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ClinicalTrials.gov public records Last synced Oct 20, 2026, 5:38 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 112 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: reduced caloric intake Clear all
Withdrawn Not applicable Interventional

Families, Responsibility, Education, Support, and Health for Executive Function

NCT05165511
View directory record Official record
Conditions
Overweight and Obesity, Attention-Deficit Hyperactivity Disorder
Interventions
PBT-EF
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
8 Years to 12 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Oct 20, 2026, 5:38 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effect of Sodium Reduction on Blood Pressure and Physical Function in Older Adults

NCT04074941
View directory record Official record
Conditions
Hypertension, Physical Disability, Aging
Interventions
Dietary intervention
Other
Lead sponsor
Hebrew SeniorLife
Other
Eligibility
60 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Revere, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 11, 2021 · Synced Oct 20, 2026, 5:38 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Study of Serum Markers for Cardiovascular Risk in Obese Youth and Impact of Lifestyle and Medication Intervention

NCT00139477
View directory record Official record
Conditions
Obesity
Interventions
Metformin, Dietary modification with caloric restriction, Establishment of exercise protocol
Drug · Behavioral
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
7 Years to 18 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2011
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 18, 2023 · Synced Oct 20, 2026, 5:38 PM EDT
Completed Not applicable Interventional

PACIFIC: Providing Adults Collaborative Interventions For Ideal Changes

NCT02516839
View directory record Official record
Conditions
Overweight, Obesity
Interventions
Regulation of Cues (ROC), Behavioral Weight Loss (BWL), BWL + ROC, Nutrition Education, Stress Management and Social Support
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 65 Years
Enrollment
271 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Mar 25, 2020 · Synced Oct 20, 2026, 5:38 PM EDT
Completed Not applicable Interventional Results available

Empowered With Movement to Prevent Obesity and Weight Regain

NCT02923674
View directory record Official record
Conditions
Obesity, Weight Loss, Sedentary Lifestyle
Interventions
Weight loss, Exercise, Sitless
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
65 Years to 85 Years
Enrollment
183 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 23, 2022 · Synced Oct 20, 2026, 5:38 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

The CALERIE™ Legacy Study

NCT05651620
View directory record Official record
Conditions
Calorie Restriction
Interventions
Not listed
Lead sponsor
Tufts University
Other
Eligibility
33 Years to 70 Years
Enrollment
216 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
3
States / cities
Baton Rouge, Louisiana • Boston, Massachusetts • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Oct 20, 2026, 5:38 PM EDT
Recruiting Not applicable Interventional

Individualized Nutrition to Optimize Preterm Infant Growth and Neurodevelopment

NCT06266455
View directory record Official record
Conditions
Very Preterm Maturity of Infant, Very Low Birth Weight Infant
Interventions
Standardized Fortification, Adjustable Fortification
Dietary Supplement
Lead sponsor
Children's National Research Institute
Other
Eligibility
Up to 4 Weeks
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2034
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jul 11, 2025 · Synced Oct 20, 2026, 5:38 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reducing Dietary Energy Density by Incorporating Vegetables in Order to Decrease Energy Intake

NCT01165086
View directory record Official record
Conditions
Obesity
Interventions
Incorporating vegetables into the diet to reduce energy density
Other
Lead sponsor
Penn State University
Other
Eligibility
20 Years to 45 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 10, 2011 · Synced Oct 20, 2026, 5:38 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Beverage Choice and Lifestyle Modification in Overweight Youth

NCT01662570
View directory record Official record
Conditions
Obesity
Interventions
Beverage Choice and Lifestyle Modification, Nutrition Education (NE)
Behavioral · Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
4 Years to 8 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 15, 2012 · Synced Oct 20, 2026, 5:38 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Leisure Time Activity and Nutrition Program

NCT00656045
View directory record Official record
Conditions
Obesity, Physical Activity
Interventions
Dietary, Physical Activity, TV Watching
Behavioral
Lead sponsor
The University of Tennessee, Knoxville
Other
Eligibility
21 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008
U.S. locations
1
States / cities
Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 5, 2018 · Synced Oct 20, 2026, 5:38 PM EDT
Recruiting Not applicable Interventional

Treating Early Type 2 Diabetes by Reducing Postprandial Glucose Excursions: A Paradigm Shift in Lifestyle Modification

NCT05766735
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Routine Care + Glycemic Excursion Minimization (RC+GEM), Routine Care (RC)
Behavioral · Other
Lead sponsor
Chiara Fabris, PhD
Other
Eligibility
30 Years to 80 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
2
States / cities
Aurora, Colorado • Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 9, 2026 · Synced Oct 20, 2026, 5:38 PM EDT
Completed Not applicable Interventional

