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Showing 1–24 of 33 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: sham omt Clear all
Not yet recruiting Not applicable Interventional

Can a Specific OMT Protocol Influence Patient Pain and Associated Analgesia Use for Primary Headache Disorders?

NCT06546462
View directory record Official record
Conditions
Headache Disorders, Headache, Analgesia, Opioid Use, Osteopathy
Interventions
Osteopathic Manipulative Treatment (OMT), Sham Light touch arm
Other
Lead sponsor
New York Institute of Technology
Other
Eligibility
18 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated Mar 16, 2025 · Synced Sep 9, 2026, 2:02 AM EDT
Recruiting Not applicable Interventional

Osteopathic Manipulative Therapy Effects on Post-Acute Sequelae of COVID-19 (PASC) or Long COVID

NCT06883513
View directory record Official record
Conditions
Long-COVID, PASC, Long COVID Syndrome
Interventions
Osteopathic Manipulative Therapy Long-COVID protocol, Osteopathic Manipulative Therapy NOT Long-COVID treatment protocol
Other
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Mar 18, 2025 · Synced Sep 9, 2026, 2:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Efficacy of Osteopathic Manipulative Treatment (OMT) on the Golf Swing

NCT03241095
View directory record Official record
Conditions
Manipulation, Osteopathic
Interventions
OMT (Osteopathic Manipulative Treatment), Sham intervention
Procedure
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Mankato, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 16, 2020 · Synced Sep 9, 2026, 2:02 AM EDT
Recruiting Not applicable Interventional

Effects of Osteopathic Manipulative Treatment Protocol on Sleep Quality in Parkinson's Disease Subjects

NCT06671600
View directory record Official record
Conditions
Parkinsons Disease, Sleep
Interventions
Osteopathic Manipulative Treatment, Sham (No Treatment)
Procedure
Lead sponsor
New York Institute of Technology
Other
Eligibility
Not listed
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated Jun 28, 2026 · Synced Sep 9, 2026, 2:02 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Investigating the Efficacy of OMT to Recover Olfactory Perception After COVID-19

NCT06766279
View directory record Official record
Conditions
Anosmia
Interventions
Osteopathic Manipulative Treatment, Sham treatment
Procedure
Lead sponsor
Burrell College of Health Sciences
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Las Cruces, New Mexico
Source: ClinicalTrials.gov public record
Updated Jan 8, 2025 · Synced Sep 9, 2026, 2:02 AM EDT
Completed Not applicable Interventional

Osteopathic Manual Treatment for Hemiplegic Shoulder Pain and Upper Extremity Function in Stroke Patients

NCT06098508
View directory record Official record
Conditions
Hemiplegic Shoulder Pain, Osteopathic Manipulative Treatment
Interventions
Osteopathic Manual Treatment, Sham Treatment
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Middleton, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 16, 2025 · Synced Sep 9, 2026, 2:02 AM EDT
Completed Not applicable Interventional

Is Osteopathic Manipulative Treatment (OMT) Beneficial for Elderly Patients Hospitalized With Pneumonia?

NCT00258661
View directory record Official record
Conditions
Pneumonia
Interventions
Osteopathic Manipulative Treatment, Light-touch Treatment
Procedure
Lead sponsor
A.T. Still University of Health Sciences
Other
Eligibility
50 Years and older
Enrollment
406 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
7
States / cities
Mount Clemens, Michigan • Kirksville, Missouri • Stratford, New Jersey + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 3, 2018 · Synced Sep 9, 2026, 2:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Osteopathic Manipulation on Circulating Immune Markers

NCT07622966
View directory record Official record
Conditions
Healthy Adult Participants, Osteopathic Manipulative Treatment (OMT)
Interventions
Osteopathic Manipulative Treatment (OMT), Sham Comparator
Other
Lead sponsor
Edward Via Virginia College of Osteopathic Medicine
Other
Eligibility
18 Years to 70 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Monroe, Louisiana
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Sep 9, 2026, 2:02 AM EDT
Completed Not applicable Interventional

