- Conditions
- Smoking Dependence, Smoking
- Interventions
- oral nicotine, Placebo
- Drug
- Lead sponsor
- GlaxoSmithKline
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 323 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2011
- U.S. locations
- 1
- States / cities
- Burbank, California
Search Results
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Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.
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Showing 1–24
of 47
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Tobacco Use Disorder
- Interventions
- Nicotine lozenge 4 mg, Placebo lozenge
- Drug
- Lead sponsor
- University of Minnesota
- Other
- Eligibility
- 18 Years to 64 Years
- Enrollment
- 56 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2015
- U.S. locations
- 1
- States / cities
- Minneapolis, Minnesota
- Conditions
- COVID-19
- Interventions
- Nitric Oxide lozenges, 30 mg, Placebo
- Drug
- Lead sponsor
- Nitric Oxide Innovations LLC
- Industry
- Eligibility
- 50 Years to 85 Years
- Enrollment
- 524 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2022
- U.S. locations
- 1
- States / cities
- Lake Bluff, Illinois
- Conditions
- Pulmonary Disease, Chronic Obstructive, Pulmonary Fibrosis, Cough
- Interventions
- interferon-alpha lozenges, placebo lozenges
- Drug
- Lead sponsor
- Ainos, Inc. (f/k/a Amarillo Biosciences Inc.
- Industry
- Eligibility
- 40 Years and older
- Enrollment
- 1 participant
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2012
- U.S. locations
- 1
- States / cities
- Lubbock, Texas
- Conditions
- Argininosuccinic Aciduria, Argininosuccinate Lyase Deficiency, Urea Cycle Disorders
- Interventions
- Nitric oxide supplement, Placebo
- Dietary Supplement
- Lead sponsor
- Baylor College of Medicine
- Other
- Eligibility
- 8 Years to 64 Years
- Enrollment
- 12 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2018
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Dental Caries
- Interventions
- xylitol, inactive lozenge
- Dietary Supplement
- Lead sponsor
- University of North Carolina, Chapel Hill
- Other
- Eligibility
- 25 Years to 80 Years
- Enrollment
- 709 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2011
- U.S. locations
- 3
- States / cities
- Birmingham, Alabama • Chapel Hill, North Carolina • San Antonio, Texas
- Conditions
- Smokeless Tobacco Use
- Interventions
- Nicotine Lozenges, Placebo lozenge
- Drug
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 270 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2009
- U.S. locations
- 2
- States / cities
- Rochester, Minnesota • Eugene, Oregon
- Conditions
- COVID-19
- Interventions
- chlorine dioxide, zinc acetate, Famotidine, placebo, lactoferrin, green tea extract
- Other · Dietary Supplement · Drug
- Lead sponsor
- Profact, Inc.
- Other
- Eligibility
- 20 Years to 70 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2022
- U.S. locations
- 1
- States / cities
- Tempe, Arizona
- Conditions
- Epilepsy
- Interventions
- Progesterone Lozenges, Matched Placebo Lozenges
- Biological · Other
- Lead sponsor
- Beth Israel Deaconess Medical Center
- Other
- Eligibility
- 13 Years to 45 Years · Female only
- Enrollment
- 294 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2000 – 2010
- U.S. locations
- 14
- States / cities
- Los Angeles, California • Atlanta, Georgia • Baltimore, Maryland + 8 more
- Conditions
- Halitosis
- Interventions
- Biofresh® 4plus, Placebo
- Dietary Supplement
- Lead sponsor
- Novozymes A/S
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 53 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021
- U.S. locations
- 1
- States / cities
- Fort Wayne, Indiana
- Conditions
- Thyroiditis, Autoimmune
- Interventions
- Anatabloc Supplement, Placebo
- Dietary Supplement
- Lead sponsor
- Rock Creek Pharmaceuticals, Inc.
