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ClinicalTrials.gov public records Last synced Nov 5, 2026, 6:08 AM EST

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Showing 1–24 of 24 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: selenomethionine Clear all

Conditions: Nutritional Requirements
Interventions: placebo, selenium as L-selenomethionine; Dietary Supplement
Lead sponsor: USDA Grand Forks Human Nutrition Research Center; Federal
Eligibility: 18 Years and older
Enrollment: 262 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2007
U.S. locations: 1
States / cities: Grand Forks, North Dakota

Conditions: Liver Disease
Interventions: 200 µg selenium as selenate, 400 µg selenium as selenate, 200 µg selenium as selenomethionine, Placebo; Dietary Supplement
Lead sponsor: Vanderbilt University; Other
Eligibility: 18 Years and older
Enrollment: 99 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2012
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Hormone Imbalance, Thyroid Hormone Imbalance, Low Energy, Metabolic Symptoms, Unhealthy Eating Habits
Interventions: Hello Burn, Balance Supplement; Dietary Supplement
Lead sponsor: Love Wellness; Industry
Eligibility: 25 Years and older
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025
U.S. locations: 1
States / cities: Las Vegas, Nevada

Conditions: Prostate Cancer
Interventions: selenium, placebo; Drug · Other
Lead sponsor: Roswell Park Cancer Institute; Other
Eligibility: Male only
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2008
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: Prevention of Colorectal Cancer
Interventions: Selenium, selenomethionine, placebo; Drug
Lead sponsor: University of Illinois Chicago; Other
Eligibility: 50 Years and older
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2016
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Lung Cancer
Interventions: selenomethionine, carboplatin, paclitaxel, laboratory biomarker analysis, radiation therapy; Dietary Supplement · Drug · Other + 1 more
Lead sponsor: Roswell Park Cancer Institute; Other
Eligibility: 18 Years to 120 Years
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2010
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: Group 1, Group 2; Dietary Supplement
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 18 Years to 70 Years
Enrollment: 46 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2010
U.S. locations: 1
States / cities: New York, New York

Conditions: Inflammation
Interventions: Selenium, Sugar Pill Placebo; Dietary Supplement · Other
Lead sponsor: Johns Hopkins University; Other
Eligibility: 70 Years to 110 Years
Enrollment: 182 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2012
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Chemotherapeutic Agent Toxicity, Mucositis, Radiation Toxicity, Stage III Squamous Cell Carcinoma of the Hypopharynx, Stage III Squamous Cell Carcinoma of the Larynx, Stage III Squamous Cell Carcinoma of the Lip and Oral Cavity, Stage III Squamous Cell Carcinoma of the Nasopharynx, Stage III Squamous Cell Carcinoma of the Oropharynx, Stage III Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity, Stage IV Squamous Cell Carcinoma of the Hypopharynx, Stage IV Squamous Cell Carcinoma of the Larynx, Stage IV Squamous Cell Carcinoma of the Lip and Oral Cavity, Stage IV Squamous Cell Carcinoma of the Nasopharynx, Stage IV Squamous Cell Carcinoma of the Oropharynx, Stage IV Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity, Xerostomia
Interventions: selenomethionine, placebo, cisplatin, radiation therapy, quality-of-life assessment; Dietary Supplement · Other · Drug + 2 more
Lead sponsor: Roswell Park Cancer Institute; Other
Eligibility: 18 Years and older
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2012
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: Clear Cell Renal Cell Carcinoma, Clear Cell Renal Cell Carcinoma Metastatic
Interventions: Selenomethionine (SLM), Axitinib, Pembrolizumab; Drug
Lead sponsor: Fernando Maciel Barbosa; Other
Eligibility: 18 Years and older
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Lung Cancer
Interventions: placebo, selenium; Other · Drug
Lead sponsor: ECOG-ACRIN Cancer Research Group; Network
Eligibility: 18 Years and older
Enrollment: 1,772 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2000 – 2019
U.S. locations: 515
States / cities: Mobile, Alabama • Phoenix, Arizona • Scottsdale, Arizona + 339 more

Conditions: Prostate Cancer
Interventions: selenomethionine, finasteride, placebo; Dietary Supplement · Drug · Other
Lead sponsor: Roswell Park Cancer Institute; Other
Eligibility: 18 Years and older · Male only
Enrollment: 55 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2012
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: Ulcerative Colitis (UC)
Interventions: Selenium supplementation, Placebo; Drug
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years to 85 Years
Enrollment: 180 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Prostate Cancer
Interventions: Prostate Health Cocktail; Drug
Lead sponsor: University of Southern California; Other
Eligibility: 18 Years and older · Male only
Enrollment: 43 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2014
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Cataract, Macular Degeneration
Interventions: selenium, vitamin E, vitamin E placebo, selenium placebo; Drug
Lead sponsor: SWOG Cancer Research Network; Network
Eligibility: 50 Years to 120 Years · Male only
Enrollment: 13,475 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004 – 2018
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Cirrhosis
Interventions: selenium, placebo; Dietary Supplement
Lead sponsor: Vanderbilt University; Other
Eligibility: 18 Years and older
Enrollment: 99 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2012
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: No Evidence of Disease, Prostate Carcinoma
Interventions: Selenium, Placebo, Laboratory Biomarker Analysis, Pharmacological Study, Methylselenocysteine; Dietary Supplement · Other · Drug
Lead sponsor: National Cancer Institute (NCI); NIH
Eligibility: 40 Years to 80 Years · Male only
Enrollment: 66 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2014
U.S. locations: 3
States / cities: Chicago, Illinois • Buffalo, New York • Nashville, Tennessee

