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ClinicalTrials.gov public records Last synced Oct 22, 2026, 1:01 AM EDT

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Showing 1–24 of 1,806 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: sham stimulation Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Vagus Nerve Stimulation and Stress Reduction Training for Migraine

NCT03592329
View directory record Official record
Conditions
Migraine
Interventions
Stress Reduction Training A, active tVNS, Stress Reduction Training B, sham tVNS
Behavioral · Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
193 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 25, 2026 · Synced Oct 22, 2026, 1:01 AM EDT
Recruiting Not applicable Interventional

Transcutaneous Auricular Vagus Nerve Stimulation for Insomnia in Survivors of Childhood Acute Lymphoblastic Leukemia

NCT07191119
View directory record Official record
Conditions
Survivor of Childhood Cancer, Insomnia, Acute Lymphoblastic Leukemia (ALL)
Interventions
Soterix tVNS device, Soterix tVNS device (sham programmed), Sleep Quality, Neurocognitive and mental health outcomes
Device · Behavioral
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
20 Years to 50 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 14, 2026 · Synced Oct 22, 2026, 1:01 AM EDT
Completed Not applicable Interventional

Sustained Auricular Nerve Stimulation for PVC Suppression

NCT07093034
View directory record Official record
Conditions
Premature Ventricular Complexes, PVC - Premature Ventricular Contraction, Auricular Vagus Nerve Stimulation
Interventions
Extended nocturnal use of auricular vagus nerve stimulator device
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Aug 7, 2026 · Synced Oct 22, 2026, 1:01 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Vagal Auricular Stimulation for Motion Sickness

NCT07873164
View directory record Official record
Conditions
Chronic Nausea
Interventions
UROStim
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
115 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2027 – 2031
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 16, 2026 · Synced Oct 22, 2026, 1:01 AM EDT
Active, not recruiting Not applicable Interventional

Evaluation of the Safety and Efficacy of a Full-Body Electrostimulation Garment for Individuals With Neurological and Neuromuscular Conditions That Cause Spasticity, Hyperreflexia, and Pain

NCT07132775
View directory record Official record
Conditions
Multiple Sclerosis, Fibromyalgia, Neurologic Disorder, Neuromuscular Disorders
Interventions
Active full-body stimulation, Sham full-body stimulation
Device · Other
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 75 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 20, 2026 · Synced Oct 22, 2026, 1:01 AM EDT
Completed Not applicable Interventional

Efficacy of Sana Treatment in Fibromyalgia

NCT04568798
View directory record Official record
Conditions
Fibromyalgia
Interventions
Sana Sham Device
Device
Lead sponsor
Sana Health
Industry
Eligibility
18 Years to 65 Years
Enrollment
166 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 31, 2022 · Synced Oct 22, 2026, 1:01 AM EDT
Completed Not applicable Interventional

Effects of tDCS Paired With Cognitive Training on Brain Networks Associated With Alcohol Use Disorder in Veterans

NCT04574167
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Active Transcranial Direct Current Stimulation (tDCS), Sham Transcranial Direct Current Stimulation (tDCS)
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
22 Years to 70 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 13, 2026 · Synced Oct 22, 2026, 1:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Theta Burst Stimulation on the Brain, Behavior, and Clinical Symptoms in Adults With Bipolar Disorder

NCT04696471
View directory record Official record
Conditions
Bipolar Disorder
Interventions
Continuous Theta Burst Stimulation (cTBS), Sham Continuous Theta Burst Stimulation (Sham cTBS)
Device
Lead sponsor
Mary Phillips, MD MD (Cantab)
Other
Eligibility
18 Years to 35 Years
Enrollment
146 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Oct 22, 2026, 1:01 AM EDT
Recruiting Not applicable Interventional

Cerebellar Deep Brain Stimulation for Movement Disorders in Cerebral Palsy in Children and Young Adults

NCT06122675
View directory record Official record
Conditions
Dyskinetic Cerebral Palsy, Dystonic Cerebral Palsy
Interventions
DBS
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
7 Years to 25 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 5, 2026 · Synced Oct 22, 2026, 1:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Combining tDCS and Neurorehabilitation to Treat Age-related Deficits of Mobility and Cognition: UPfront Walking Study

NCT03122236
View directory record Official record
Conditions
Mobility Limitation, Cognitive Impairment
Interventions
Neurorehabilitation of Standard Walking, Neurorehabilitation of Complex Walking, Sham Transcranial Direct Current Stimulation (Sham tDCS), Active Transcranial Direct Current Stimulation (Active tDCS)
Behavioral · Device
Lead sponsor
University of Florida
Other
Eligibility
65 Years to 110 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
3
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 14, 2024 · Synced Oct 22, 2026, 1:01 AM EDT
Completed Not applicable Interventional

Neuromodulation of Social Cognitive Circuitry in People With Schizophrenia Spectrum Disorders

NCT04418011
View directory record Official record
Conditions
Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorders
Interventions
Repetitive Transcranial Magnetic Stimulation, Repetitive Transcranial Magnetic Stimulation (Intermittent Theta Burst Stimulation), Repetitive Transcranial Magnetic Stimulation (Sham)
Device
Lead sponsor
Centre for Addiction and Mental Health
Other
Eligibility
18 Years to 55 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
2
States / cities
Catonsville, Maryland • Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Oct 17, 2023 · Synced Oct 22, 2026, 1:01 AM EDT
Completed Not applicable Interventional Results available

