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ClinicalTrials.gov public records Last synced Nov 12, 2026, 4:49 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 145–168 of 242 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: oral intake Clear all

Conditions: Overweight and Obesity, Eating Behavior
Interventions: Placebo, Bromocriptine-QR; Drug
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years to 35 Years
Enrollment: 55 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: High Blood Pressure, Salt; Excess, Inflammation
Interventions: Furosemide 40 mg; Drug
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years to 60 Years
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2026
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Premature, Preterm Infant Health, Vitamin A Deficiency, Human Milk, Breastfeeding
Interventions: Oral multivitamin containing vitamin A; Dietary Supplement
Lead sponsor: University of Mississippi Medical Center; Other
Eligibility: 18 Years to 45 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Jackson, Mississippi

Conditions: Infant Development, Stress
Interventions: Multisensory Early Oral Administration of Human Milk (M-MILK); Other
Lead sponsor: Loyola University; Other
Eligibility: 0 Years to 1 Year
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Maywood, Illinois

Conditions: Hematologic Malignancy
Interventions: BBI608, Dexamethasone, Bortezomib, Imatinib, Ibrutinib; Drug
Lead sponsor: Sumitomo Pharma America, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 8
States / cities: Denver, Colorado • Indianapolis, Indiana • Germantown, Tennessee + 4 more

Conditions: Glioblastoma, Gliosarcoma
Interventions: Imatinib Mesylate & Hydroxyurea; Drug
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 64 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2012
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Osteoporosis, Aging
Interventions: Vitamin D3, Calcium Citrate (Citracal); Dietary Supplement
Lead sponsor: Creighton University; Other
Eligibility: 57 Years and older · Female only
Enrollment: 273 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2011
U.S. locations: 1
States / cities: Omaha, Nebraska

Conditions: Obesity
Interventions: Fecal Microbiota Transplantation, Placebo; Biological · Other
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years and older
Enrollment: 22 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Obesity
Interventions: Exendin 9-39 and Sitagliptin, Placebo; Drug
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 18 Years to 65 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2021
U.S. locations: 1
States / cities: New York, New York

Conditions: Obese Patients (BMI ≥ 30 kg/m²), Glucose Metabolism, Protein Metabolism
Interventions: Indispensable Amino Acid Oxidation, Stable Isotope Oral Glucose Tolerance Test; Procedure
Lead sponsor: University of Illinois at Urbana-Champaign; Other
Eligibility: 19 Years to 59 Years
Enrollment: 8 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Urbana, Illinois

Conditions: Diet, Healthy, Food, Nutrition, Intensive Care, Abdominal Trauma, Surgery, Intra-abdominal Infection, Sepsis, Ischemic Bowel, Vascular, Penetrating Abdominal Trauma, Enteral Feeding, Oral
Interventions: Nutrition Ecosystem pathway, Comparator; Combination Product · Other
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Obesity and Overweight
Interventions: fMRI cue reactivity task, fMRI go no go task, Ad libitum meal test, Eating in the absence of hunger test; Other
Lead sponsor: Johns Hopkins University; Other
Eligibility: 7 Years to 12 Years
Enrollment: 210 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2029
U.S. locations: 4
States / cities: Baltimore, Maryland • Providence, Rhode Island • Seattle, Washington

Conditions: Autonomic Failure, Orthostatic Hypotension
Interventions: Atomoxetine, Acarbose, Pyridostigmine Bromide, Yohimbine, Midodrine HCl, placebo, Modafinil, Octreotide, water intake, Diphenhydramine Hydrochloride, Ranitidine HCL, Tranylcypromine, Ergotamine/ Caffeine, Celecoxib, Pseudoephedrine, Methylphenidate, Indomethacin, Ibuprofen, Oxymetazoline 0.05% nasal solution, Bovril, Acetazolamide, Rivastigmine tartrate, Carbidopa/levodopa, Inflatable abdominal binder, inflatable abdominal binder (sham); Drug · Other · Dietary Supplement + 1 more
Lead sponsor: Vanderbilt University; Other
Eligibility: 18 Years to 85 Years
Enrollment: 389 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2017
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Opioid-Induced Constipation (OIC)
Interventions: NKTR-118, Placebo; Drug
Lead sponsor: AstraZeneca; Industry
Eligibility: 18 Years to 84 Years
Enrollment: 302 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 90
States / cities: Birmingham, Alabama • Calera, Alabama • Glendale, Arizona + 87 more

Conditions: Diabetes Mellitus, Diabetic Ketoacidosis
Interventions: Early feeding with an oral diet; Other
Lead sponsor: Texas Tech University Health Sciences Center; Other
Eligibility: 18 Years to 89 Years
Enrollment: 93 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Lubbock, Texas

