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Showing 1–24 of 130 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: omega-3 supplementation Clear all
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Fish Oil (Omega 3), Immune Function, and Mood

NCT00385723
View directory record Official record
Conditions
Inflammation
Interventions
Omega 3 (Fish Oil) Supplementation, Placebo
Dietary Supplement
Lead sponsor
Ohio State University
Other
Eligibility
40 Years to 88 Years
Enrollment
138 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2011
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 19, 2012 · Synced Sep 11, 2026, 4:39 AM EDT
Completed Not applicable Interventional Results available

Fish Oil and Nonalcoholic Fatty Liver Disease (NAFLD) Study

NCT01285362
View directory record Official record
Conditions
Non-Alcoholic Fatty Liver Disease
Interventions
Fish Oil Supplementation, Placebo Supplementation
Drug
Lead sponsor
Columbia University
Other
Eligibility
12 Years to 18 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 4, 2022 · Synced Sep 11, 2026, 4:39 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Lutein/Zeaxanthin and Omega-3 Supplementation in Persons Over Age 60

NCT00121589
View directory record Official record
Conditions
Macular Degeneration
Interventions
Lutein
Drug
Lead sponsor
National Eye Institute (NEI)
NIH
Eligibility
60 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Sep 11, 2026, 4:39 AM EDT
Recruiting Not applicable Interventional

Concentration of n-3 PUFA Monohydroxylated Derivatives in Adults With Obesity After n-3 PUFA Supplementation.

NCT06991296
View directory record Official record
Conditions
Obesity
Interventions
SPM Active®
Dietary Supplement
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
45 Years to 60 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Kannapolis, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 16, 2026 · Synced Sep 11, 2026, 4:39 AM EDT
Completed Phase 1 Interventional

Omega-3 and Therapy Study for Depression

NCT01341925
View directory record Official record
Conditions
Depression
Interventions
Omega-3 Supplementation, Psychoeducational Psychotherapy (PEP), Placebo
Drug · Behavioral · Other
Lead sponsor
L. Eugene Arnold
Other
Eligibility
7 Years to 14 Years
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 7, 2016 · Synced Sep 11, 2026, 4:39 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Study of Vitamin D and Omega-3 Supplementation for Preventing Diabetes

NCT01633177
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Vitamin D3, Omega-3 fatty acid (fish oil), Vitamin D3 placebo, Fish oil placebo
Dietary Supplement · Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
50 Years and older
Enrollment
22,220 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 2, 2026 · Synced Sep 11, 2026, 4:39 AM EDT
Completed Not applicable Interventional

The Effects of Omega-3 Fatty Acids Supplementation on Endothelial Function and Inflammation

NCT01310270
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Pro-Omega, Omega 3 Fatty Acid
Dietary Supplement
Lead sponsor
University of California, San Francisco
Other
Eligibility
50 Years and older
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2018
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Nov 4, 2021 · Synced Sep 11, 2026, 4:39 AM EDT
Withdrawn Phase 1Phase 2 Interventional

Investigational Study of Oral Fish Oil in Treating Parenteral Nutrition Associated Liver Disease

NCT01191177
View directory record Official record
Conditions
Liver Disease, Short Bowel Syndrome
Interventions
Lovaza (omega-3-acid ethyl ester), Corn oil
Drug · Dietary Supplement
Lead sponsor
Boston Children's Hospital
Other
Eligibility
30 Days to 21 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 21, 2017 · Synced Sep 11, 2026, 4:39 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Impact of Vitamin D Supplementation on Cardiac Structure and Function

NCT01630213
View directory record Official record
Conditions
Cardiovascular Disease
Interventions
Vitamin D3 + fish oil/fish oil placebo, Vitamin D3 placebo + fish oil/fish oil placebo
Dietary Supplement
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
50 Years and older
Enrollment
1,025 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 5, 2022 · Synced Sep 11, 2026, 4:39 AM EDT
Completed Not applicable Interventional

The Effect of Fish Oil Supplementation on Endothelial Function, Heart Rate Variability and Intimal Media Thickness of Patients With Coronary Artery Disease

NCT00454493
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
Omacor (omega-3-acid ethyl esters)
Drug
Lead sponsor
Olive View-UCLA Education & Research Institute
Other
Eligibility
18 Years to 75 Years
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Sylmar, California
Source: ClinicalTrials.gov public record
Updated Mar 12, 2019 · Synced Sep 11, 2026, 4:39 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Heat Therapy and Omega 3 on Cardio-Metabolic Health

NCT04051034
View directory record Official record
Conditions
Hypertension
Interventions
Omega 3, Placebo
Dietary Supplement · Other
Lead sponsor
Texas Tech University
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Aug 13, 2019 · Synced Sep 11, 2026, 4:39 AM EDT
Enrolling by invitation Not applicable Interventional

Virtual Lifestyle Intervention for Weight Management and Cardiovascular Heal

NCT07572721
View directory record Official record
Conditions
Cardiovascular Risk Factor
Interventions
Multicomponent Virtual Lifestyle Intervention
Behavioral
Lead sponsor
Truemedicine Inc
Other
Eligibility
30 Years to 60 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Sep 11, 2026, 4:39 AM EDT
Terminated Phase 3 Interventional

Early Versus Delayed Enteral Feeding and Omega-3 Fatty Acid/Antioxidant Supplementation for Treating People With Acute Lung Injury or Acute Respiratory Distress Syndrome (The EDEN-Omega Study)

