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Showing 1–24 of 306 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: opioid education Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Perinatal Care and Medication Assisted Treatment: Carbon/Emery Counties

NCT04448015
View directory record Official record
Conditions
Opioid-use Disorder, Pregnancy Related
Interventions
Perinatal Opioid Use Disorder Education and Enhanced Perinatal Care
Other
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Price, Utah
Source: ClinicalTrials.gov public record
Updated Nov 9, 2020 · Synced Sep 2, 2026, 2:15 PM EDT
Terminated Not applicable Interventional

A Multimodal Enhanced Recovery Program in Anorectal Surgery

NCT03992079
View directory record Official record
Conditions
Colorectal Disorders, Anorectal Disorder, Patient Satisfaction, Pain, Postoperative, Opioid Use, Opioid Abuse, Opioid Dependence
Interventions
ReCOVER Enhanced Recovery Protocol
Procedure
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 24, 2020 · Synced Sep 2, 2026, 2:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pilot Study of Methadone Patient Access to Collaborative Treatment: a HEAL Initiative

NCT06513728
View directory record Official record
Conditions
Opioid Substitution Treatment Clinics, Patients, Staff
Interventions
MPACT Intervention
Other
Lead sponsor
University of Arizona
Other
Eligibility
18 Years and older
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 7, 2025 · Synced Sep 2, 2026, 2:15 PM EDT
Active, not recruiting Not applicable Interventional

Mobile Peer Support for OUD Recovery

NCT05405712
View directory record Official record
Conditions
Opioid Use Disorder
Interventions
Mobile Phone App
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years and older
Enrollment
1,300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
2
States / cities
Indianapolis, Indiana • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jan 28, 2026 · Synced Sep 2, 2026, 2:15 PM EDT
Not listed Not applicable Interventional

The Impact of a Web-Based Naloxone Intervention Under Standing Orders to Patients Prescribed Chronic Opioid Therapy

NCT03337009
View directory record Official record
Conditions
Overdose, Risk Behavior
Interventions
Naloxone Navigator (NN)
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
1,004 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated May 19, 2024 · Synced Sep 2, 2026, 2:15 PM EDT
Completed Not applicable Interventional

Employment-based Reinforcement to Motivate Drug Abstinence in the Treatment of Drug Addiction. - 2

NCT00249457
View directory record Official record
Conditions
Behavior, Addictive, Cocaine Abuse, Cocaine Dependence, Heroin Dependence, Opioid Dependence
Interventions
Contingency management
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1996 – 2006
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 29, 2017 · Synced Sep 2, 2026, 2:15 PM EDT
Enrolling by invitation Not applicable Interventional

Alternatives to Dental Opioid Prescribing After Tooth Extraction

NCT06275191
View directory record Official record
Conditions
Analgesics, Opioid, Acute Pain, Tooth Extraction, Adolescent, Acetaminophen, Ibuprofen
Interventions
Multicomponent intervention, Usual care
Behavioral · Other
Lead sponsor
Douglas Oyler
Other
Eligibility
12 Years to 25 Years
Enrollment
38,159 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Sep 2, 2026, 2:15 PM EDT
Completed Not applicable Interventional

Mindful Body Awareness With Medication Treatment for Opioid Use Disorder

NCT04082637
View directory record Official record
Conditions
Opioid-use Disorder
Interventions
Mindful Awareness in Body-oriented Therapy
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
303 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
5
States / cities
Bellingham, Washington • Port Angeles, Washington • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jan 23, 2025 · Synced Sep 2, 2026, 2:15 PM EDT
Active, not recruiting Not applicable Interventional

Patient Utilization of Opioid Destruction Bags in the Post-op Period

NCT05875857
View directory record Official record
Conditions
Opioid Use, Opioid Use, Unspecified, Patient Empowerment, Total Knee Arthoplasty, Total Hip Arthroplasty
Interventions
Opioid destruction education
Behavioral
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years to 100 Years
Enrollment
163 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Jan 28, 2026 · Synced Sep 2, 2026, 2:15 PM EDT
Not listed Not applicable Interventional

The Staying Safe Intervention

NCT03418636
View directory record Official record
Conditions
Hepatitis C, Opioid Use
Interventions
Staying Safe (Ssafe), Healthy Living
Behavioral
Lead sponsor
National Development and Research Institutes, Inc.
Other
Eligibility
18 Years to 29 Years
Enrollment
456 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 14, 2018 · Synced Sep 2, 2026, 2:15 PM EDT
Withdrawn Not applicable Interventional

Testing a Primary Care Model for the Treatment of Opioid Dependence Using Long-acting Injectable Naltrexone (Vivitrol).

NCT00675532
View directory record Official record
Conditions
Drug Dependence
Interventions
Primary Care Counseling, Cognitive-behavioral psychotherapy
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 21, 2013 · Synced Sep 2, 2026, 2:15 PM EDT
Completed No phase listed Observational

Targeting Effective Analgesia in Clinics for HIV - Patient Cohort

NCT02525731
View directory record Official record
Conditions
HIV Infection, Pain, Drug Dependence
Interventions
Not listed
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
2
States / cities
Atlanta, Georgia • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 19, 2018 · Synced Sep 2, 2026, 2:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

An Opioid Prescribing Nudge

NCT04069403
View directory record Official record
Conditions
Opioid Use, Unspecified, Prescription Drug Abuse (Not Dependent), Prescription Drug Abuse and Dependency, Health Behavior, Benzodiazepine Abuse, Benzodiazepine Dependent
Interventions
Automated Reports on prescription patterns for their patients
Other
Lead sponsor
Duke University
Other
Eligibility
Not listed
Enrollment
427 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 29, 2020 · Synced Sep 2, 2026, 2:15 PM EDT
Completed Not applicable Interventional Results available

An Initial Study of the Implementation of Digital Therapeutics for Substance Use Disorders in Primary Care

NCT04907045
View directory record Official record
Conditions
Drug Use Disorders, Illicit Drug Use, Alcohol-Related Disorders
Interventions
Health Coaching, Practice Facilitation, Standard Implementation
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
1,552 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 5, 2025 · Synced Sep 2, 2026, 2:15 PM EDT
Completed Not applicable Interventional

Adjunctive Mindfulness During Opioid Tapering for patientS With Chronic Pain (The AMOS Study)

NCT06268522
View directory record Official record
Conditions
Low Back Pain
Interventions
Mindfulness-Oriented Recovery Enhancement: (MORE) group, Psychoeducation
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Chestnut Hill, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 28, 2026 · Synced Sep 2, 2026, 2:15 PM EDT
Enrolling by invitation Not applicable Interventional

Opioid Education Ventral Hernia Repair

NCT07639281
View directory record Official record
Conditions
Ventral Hernia Repair, Opioid Consumption, Postoperative
Interventions
Opioid and Surgery Education Video, Surgery Education Video
Behavioral
Lead sponsor
Tori Dotson
Other
Eligibility
18 Years to 85 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Sep 2, 2026, 2:15 PM EDT
Recruiting Not applicable Interventional

Improving Outcomes for Early Postpartum Mothers in Outpatient MOUD Treatment

NCT07071766
View directory record Official record
Conditions
Substance Use Treatment, Perinatal Substance Use, Parenting
Interventions
Proud of Baby and Me
Behavioral
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years and older · Female only
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Sep 2, 2026, 2:15 PM EDT
Completed Not applicable Interventional

Effects of tDCS Combined With CBI on Postsurgical Pain

NCT04199780
View directory record Official record
Conditions
Total Knee Arthroplasty (Postoperative Pain), Total Hip Arthroplasty (Postoperative Pain)
Interventions
Transcranial Direct Current Stimulation, Cognitive-Behavioral (CB) intervention
Device · Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 90 Years
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Sep 2, 2026, 2:15 PM EDT
Completed Not applicable Interventional

Post-Discharge Opioid Reduction Intervention for Open, Laparoscopic, and Endoscopic Surgery

NCT03536065
View directory record Official record
Conditions
Prostate Cancer, Opioid Use
Interventions
Opioid Reduction Intervention, Current Care
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 100 Years · Male only
Enrollment
443 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 27, 2020 · Synced Sep 2, 2026, 2:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Reducing Prescription Opioid Misuse: ROPEs Pilot Trial

NCT03691948
View directory record Official record
Conditions
Knowledge, Attitudes, Practice
Interventions
Responsible Opioid Prescriber Education (ROPES), Active Comparator Control
Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 2, 2020 · Synced Sep 2, 2026, 2:15 PM EDT
Active, not recruiting Not applicable Interventional

Healthy Opioid Prescription Engagement

NCT05141266
View directory record Official record
Conditions
Opioid Misuse, Opioid-Related Disorders, Pharmacist-Patient Relations
Interventions
Patient Navigation, Standard Medication Counseling (SMC)
Behavioral · Other
Lead sponsor
Jerry Cochran
Other
Eligibility
18 Years and older
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Sep 2, 2026, 2:15 PM EDT
Recruiting No phase listed Observational

Discharge Medication Use Post-Operatively in GU Cancer Patients

NCT06795087
View directory record Official record
Conditions
Genitourinary Cancer
Interventions
Opioid Medication Disposal Education
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
684 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Sep 2, 2026, 2:15 PM EDT
Completed Not applicable Interventional

Buprenorphine and Substance Abuse Services for Prescription Opioid Dependence

NCT02496403
View directory record Official record
Conditions
Opiate Substitution Treatment
Interventions
Standard Medical Management (SMM)
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
239 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Sep 25, 2019 · Synced Sep 2, 2026, 2:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Use of a Nurse Pain Educator for Patients With Chronic Pain

NCT03044522
View directory record Official record
Conditions
Chronic Pain, Opioid Use, Nurse's Role
Interventions
Opioid Education
Other
Lead sponsor
NEMA Research, Inc.
Industry
Eligibility
18 Years and older
Enrollment
183 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
4
States / cities
Fort Myers, Florida • Plantation, Florida • Overland Park, Kansas + 1 more
Source: ClinicalTrials.gov public record
Updated Dec 10, 2017 · Synced Sep 2, 2026, 2:15 PM EDT