The Effect of OMT on Patients With COPD: Correlating Pulmonary Function Tests With Biochemical Alterations

NCT01582958
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease
Interventions
Osteopathic Manipulative Treatment (OMT), sham omt
Procedure · Other
Lead sponsor
Michigan State University
Other
Eligibility
49 Years to 80 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Lansing, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 7, 2015 · Synced Sep 9, 2026, 2:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of Osteopathic Manipulative Treatment and Bio Electro-Magnetic Regulation Therapy on Low Back Pain in Adults.

NCT04704375
View directory record Official record
Conditions
Musculoskeletal Pain
Interventions
Bio Electro-Magnetic Regulation (BEMER) Therapy, OMT (osteopathic manipulative treatment), Light touch
Device · Procedure
Lead sponsor
Lake Erie College of Osteopathic Medicine
Other
Eligibility
18 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Bradenton, Florida
Source: ClinicalTrials.gov public record
Updated Nov 17, 2023 · Synced Sep 9, 2026, 2:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Osteopathic Manipulative Medicine in Pregnancy: Physiologic and Clinical Effects

NCT00426244
View directory record Official record
Conditions
Low Back Pain, Pregnancy
Interventions
Osteopathic Manipulative Treatment, Placebo Ultrasound
Other
Lead sponsor
University of North Texas Health Science Center
Other
Eligibility
18 Years to 35 Years · Female only
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2011
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Aug 20, 2018 · Synced Sep 9, 2026, 2:02 AM EDT
Not listed Not applicable Interventional

Osteopathic Manipulation in Breastfed Newborns

NCT03945474
View directory record Official record
Conditions
Osteopathic Medicine, Breast Feeding
Interventions
Sham, Osteopathic Manipulation, OMT
Other
Lead sponsor
Methodist Medical Center of Illinois
Other
Eligibility
20 Hours to 2 Weeks
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
2
States / cities
Peoria, Illinois
Source: ClinicalTrials.gov public record
Updated May 9, 2019 · Synced Sep 9, 2026, 2:02 AM EDT
Withdrawn Not applicable Interventional

Osteopathic Manipulative Treatment for Recurrent Mastitis

NCT05132426
View directory record Official record
Conditions
Mastitis
Interventions
Osteopathic Manipulative Treatment (OMT)
Procedure
Lead sponsor
Western University of Health Sciences
Other
Eligibility
18 Years to 50 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Pomona, California
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Sep 9, 2026, 2:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Osteopathic Manipulative Therapy Effects on Prolonged Post-COVID Olfactory Dysfunction

NCT05112887
View directory record Official record
Conditions
COVID-19 Lower Respiratory Infection, SARS-CoV2 Infection
Interventions
Osteopathic Manipulative Therapy
Other
Lead sponsor
Ohio University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Dublin, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 8, 2021 · Synced Sep 9, 2026, 2:02 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Optimizing Lymphatic Pumping for Influenza Vaccine Responses in Vulnerable Populations

NCT07786467
View directory record Official record
Conditions
No Disease or Condition is Being Directly Studied, The Focus of the Study in Healthy Volunteers
Interventions
Osteopathic manipulation, Sham
Other
Lead sponsor
Lake Erie College of Osteopathic Medicine
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Erie, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Sep 9, 2026, 2:02 AM EDT
Completed Not applicable Interventional

Preventative Osteopathic Manipulative Treatment (OMT) and the Nursing Home Patient

NCT01000142
View directory record Official record
Conditions
General Health Status
Interventions
Osteopathic Manipulative Treatment, Light Touch
Procedure
Lead sponsor
A.T. Still University of Health Sciences
Other
Eligibility
65 Years to 100 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
2
States / cities
Kirksville, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 27, 2018 · Synced Sep 9, 2026, 2:02 AM EDT
Completed Not applicable Interventional