- Industry
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 165 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2013
- U.S. locations
- 9
- States / cities
- West Palm Beach, Florida • Zephyrhills, Florida • La Grange, Illinois + 5 more
- Conditions
- Opioid Use, Pain, Postoperative, Sleep, Delirium
- Interventions
- Melatonin, Placebo
- Dietary Supplement
- Lead sponsor
- Scripps Health
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 120 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2028
- U.S. locations
- 1
- States / cities
- La Jolla, California
- Conditions
- Oral Health
- Interventions
- Oral probiotic, Placebo
- Dietary Supplement
- Lead sponsor
- USANA Health Sciences
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 105 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2022
- U.S. locations
- 1
- States / cities
- South Jordan, Utah
- Conditions
- Oral Malodor
- Interventions
- Experimental lozenge with the enzyme Polyphenol oxidase and green coffee extract, Experimental lozenge with the enzyme Polyphenol oxidase, green coffee extract and flavor, Placebo lozenge control (sorbitol only), No product
- Other
- Lead sponsor
- Novozymes A/S
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 156 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020
- U.S. locations
- 1
- States / cities
- Fort Wayne, Indiana
- Conditions
- Papillomatosis, HIV Infections
- Interventions
- Interferon-alpha, placebo
- Drug · Other
- Lead sponsor
- Ainos, Inc. (f/k/a Amarillo Biosciences Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 59 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2009
- U.S. locations
- 12
- States / cities
- San Francisco, California • Fort Lauderdale, Florida • Augusta, Georgia + 9 more
- Conditions
- Acute Pharyngitis, Sore Throat
- Interventions
- flurbiprofen, placebo
- Drug
- Lead sponsor
- Reckitt Benckiser LLC
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 122 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2014
- U.S. locations
- 1
- States / cities
- Storrs, Connecticut
- Conditions
- Prehypertension
- Interventions
- Nitric Oxide supplement, Placebo
- Dietary Supplement
- Lead sponsor
- Neogenis Laboratories
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- Started 2013
- U.S. locations
- 1
- States / cities
- Beverly Hills, California
- Conditions
- Oral Health
- Interventions
- PTx800 lozenges, Placebo control
- Dietary Supplement
- Lead sponsor
- Primal Therapies Inc.
- Industry
- Eligibility
- 60 Years to 85 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Alzheimer Disease
- Interventions
- Anatabloc(R), Placebo
- Dietary Supplement
- Lead sponsor
- Rock Creek Pharmaceuticals, Inc.
- Industry
- Eligibility
- 65 Years to 90 Years
- Enrollment
- 85 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2015
- U.S. locations
- 1
- States / cities
- Sarasota, Florida
- Conditions
- Smoking Cessation, Smoking, Nicotine Dependence
- Interventions
- CIS - telephone cessation quitline counseling, Lozenge - nicotine mini-lozenges, Emails - Brief smoking prevention messages, Full website - standard smokefree.gov website content, Lite website - lite version of smokefree.gov, Full mailed booklet - NCI's detailed 36-page quit guide, brief mailed booklet - smaller version of NCI's booklet
- Other
- Lead sponsor
- University of Wisconsin, Madison
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 1,034 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2013
- U.S. locations
- 1
- States / cities
- Madison, Wisconsin
- Conditions
- Smoking, Smoking Cessation
- Interventions
- Nicotine lower dose, Nicotine higher dose, Placebo
- Drug
- Lead sponsor
- GlaxoSmithKline
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 187 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010
- U.S. locations
- 1
- States / cities
- Burbank, California
- Conditions
- Tobacco Use Disorder, Smoking
- Interventions
- Ariva Silver Wintergreen, Placebo Wintergreen
- Other
- Lead sponsor
- Star Scientific, Inc
- Industry
- Eligibility
- 23 Years to 72 Years
- Enrollment
- 43 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2009
- U.S. locations
- 1
- States / cities
- Martinsburg, West Virginia
- Conditions
- Nicotine Addiction
- Interventions
- Nicotine polacrilex, Placebo, satiety, abstinence
- Drug · Other
- Lead sponsor
- Duke University
- Other
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 54 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2014 – 2016
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Smoking
- Interventions
- Nicotine Lozenge, Placebo Lozenge, Abstinence Advisement
- Drug · Behavioral
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 46 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2013
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota