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ClinicalTrials.gov public records Last synced Nov 13, 2026, 9:52 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 217–240 of 242 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: oral intake Clear all

Conditions: Smoking
Interventions: Varenicline, Placebo; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 40 Years · Male only
Enrollment: 19 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2010
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Hyponatremia, Dilutional Hyponatremia, Inappropriate ADH Syndrome
Interventions: tolvaptan, Fluid Restriction; Drug · Other
Lead sponsor: Otsuka Pharmaceutical Development & Commercialization, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 124 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2013
U.S. locations: 56
States / cities: Birmingham, Alabama • Mobile, Alabama • Azusa, California + 46 more

Conditions: Obesity
Interventions: Metformin, Dietary modification with caloric restriction, Establishment of exercise protocol; Drug · Behavioral
Lead sponsor: Nemours Children's Clinic; Other
Eligibility: 7 Years to 18 Years
Enrollment: 66 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2003 – 2011
U.S. locations: 1
States / cities: Jacksonville, Florida

Conditions: Hypertension
Interventions: fenofibrate, Placebo; Drug
Lead sponsor: Vanderbilt University; Other
Eligibility: 18 Years to 70 Years
Enrollment: 75 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2012
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Type 2 Diabetes
Interventions: Meal timing, Time restricted eating, Usual feeding pattern.; Other
Lead sponsor: Rockefeller University; Other
Eligibility: 18 Years to 75 Years
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025
U.S. locations: 1
States / cities: New York, New York

Conditions: Posterior Spine Surgery
Interventions: Spine surgery analgesic pathway, Usual Care; Other
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years to 80 Years
Enrollment: 299 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Fasting in Malignant Solid Tumors
Interventions: Short-term fasting, Modified fast, Fasting; Other
Lead sponsor: University of Southern California; Other
Eligibility: 19 Years and older
Enrollment: 47 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2025
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Tonsillectomy, Children
Interventions: Closure of the Tonsillar Fossa, Tonsillectomy with open fossa; Procedure
Lead sponsor: University of Oklahoma; Other
Eligibility: 5 Years to 10 Years
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Oklahoma City, Oklahoma

Conditions: Prostatic Neoplasms, Metastatic Castration-Resistant Prostate Cancer
Interventions: Abiraterone Acetate, Prednisone, JNJ-56021927; Drug
Lead sponsor: Aragon Pharmaceuticals, Inc.; Industry
Eligibility: 18 Years to 99 Years · Male only
Enrollment: 57 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2027
U.S. locations: 3
States / cities: Los Angeles, California • San Francisco, California • Houston, Texas

Conditions: Healthy
Interventions: Flavanol- and procyanidins-containing drink, Procyanidins-containing drink, Flavanol-containing drink; Other
Lead sponsor: University of California, Davis; Other
Eligibility: 18 Years to 70 Years
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008
U.S. locations: 1
States / cities: Davis, California

Conditions: Healthy Volunteers
Interventions: Sucralose, Aspartame, Acesulfame-Potassium, Control; Other
Lead sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); NIH
Eligibility: 6 Years and older
Enrollment: 118 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2017
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Cancer, Depression Secondary to Other Disease, Cancer Survivor
Interventions: Text-based depression screening, Usual care (UC); Behavioral
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years and older
Enrollment: 79 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Obesity
Interventions: PET scan, Oral glucose tolerance test, MRI, Psychological scales to assess attitudes and behaviors related to eating and quality of life, Caloric Restriction; Radiation · Procedure · Behavioral + 1 more
Lead sponsor: Vanderbilt University; Other
Eligibility: 18 Years to 60 Years
Enrollment: 28 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2012
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Anxiety, Pain, Surgery
Interventions: Galacto-Oligosaccharide, Maltodextrin (Placebo); Drug
Lead sponsor: Jeff Taekman, M.D.; Other
Eligibility: 21 Years to 70 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Obese Patients (BMI ≥ 30 kg/m²), Glucose Metabolism, Protein Metabolism
Interventions: Indispensable Amino Acid Oxidation, Stable Isotope Oral Glucose Tolerance Test; Procedure
Lead sponsor: University of Illinois at Urbana-Champaign; Other
Eligibility: 19 Years to 59 Years
Enrollment: 8 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Urbana, Illinois

Conditions: Healthy
Interventions: clopidogrel, placebo, omeprazole; Drug
Lead sponsor: Sanofi; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 72 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009
U.S. locations: 1
States / cities: Bridgewater, New Jersey

