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ClinicalTrials.gov public records Last synced Oct 7, 2026, 3:44 PM EDT

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Showing 121–144 of 144 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: osteopathic manipulative treatment Clear all
Completed Not applicable Interventional

Effect of OMT on Asthma Symptoms in Southwest Virginia

NCT00545376
View directory record Official record
Conditions
Asthma
Interventions
Osteopathic Manipulative Treatment - in clinic, Osteopathic Manipulative Treatment - at home, Education to physicians
Procedure · Other
Lead sponsor
Edward Via Virginia College of Osteopathic Medicine
Other
Eligibility
5 Years to 55 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Blacksburg, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 22, 2019 · Synced Oct 7, 2026, 3:44 PM EDT
Not yet recruiting Phase 4 Interventional

OMT for Adhesive Capsulitis

NCT07497737
View directory record Official record
Conditions
Adhesive Capsulitis of the Shoulder, Frozen Shoulder
Interventions
Intra-articular Injection, Osteopathic Manipulative Therapy (OMT)
Drug · Other
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 89 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
3
States / cities
Beachwood, Ohio • Westlake, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 5, 2026 · Synced Oct 7, 2026, 3:44 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Ultrasonographic Evaluation of Osteopathic Manipulation for Thoracic Outlet Syndrome

NCT06273969
View directory record Official record
Conditions
Thoracic Outlet Syndrome
Interventions
Osteopathic Manipulative Treatment (OMT)
Other
Lead sponsor
A.T. Still University of Health Sciences
Other
Eligibility
18 Years to 65 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Kirksville, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 24, 2024 · Synced Oct 7, 2026, 3:44 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Examining the Impact of Mindfulness on Patients' Experience of Osteopathic Manipulation

NCT04477278
View directory record Official record
Conditions
Pain, Satisfaction, Patient
Interventions
Mindfulness Meditation, History of Osteopathy
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jul 20, 2020 · Synced Oct 7, 2026, 3:44 PM EDT
Completed Not applicable Interventional

Investigating the Efficacy of Osteopathic Manipulative Treatment on Gait Dysfunction Following Knee Surgery

NCT05580640
View directory record Official record
Conditions
Knee Arthroscopy, Knee Arthroplasty, Osteopathic Manipulative Treatment, Gait, Unsteady
Interventions
OMT
Procedure
Lead sponsor
Midwestern University
Other
Eligibility
21 Years to 90 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Downers Grove, Illinois
Source: ClinicalTrials.gov public record
Updated May 19, 2023 · Synced Oct 7, 2026, 3:44 PM EDT
Recruiting Not applicable Interventional

How Osteopathic Treatment Affects the Leg and Foot in People With Low Back Pain

NCT07193212
View directory record Official record
Conditions
Chronic Low Back Pain (CLBP)
Interventions
Osteopathic Manipulative Treatment
Other
Lead sponsor
Edward Via Virginia College of Osteopathic Medicine
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Auburn, Alabama
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Oct 7, 2026, 3:44 PM EDT
Completed Not applicable Interventional

The Effect of Osteopathic Treatment on Craniocervico-Mandibular Dysfunction

NCT06471426
View directory record Official record
Conditions
Headache, Neck Pain
Interventions
Osteopathic Manipulative Treatment
Other
Lead sponsor
Edward Via Virginia College of Osteopathic Medicine
Other
Eligibility
19 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Auburn, Alabama
Source: ClinicalTrials.gov public record
Updated Sep 11, 2026 · Synced Oct 7, 2026, 3:44 PM EDT
Enrolling by invitation No phase listed Observational

Use of Osteopathic Manipulative Treatment for Non-musculoskeletal Conditions

NCT06072599
View directory record Official record
Conditions
Manipulation, Osteopathic
Interventions
Not listed
Lead sponsor
A.T. Still University of Health Sciences
Other
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Kirksville, Missouri
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Oct 7, 2026, 3:44 PM EDT
Completed Early Phase 1 Interventional Results available