NCT00609180
View directory record Official record
Conditions
Respiratory Distress Syndrome, Adult
Interventions
Minimal (Trophic) Feeding, Full Feeding, Omega-3 Fatty Acids and Antioxidant Supplements, Placebo
Behavioral · Dietary Supplement
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
13 Years and older
Enrollment
272 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
41
States / cities
Fresno, California • Sacramento, California • San Francisco, California + 20 more
Source: ClinicalTrials.gov public record
Updated Apr 12, 2016 · Synced Sep 11, 2026, 4:39 AM EDT
Withdrawn No phase listed Observational

The Effect of Omega-3 Fatty Acid Supplementation on Intraocular Pressure & Ocular Surface

NCT02295358
View directory record Official record
Conditions
Open Angle Glaucoma, Ocular Hypertension
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
40 Years to 89 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 8, 2015 · Synced Sep 11, 2026, 4:39 AM EDT
Completed Not applicable Interventional

Omega-3 Supplementation for Smell Dysfunction

NCT02529332
View directory record Official record
Conditions
Sellar/Parasellar Tumor, Smell Dysfunction
Interventions
Omega-3
Dietary Supplement
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
2
States / cities
Stanford, California • Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 20, 2018 · Synced Sep 11, 2026, 4:39 AM EDT
Completed Phase 4 Interventional Results available

Omega Tots: A Randomized, Controlled Trial of Long-chain Polyunsaturated Fatty Acid Supplementation of Toddler Diets and Developmental Outcomes

NCT01576783
View directory record Official record
Conditions
Preterm Birth, Child Development
Interventions
Docosahexaenoic Acid + Arachidonic Acid (DHA+AA), Placebo
Drug · Dietary Supplement
Lead sponsor
Sarah Keim
Other
Eligibility
10 Months to 16 Months
Enrollment
377 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 28, 2021 · Synced Sep 11, 2026, 4:39 AM EDT
Completed Phase 1 Interventional

Cord Blood Plus Vitamin D and Omega 3s in T1D

NCT00873925
View directory record Official record
Conditions
Type 1 Diabetes
Interventions
Autologous UCB, Omega 3 FA, Vitamin D
Biological · Dietary Supplement
Lead sponsor
University of Florida
Other
Eligibility
1 Year to 18 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 3, 2013 · Synced Sep 11, 2026, 4:39 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Long-Chain Polyunsaturated Fatty Acid Supplementation on Toddler Cognition

NCT00982462
View directory record Official record
Conditions
Infant Development
Interventions
Docosahexaenoic acid (DHA) and arachidonic acid (ARA), Corn oil placebo
Dietary Supplement
Lead sponsor
Retina Foundation of the Southwest
Other
Eligibility
351 Days to 379 Days
Enrollment
116 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2016
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Apr 24, 2017 · Synced Sep 11, 2026, 4:39 AM EDT
Suspended Not applicable Interventional Accepts healthy volunteers

Effects of Fish Oil and Resistance Training on Muscle Mass and Function

NCT04245332
View directory record Official record
Conditions
Fat-free Masss, Muscle Strength, Neuromuscular Function
Interventions
Fish oil, Coconut oil
Dietary Supplement
Lead sponsor
Rowan University
Other
Eligibility
18 Years to 35 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Glassboro, New Jersey
Source: ClinicalTrials.gov public record
Updated Mar 9, 2021 · Synced Sep 11, 2026, 4:39 AM EDT
Terminated Not applicable Interventional

Immunonutrition Supplementation for Improved Burn Wound Healing in Older Adults

NCT04725071
View directory record Official record
Conditions
Burn Wound
Interventions
Impact Advanced Recovery, Boost High Protein
Dietary Supplement
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
55 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Nov 12, 2024 · Synced Sep 11, 2026, 4:39 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Nutrition, Body Composition, and Sleep

NCT03603041
View directory record Official record
Conditions
Sleep, Body Composition, Strength, Insulin Sensitivity, Energy Expenditure
Interventions
Whey protein, Omega-3 fatty acids
Dietary Supplement
Lead sponsor
University of Arkansas, Fayetteville
Other
Eligibility
Up to 85 Years · Female only
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Fayetteville, Arkansas
Source: ClinicalTrials.gov public record
Updated Feb 3, 2021 · Synced Sep 11, 2026, 4:39 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Omega-3 Fatty Acid Supplementation to Enhance Performance

NCT05924139
View directory record Official record
Conditions
Strength, Body Composition, Muscle Soreness
Interventions
Omega-3 fatty acid, Placebo
Dietary Supplement
Lead sponsor
Baylor University
Other
Eligibility
18 Years to 25 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Waco, Texas
Source: ClinicalTrials.gov public record
Updated Jun 28, 2023 · Synced Sep 11, 2026, 4:39 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Change in Omega 3 Index in Healthy Adults With OmeGo or a Standard Omega-3 Oil Supplement

NCT06802068
View directory record Official record
Conditions
Supplementation in Healthy Adults to Assess Impact on Omega 3 Index and Cardiometabolic Health
Interventions
whole salmon oil, Cod liver oil
Dietary Supplement
Lead sponsor
Hofseth Biocare ASA
Industry
Eligibility
40 Years to 80 Years
Enrollment
96 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
2
States / cities
Menlo Park, California • San Francisco, California
Source: ClinicalTrials.gov public record
Updated Feb 22, 2026 · Synced Sep 11, 2026, 4:39 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Omega-3-fatty Acids on Age-related Macular

NCT01258335
View directory record Official record
Conditions
Aged Macular Degeneration
Interventions
Omega 3, Olive Oil
Dietary Supplement · Other
Lead sponsor
Mid Atlantic Retina
Other
Eligibility
20 Years to 49 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 21, 2011 · Synced Sep 11, 2026, 4:39 AM EDT