lead sponsor
Dynasplint Systems, Inc.
Industry
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 12, 2013 · Synced Oct 21, 2026, 5:54 AM EDT
Completed Not applicable Interventional

Clinical Study Evaluating Symphony™ Versus Standard of Care in the Treatment of Non-Healing Diabetic Foot Ulcers

NCT06035536
View directory record Official record
Conditions
Diabetic Foot, Diabetic Foot Ulcer, Foot Ulcer, Chronic Foot Ulcer
Interventions
Symphony™ plus Off-loading, Wound Dressing comprising of calcium alginate Fibracol
Device
Lead sponsor
Aroa Biosurgery Limited
Industry
Eligibility
18 Years and older
Enrollment
143 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
11
States / cities
Los Angeles, California • San Francisco, California • Miami, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Jan 28, 2026 · Synced Oct 21, 2026, 5:54 AM EDT
Recruiting Not applicable Interventional

Modified Multi-Platform Trial Assessing Multiple CAMPs and SOC vs SOC Alone in the Treatment of DFU and VLUs

NCT06560502
View directory record Official record
Conditions
Diabetic Foot Ulcer, Venous Leg Ulcer, Ulcer Foot, Leg Ulcer
Interventions
Standard of Care-DFU, AmnioCore - DFU, Amnio Quad-Core - DFU, Standard of Care-VLU, Amnio Tri-Core - VLU, Amniocore Pro +
Other
Lead sponsor
Stability Biologics
Industry
Eligibility
21 Years and older
Enrollment
324 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Circleville, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 20, 2025 · Synced Oct 21, 2026, 5:54 AM EDT
Terminated Phase 1Phase 2 Interventional Results available

Rapamycin for Prevention of Chronic Graft-Versus-Host Disease

NCT00623012
View directory record Official record
Conditions
Graft Versus Host Disease
Interventions
Rapamycin, Tacrolimus
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 3, 2017 · Synced Oct 21, 2026, 5:54 AM EDT
Completed Phase 2 Interventional

Safety and Effectiveness of the PXL Platinum 330 System for Corneal Collagen Cross-Linking in Eyes With Corneal Thinning Position

NCT04213885
View directory record Official record
Conditions
Keratoconus, Unstable, Ectasia Corneal, Bacterial Keratitis
Interventions
PXL 330 Platinum device/Riboflavin
Combination Product
Lead sponsor
Eye Specialists of Indiana
Other
Eligibility
12 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 29, 2024 · Synced Oct 21, 2026, 5:54 AM EDT
Completed Phase 1 Interventional

Bevacizumab in Multiple Phase I Combinations

NCT00543504
View directory record Official record
Conditions
Advanced Cancer
Interventions
Bevacizumab, Sorafenib, Erlotinib, Trastuzumab, Lapatinib, Sunitinib, Cetuximab
Drug
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
Not listed
Enrollment
343 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 30, 2020 · Synced Oct 21, 2026, 5:54 AM EDT
Completed Not applicable Interventional Results available

Powered Orthotic Exoskeleton Training in Stroke

NCT04241848
View directory record Official record
Conditions
Stroke
Interventions
Keeogo, Ambulation training
Device · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 89 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jun 10, 2025 · Synced Oct 21, 2026, 5:54 AM EDT
Completed Phase 1 Interventional

Safety and Pharmacokinetics of Regorafenib and Cetuximab in Combination

NCT01973868
View directory record Official record
Conditions
Neoplasms
Interventions
Regorafenib (Stivarga, BAY73-4506), Cetuximab (ERBITUX)
Drug
Lead sponsor
Bayer
Industry
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
4
States / cities
Los Angeles, California • Aurora, Colorado • St Louis, Missouri + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 9, 2019 · Synced Oct 21, 2026, 5:54 AM EDT
Completed Phase 1 Interventional Results available

Dose Escalation Study of MLN0128 in Combination With Paclitaxel, With/Without Trastuzumab, in Subjects With Advanced Solid Malignancies

NCT01351350
View directory record Official record
Conditions
Advanced Solid Malignancies, Hematologic Malignancies
Interventions
MLN0128, paclitaxel, trastuzumab
Drug
Lead sponsor
Millennium Pharmaceuticals, Inc.
Industry
Eligibility
18 Years and older
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
3
States / cities
Fort Myers, Florida • Oklahoma City, Oklahoma • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 8, 2019 · Synced Oct 21, 2026, 5:54 AM EDT
Active, not recruiting Phase 1Phase 2 Interventional

Anastrozole, Palbociclib, Trastuzumab and Pertuzumab in HR-positive, HER2-positive Metastatic Breast

NCT03304080
View directory record Official record
Conditions
Breast Neoplasms, Breast Diseases
Interventions
Anastrozole, Palbociclib, Trastuzumab, Pertuzumab
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2027
U.S. locations
5
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Oct 21, 2026, 5:54 AM EDT
Completed Phase 2 Interventional Results available

COVID-19 PrEP HCW HCQ Study

NCT04354870
View directory record Official record
Conditions
COVID-19
Interventions
Hydroxychloroquine (HCQ)
Drug
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 14, 2022 · Synced Oct 21, 2026, 5:54 AM EDT
Completed Not applicable Interventional

NuShield/Affinity for the Treatment of Neuropathic Diabetic Foot Ulcers

NCT02461641
View directory record Official record
Conditions
Foot Ulcer, Diabetic
Interventions
NuShield, Affinity, Standard of Care
Other
Lead sponsor
NuTech Medical, Inc
Industry
Eligibility
19 Years and older
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
7
States / cities
Fresno, California • Indianapolis, Indiana • Opelousas, Louisiana + 4 more
Source: ClinicalTrials.gov public record
Updated Feb 22, 2019 · Synced Oct 21, 2026, 5:54 AM EDT