- Conditions
- Spinal Cord Injuries
- Interventions
- Acute Intermitted Hypoxia, Massed Practise, Rapael Glove
- Other · Procedure
- Lead sponsor
- Shirley Ryan AbilityLab
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 121 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2026
- U.S. locations
- 3
- States / cities
- Chicago, Illinois • East Hanover, New Jersey
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Showing 25–48
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- Conditions
- Spinal Cord Injury (SCI)
- Interventions
- Daily AIH Block, Sham dAIH Block, Respiratory Strength Training Block, AIH + Strength Training Block
- Other
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 43 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2024
- U.S. locations
- 1
- States / cities
- Jacksonville, Florida
- Conditions
- Spinal Cord Injuries
- Interventions
- SHAM - Intermittent Room Air - room air mixture, AIH - Intermittent Hypoxia - hypoxia air mixture
- Other
- Lead sponsor
- Spaulding Rehabilitation Hospital
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2027
- U.S. locations
- 1
- States / cities
- Cambridge, Massachusetts
- Conditions
- Incomplete Spinal Cord Injury
- Interventions
- Acute Intermittent Hypoxia, SHAM Acute Intermittent Hypoxia
- Other
- Lead sponsor
- University of Colorado, Boulder
- Other
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 56 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2025
- U.S. locations
- 2
- States / cities
- Aurora, Colorado • Boulder, Colorado
- Conditions
- Type 2 Diabetes, Aging
- Interventions
- Intermittent Hypoxia 1 (IH1), Intermittent Hypoxia 2 (IH2), SHAM - normoxia
- Other
- Lead sponsor
- Darren P Casey
- Other
- Eligibility
- 60 Years to 85 Years
- Enrollment
- 80 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2028
- U.S. locations
- 1
- States / cities
- Iowa City, Iowa
- Conditions
- Brain Injuries
- Interventions
- Intermittent hypoxia, Sham hypoxia
- Procedure
- Lead sponsor
- Indiana University
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 35 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2023
- U.S. locations
- 1
- States / cities
- Indianapolis, Indiana
- Conditions
- Spinal Cord Injuries
- Interventions
- Repeated exposure to acute Intermittent Hypoxia (rAIH), Normal Room Air, Upper-limb Training by Research Staff, Lower-limb Training by Research Staff
- Other
- Lead sponsor
- Shirley Ryan AbilityLab
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2025
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Lumbar Disc Disease
- Interventions
- BRTX-100, Saline
- Biological · Drug
- Lead sponsor
- BioRestorative Therapies
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 99 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2027
- U.S. locations
- 19
- States / cities
- Birmingham, Alabama • Santa Monica, California • Walnut Creek, California + 15 more
- Conditions
- Traumatic Brain Injury
- Interventions
- Acute Intermittent Hypoxia (AIH), Task specific Airway Protection Training, Sham AIH
- Other · Behavioral
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 21 Years to 80 Years
- Enrollment
- 5 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2025
- U.S. locations
- 1
- States / cities
- Jacksonville, Florida
- Conditions
- Cervical Spinal Cord Injury
- Interventions
- Acute Intermittent Hypercapnic Hypoxia, Transcutaneous spinal cord stimulation, SHAM Acute Intermittent Hypercapnic Hypoxia, SHAM Transcutaneous spinal cord stimulation
- Other
- Lead sponsor
- Thomas Jefferson University
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 4 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2025
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Healthy
- Interventions
- Acute Intermittent Hypoxia, Sham Acute Intermittent Hypoxia
- Other
- Lead sponsor
- Shirley Ryan AbilityLab
- Other
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 32 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016 – 2026
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Spinal Cord Injuries
- Interventions
- Hypoxia via Hypoxico Hyp-123, Sham via Hypoxico Hyp-123
- Device
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 17 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2020
- U.S. locations
- 2
- States / cities
- Gainesville, Florida • Jacksonville, Florida
- Conditions
- Sensitivity
- Interventions
- Intervention 1, Intervention 2, Intervention 3, Intervention 4 (sham)
