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ClinicalTrials.gov public records Last synced Oct 21, 2026, 1:02 PM EDT

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Showing 1–19 of 19 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: pQCT Clear all
Completed No phase listed Observational Accepts healthy volunteers

Does Bone Structure Explain the Increased Fracture Risk in Type II Diabetes Patients? A Pilot Study

NCT00703417
View directory record Official record
Conditions
Osteoporosis
Interventions
magnetic Resonance Imaging, Computed Tomography, High resolution peripheral quantitative computed tomography
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
55 Years to 75 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 8, 2011 · Synced Oct 21, 2026, 1:02 PM EDT
Withdrawn Phase 4 Interventional

The Effects of Alendronate After Cure of Primary Hyperparathyroidism

NCT00359385
View directory record Official record
Conditions
Hyperparathyroidism
Interventions
Alendronate 70mg weekly
Drug
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 16, 2011 · Synced Oct 21, 2026, 1:02 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Genetic Studies of Insulin and Diabetes

NCT00001987
View directory record Official record
Conditions
Diabetes Mellitus, Severe Insulin Resistance
Interventions
HR-pQCT scan
Device
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
6 Months to 120 Years
Enrollment
1,200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 1976
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 21, 2026, 1:02 PM EDT
Completed Phase 2 Interventional Results available

Denosumab, Teriparatide or Both for the Treatment of Postmenopausal Osteoporosis

NCT00926380
View directory record Official record
Conditions
Osteoporosis
Interventions
denosumab, teriparatide
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
45 Years and older · Female only
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 29, 2018 · Synced Oct 21, 2026, 1:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Trial of Lithium Carbonate for Treatment of Osteoporosis-pseudoglioma Syndrome

NCT01108068
View directory record Official record
Conditions
Osteoporosis Pseudoglioma
Interventions
Lithium
Drug
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
4 Years to 64 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Lancaster, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 4, 2019 · Synced Oct 21, 2026, 1:02 PM EDT
Completed Phase 1 Interventional Results available

Safety of Fresolimumab in the Treatment of Osteogenesis Imperfecta

NCT03064074
View directory record Official record
Conditions
Osteogenesis Imperfecta
Interventions
Fresolimumab
Drug
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
2
States / cities
Portland, Oregon • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 4, 2024 · Synced Oct 21, 2026, 1:02 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

DXA Study of Precision and Reliability

NCT03621306
View directory record Official record
Conditions
Bone and Bones, Body Composition
Interventions
DXA and pQCT precision testing
Device
Lead sponsor
Penn State University
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2028
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Oct 21, 2026, 1:02 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Do Serotonin Reuptake Inhibitors (SSRIs) Affect Bone Mass in Adolescents

NCT02147184
View directory record Official record
Conditions
The Skeletal Effects of SSRIs
Interventions
Not listed
Lead sponsor
Chadi A. Calarge
Other
Eligibility
15 Years to 20 Years
Enrollment
287 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2016
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jun 28, 2023 · Synced Oct 21, 2026, 1:02 PM EDT
Completed No phase listed Observational

Bone Mineral Density in Adult Survivors of Solid Pediatric Cancers

NCT00634816
View directory record Official record
Conditions
Regional Osteoporosis as a Result of Chemotherapy
Interventions
DXA Scan
Radiation
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
16 Years to 40 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2006
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated May 30, 2013 · Synced Oct 21, 2026, 1:02 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

The Impact of Glomerular Disorders on Bone Quality and Strength

NCT04528446
View directory record Official record
Conditions
Glomerular Disease, Bone Diseases, Metabolic, Bone Fracture
Interventions
Dual-energy X-ray absorptiometry, High Resolution Peripheral Quantitative Computed Tomography (HR-pQCT), Blood draw and Urine collection, Questionnaires
Radiation · Other
Lead sponsor
Columbia University
Other
Eligibility
5 Years to 55 Years
Enrollment
270 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
2
States / cities
New York, New York • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 1, 2024 · Synced Oct 21, 2026, 1:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Jump-In: Building Better Bones

NCT00729378
View directory record Official record
Conditions
Adolescent Development
Interventions
Skeletal loading
Other
Lead sponsor
University of Arizona
Other
Eligibility
9 Years to 12 Years · Female only
Enrollment
509 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2013
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Oct 28, 2025 · Synced Oct 21, 2026, 1:02 PM EDT
Completed No phase listed Observational

Bone Mineral Density Status in Pediatric and Adolescent Survivors of Childhood Cancer With History of Bone Fracture

NCT02355340
View directory record Official record
Conditions
Bone Mineral Density, Childhood Cancer Survivors
Interventions
Dual energy x-ray absorptiometry (DXA), Peripheral quantitative computed tomography (pQCT)
Other
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
8 Years to 20 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2024
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 6, 2024 · Synced Oct 21, 2026, 1:02 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Bone Microarchitecture at the Radius: a Pilot Comparison Between Children With Cystic Fibrosis and Healthy Controls

NCT01331980
View directory record Official record
Conditions
Cystic Fibrosis
Interventions
Peripheral quantitative computed tomography (pQCT), Dual X-ray absorptiometry (DXA)
Device
Lead sponsor
University of Arkansas
Other
Eligibility
6 Years to 12 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Jul 3, 2015 · Synced Oct 21, 2026, 1:02 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Assessment of Bone Micro-Architecture Using HR-pQCT

NCT01367730
View directory record Official record
Conditions
Osteoporosis
Interventions
Not listed
Lead sponsor
University of California, San Francisco
Other
Eligibility
50 Years to 85 Years · Male only
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Dec 2, 2014 · Synced Oct 21, 2026, 1:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Relationship Between Irisin and Bone Health in Individuals With Spinal Cord Injury

NCT05319522
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Acute Exercise
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Oct 21, 2026, 1:02 PM EDT
Completed No phase listed Observational

Novel Imaging Markers for Rheumatoid Arthritis

NCT01773681
View directory record Official record
Conditions
Rheumatoid Arthritis
Interventions
Cimzia, Magnetic Resonance Imaging (MRI), High-resolution peripheral quantitative computed tomography (HR-pQCT)
Drug · Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Nov 30, 2018 · Synced Oct 21, 2026, 1:02 PM EDT
Recruiting No phase listed Observational

Precision Medicine Approaches to Renal Osteodystrophy

NCT05880914
View directory record Official record
Conditions
Renal Osteodystrophy, Chronic Kidney Diseases, CKD-MBD, Bone Turnover Rate Disorder, Secondary Hyperparathyroidism
Interventions
miRNAseq analysis, Standard treatment for bone disorder
Procedure · Drug
Lead sponsor
Thomas Nickolas
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 12, 2026 · Synced Oct 21, 2026, 1:02 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Skeletal Health and Bone Marrow Composition in Adolescents With Cystic Fibrosis

NCT06216704
View directory record Official record
Conditions
Cystic Fibrosis
Interventions
Magnetic resonance relaxometry, Magnetic resonance spectroscopy, Blood Draw, DXA, pQCT
Diagnostic Test
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
13 Years to 20 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 30, 2025 · Synced Oct 21, 2026, 1:02 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Skeletal Health and Bone Marrow Composition Among Youth

NCT04203381
View directory record Official record
Conditions
Gender Dysphoria in Children, Puberty, Bone Development
Interventions
GnRH Agonist
Device
Lead sponsor
Amy DiVasta, MD
Other
Eligibility
9 Years to 14 Years
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
2
States / cities
Boston, Massachusetts • Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 3, 2026 · Synced Oct 21, 2026, 1:02 PM EDT