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ClinicalTrials.gov public records Last synced Oct 23, 2026, 6:48 AM EDT

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Showing 265–288 of 1,549 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: open surgery Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Autoimmune Dysregulation in Pigmentary Glaucoma

NCT00280345
View directory record Official record
Conditions
Pigmentary Glaucoma, Primary Open Angle Glaucoma, Cataract
Interventions
Trabeculectomy, Trabeculectomy and cataract surgery, Cataract surgery
Procedure
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 85 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Dec 15, 2023 · Synced Oct 23, 2026, 6:48 AM EDT
Completed Not applicable Interventional Results available

The Effect of Tight Glycemic Control on Surgical Site Infection Rates in Patients Undergoing Open Heart Surgery

NCT01831154
View directory record Official record
Conditions
Diabetes, Hyperglycemia, Surgical Site Infection
Interventions
Tight Glycemic, Conventional Glycemic, Standard Glycemic
Drug
Lead sponsor
James A. Haley Veterans Administration Hospital
Federal
Eligibility
21 Years and older
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Apr 24, 2017 · Synced Oct 23, 2026, 6:48 AM EDT
Completed Not applicable Interventional

Measuring and Treating Brain Oxygen Levels in Open Heart Surgery

NCT01539382
View directory record Official record
Conditions
Cardiac Surgery
Interventions
Cerebral oxygenation intervention
Procedure
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 23, 2015 · Synced Oct 23, 2026, 6:48 AM EDT
Completed Not applicable Interventional Results available

Agili-C™ Implant Performance Evaluation

NCT03299959
View directory record Official record
Conditions
Cartilage or Osteochondral Defects in the Knee, Up to Moderate Osteoarthritis
Interventions
Agili-C implant, SSOC
Device · Procedure
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
21 Years to 75 Years
Enrollment
251 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
11
States / cities
San Diego, California • New Orleans, Louisiana • Salisbury, Maryland + 7 more
Source: ClinicalTrials.gov public record
Updated Dec 5, 2025 · Synced Oct 23, 2026, 6:48 AM EDT
Terminated Phase 4 Interventional Results available

Safety and Pharmacokinetics of N1539 in Children 2 to <17 Years of Age Following Surgery

NCT05315479
View directory record Official record
Conditions
Post Operative Pain
Interventions
N1539
Drug
Lead sponsor
Baudax Bio
Industry
Eligibility
2 Years to 16 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
3
States / cities
Sheffield, Alabama • Bakersfield, California • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Sep 13, 2023 · Synced Oct 23, 2026, 6:48 AM EDT
Enrolling by invitation No phase listed Observational

Therapeutic EUS Registry

NCT05233631
View directory record Official record
Conditions
Gastrointestinal Disease
Interventions
Therapeutic Endoscopic ultrasound
Procedure
Lead sponsor
Methodist Health System
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Nov 18, 2024 · Synced Oct 23, 2026, 6:48 AM EDT
Terminated Phase 2 Interventional Accepts healthy volunteers Results available

Effect of Topical Sulforaphane on Skin Fragility Seen in Skin Aging and With Ultraviolet Exposure

NCT03126539
View directory record Official record
Conditions
Aging
Interventions
Sulforaphane, Narrow-band Ultraviolet B exposure, 4 mm skin punch biopsy
Drug · Radiation · Procedure
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 29, 2023 · Synced Oct 23, 2026, 6:48 AM EDT
Terminated Phase 2 Interventional Results available

A Safety and Effectiveness Study of Intraspinal Gabapentin (MDT2004) for the Treatment of Chronic Pain

NCT00414466
View directory record Official record
Conditions
Chronic Intractable Pain
Interventions
Intraspinal Gabapentin
Drug
Lead sponsor
MedtronicNeuro
Industry
Eligibility
18 Years to 70 Years
Enrollment
254 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
14
States / cities
Little Rock, Arkansas • Napa, California • Sarasota, Florida + 11 more
Source: ClinicalTrials.gov public record
Updated Aug 23, 2013 · Synced Oct 23, 2026, 6:48 AM EDT
Completed No phase listed Observational