Conditions: Acute Unilateral Vestibulopathy (AUV)
Interventions: SENS-111 100mg, SENS-111 200mg, Placebo Oral Tablet; Drug
Lead sponsor: Sensorion; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 107 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: New York, New York

Conditions: Gestational Diabetes, Diagnoses Disease, Pregnancy in Diabetic, Glucose, High Blood
Interventions: Fasting before gestational diabetes screen, Per oral intake of food and drink; Behavioral
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Stanford, California

Conditions: Iron Deficiency Anemia
Interventions: Iron Supplement, multivitamin; Dietary Supplement
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 24 Weeks to 32 Weeks
Enrollment: 150 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Opioid-Induced Constipation (OIC)
Interventions: NKTR-118, Placebo; Drug
Lead sponsor: AstraZeneca; Industry
Eligibility: 18 Years to 84 Years
Enrollment: 302 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 90
States / cities: Birmingham, Alabama • Calera, Alabama • Glendale, Arizona + 87 more

Conditions: Atherosclerosis
Interventions: Statin therapy, Lifestyle modification; Drug · Behavioral
Lead sponsor: Emory University; Other
Eligibility: 22 Years and older
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Phenylketonuria
Interventions: saproterin dihydrochloride, Diet treatment; Drug · Other
Lead sponsor: University Hospitals Cleveland Medical Center; Other
Eligibility: 2 Years to 60 Years
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Sexual Dysfunction, Physiological
Interventions: Ospemifene, Vaginal conjugated estrogens; Drug
Lead sponsor: Emory University; Other
Eligibility: 40 Years and older · Female only
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017
U.S. locations: 4
States / cities: Atlanta, Georgia

Conditions: Obesity
Interventions: Medifast FIT! for Kids, standard recommendations for dietary intake in children, both diet plans with and without a parent dieting; Behavioral
Lead sponsor: Johns Hopkins Bloomberg School of Public Health; Other
Eligibility: 8 Years to 15 Years
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004 – 2006
U.S. locations: 1
States / cities: Baltimore, Maryland

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Endothelial Function and Autonomic Regulation After Short-term Smoking Cessation: Varenicline Versus Placebo

Effects of Tolvaptan vs Fluid Restriction in Hospitalized Subjects With Dilutional Hyponatremia

Study of Serum Markers for Cardiovascular Risk in Obese Youth and Impact of Lifestyle and Medication Intervention

The Effect of a Peroxisome Proliferator-activated Receptor (PPAR) Alpha Agonist on Cytochrome P450 (CYP) Monooxygenase Activity in Humans

The Impact of Time Restricted Eating on Type 2 Diabetes

Evaluation of Spine Surgery Analgesic Pathway

Short-Term Fasting: Impact on Toxicity

Closure Method Study Following Tonsillectomy in Children

A Study of JNJ-56021927 (ARN-509) and Abiraterone Acetate in Participants With Metastatic Castration-Resistant Prostate Cancer

Absorption and Metabolism of Dietary Cocoa Procyanidins in Humans

Metabolic Effects of Non-Nutritive Sweeteners

Text -Based Depression Screening Among Cancer Survivors

Dopamine and Insulin Resistance

Exploring the Impact of Perioperative Galacto-Oligosaccharides (GOS) on Stress, Anxiety and Cognition

Stable Isotopes- Adults With Obesity

Interaction Study of Clopidogrel 300/75 mg Given Alone or Concomitantly With Omeprazole 80 mg in Healthy Subjects

Efficacy of SENS-111 in Patients Suffering From Acute Unilateral Vestibulopathy

Fasting Versus Fed: Effect of Oral Intake Prior to the Glucose Tolerance Test in Pregnancy

Trial Comparing Iron Supplementation Versus Routine Iron Intake in Very Low Birth Weight Infants

A 12-week Extension of the Phase III Study (D3820C00004) to Assess the Effect and Safety of NKTR-118 in Patients With Non-cancer-related Pain and Opioid-induced Constipation

Accelerated Atherosclerosis in High Risk Population Groups: An Assessment by Magnetic Resonance Imaging

The Effectiveness of Kuvan in Amish PKU Patients

Ospemifene vs. Conjugated Estrogens in the Treatment of Postmenopausal Sexual Dysfunction

Efficacy of Parent-Child Dieting Plans Incorporating Medifast Meal Replacements for Weight Loss