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ClinicalTrials.gov public records Last synced Sep 2, 2026, 7:02 AM EDT

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Showing 1–24 of 35 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Critical Illness, Sepsis, Multiple Organ Failure
Interventions
Glutamine, Antioxidants, Glutamine + Antioxidants, Placebo
Other
Lead sponsor
Daren K. Heyland
Other
Eligibility
18 Years and older
Enrollment
1,223 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2012
U.S. locations
5
States / cities
Aurora, Colorado • Louisville, Kentucky • Dayton, Ohio + 2 more
Not listed Early Phase 1 Interventional Accepts healthy volunteers

Colon Cancer Prevention Using Selenium

NCT01211561
Conditions
Prevention of Colorectal Cancer
Interventions
Selenium, selenomethionine, placebo
Drug
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
50 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2016
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Tuberculosis
Interventions
Multivitamins, Placebo
Dietary Supplement · Other
Lead sponsor
Harvard School of Public Health (HSPH)
Other
Eligibility
18 Years and older
Enrollment
876 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2004
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Prostate Cancer
Interventions
selenium, placebo
Dietary Supplement · Other
Lead sponsor
University of Arizona
Other
Eligibility
Up to 85 Years · Male only
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2007
U.S. locations
1
States / cities
Tucson, Arizona
Completed Phase 3 Interventional Accepts healthy volunteers Results available

S0000 Selenium and Vitamin E in Preventing Prostate Cancer

NCT00006392
Conditions
Prostate Cancer
Interventions
Vitamin E, Selenium, Vitamin E placebo, selenium placebo
Drug · Other
Lead sponsor
SWOG Cancer Research Network
Network
Eligibility
50 Years to 120 Years · Male only
Enrollment
35,533 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2012
U.S. locations
13
States / cities
Chicago, Illinois • Joliet, Illinois • Maywood, Illinois + 8 more
Conditions
Asthma
Interventions
Vitamins A, E, C & Selenium, Placebo
Dietary Supplement
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
12 Years to 25 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2016
U.S. locations
1
States / cities
Jacksonville, Florida
Completed Phase 2 Interventional Results available

Alii Supplement Study

NCT07271316
Conditions
Nutrient Deficiency, Happiness, Digestive Health, Vulnerability to Disease, Mood Swings, Energy
Interventions
Alii Supplement
Dietary Supplement
Lead sponsor
Texas Christian University
Other
Eligibility
18 Years to 25 Years · Female only
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Fort Worth, Texas
Completed Phase 1Phase 2 Interventional Results available

Study to Evaluate SPI-1005 in Adults With Meniere's Disease

NCT02603081
Conditions
Meniere's Disease
Interventions
SPI-1005
Drug
Lead sponsor
Sound Pharmaceuticals, Incorporated
Industry
Eligibility
19 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
5
States / cities
Los Angeles, California • New York, New York • Charleston, South Carolina + 1 more
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Dietary Antioxidants on Cardiovascular Risk Factors

NCT00756405
Conditions
Obesity, Hyperlipidemia, Hypertension
Interventions
Antioxidant diet, Antioxidant supplement, Placebo
Behavioral · Dietary Supplement
Lead sponsor
Christopher Gardner
Other
Eligibility
18 Years and older
Enrollment
88 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Stanford, California
Completed Phase 2 Interventional Results available

Males, Antioxidants, and Infertility Trial

NCT02421887
Conditions
Male Infertility
Interventions
Antioxidant Supplement, Placebo
Drug · Other
Lead sponsor
Yale University
Other
Eligibility
18 Years and older · Male only
Enrollment
171 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
10
States / cities
Los Angeles, California • San Francisco, California • Sunnyvale, California + 7 more
Conditions
Diabetes Mellitus, Type 1
Interventions
Antioxidant supplement, Diabetes treatment, Regular Insulin
Dietary Supplement · Other · Drug
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
12 Years to 21 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Jacksonville, Florida
Conditions
Cataract, Macular Degeneration
Interventions
selenium, vitamin E, vitamin E placebo, selenium placebo
Drug
Lead sponsor
SWOG Cancer Research Network
Network
Eligibility
50 Years to 120 Years · Male only
Enrollment
13,475 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Prostate Cancer
Interventions
selenomethionine, finasteride, placebo
Dietary Supplement · Drug · Other
Lead sponsor
Roswell Park Cancer Institute
Other
Eligibility
18 Years and older · Male only
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Buffalo, New York
Conditions
Cirrhosis
Interventions
selenium, placebo
Dietary Supplement
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years and older
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
1
States / cities
Nashville, Tennessee
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