Pain and Quality of Life After Retromuscular Ventral Hernia Repair (RECOVER)

NCT04487522
View directory record Official record
Conditions
Ventral Hernia
Interventions
Open retromuscular ventral hernia repair, Laparoscopic retromuscular ventral hernia repair, Robotic-assisted retromuscular ventral hernia repair
Procedure · Device
Lead sponsor
Intuitive Surgical
Industry
Eligibility
18 Years to 89 Years
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
4
States / cities
Oakland, California • Sacramento, California • Santa Clara, California + 1 more
Source: ClinicalTrials.gov public record
Updated Nov 26, 2024 · Synced Oct 23, 2026, 6:48 AM EDT
Active, not recruiting Not applicable Interventional Results available

Apical Suspension Repair for Vault Prolapse In a Three-Arm Randomized Trial Design

NCT02676973
View directory record Official record
Conditions
Visceral Prolapse
Interventions
Open, Robotic, or Laparoscopic, Transvaginal Native Tissue Repair, Uphold™ LITE
Procedure
Lead sponsor
NICHD Pelvic Floor Disorders Network
Network
Eligibility
21 Years and older · Female only
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2026
U.S. locations
10
States / cities
Birmingham, Alabama • San Diego, California • Albuquerque, New Mexico + 6 more
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Oct 23, 2026, 6:48 AM EDT
Completed Not applicable Interventional

Evaluating Sexual Function After Vaginal Repair With Perineorrhaphy

NCT01779739
View directory record Official record
Conditions
Sexual Function
Interventions
Perineorrhaphy
Procedure
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
19 Years to 105 Years · Female only
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
2
States / cities
Birmingham, Alabama • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 22, 2018 · Synced Oct 23, 2026, 6:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Mindfulness Programs on Postoperative Pain

NCT04788329
View directory record Official record
Conditions
Post Operative Pain
Interventions
"Prepare for Surgery, Heal Faster" Program, Wim Hof Method
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 100 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 21, 2022 · Synced Oct 23, 2026, 6:48 AM EDT
Recruiting Phase 4 Interventional

Placement of Antibiotic Powder in Wounds During the Emergency Room

NCT03765567
View directory record Official record
Conditions
Open Fracture
Interventions
Vancomycin
Drug
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 89 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2028
U.S. locations
2
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 23, 2026, 6:48 AM EDT
Not listed Phase 4 Interventional

ZYNRELEF® for Postoperative Analgesia After Laparoscopic Sleeve Gastrectomy

NCT05863221
View directory record Official record
Conditions
Post Operative Pain, Acute, Bariatric Surgery Candidate, Postoperative Pain
Interventions
ZYNRELEF 200Mg-6Mg Extended-Release Solution
Drug
Lead sponsor
Dr. Yannis Raftopoulos
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Holyoke, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 18, 2023 · Synced Oct 23, 2026, 6:48 AM EDT
Active, not recruiting Not applicable Interventional

Percutaneous or Surgical Repair In Mitral Prolapse And Regurgitation for ≥60 Year-olds (PRIMARY)

NCT05051033
View directory record Official record
Conditions
Mitral Valve Regurgitation
Interventions
Mitral valve repair, Transcatheter edge-to-edge repair
Procedure · Device
Lead sponsor
Annetine Gelijns
Other
Eligibility
60 Years and older
Enrollment
450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2034
U.S. locations
29
States / cities
Los Angeles, California • San Francisco, California • Stanford, California + 19 more
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 23, 2026, 6:48 AM EDT
Completed No phase listed Observational

Intraocular Pressure During Robotic Assisted Laparoscopic Procedures Utilizing Steep Trendelenburg Positioning

NCT01261871
View directory record Official record
Conditions
Ocular Hypertension
Interventions
Not listed
Lead sponsor
United States Naval Medical Center, San Diego
Federal
Eligibility
18 Years and older · Male only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 19, 2016 · Synced Oct 23, 2026, 6:48 AM EDT
Completed Phase 3 Interventional Results available