Conditions: Cancer
Interventions: Not listed
Lead sponsor: National Cancer Institute (NCI); NIH
Eligibility: 20 Years to 60 Years
Enrollment: 34 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 1999 – 2010
U.S. locations: 2
States / cities: Beltsville, Maryland • Bethesda, Maryland

Conditions: Prostate Cancer
Interventions: Vitamin E, Selenium, Vitamin E placebo, selenium placebo; Drug · Other
Lead sponsor: SWOG Cancer Research Network; Network
Eligibility: 50 Years to 120 Years · Male only
Enrollment: 35,533 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2001 – 2012
U.S. locations: 13
States / cities: Chicago, Illinois • Joliet, Illinois • Maywood, Illinois + 8 more

Conditions: Colorectal Cancer, Precancerous Condition
Interventions: Vitamin E, Selenium, Vitamin E placebo, selenium placebo; Drug
Lead sponsor: SWOG Cancer Research Network; Network
Eligibility: 50 Years to 120 Years · Male only
Enrollment: 8,094 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2018
U.S. locations: 1
States / cities: Tucson, Arizona

Conditions: Colorectal Cancer
Interventions: selenomethionine, capecitabine, oxaliplatin, laboratory biomarker analysis, pharmacological study, adjuvant therapy, neoadjuvant therapy, therapeutic conventional surgery, radiation therapy; Dietary Supplement · Drug · Other + 2 more
Lead sponsor: Roswell Park Cancer Institute; Other
Eligibility: 18 Years to 75 Years
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: Effect of Selenium on Oxidative Stress in Healthy Men
Interventions: Placebo, selenomethionine, low dose selenized-yeast, high dose selenized-yeast; Other · Dietary Supplement
Lead sponsor: Milton S. Hershey Medical Center; Other
Eligibility: 20 Years to 79 Years · Male only
Enrollment: 130 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2014
U.S. locations: 1
States / cities: Hershey, Pennsylvania

Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: selenium, irinotecan hydrochloride; Dietary Supplement · Drug
Lead sponsor: Roswell Park Cancer Institute; Other
Eligibility: 18 Years and older
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2007
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: Advanced Metastatic Clear Cell Renal Cell Carcinoma (CCRCC)
Interventions: Selenomethionine (SLM), Axitinib; Drug
Lead sponsor: Mohammed Milhem; Other
Eligibility: 18 Years and older
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2025
U.S. locations: 1
States / cities: Iowa City, Iowa

Search by objective public record fields.

Predicting Dietary Selenium Needs to Achieve Target Blood Selenium Levels

Selenium Supplementation of Patients With Cirrhosis

A Clinical Trial to Evaluate the Effects of a Supplement on Symptoms Associated With Hormone Imbalance

Selenium in Treating Patients Who Are Undergoing Brachytherapy for Stage I or Stage II Prostate Cancer

Colon Cancer Prevention Using Selenium

Carboplatin, Paclitaxel, Selenomethionine, and Radiation Therapy in Treating Patients With Stage III Non-Small Cell Lung Cancer That Cannot Be Removed by Surgery

Effect of Supplementary Vitamins on Oxidant Gene Expression in the Lungs of Healthy Smokers

Effect of Selenium Intervention on Inflammation in Older Adults

Selenomethionine in Reducing Mucositis in Patients With Locally Advanced Head and Neck Cancer Who Are Receiving Cisplatin and Radiation Therapy

Seleno-L Methionine (SLM)-Axitinib-Pembrolizumab

Selenium in Preventing Tumor Growth in Patients With Previously Resected Stage I Non-small Cell Lung Cancer

Selenomethionine and Finasteride Before Surgery or Radiation Therapy in Treating Patients With Stage I or Stage II Prostate Cancer

Selenium Supplementation in Moderate-Severely Active Ulcerative Colitis Patients Treated With Advanced Therapies

Herbal Therapy for Treatment of Recurrent Prostate Cancer

S0000B: Vitamin E and/or Selenium in Preventing Cataract and Age-Related Macular Degeneration in Men on SELECT SWOG-S0000

Selenium Supplementation of Patients With Cirrhosis

Se-Methyl-Seleno-L-Cysteine or Selenomethionine in Preventing Prostate Cancer in Healthy Participants

Characterization of the Pharmacokinetics of Oral Selenium Compounds in Humans Before and Following Supplementation

S0000 Selenium and Vitamin E in Preventing Prostate Cancer

S0000D: Effect of Vitamin E and/or Selenium on Colorectal Polyps in Men Enrolled on SELECT Trial SWOG-S0000

Capecitabine, Oxaliplatin, Selenomethionine, and Radiation Therapy in Treating Patients Undergoing Surgery For Newly Diagnosed Stage II or III Rectal Adenocarcinoma

Influence of Selenium on Prostate Cancer Related Biomarkers

Irinotecan and Selenium in Treating Patients With Advanced Solid Tumors

SLM + Axitinib for Clear Cell RCC