A Study to Assess the Impact of a Nutritional Supplement on Wellbeing and Nutrient Absorption

NCT06749808
Conditions
Nutrition Status
Interventions
Carotenoid Nutritional Supplement, Placebo
Dietary Supplement
Lead sponsor
Pharmanex
Industry
Eligibility
20 Years to 65 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Provo, Utah
Conditions
No Evidence of Disease, Prostate Carcinoma
Interventions
Selenium, Placebo, Laboratory Biomarker Analysis, Pharmacological Study, Methylselenocysteine
Dietary Supplement · Other · Drug
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
40 Years to 80 Years · Male only
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
3
States / cities
Chicago, Illinois • Buffalo, New York • Nashville, Tennessee
Conditions
Tinea Capitis
Interventions
oral griseofulvin, selenium sulfide shampoo 1%, ciclopirox shampoo , ketoconazole shampoo 2%, baby shampoo
Drug
Lead sponsor
Chen, Catherine, M.D.
Other
Eligibility
12 Months to 12 Years
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
1
States / cities
Norfolk, Virginia
Terminated Not applicable Interventional Accepts healthy volunteers

Effect of Selenium Intervention on Inflammation in Older Adults

NCT01289925
Conditions
Inflammation
Interventions
Selenium, Sugar Pill Placebo
Dietary Supplement · Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
70 Years to 110 Years
Enrollment
182 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2012
U.S. locations
1
States / cities
Baltimore, Maryland
Completed No phase listed Observational Accepts healthy volunteers

Prevention of Alzheimer's Disease by Vitamin E and Selenium (PREADVISE)

NCT00040378
Conditions
Alzheimer Disease
Interventions
alphatocopherol, Selenium, Placebo replacement for vitamin E, Placebo replacement for Selenium
Drug
Lead sponsor
Frederick Schmitt
Other
Eligibility
60 Years to 90 Years · Male only
Enrollment
4,246 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2016
U.S. locations
84
States / cities
Birmingham, Alabama • Anchorage, Alaska • Chula Vista, California + 70 more
Conditions
Chronic Obstructive Pulmonary Disease (COPD)
Interventions
Group 1, Group 2
Dietary Supplement
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 70 Years
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
1
States / cities
New York, New York
Conditions
Autistic Disorder
Interventions
B12, Placebo, folate, B complex, vitamin C, cod liver oil, Mineral complex, carnitine
Dietary Supplement
Lead sponsor
Arkansas Children's Hospital Research Institute
Other
Eligibility
3 Years to 7 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2016
U.S. locations
1
States / cities
Little Rock, Arkansas
Conditions
Non-Cystic Acne
Interventions
VitaMedica® Clear Skin Formula capsules, Placebo Capsules
Dietary Supplement · Other
Lead sponsor
Ablon Skin Institute Research Center
Other
Eligibility
18 Years to 40 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Manhattan Beach, California
Conditions
Vitamin D Deficiency
Interventions
Redoxon VI, placebo
Dietary Supplement
Lead sponsor
Oregon State University
Other
Eligibility
55 Years to 75 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Corvallis, Oregon
Completed Not applicable Interventional Accepts healthy volunteers

Influence of Selenium on Prostate Cancer Related Biomarkers

NCT01112449
Conditions
Effect of Selenium on Oxidative Stress in Healthy Men
Interventions
Placebo, selenomethionine, low dose selenized-yeast, high dose selenized-yeast
Other · Dietary Supplement
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
20 Years to 79 Years · Male only
Enrollment
130 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2014
U.S. locations
1
States / cities
Hershey, Pennsylvania