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Showing 1–24 of 291 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: oxytocin (Pitocin) Clear all
Terminated Not applicable Interventional Results available

Open-label Study of the Efficacy of Intranasal Oxytocin in Schizophrenia

NCT02144155
View directory record Official record
Conditions
Schizophrenia
Interventions
Oxytocin: 24IU - 168 IU, Placebo
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Dec 8, 2019 · Synced Sep 27, 2026, 8:38 AM EDT
Withdrawn Phase 2 Interventional Accepts healthy volunteers

Validate a Pharmacodynamic Model of Oxytocin for Peripheral Analgesic Effects

NCT04435704
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
Oxytocin
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 75 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Sep 27, 2026, 8:38 AM EDT
Not listed Phase 1 Interventional

Oxytocin in Opiate Dependence: A Pilot Study of the Effects of Intranasal Oxytocin on Emotional Processes and Stress Responses in Patients With Opiate Dependence

NCT02052258
View directory record Official record
Conditions
Opiate Dependence
Interventions
Oxytocin
Drug
Lead sponsor
MacDonald, Kai, M.D.
Individual
Eligibility
18 Years and older · Male only
Timeline
Started 2013
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 14, 2014 · Synced Sep 27, 2026, 8:38 AM EDT
Terminated Not applicable Interventional

Optimizing the Social Engagement System in Prader-Willi Syndrome: Insights From the Polyvagal Theory

NCT03101826
View directory record Official record
Conditions
Prader-Willi Syndrome
Interventions
Listening Project Protocol
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
13 Years to 25 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Brewster, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 2, 2023 · Synced Sep 27, 2026, 8:38 AM EDT
Completed Phase 2 Interventional Results available

Oxytocin or Galantamine Versus Placebo for the Treatment of Negative Symptoms and Cognitive Impairments in Schizophrenia

NCT01012167
View directory record Official record
Conditions
Schizophrenia
Interventions
Oxytocin, Galantamine, Placebo-Oxytocin, Placebo-Galantamine
Drug · Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 64 Years
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
6
States / cities
Baltimore, Maryland • Catonsville, Maryland • Dundalk, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 11, 2022 · Synced Sep 27, 2026, 8:38 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Meditation for Emotional Numbing in Post-Traumatic Stress Disorder

NCT02163941
View directory record Official record
Conditions
Prolonged Post-traumatic Stress Disorder
Interventions
Compassion Training
Behavioral
Lead sponsor
Emory University
Other
Eligibility
25 Years to 65 Years · Male only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 1, 2016 · Synced Sep 27, 2026, 8:38 AM EDT
Completed Phase 1 Interventional

Oxytocin Treatment of Social Cognitive and Functional Deficits in Schizophrenia

NCT01394471
View directory record Official record
Conditions
Schizophrenia, Schizoaffective Disorder
Interventions
Intranasal Oxytocin Spray
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 65 Years
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 10, 2015 · Synced Sep 27, 2026, 8:38 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Oxytocin and Social Behavior Over the Lifespan

NCT00914953
View directory record Official record
Conditions
Social Activity
Interventions
oxytocin (Pitocin)
Drug
Lead sponsor
Claremont Graduate University
Other
Eligibility
50 Years and older
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Mar 1, 2012 · Synced Sep 27, 2026, 8:38 AM EDT
Completed Not applicable Interventional

Outpatient Foley For Starting Induction of Labor at Term in Nulliparous Women

NCT03472937
View directory record Official record
Conditions
Pregnancy Related
Interventions
Transcervical Foley catheter placement for cervical ripening
Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older · Female only
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Feb 5, 2020 · Synced Sep 27, 2026, 8:38 AM EDT
Active, not recruiting Not applicable Interventional

Calcium Carbonate on Labor Induction

NCT06352775
View directory record Official record
Conditions
Pregnancy, Uterine Contraction
Interventions
Calcium Carbonate
Dietary Supplement
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older · Female only
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Nov 20, 2025 · Synced Sep 27, 2026, 8:38 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

A Trial of Oral Misoprostol for Labor Augmentation

NCT00906347
View directory record Official record
Conditions
Labor Augmentation
Interventions
Misoprostol, Oxytocin
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
16 Years and older · Female only
Enrollment
350 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Nov 14, 2012 · Synced Sep 27, 2026, 8:38 AM EDT
Completed Phase 2 Interventional Results available

A Study of Oxytocin in Children and Adolescents With Autistic Disorder

NCT01308749
View directory record Official record
Conditions
Autism
Interventions
Oxytocin, Placebo
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
3 Years to 17 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 16, 2017 · Synced Sep 27, 2026, 8:38 AM EDT
Completed Not applicable Interventional Results available