RANGER™ Paclitaxel Coated Balloon vs Standard Balloon Angioplasty

NCT03064126
View directory record Official record
Conditions
Peripheral Artery Disease, Atherosclerosis, Artery Diseases, Peripheral, Plaque, Atherosclerotic, Occlusive Arterial Disease
Interventions
RANGER™ Paclitaxel Coated Balloon, Paclitaxel, Standard Balloon Angioplasty
Device · Drug · Procedure
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
20 Years and older
Enrollment
440 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
42
States / cities
Fairhope, Alabama • Aurora, Colorado • Stratford, Connecticut + 38 more
Source: ClinicalTrials.gov public record
Updated Oct 29, 2024 · Synced Oct 23, 2026, 6:48 AM EDT
Terminated Phase 3 Interventional Results available

Suppression Of Atrial Fibrillation With Ranolazine After Cardiac Surgery

NCT01352416
View directory record Official record
Conditions
Heart; Dysfunction Postoperative, Cardiac Surgery
Interventions
Ranolazine, Placebo
Drug
Lead sponsor
Corewell Health East
Other
Eligibility
22 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
2
States / cities
Royal Oak, Michigan • Troy, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 6, 2017 · Synced Oct 23, 2026, 6:48 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Derivation of a Clinical Prediction Rule to Identify Those With Low Back Pain Who Will Respond Favorably to Intramuscular Dry-needling

NCT06204055
View directory record Official record
Conditions
Low Back Pain
Interventions
Intramuscular Dry-Needling
Other
Lead sponsor
Whitworth University
Other
Eligibility
18 Years to 60 Years
Enrollment
85 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Spokane, Washington
Source: ClinicalTrials.gov public record
Updated Jan 12, 2024 · Synced Oct 23, 2026, 6:48 AM EDT
Completed Not applicable Interventional

Efficacy & Safety of Submucosal Endoscopic Myotomy With Mucosal Flap (SEMF) in the Treatment of Patients With Achalasia

NCT01438398
View directory record Official record
Conditions
Achalasia, Dysphagia
Interventions
Submucosal endoscopic myotomy with mucosal flap technique, Submucosal Endoscopic Mucosal Flap (SEMF) technique
Procedure
Lead sponsor
Winthrop University Hospital
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Mineola, New York
Source: ClinicalTrials.gov public record
Updated May 11, 2017 · Synced Oct 23, 2026, 6:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Dental Support Device in the Second Stage of Labor

NCT03138798
View directory record Official record
Conditions
Labor
Interventions
Laboraide TM dental support device
Device
Lead sponsor
Angela Bianco
Other
Eligibility
18 Years to 64 Years · Female only
Enrollment
348 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 11, 2018 · Synced Oct 23, 2026, 6:48 AM EDT
Completed Phase 2 Interventional Results available

Study to Evaluate ARD-101 in Adults Receiving Bariatric Surgery

NCT05215847
View directory record Official record
Conditions
Bariatric Surgery, Obesity, Weight Gain
Interventions
ARD-101
Drug
Lead sponsor
Aardvark Therapeutics, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Feb 11, 2025 · Synced Oct 23, 2026, 6:48 AM EDT
Recruiting Not applicable Interventional

Prospective Randomized Trial Comparing Longitudinal vs. Transverse A1 Pulley Release

NCT07516652
View directory record Official record
Conditions
Trigger Finger, Stenosing Tenosynovitis
Interventions
Open A1 Pulley Release
Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
Chicago, Illinois • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Oct 23, 2026, 6:48 AM EDT
Completed Not applicable Interventional Results available

A Clinical Trial to Validate Molecular Targets of Vorinostat in Patients With Aerodigestive Tract Cancer

NCT00735826
View directory record Official record
Conditions
Aerodigestive Tract Cancer, Lung Cancer, Esophageal Cancer, Head and Neck Cancer
Interventions
Vorinostat
Drug
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Oct 12, 2018 · Synced Oct 23, 2026, 6:48 AM EDT