Effects of Osteopathic Manipulative Therapy on Arrhythmias

NCT04004741
View directory record Official record
Conditions
Cardiac Arrhythmia
Interventions
Osteopathic Manipulative Treatment, Light Touch Therapy
Procedure
Lead sponsor
New York Institute of Technology
Other
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Glen Head, New York
Source: ClinicalTrials.gov public record
Updated Apr 5, 2023 · Synced Sep 9, 2026, 2:02 AM EDT
Terminated Not applicable Interventional

OMT of Somatic Dysfunction and Chronic Low Back Pain in Patients With Type 2 Diabetes Mellitus

NCT02054650
View directory record Official record
Conditions
Chronic Low Back Pain, Type 2 Diabetes Mellitus
Interventions
Osteopathic Manual Treatment (OMT), Sham OMT
Other
Lead sponsor
University of North Texas Health Science Center
Other
Eligibility
18 Years to 79 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated May 25, 2016 · Synced Sep 9, 2026, 2:02 AM EDT
Completed Phase 3 Interventional Results available

Osteopathic Health Outcomes in Chronic Low Back Pain (OSTEOPATHIC) Trial

NCT00315120
View directory record Official record
Conditions
Low Back Pain
Interventions
A. Active OMT and active UST, B. Sham OMT and active UST, C. Active OMT and sham UST, D. Sham OMT and sham UST
Procedure
Lead sponsor
University of North Texas Health Science Center
Other
Eligibility
21 Years to 69 Years
Enrollment
455 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Jul 5, 2016 · Synced Sep 9, 2026, 2:02 AM EDT
Not listed Not applicable Interventional

Diabetes and Osteopathic Manipulative Medicine (OMM)

NCT03663322
View directory record Official record
Conditions
Type2 Diabetes Mellitus, Osteopathy in Diseases Classified Elsewhere
Interventions
OMT Protocol, OMT-Sham Protocol
Procedure
Lead sponsor
New York Institute of Technology
Other
Eligibility
30 Years to 90 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
2
States / cities
Central Islip, New York • Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated May 1, 2022 · Synced Sep 9, 2026, 2:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of OMT on Functional Outcomes and Anti-inflammatory Biomarkers in Mild to Moderate Traumatic Brain Injury

NCT03163901
View directory record Official record
Conditions
Vestibular Disorder, Headache, Traumatic Brain Injury
Interventions
Osteopathic Manipulative Treatment
Other
Lead sponsor
Michigan State University
Other
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Mason, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 23, 2020 · Synced Sep 9, 2026, 2:02 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Will the Use of Osteopathic Manipulative Treatments Help Alleviate Headache Pain

NCT01704625
View directory record Official record
Conditions
Headache
Interventions
Osteopathic Manipulative Treatment, Sham Osteopathic Manipulative Treatment
Procedure
Lead sponsor
Good Samaritan Hospital Medical Center, New York
Other
Eligibility
21 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
1
States / cities
West Islip, New York
Source: ClinicalTrials.gov public record
Updated Oct 10, 2012 · Synced Sep 9, 2026, 2:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Preliminary Evaluation of an Osteopathic Manipulative Treatment (OMT) to Prevent Motion Sickness Symptoms

NCT05611814
View directory record Official record
Conditions
Motion Sickness
Interventions
Osteopathic Manipulative Treatment, Sham treatment
Other
Lead sponsor
United States Army Aeromedical Research Laboratory
Federal
Eligibility
19 Years and older
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Fort Rucker, Alabama
Source: ClinicalTrials.gov public record
Updated Nov 9, 2022 · Synced Sep 9, 2026, 2:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Osteopathic Manipulative Treatment and Its Relationship to Autonomic Nervous System Activity

NCT00516984
View directory record Official record
Conditions
Healthy
Interventions
Placebo, Sham, OMT
Procedure
Lead sponsor
University of Oklahoma
Other
Eligibility
19 Years to 50 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Aug 21, 2008 · Synced Sep 9, 2026, 2:02 AM EDT