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Showing 1–24 of 412 matching trials from the live ClinicalTrials.gov search.
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Completed Not applicable Interventional Accepts healthy volunteers Results available

Targeted CPAP Therapy for Obstructive Sleep Apnea in Pregnancy

NCT02755831
Conditions
Obstructive Sleep Apnea
Interventions
CPAP, Pre-natal care
Device · Other
Lead sponsor
United States Naval Medical Center, San Diego
Federal
Eligibility
18 Years and older · Female only
Enrollment
193 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
San Diego, California
Conditions
Restless Legs Syndrome, Restless Legs Syndrome (RLS)
Interventions
GSK1838262 Extended Release Tablets, Placebo
Drug
Lead sponsor
XenoPort, Inc.
Industry
Eligibility
18 Years and older
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
24
States / cities
Jasper, Alabama • San Diego, California • Hallandale, Florida + 20 more
Conditions
Obstructive Sleep Apnea, Central Sleep Apnea, Mixed Sleep Apnea, Cheyne-Stokes Respiration
Interventions
SomnaPatch, Polysomnography
Device
Lead sponsor
Somnarus Inc
Industry
Eligibility
20 Years to 85 Years
Enrollment
190 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
3
States / cities
Little Rock, Arkansas • Burlingame, California • Tampa, Florida
Conditions
Parkinson Disease
Interventions
Nighttime Deep Brain Stimulation with Varying Amplitude Settings
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Completed Phase 4 Interventional Accepts healthy volunteers

Ezopiclone Improves the Quality of Overnight Polysomnography

NCT00507117
Conditions
Obstructive Sleep Apnea
Interventions
Lunesta, Placebo control
Drug
Lead sponsor
Walter Reed Army Medical Center
Federal
Eligibility
18 Years to 64 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Conditions
Obstructive Sleep Apnea, Total Knee Arthroplasty
Interventions
Not listed
Lead sponsor
United States Naval Medical Center, San Diego
Federal
Eligibility
18 Years to 90 Years
Enrollment
93 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
San Diego, California
Conditions
Movement Disorders (Incl Parkinsonism), Tremor Familial Essential, 1, REM Sleep Behavior Disorder
Interventions
Not listed
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years to 85 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
Birmingham, Alabama
Conditions
Parkinson Disease, REM Behavior Disorder
Interventions
Sleep, PD and DBS
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 80 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Aurora, Colorado
Conditions
Insomnia
Interventions
Sound Treatment
Device
Lead sponsor
Third Wave Therapeutics
Industry
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
San Francisco, California
Not listed No phase listed Observational Accepts healthy volunteers

The Effect of Obstructive Sleep Apnea and Its Treatment on Decision Making

NCT03262519
Conditions
Obstructive Sleep Apnea
Interventions
Computer based neurocognitive testing
Diagnostic Test
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 75 Years
Enrollment
96 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
San Diego, California
Conditions
Sleep Disorder, Depressive; Behavioral Disorder, Mood Disorders
Interventions
MEB-001
Device
Lead sponsor
Medibio Limited
Industry
Eligibility
18 Years to 75 Years
Enrollment
329 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
5
States / cities
Blaine, Minnesota • Plymouth, Minnesota • Columbus, Ohio + 2 more
Conditions
Critical Illness, Sleep, Acute Lung Injury, Acute Respiratory Distress Syndrome
Interventions
Dexmedetomidine, Midazolam and Fentanyl
Drug
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 85 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2019
U.S. locations
2
States / cities
Tucson, Arizona
Conditions
Obstructive Sleep Apnea, Obesity Hypoventilation Syndrome (OHS), Chronic Obstructive Pulmonary Disease (COPD), Neuromuscular Diseases (NMD)
Interventions
Non-Invasive Ventilation
Device
Lead sponsor
Breas Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
4
States / cities
Scottsdale, Arizona • San Diego, California • Colorado Springs, Colorado + 1 more
Conditions
Parkinson's Disease, Sleep Disordered Breathing, Sleep Obstructive Apnea
Interventions
Neurocognitive function, Sleep evaluations
Other
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Miami, Florida
Conditions
Sleep Apnea, Obstructive, Sleep Apnea Syndromes, Child Behavior Disorders, Attention Deficit Disorder With Hyperactivity, Disorders of Excessive Somnolence
Interventions
CPAP treatment, No CPAP treatment
Procedure · Other
Lead sponsor
University of Michigan
Other
Eligibility
5 Years to 12 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
Bladder Function
Interventions
cystometry (CMG), polysomnography (PSG)
Procedure
Lead sponsor
Astellas Pharma Inc
Industry
Eligibility
18 Years and older · Female only
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Durham, North Carolina
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Federal Aviation Administration (FAA) National Sleep Study

NCT05035940
Conditions
Noise Exposure
Interventions
Not listed
Lead sponsor
University of Pennsylvania
Other
Eligibility
21 Years and older
Enrollment
401 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Recruiting No phase listed Observational Accepts healthy volunteers

Neuroplasticity in RBD

NCT05471960
Conditions
REM Sleep Behavior Disorder
Interventions
Natural progression over time
Other
Lead sponsor
University of Minnesota
Other
Eligibility
21 Years to 75 Years
Enrollment
86 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Conditions
Obstructive Sleep Apnea, Chronic Obstructive Pulmonary Disease
Interventions
Continuous Positive Airway Pressure
Device
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Fontana, California
Recruiting Phase 4 Interventional Accepts healthy volunteers

Sleep Apnea in Elderly

NCT02703220
Conditions
Sleep Apnea, Elderly Adults
Interventions
Hyperoxia/oxygen, Acetazolamide, Finasteride
Other · Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
60 Years to 89 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2027
U.S. locations
1
States / cities
Detroit, Michigan
Conditions
Primary Insomnia
Interventions
Eplivanserin, Placebo
Drug
Lead sponsor
Sanofi
Industry
Eligibility
18 Years and older
Enrollment
637 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Bridgewater, New Jersey
Conditions
Amyotrophic Lateral Sclerosis (ALS)
Interventions
Sleep study-guided adjustment of NIV, Standard initiation of NIV
Other
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 80 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
New York, New York
Conditions
Transient Ischemic Attack, Stroke
Interventions
Standard CPAP Intervention, Enhanced CPAP Intervention
Device · Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
255 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
2
States / cities
New Haven, Connecticut • Indianapolis, Indiana
Conditions
Restless Legs Syndrome
Interventions
Topiramate
Drug
Lead sponsor
Neurocare
Other
Eligibility
18 Years to 70 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2005
U.S. locations
1
States / cities
Newton, Massachusetts