The Effectiveness of Osteopathic Manipulative Medicine in the Management of Headaches Associated With Post Concussion Syndrome

NCT04732338
View directory record Official record
Conditions
Headache, Post-Concussion Syndrome
Interventions
Osteopathic Manipulative Therapy
Other
Lead sponsor
Hackensack Meridian Health
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Edison, New Jersey
Source: ClinicalTrials.gov public record
Updated May 25, 2021 · Synced Oct 7, 2026, 3:44 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Prevalence of Chapman Reflex Points in Medical Students and Their Association With Visceral Symptoms

NCT07691112
View directory record Official record
Conditions
Healthy, Autonomic Nervous System Diseases, Lymphatic Diseases, Somatic Dysfunction, Chapman Reflex Points
Interventions
Chapman Reflex Point Examination
Procedure
Lead sponsor
The Touro College and University System
Other
Eligibility
18 Years and older
Enrollment
101 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Oct 7, 2026, 3:44 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Osteopathic Manipulative Therapy Effects on Prolonged Post-COVID Olfactory Dysfunction

NCT05112887
View directory record Official record
Conditions
COVID-19 Lower Respiratory Infection, SARS-CoV2 Infection
Interventions
Osteopathic Manipulative Therapy
Other
Lead sponsor
Ohio University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Dublin, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 9, 2021 · Synced Oct 7, 2026, 3:44 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Alterations in Bioelectric Activity at Acupuncture Points Following CV4 Cranial Manipulation

NCT05190731
View directory record Official record
Conditions
Autonomic Imbalance
Interventions
Osteopathic cranial manipulative medicine, Sham
Other
Lead sponsor
Jan T Hendryx
Other
Eligibility
18 Years to 78 Years
Enrollment
77 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Erie, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 22, 2022 · Synced Oct 7, 2026, 3:44 PM EDT
Not listed Not applicable Interventional

Efficacy of Osteopathic Manipulative Medicine (OMM) and Phototherapy for Patients With Chronic Lower Back Pain

NCT01765777
View directory record Official record
Conditions
Chronic Lower Back Pain
Interventions
Osteopathic Manipulative Medicine, Phototherapy
Procedure
Lead sponsor
New York Institute of Technology
Other
Eligibility
18 Years to 65 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2025
U.S. locations
1
States / cities
Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated Aug 6, 2024 · Synced Oct 7, 2026, 3:44 PM EDT
Not yet recruiting Not applicable Interventional

Osteopathic Manipulative Treatment for Children With Chronic or Recurrent Otitis Media

NCT07639775
View directory record Official record
Conditions
Otitis Media, Otitis Media Effusion, Otitis Media Recurrent, Otitis Media With Effusion in Children, Otitis Media Chronic, Otitis Media in Children, Tympanostomy Tube Insertion, Osteopathic Manipulative Treatment (OMT)
Interventions
Experimental Osteopathic Manipulative Treatment (OMT) Protocol, Control Osteopathic Manipulative Treatment (OMT) Protocol
Other
Lead sponsor
Sarah Vidal
Other
Eligibility
6 Months to 6 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
Lynchburg, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Oct 7, 2026, 3:44 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Nutrient Nutritional Advise for Low Back Pain Patients Seeking Chiropractic Care

NCT04134013
View directory record Official record
Conditions
Low Back Pain, Nutrition Poor
Interventions
Combination: Nutrition AND Chiropractic Adjustment, Chiropractic Adjustment: Spinal Manipulation Therapy
Dietary Supplement · Other
Lead sponsor
Parker University
Other
Eligibility
21 Years to 65 Years
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Plano, Texas
Source: ClinicalTrials.gov public record
Updated Jan 14, 2022 · Synced Oct 7, 2026, 3:44 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Use of Osteopathic Medical Manipulation to Decrease the Incidence and Severity of Post-Operative Sore Throat

NCT03720301
View directory record Official record
Conditions
Pharyngitis, Dysphonia
Interventions
Osteopathic Manipulation Treatment, Sham
Procedure
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years and older
Enrollment
168 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Oct 25, 2018 · Synced Oct 7, 2026, 3:44 PM EDT
Completed Not applicable Interventional

Osteopathic Manipulative Techniques in Collegiate Dancers

NCT06858592
View directory record Official record
Conditions
Osteopathic Manipulative Treatment (OMT), Dance Therapy
Interventions
Osteopathic Manipulative Treatment (OMT)
Procedure
Lead sponsor
Edward Via Virginia College of Osteopathic Medicine
Other
Eligibility
Female only
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Monroe, Louisiana
Source: ClinicalTrials.gov public record
Updated Mar 5, 2025 · Synced Oct 7, 2026, 3:44 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Pregnancy-Related Low Back Pain and Complementary and Alternative Medicine (CAM) Treatment

NCT00937365
View directory record Official record
Conditions
Low Back Pain
Interventions
Exercise, Spinal Manipulation, Neuroemotional Technique (NET)
Behavioral · Procedure
Lead sponsor
Oregon Health and Science University
Other
Eligibility
20 Years to 49 Years · Female only
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Dec 18, 2019 · Synced Oct 7, 2026, 3:44 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Anti-inflammatory Actions of Osteopathic Manipulative Treatment

NCT04177264
View directory record Official record
Conditions
Inflammation
Interventions
Occipito-Atlantal Decompression (OA DC), Sham Occipito-Atlantal Decompression (Sham OA DC), Splenic Lymphatic Pump Technique (SpLPT), Sham Splenic Lymphatic Pump Technique (Sham SpLPT), Transcutaneous Auricular Vagus Nerve Stimulation (taVNS), Sham Transcutaneous Auricular Vagus Nerve Stimulation (Sham taVNS)
Procedure · Device
Lead sponsor
Burrell College of Health Sciences
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Las Cruces, New Mexico
Source: ClinicalTrials.gov public record
Updated Feb 8, 2023 · Synced Oct 7, 2026, 3:44 PM EDT
Recruiting Not applicable Interventional

Effects of Osteopathic Manipulative Treatment Protocol on Sleep Quality in Parkinson's Disease Subjects

NCT06671600
View directory record Official record
Conditions
Parkinsons Disease, Sleep
Interventions
Osteopathic Manipulative Treatment, Sham (No Treatment)
Procedure
Lead sponsor
New York Institute of Technology
Other
Eligibility
Not listed
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Oct 7, 2026, 3:44 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Osteopathic Manipulation Therapy in the Treatment of Interstitial Cystitis

NCT00873171
View directory record Official record
Conditions
Interstitial Cystitis
Interventions
Not listed
Lead sponsor
CAMC Health System
Other
Eligibility
18 Years to 90 Years · Female only
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
1
States / cities
Charleston, West Virginia
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Oct 7, 2026, 3:44 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Spencer's Technique on Shoulder Function

NCT06447493
View directory record Official record
Conditions
Shoulder
Interventions
Osteopathic Manipulative Treatment-Spencer's Technique (Modified), Rest
Other
Lead sponsor
Edward Via Virginia College of Osteopathic Medicine
Other
Eligibility
18 Years to 50 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Auburn, Alabama
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Oct 7, 2026, 3:44 PM EDT
Completed Not applicable Interventional

Effect of Osteopathic Manipulative Medicine (OMM) on Pulmonary Function and Speech in Parkinson's Disease

NCT01636011
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Osteopathic Manipulative Medicine Treatment, Light Touch sham
Other
Lead sponsor
New York Institute of Technology
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated Oct 16, 2017 · Synced Oct 7, 2026, 3:44 PM EDT
Completed Not applicable Interventional

The Use of Manual Therapy to Treat Low-Back and Hip Pain

NCT00410397
View directory record Official record
Conditions
Low Back Pain, Pain
Interventions
Osteopathic Manipulative Medicine, Sham Manipulation
Procedure
Lead sponsor
Oklahoma State University Center for Health Sciences
Other
Eligibility
18 Years to 60 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jan 15, 2008 · Synced Oct 7, 2026, 3:44 PM EDT