Effect of Intranasal Oxytocin on Headache in Chronic Daily Headache

NCT00963040
View directory record Official record
Conditions
Chronic Daily Headache
Interventions
Syntocinon, Sterile water
Drug
Lead sponsor
MedVadis Research Corporation
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Wellesley Hills, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 14, 2023 · Synced Sep 27, 2026, 8:38 AM EDT
Not listed Phase 2 Interventional

Intranasal Oxytocin for Frontotemporal Dementia

NCT03260920
View directory record Official record
Conditions
Frontotemporal Dementia
Interventions
Syntocinon
Drug
Lead sponsor
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Other
Eligibility
30 Years to 80 Years
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
5
States / cities
Los Angeles, California • San Francisco, California • Baltimore, Maryland + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 14, 2023 · Synced Sep 27, 2026, 8:38 AM EDT
Enrolling by invitation Phase 2 Interventional

Efficacy of Intravenous Oxytocin to Speed Recovery After THA

NCT07430228
View directory record Official record
Conditions
Total Hip Arthroplasty
Interventions
intravenous administration of oxytocin, Placebo
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 75 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 23, 2026 · Synced Sep 27, 2026, 8:38 AM EDT
Completed Phase 2 Interventional Results available

Intranasal Oxytocin in the Treatment of Autism

NCT00490802
View directory record Official record
Conditions
Autism
Interventions
Oxytocin, Placebo
Drug
Lead sponsor
Evdokia Anagnostou
Individual
Eligibility
18 Years to 60 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 22, 2015 · Synced Sep 27, 2026, 8:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Neurobiological Bases of Paternal Nurturance

NCT02223429
View directory record Official record
Conditions
Healthy
Interventions
Oxytocin, Vasopressin, Placebo
Drug
Lead sponsor
James K. Rilling, PhD
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
2
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 4, 2017 · Synced Sep 27, 2026, 8:38 AM EDT
Completed Phase 4 Interventional Results available

A Pilot Study: High Versus Low Oxytocin Dosing for Induction of Labor in Pregnant Patients With Obesity

NCT05289869
View directory record Official record
Conditions
Pregnant Patients With Obesity
Interventions
High-dose oxytocin, Low-dose oxytocin
Drug
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 28, 2023 · Synced Sep 27, 2026, 8:38 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Dose Ranging Study of Intravenous Oxytocin for Analgesia to Heat Pain

NCT05179421
View directory record Official record
Conditions
Healthy Volunteer Study
Interventions
Low dose oxytocin, High dose oxytocin
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 75 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 18, 2024 · Synced Sep 27, 2026, 8:38 AM EDT
Completed Phase 4 Interventional Results available

Oxytocin Dosage to Decrease Induction Duration

NCT03140488
View directory record Official record
Conditions
Obesity, Labor, Induced, Oxytocin
Interventions
Oxytocin
Drug
Lead sponsor
University of Arizona
Other
Eligibility
18 Years and older · Female only
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Dec 19, 2022 · Synced Sep 27, 2026, 8:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Using Affectionate Communication as a Response to Acute Stress

NCT00468572
View directory record Official record
Conditions
Stress
Interventions
Affectionate Writing, Meaningless Writing
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
18 Years to 75 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007
U.S. locations
1
States / cities
Tempe, Arizona
Source: ClinicalTrials.gov public record
Updated Jan 9, 2012 · Synced Sep 27, 2026, 8:38 AM EDT
Completed Not applicable Interventional Results available

Length of Cook Catheter Placement and Induction of Labor

NCT04233008
View directory record Official record
Conditions
Induction of Labor
Interventions
Foley catheter length
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
178 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 23, 2022 · Synced Sep 27, 2026, 8:38 AM EDT
Completed Phase 1 Interventional

Laboratory Studies on Oxytocin for Treatment of Alcohol Use Disorder

NCT02407340
View directory record Official record
Conditions
Alcoholism, Alcohol Related Disorders
Interventions
oxytocin, placebo
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years to 50 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 3, 2017 · Synced Sep 27, 2026, 8:38 AM EDT
Completed Not applicable Interventional

A Randomized Study on Comparing the Efficacy of Foley Catheter and Extraamniotic Saline Infusion for Labor Induction

NCT00366951
View directory record Official record
Conditions
Cervical Ripening, Labor, Induced
Interventions
Foley catheter only, Extraamniotic saline infusion
Procedure
Lead sponsor
Rush University Medical Center
Other
Eligibility
Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 9, 2008 · Synced Sep 27, 2026, 8:38 AM EDT