Transcranial Direct Current Stimulation Augmented Exposure and Response Prevention for Obsessive-Compulsive Disorder

NCT02329587
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
ERP plus tDCS, ERP plus sham tDCS
Other
Lead sponsor
Butler Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2015
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated May 15, 2018 · Synced Oct 22, 2026, 1:01 AM EDT
Completed Not applicable Interventional Results available

Managing Mild Traumatic Brain Injury Related Headaches With Repetitive Transcranial Magnetic Stimulation

NCT03314584
View directory record Official record
Conditions
Traumatic Brain Injury (TBI)
Interventions
Transcranial Magnetic Stimulation, Sham Transcranial Magnetic Stimulation, Magnetic resonance imaging (MRI)
Device · Diagnostic Test
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
179 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 7, 2025 · Synced Oct 22, 2026, 1:01 AM EDT
Terminated Not applicable Interventional

Reliability of Paired Associative Stimulation-induced Neuroplasticity After Stroke

NCT03861806
View directory record Official record
Conditions
Stroke
Interventions
PAS true, PAS sham
Behavioral
Lead sponsor
Burke Medical Research Institute
Other
Eligibility
19 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
White Plains, New York
Source: ClinicalTrials.gov public record
Updated Nov 21, 2022 · Synced Oct 22, 2026, 1:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of tACS Stimulation on Alpha Oscillations

NCT03178344
View directory record Official record
Conditions
Healthy
Interventions
XCSITE100 Stimulator tACS, XCSITE100 Stimulator Sham
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 26, 2019 · Synced Oct 22, 2026, 1:01 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Transcranial Direct Current Stimulation and Modulation of Affect and Pain

NCT06989749
View directory record Official record
Conditions
We Are Not Studying a Disease or Condition
Interventions
Anodal tDCS, Cathodal tDCS, Sham tDCS
Other
Lead sponsor
Trustees of Dartmouth College
Other
Eligibility
18 Years to 55 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Hanover, New Hampshire
Source: ClinicalTrials.gov public record
Updated Oct 7, 2026 · Synced Oct 22, 2026, 1:01 AM EDT
Not yet recruiting Not applicable Interventional

Lily's Grace Temporal Interference

NCT07520955
View directory record Official record
Conditions
Epilepsy
Interventions
TES-TI, Sham Stimulation, Structural and Functional MRI
Device · Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 75 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 29, 2026 · Synced Oct 22, 2026, 1:01 AM EDT
Terminated Not applicable Interventional Results available

The SNAP Trial: SPRINT® Peripheral Nerve Stimulation for the Treatment of Neuropathic Post-Amputation Pain

NCT03783689
View directory record Official record
Conditions
Neuropathic Pain, Amputation
Interventions
SPRINT Peripheral Nerve Stimulation (PNS) System
Device
Lead sponsor
SPR Therapeutics, Inc.
Industry
Eligibility
21 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
14
States / cities
Phoenix, Arizona • La Jolla, California • Orlando, Florida + 11 more
Source: ClinicalTrials.gov public record
Updated Nov 29, 2023 · Synced Oct 22, 2026, 1:01 AM EDT
Not yet recruiting Phase 1Phase 2 Interventional

Stimulation-based Therapy to Improve Balance in DCM

NCT07298460
View directory record Official record
Conditions
Degenerative Cervical Myelopathy
Interventions
Transcutaneous spinal cord stimulation, Balance and Gait Training
Device · Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
50 Years to 90 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 23, 2025 · Synced Oct 22, 2026, 1:01 AM EDT
Completed Not applicable Interventional Results available

Transcutaneous Electrical Acustimulation (TEA) for Gastroparesis

NCT05362578
View directory record Official record
Conditions
Gastroparesis With Diabetes Mellitus
Interventions
transcutaneous electrical accustimulation at treatment point., transcutaneous electrical accustimulation at sham point.
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 80 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Oct 22, 2026, 1:01 AM EDT
Completed Phase 2 Interventional Results available

Post Stroke Hand Functions: Bilateral Movements and Electrical Stimulation Treatments

NCT00369668
View directory record Official record
Conditions
Cerebrovascular Accident, Hemiplegia
Interventions
Bilateral movements and neuromuscular electrical stimulation, Bilateral movements and sham electrical stimulation
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
44 Years to 86 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 15, 2012 · Synced Oct 22, 2026, 1:01 AM EDT
Completed Not applicable Interventional Results available

Self Cranial Electrical Stimulation (CES) for Pain in Older Adults With Knee Osteoarthritis (Self CES for Knee Pain)

NCT04016259
View directory record Official record
Conditions
Osteo Arthritis Knee
Interventions
Cranial Electrical Stimulation (CES), Sham-CES
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
50 Years to 85 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 16, 2020 · Synced Oct 22, 2026, 1:01 AM EDT
Completed Not applicable Interventional Results available

Combined Effect of Transcranial Direct Current Stimulation (tDCS) and Physical Activity on Gait and Functional Mobility in Participants With Multiple Sclerosis

NCT03658668
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
active tDCS, sham tDCS, Physical Activity (PA)
Device · Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 70 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 16, 2023 · Synced Oct 22, 2026, 1:01 AM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Applying Neuromodulation to Accelerate Training Effects

NCT03224559
View directory record Official record
Conditions
Cognition
Interventions
Transcranial Electrical Stimulation
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 12, 2019 · Synced Oct 22, 2026, 1:01 AM EDT