Evaluating Hunger Manipulation During Feeding Intervention

NCT05053438
View directory record Official record
Conditions
Feeding Disorders, Feeding and Eating Disorders, Avoidant/Restrictive Food Intake Disorder
Interventions
Intensive Multidisciplinary Feeding Intervention (IMFI)-Standard of Care, Intensive Multidisciplinary Feeding Intervention (IMFI) standard of care + rapid tube weaning
Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Months to 6 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
2
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Nov 28, 2023 · Synced Oct 20, 2026, 5:38 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Caloric Restriction, Exercise, and Glucoregulation in Humans

NCT00777621
View directory record Official record
Conditions
Diabetes
Interventions
Calorie Restriction, Exercise, Calorie Restriction and Exercise
Other
Lead sponsor
St. Louis University
Other
Eligibility
45 Years to 65 Years
Enrollment
69 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2015
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 12, 2016 · Synced Oct 20, 2026, 5:38 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Factors Affecting Caloric Regulation in Human Feeding

NCT00108784
View directory record Official record
Conditions
Obesity
Interventions
Reduced-energy-density diet
Behavioral
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
20 Years to 60 Years · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2004
U.S. locations
1
States / cities
State College, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 13, 2010 · Synced Oct 20, 2026, 5:38 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Lean Living Study

NCT02501889
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Walnut-rich weight loss diet, Standard weight loss diet
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
21 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Oct 26, 2017 · Synced Oct 20, 2026, 5:38 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Reversal of Lipid-Induced Insulin Resistance

NCT02193295
View directory record Official record
Conditions
Insulin Resistance, NAFLD
Interventions
Caloric Restriction
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 90 Years
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2034
U.S. locations
2
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 22, 2026 · Synced Oct 20, 2026, 5:38 PM EDT
Completed Not applicable Interventional

Diabetes Dietary Study- Low Carbohydrate and Low-Fat Diets in Type 2 Diabetes

NCT00795691
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
low-carbohydrate diet, low-fat diet
Behavioral
Lead sponsor
Albert Einstein College of Medicine
Other
Eligibility
18 Years to 65 Years
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jul 12, 2019 · Synced Oct 20, 2026, 5:38 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

How Quickly Can the Effects of Excessive Caloric Intake on Insulin Resistance be Reversed?

NCT02505958
View directory record Official record
Conditions
Obesity
Interventions
high caloric intake, reduced caloric intake
Other
Lead sponsor
Temple University
Other
Eligibility
18 Years to 70 Years
Enrollment
1 participant
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 28, 2022 · Synced Oct 20, 2026, 5:38 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Protein and Polycystic Ovary Syndrome (PCOS)

NCT07158723
View directory record Official record
Conditions
Polycystic Ovary Syndrome (PCOS)
Interventions
Higher protein dietary pattern, Calorie restriction
Other
Lead sponsor
University of Arkansas, Fayetteville
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Fayetteville, Arkansas
Source: ClinicalTrials.gov public record
Updated Sep 8, 2025 · Synced Oct 20, 2026, 5:38 PM EDT
Recruiting Not applicable Interventional

Fasting During Neoadjuvant Chemotherapy in Patient With Epithelial Ovarian Cancer

NCT06386887
View directory record Official record
Conditions
Epithelial Ovarian Cancer
Interventions
Intermittent Fasting, Neoadjuvant chemotherapy
Behavioral · Drug
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Oct 20, 2026, 5:38 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Energy Content and Energy Density of Pre-portioned Entrees

NCT01349023
View directory record Official record
Conditions
Obesity
Interventions
Energy density (ED), Energy content
Other
Lead sponsor
Penn State University
Other
Eligibility
19 Years to 45 Years
Enrollment
73 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 16, 2012 · Synced Oct 20, 2026, 5:38 PM EDT
Terminated Not applicable Interventional

Reducing Insulin, Growth Hormones, and Tumors

NCT03785808
View directory record Official record
Conditions
Diet Modification, Lung Cancer
Interventions
Special Diet Therapy (low-carb), Special Diet Therapy (low-fat), Special Diet Therapy (USDA control)
Behavioral
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 12, 2019 · Synced Oct 20, 2026, 5:38 PM EDT
Completed Not applicable Interventional

Project THRIVE: Evaluating Different Approaches to Dietary Self-Monitoring for Weight Loss

NCT05241353
View directory record Official record
Conditions
Obesity, Overweight
Interventions
Reduced Frequency Self-Monitoring, Full-Frequency Self-Monitoring, Standard Behavioral Treatment
Behavioral
Lead sponsor
Drexel University
Other
Eligibility
18 Years to 75 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 31, 2023 · Synced Oct 20, 2026, 5:38 PM EDT
Completed Not applicable Interventional

The TREND Study: Tapered Reduction in Energy Intake as a Novel Approach to Dieting

NCT02837211
View directory record Official record
Conditions
Obesity
Interventions
Tapered Low Calorie Diet, Traditional Low-Calorie Diet
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 45 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 21, 2018 · Synced Oct 20, 2026, 5:38 PM EDT