Conditions: Overweight and Obesity
Interventions: Water intake and weight control in older adults - Premeal Water + hypocaloric diet, Water intake and weight control in older adults - Total Daily Water + hypocaloric diet, Water Intake and weight control in older adults - hypocaloric diet alone; Behavioral
Lead sponsor: Virginia Polytechnic Institute and State University; Other
Eligibility: 50 Years and older
Enrollment: 375 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2028
U.S. locations: 1
States / cities: Blacksburg, Virginia

Conditions: Dry Mouth
Interventions: Marketed Dry Mouth Rinse, Water control, Experimental Dry Mouth Rinse; Device · Other
Lead sponsor: Procter and Gamble; Industry
Eligibility: 18 Years and older
Enrollment: 22 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019
U.S. locations: 1
States / cities: Mason, Ohio

Conditions: Endothelial Dysfunction, Hypertension
Interventions: Intralipid 20% @ 20cc/hour, Intralipid 20%@ 40cc/hour, Normal Saline, 32-gram oral fat load, 64-gram oral fat load; Drug · Dietary Supplement
Lead sponsor: Emory University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 13 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2008
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Advanced Solid Tumors
Interventions: RO7623066, Olaparib, Carboplatin; Drug
Lead sponsor: Hoffmann-La Roche; Industry
Eligibility: 18 Years and older
Enrollment: 116 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 15
States / cities: Orange, California • New Haven, Connecticut • Detroit, Maine + 12 more

Conditions: Systemic Lupus Erythematosus
Interventions: Matching placebo, Cenerimod; Drug
Lead sponsor: Viatris Innovation GmbH; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 105 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 2
States / cities: Anniston, Alabama • Clearwater, Florida

Conditions: Dehydration, Diabetes Mellitus, Type 2
Interventions: Water Intake; Other
Lead sponsor: Arizona State University; Other
Eligibility: 30 Years to 55 Years
Enrollment: 7 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019
U.S. locations: 1
States / cities: Phoenix, Arizona

Conditions: Low Fluid Intake, Chronic
Interventions: Water Intake; Behavioral
Lead sponsor: University of Illinois at Urbana-Champaign; Other
Eligibility: 9 Years to 10 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2018
U.S. locations: 1
States / cities: Urbana, Illinois

Conditions: Sleep Apnea, Healthy, Vasoconstriction, Vasodilation
Interventions: Hypoxic exposure, modified Oxford test, Oral Bosentan 62.5 mg, Hypoxic ventilatory response test; Other · Drug
Lead sponsor: University of Missouri-Columbia; Other
Eligibility: 18 Years to 45 Years
Enrollment: 54 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2021
U.S. locations: 2
States / cities: Columbia, Missouri • Rochester, Missouri

Conditions: Pregnancy, Child Development
Interventions: DHA, Sugar pill; Dietary Supplement
Lead sponsor: University of Chicago; Other
Eligibility: 18 Years to 34 Years · Female only
Enrollment: 168 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2027
U.S. locations: 1
States / cities: Chicago, Illinois

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Examination of Bromocriptine on Homeostatic and Hedonic Mechanisms of Food Intake in Individuals at High Risk for T2DM

Salt-Sensitivity and Immunity Cell Activation

Vitamin A Supplementation and Breast Milk Vitamin A Levels in Mothers of Preterm Infants

Multisensory Early Oral Administration of Human Milk in Preterm Infants

A Study of BBI608 in Adult Patients With Advanced, Refractory Hematologic Malignancies

Phase II Imatinib + Hydroxyurea in Treatment of Patients With Recurrent/Progressive Grade II Low-Grade Glioma (LGG)

Vitamin D Supplementation in Older Women

Fecal Microbiota Transplantation for the Treatment of Obesity

Mechanisms Underlying Predictors of Success From Obesity Surgery

Stable Isotopes- Adults With Obesity

The PASTDUe Nutrition Ecosystem Project (PASTDUe)

Brain and Behavior Influences on Obesity Development From Infancy Through Childhood

Treatment of Orthostatic Hypotension in Autonomic Failure

A 12-week Extension of the Phase III Study (D3820C00004) to Assess the Effect and Safety of NKTR-118 in Patients With Non-cancer-related Pain and Opioid-induced Constipation

Starvation in the Treatment of Diabetic Ketoacidosis

Water Intake and Weight Control in Older Adults

A Pilot Study to Assess Dry Mouth Relief After Using an Experimental Mouth Rinse

FFA-Induced Hypertension and Endothelial Dysfunction

A Phase 1 Study of RO7623066 Alone and in Combination in Patients With Advanced Solid Tumors

Clinical Study to Investigate the Biological Activity, Safety, Tolerability, and Pharmacokinetics of ACT-334441 in Subjects With Systemic Lupus Erythematosus

INDIGO-2: The Effect of High Water Intake on Glucose Regulation in Low-drinkers

Water Intervention for Thinking in Kids (WITiKids ) Study

Reflex Responses to Intermittent Hypoxia in Humans: Mechanisms and Consequences

Improving Maternal and Child Health Through Prenatal Fatty Acid Supplementation