- Device
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 18 Years to 40 Years
- Enrollment
- 22 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2020
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
- Conditions
- Resting Metabolic Rate, Appetite, Heart Rate Variability
- Interventions
- Normobaric Hypoxia, Normobaric Normoxia
- Device
- Lead sponsor
- Florida State University
- Other
- Eligibility
- 20 Years to 45 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2021
- U.S. locations
- 1
- States / cities
- Tallahassee, Florida
- Conditions
- Gastrointestinal Injury, Acute Mountain Sickness
- Interventions
- FP, Placebo, High altitude, Sea level
- Dietary Supplement · Other
- Lead sponsor
- United States Army Research Institute of Environmental Medicine
- Federal
- Eligibility
- 17 Years to 39 Years
- Enrollment
- 33 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2022
- U.S. locations
- 1
- States / cities
- Natick, Massachusetts
- Conditions
- Multiple Sclerosis, Multiple Sclerosis, Relapsing-Remitting, Multiple Sclerosis, Secondary Progressive
- Interventions
- Acute Intermittent Hypoxia, Sham Acute Intermittent Hypoxia
- Other
- Lead sponsor
- Shirley Ryan AbilityLab
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 22 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Infant, Newborn, Hypertension, Pulmonary, Persistent Fetal Circulation Syndrome, Pneumonia, Aspiration, Respiratory Distress Syndrome, Newborn, Respiratory Insufficiency
- Interventions
- Inhaled Nitric Oxide, Standard iNO therapy
- Drug
- Lead sponsor
- NICHD Neonatal Research Network
- Network
- Eligibility
- Up to 14 Days
- Enrollment
- 302 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 1998 – 2003
- U.S. locations
- 18
- States / cities
- Birmingham, Alabama • Phoenix, Arizona • Palo Alto, California + 14 more
- Conditions
- Spinal Cord Injuries
- Interventions
- Daily acute intermittent hypoxia, Room air (SHAM), Walking + tSTIM, Walking + Sham transcutaneous spinal stimulation (tSHAM)
- Other
- Lead sponsor
- Spaulding Rehabilitation Hospital
- Other
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2026
- U.S. locations
- 2
- States / cities
- Chicago, Illinois • Cambridge, Massachusetts
- Conditions
- Amyotrophic Lateral Sclerosis (ALS), Neuromuscular Diseases
- Interventions
- Acute Intermittent Hypoxia, Sham Acute Intermittent Hypoxia
- Other
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 21 Years to 75 Years
- Enrollment
- 29 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2023
- U.S. locations
- 2
- States / cities
- Gainesville, Florida
- Conditions
- Sleep Apnea, Spinal Cord Injury
- Interventions
- Acute episodic hypoxia, Supplemental oxygen, Trazodone, Placebo, Sham
- Procedure · Drug
- Lead sponsor
- John D. Dingell VA Medical Center
- Federal
- Eligibility
- 18 Years to 89 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2027
- U.S. locations
- 1
- States / cities
- Detroit, Michigan
- Conditions
- Mild Cognitive Impairment, Memory Impairment
- Interventions
- IHT Treatment, Sham-IHT Control
- Device · Other
- Lead sponsor
- University of North Texas Health Science Center
- Other
- Eligibility
- 55 Years to 79 Years
- Enrollment
- 66 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2026
- U.S. locations
- 1
- States / cities
- Fort Worth, Texas
- Conditions
- Spinal Cord Injuries (SCI)
- Interventions
- Augmented Acute Intermittent Hypoxia (aAIH), Acute Intermittent Hypercapnic-Hypoxia (AIHH), Sham AIH
- Other
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 18 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Jacksonville, Florida
- Conditions
- Spinal Cord Injuries (SCI)
- Interventions
- Sham AIH, Acute Intermittent Hypoxia (AIH) 15, Acute Intermittent Hypoxia (AIH) 23
- Other
- Lead sponsor
- Milap Sandhu
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Healthy Adults, Mechanical Ventilation Dependence, Hypoxia, Exercise Training, Exercise Intolerance, Dietary Supplement, Nitrate Supplementation, Inspiratory Muscle Training
- Interventions
- Respiratory Muscle Training (RMT), Sham Respiratory Muscle Training, Dietary Supplement: Beetroot Juice Concentrate, placebo beverage
- Device · Dietary Supplement
- Lead sponsor
- Embry-Riddle Aeronautical University
- Other
- Eligibility
- 18 Years to 40 Years
- Enrollment
- 80 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2028
- U.S. locations
- 1
- States / cities
- Daytona Beach, Florida