Independent directory Public ClinicalTrials.gov records United States
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Showing 217–240 of 438 matching trials from the live ClinicalTrials.gov search.
Conditions
Oral Health
Interventions
Oral probiotic, Placebo
Dietary Supplement
Lead sponsor
USANA Health Sciences
Industry
Eligibility
18 Years to 65 Years
Enrollment
105 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
South Jordan, Utah
Completed Not applicable Interventional Accepts healthy volunteers

Feasibility of an Oral Intervention for Sexual Health in Transgender Men

NCT06470906
Conditions
Vaginal Dysbiosis, Vaginal Disease, Molecular-bacterial Vaginosis
Interventions
Probiotic Group, Placebo Group
Dietary Supplement
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 45 Years · Male only
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Brooklyn, New York
Conditions
Clonal Hematopoiesis
Interventions
high-fiber plant-based meals, fermented foods, supplements, surveys
Other · Dietary Supplement
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
7
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more
Conditions
Healthy
Interventions
Probiotic: Bacillus subtilis, Lactobacillus plantarum, Bifidobacterium animalis, Placebo
Dietary Supplement
Lead sponsor
University of Florida
Other
Eligibility
35 Years to 65 Years
Enrollment
155 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Gainesville, Florida
Conditions
Antibiotic-associated Diarrhea, Clostridium Difficile
Interventions
Lactobacillus reuteri
Dietary Supplement
Lead sponsor
Case Western Reserve University
Other
Eligibility
18 Years and older
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2017
U.S. locations
1
States / cities
Cleveland, Ohio
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Randomized Placebo Controlled Pilot Study of Probiotic Supplementation in At-risk Pregnant Women

NCT03646487
Conditions
Iron-deficiency, Pregnancy, High Risk, Stress, Psychological
Interventions
Probiotic LP299v 10x10 colony forming units in capsule form, Placebo in capsule form
Dietary Supplement · Other
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Chicago, Illinois
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of Lactobacillus Rhamnosus GG (LGG) on Infant Colic

NCT01279265
Conditions
Colic, Inflammation
Interventions
Nutramigen with Enflora, Nutramigen A+
Dietary Supplement
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
3 Weeks to 3 Months
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Houston, Texas
Conditions
Gingivitis
Interventions
Probiotics
Other
Lead sponsor
Sunstar Americas
Industry
Eligibility
18 Years to 65 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Cambridge, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers

Use of Probiotics to Aid in Weight Loss

NCT01445704
Conditions
Weight Loss
Interventions
Probiotics, Placebo
Dietary Supplement
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
18 Years and older
Enrollment
151 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Greenville, South Carolina
Conditions
Chronic Rhinosinusitis (Diagnosis)
Interventions
Lactobacillus sakei proBio65, Isotonic Saline Solution
Drug · Other
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Completed Not applicable Interventional Accepts healthy volunteers

Probiotic Intervention Study

NCT06030362
Conditions
Obesity, Food Addiction
Interventions
Probiotic, Placebo
Dietary Supplement
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 50 Years
Enrollment
106 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Older Adults, Bioelectrical Impedance, Appetite Hormones, Metabolic Health, Body Composition Measurement, Cognitive Health
Interventions
Synbiotic supplement
Dietary Supplement
Lead sponsor
Texas Tech University
Other
Eligibility
65 Years and older
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Lubbock, Texas
Conditions
ME/CFS, IBS - Irritable Bowel Syndrome
Interventions
Floradapt Intensive GI, Placebo
Drug · Other
Lead sponsor
Nova Southeastern University
Other
Eligibility
45 Years to 70 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Fort Lauderdale, Florida
Completed Not applicable Interventional Accepts healthy volunteers

Efficacy of Yogurt Containing BB12 in Subjects With GI Symptoms

NCT00618488
Conditions
Pain
Interventions
Probiotic BB12 - Bifidobacterium lactis, Placebo
Dietary Supplement
Lead sponsor
University of North Carolina
Other
Eligibility
18 Years to 70 Years
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Completed Not applicable Interventional Accepts healthy volunteers

Improving the Iron Status of Athletes With Pre-, Pro- and Synbiotics

NCT06021171
Conditions
Iron-deficiency, Iron Deficiency Anemia, Iron Deficiency (Without Anemia)
Interventions
Partially hydrolyzed guar gum + bifidobacterium lactis, Partially hydrolyzed guar gum, Maltodextrin
Dietary Supplement
Lead sponsor
King's College
Other
Eligibility
18 Years to 35 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Wilkes-Barre, Pennsylvania
Conditions
Surgical Wound Infection, Cystitis, Bacteremia, Pneumonia, Enterocolitis, Pseudomembranous
Interventions
Synbiotic 2000
Drug
Lead sponsor
Beth Israel Medical Center
Other
Eligibility
Not listed
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
New York, New York
Conditions
Blood Pressure, Body Composition, Immune Function
Interventions
Synbiotic, Probiotic, Placebo
Dietary Supplement
Lead sponsor
Skidmore College
Other
Eligibility
18 Years to 60 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Saratoga Springs, New York
Completed Not applicable Interventional Accepts healthy volunteers

The Probiotic for Oral Health (PRO Health) Study

NCT03748017
Conditions
Oral Microbiome
Interventions
Placebo-Control Supplement, Streptococcus-Containing Probiotic Supplement
Dietary Supplement
Lead sponsor
University of California, Davis
Other
Eligibility
21 Years to 45 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Davis, California
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of a Probiotic Strain on Ibuprofen-induced GI Damage

NCT04447924
Conditions
Reduction of Small Intestinal Ulceration Risk
Interventions
Bif195, Placebo
Dietary Supplement · Other
Lead sponsor
Chr Hansen
Industry
Eligibility
18 Years to 40 Years
Enrollment
177 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Completed Not applicable Interventional Accepts healthy volunteers

Modulation of Type 1 Diabetes Susceptibility Through the Use of Probiotics

NCT03423589
Conditions
Type1diabetes, Type1 Diabetes Mellitus
Interventions
VSL#3
Dietary Supplement
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
5 Years to 17 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Conditions
Autism Spectrum Disorder
Interventions
intranasal oxytocin, oral probiotics, oral placebo
Drug · Dietary Supplement
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
3 Years to 25 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Charlestown, Massachusetts
Conditions
Oral Health
Interventions
ProBiora3 mints, Placebo tablet
Other
Lead sponsor
Oragenics, Inc.
Industry
Eligibility
18 Years to 35 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2012
U.S. locations
1
States / cities
Seattle, Washington
Active, not recruiting Not applicable Interventional

Probiotics for Inflammation in Pediatric Chronic Pain

NCT05141890
Conditions
Chronic Pain, Body Mass Index >=85th Percentile
Interventions
Lactobacillus Plantarum
Dietary Supplement
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
13 Years to 17 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Completed Not applicable Interventional Accepts healthy volunteers

Probiotic Formula and Infant Growth

NCT01476397
Conditions
Healthy
Interventions
Control infant formula, Test infant formula
Other
Lead sponsor
Société des Produits Nestlé (SPN)
Industry
Eligibility
11 Days to 17 Days
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
8
States / cities
Scottsdale, Arizona • Marietta, Georgia • Bardstown, Kentucky + 5 more