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Showing 1–24 of 156 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: optical measurements Clear all
Not listed Not applicable Interventional Accepts healthy volunteers

Study of New Catheter & Pressure Monitor System to Help Prevent Compartment Syndrome From Developing in the Injured Leg

NCT00681616
View directory record Official record
Conditions
Compartment Syndrome
Interventions
Compartment Monitoring System (CMS), Compartment Monitoring System with Active Fluid Removal, Compartment Monitoring System without fluid removal
Device
Lead sponsor
Twin Star Medical, Inc.
Industry
Eligibility
18 Years to 60 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
13
States / cities
Orange, California • San Francisco, California • Denver, Colorado + 9 more
Source: ClinicalTrials.gov public record
Updated Mar 3, 2009 · Synced Sep 10, 2026, 3:24 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Determine the Effect of Intraocular Pressure (IOP), Optic Nerve Imaging, Venous Congestion in Volunteers Prone Position 5 Hours

NCT00875043
View directory record Official record
Conditions
Blindness
Interventions
Not listed
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Oct 13, 2016 · Synced Sep 10, 2026, 3:24 PM EDT
Recruiting Not applicable Interventional

Collagen Cross-linking in Keratoconus

NCT03760432
View directory record Official record
Conditions
Keratoconus
Interventions
Laser Custom Corneal Collagen Cross-Linking
Procedure
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2027
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 8, 2025 · Synced Sep 10, 2026, 3:24 PM EDT
Terminated No phase listed Observational

3-Dimensional Form and Soft Tissue Biomechanics of the Breast

NCT00502814
View directory record Official record
Conditions
Breast Cancer
Interventions
3-D Optical Surface Scan, Mechanical Testing, Cutaneous Ultrasound, Breast MRI and/or CT
Procedure
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2011
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 21, 2012 · Synced Sep 10, 2026, 3:24 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Measuring the Peripheral Optical Quality of The Eye

NCT03479827
View directory record Official record
Conditions
Nearsightedness
Interventions
Monofocal Contact Lens, Bifocal Contact Lens
Device
Lead sponsor
University of Rochester
Other
Eligibility
18 Years to 60 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Aug 15, 2022 · Synced Sep 10, 2026, 3:24 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The Validation Study of Bioelectronics

NCT05397951
View directory record Official record
Conditions
Healthy, Health Behavior
Interventions
Multi-modality Noninvasive Biosensor, Oximeter, Portable Blood Pressure Monitor, Vicorder Pulse Wave Velocity Monitor
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 99 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced Sep 10, 2026, 3:24 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Dynamic Optical Coherence Tomography(D-OCT) Aging Study: A Preliminary Evaluation of Structural Differences Between Young and Aged Skin, Cellulite and Atrophic Acne Scars in Female Caucasian Subjects With Fitzpatrick Skin Types I-III Utilizing Non-invasive in Vivo D-OCT.

NCT03767400
View directory record Official record
Conditions
Skin Care
Interventions
Skin Imaging, Facial Cleanser
Device · Other
Lead sponsor
Allergan
Industry
Eligibility
18 Years to 75 Years · Female only
Enrollment
99 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Oct 30, 2019 · Synced Sep 10, 2026, 3:24 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Agreement and Precision Study of UNITY® DX and a Comparator Biometer

NCT06826599
View directory record Official record
Conditions
Normal Eyes, Abnormal Eyes
Interventions
Investigational Biometer, IOLMaster 700 Biometer
Device
Lead sponsor
Cylite Pty Ltd
Industry
Eligibility
22 Years and older
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Woburn, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 4, 2025 · Synced Sep 10, 2026, 3:24 PM EDT
Completed No phase listed Observational

Comparison of Two Biometers in Dense Cataracts

NCT07475832
View directory record Official record
Conditions
Cataract
Interventions
ARGOS biometer, IOLMaster 700
Diagnostic Test
Lead sponsor
Berkeley Eye Center
Other
Eligibility
45 Years and older
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Sugar Land, Texas
Source: ClinicalTrials.gov public record
Updated Mar 16, 2026 · Synced Sep 10, 2026, 3:24 PM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Measurement of the Distribution of Optical Properties in Adult Human Muscle

NCT00540683
View directory record Official record
Conditions
Muscle Disorder
Interventions
Diffuse Optical Spectroscopy
Device
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years to 75 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2018
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Oct 19, 2022 · Synced Sep 10, 2026, 3:24 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Effect of Lens Presentation on the Clinical Oculomotor Assessment at Near

NCT02679313
View directory record Official record
Conditions
Vision Disorders
Interventions
Phoropter
Device
Lead sponsor
State University of New York College of Optometry
Other
Eligibility
18 Years to 30 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 30, 2025 · Synced Sep 10, 2026, 3:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Visualizing Dermal Micropores With OCT

NCT04867733
View directory record Official record
Conditions
Healthy
Interventions
Micropatch (microneedle patch)
Other
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 45 Years
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated May 27, 2024 · Synced Sep 10, 2026, 3:24 PM EDT
Completed Not applicable Interventional Results available

Spectacles for Patients With Down Syndrome

NCT03367793
View directory record Official record
Conditions
Vision, Low
Interventions
Spectacles - Clinically Derived, Spectacles - Metric Technique #1 Derived, Spectacles - Metric Technique #2 Derived
Device
Lead sponsor
University of Houston
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 24, 2021 · Synced Sep 10, 2026, 3:24 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

OCT Agreement and Crossed Precision Study

NCT02050880
View directory record Official record
Conditions
Glaucoma, Retinal Disease, Corneal Disease
Interventions
Not listed
Lead sponsor
Nidek Co. LTD.
Industry
Eligibility
20 Years and older
Enrollment
119 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Santa Ana, California
Source: ClinicalTrials.gov public record
Updated Sep 28, 2014 · Synced Sep 10, 2026, 3:24 PM EDT
Completed No phase listed Observational Results available

FUnctional diagnoSIs of corONary Stenosis (FUSION)

NCT04356027
View directory record Official record
Conditions
Coronary Artery Disease, Coronary Stenosis
Interventions
ICA (Invasive Coronary Angiography), OCT, FFR, VFR Analysis
Procedure · Other
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
312 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
28
States / cities
Huntsville, Alabama • Scottsdale, Arizona • Little Rock, Arkansas + 22 more
Source: ClinicalTrials.gov public record
Updated Feb 20, 2025 · Synced Sep 10, 2026, 3:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Utility of Transdermal Optical Imaging (TOI) as a Non-invasive Measure of Hydration Status: Phase 3a for Model Development

NCT06044610
View directory record Official record
Conditions
Dehydration
Interventions
GENPOP Passive dehydration (75% reduction in fluid intake, GENPOP Ad lib fluid intake, EXERCISE without fluid replacement, EXERCISE with fluid replacement
Other
Lead sponsor
PepsiCo Global R&D
Industry
Eligibility
18 Years to 65 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
2
States / cities
Valhalla, New York • Plano, Texas
Source: ClinicalTrials.gov public record
Updated Jan 18, 2024 · Synced Sep 10, 2026, 3:24 PM EDT
Recruiting No phase listed Observational

To Study the Effects of Refractive Surgery on OCT Measurements in the Eye

NCT05856786
View directory record Official record
Conditions
Optical Coherence Tomography, Refractive Errors, Myopia
Interventions
Optical coherence tomography
Diagnostic Test
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Sep 10, 2026, 3:24 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

VisionApp - Ghosting

NCT07571538
View directory record Official record
Conditions
Diplopia, Monocular
Interventions
Proclear 1 Day Contact Lens, MyDay Contact Lens, NaturalVue Contact Lens, MiSight 1 Day Contact Lens, Investigational Contact Lens, VisionApp
Device
Lead sponsor
Indiana University
Other
Eligibility
8 Years and older
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 23, 2026 · Synced Sep 10, 2026, 3:24 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Clinical Validation of New OCT System

NCT01809704
View directory record Official record
Conditions
Subjects Presenting With Normal or With Ocular Pathology
Interventions
Not listed
Lead sponsor
Topcon Medical Systems, Inc.
Industry
Eligibility
18 Years and older
Enrollment
87 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
3
States / cities
La Jolla, California • Jamaica, New York • New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 9, 2022 · Synced Sep 10, 2026, 3:24 PM EDT
Not listed No phase listed Observational

OCT and Scaffold Embedding After NC Balloon

NCT03106961
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
Bioresorbable vascular scaffolds, OCT, non-compliant ballooning
Device
Lead sponsor
St. Francis Hospital, New York
Other
Eligibility
Not listed
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Roslyn, New York
Source: ClinicalTrials.gov public record
Updated Apr 10, 2017 · Synced Sep 10, 2026, 3:24 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Direct Comparison of SVOne Obtained Refraction to Subjective Manifest Refraction

NCT03222661
View directory record Official record
Conditions
Refractive Errors
Interventions
Refraction
Diagnostic Test
Lead sponsor
Smart Vision Labs
Industry
Eligibility
12 Years to 65 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 18, 2017 · Synced Sep 10, 2026, 3:24 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

P200TE Agreement and Precision Study

NCT05536401
View directory record Official record
Conditions
Retina Disease, Glaucoma, Normal
Interventions
P200TE, Predicate Device
Device
Lead sponsor
Optos, PLC
Industry
Eligibility
22 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 16, 2022 · Synced Sep 10, 2026, 3:24 PM EDT
Completed Not applicable Interventional Results available

Assessing Benefits of NIRAF Detection for Identifying Parathyroid Glands During Total Thyroidectomy.

NCT04281875
View directory record Official record
Conditions
Postoperative Hypoparathyroidism, Thyroid Neoplasms, Thyroid Cancer
Interventions
NIRAF Detection Technology
Device
Lead sponsor
Vanderbilt-Ingram Cancer Center
Other
Eligibility
18 Years to 99 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 16, 2024 · Synced Sep 10, 2026, 3:24 PM EDT
Completed No phase listed Observational Results available

Randomized Trial Comparing Prediction Accuracy of Two Swept Source Optical Coherence Tomography Biometers

NCT05748275
View directory record Official record
Conditions
Cataract
Interventions
Argos, IOLMaster 700
Diagnostic Test
Lead sponsor
Multack Eye Care
Other
Eligibility
50 Years to 85 Years
Enrollment
80 participants
Timeline
2021
U.S. locations
1
States / cities
Frankfort, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Sep 10, 2026, 3:24 PM EDT