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ClinicalTrials.gov public records Last synced Oct 30, 2026, 8:12 PM EDT

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Showing 121–143 of 143 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: sleep extension Clear all
Completed Early Phase 1 Interventional Accepts healthy volunteers

Social Determinants of Sleep and Obesity

NCT05698693
View directory record Official record
Conditions
Insufficient Sleep, Physical Inactivity, Sedentary Behavior, Obesity
Interventions
Sleep intervention, Contact Control
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
21 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Oct 30, 2026, 8:12 PM EDT
Withdrawn Not applicable Interventional

Golden Halo, Static Magnetic and Electric Field Device, in Recurrent Glioblastoma

NCT05410301
View directory record Official record
Conditions
Glioblastoma, Recurrent Glioblastoma
Interventions
Static Magnetic and Electric (sBE) device, Lomustine, Bevacizumab
Device · Drug
Lead sponsor
Varun Monga, MD
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Apr 21, 2023 · Synced Oct 30, 2026, 8:12 PM EDT
Terminated Phase 4 Interventional Results available

Cyclobenzaprine Extended Release (ER) for Fibromyalgia

NCT01041495
View directory record Official record
Conditions
Fibromyalgia, Pain, Sleep, Fatigue
Interventions
cyclobenzaprine ER (AMRIX), placebo
Drug
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
18 Years to 65 Years
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Nov 27, 2024 · Synced Oct 30, 2026, 8:12 PM EDT
Completed Not applicable Interventional

The Influence of Cardiorespiratory Fitness on Firefighter Cardiovascular Health Under Exercise Conditions

NCT04514354
View directory record Official record
Conditions
Cardiovascular Diseases, Post-Exercise Hypotension
Interventions
GEST
Behavioral
Lead sponsor
University of Connecticut
Other
Eligibility
21 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 14, 2020 · Synced Oct 30, 2026, 8:12 PM EDT
Completed Not applicable Interventional

Efficacy of Trigeminal Nerve Stimulation for ADHD

NCT05374187
View directory record Official record
Conditions
Attention-Deficit Hyperactivity Disorder
Interventions
Active eTNS, Sham eTNS
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
7 Years to 12 Years
Enrollment
218 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
2
States / cities
Los Angeles, California • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Oct 30, 2026, 8:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Acute Effects of PLT Health Solutions zümXR Extended-Release Caffeine

NCT06441695
View directory record Official record
Conditions
Caffeine, Cognitive Change, Mood, Mood Change
Interventions
xumXR extended release caffeine, immediate release caffeine
Dietary Supplement
Lead sponsor
Applied Science & Performance Institute
Industry
Eligibility
35 Years to 50 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Sep 16, 2025 · Synced Oct 30, 2026, 8:12 PM EDT
Completed Not applicable Interventional Results available

Trigeminal Nerve Stimulation for ADHD

NCT02155608
View directory record Official record
Conditions
Attention Deficit Hyperactivity Disorder (ADHD)
Interventions
Active eTNS, Sham eTNS
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
8 Years to 12 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 2, 2019 · Synced Oct 30, 2026, 8:12 PM EDT
Completed Not applicable Interventional

Extension Family Lifestyle Intervention Project (E-FLIP for Kids)

NCT01820338
View directory record Official record
Conditions
Obesity
Interventions
Behavioral Child Tx Contacts, Behavioral Parent-Tx Contacts, Dietary and Physical Activity Information
Behavioral · Other
Lead sponsor
University of Florida
Other
Eligibility
8 Years to 12 Years
Enrollment
314 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 20, 2015 · Synced Oct 30, 2026, 8:12 PM EDT
Completed Phase 2 Interventional Results available

Sodium Oxybate in Schizophrenia With Insomnia

NCT00594256
View directory record Official record
Conditions
Schizophrenia, Insomnia Related to Schizophrenia (307.42)
Interventions
Sodium Oxybate
Drug
Lead sponsor
Nathan Kline Institute for Psychiatric Research
Other
Eligibility
18 Years to 45 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Orangeburg, New York
Source: ClinicalTrials.gov public record
Updated Feb 8, 2016 · Synced Oct 30, 2026, 8:12 PM EDT
Completed Phase 2 Interventional Results available

Study of Lemborexant for Irregular Sleep-Wake Rhythm Disorder and Mild to Moderate Alzheimer's Disease Dementia

NCT03001557
View directory record Official record
Conditions
Irregular Sleep-Wake Rhythm Disorder
Interventions
Lemborexant 2.5 mg, Lemborexant 5 mg, Lemborexant 10 mg, Lemborexant 15 mg, Lemborexant-matched placebo
Drug
Lead sponsor
Eisai Inc.
Industry
Eligibility
60 Years to 90 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
37
States / cities
Little Rock, Arkansas • Rogers, Arkansas • Costa Mesa, California + 30 more
Source: ClinicalTrials.gov public record
Updated May 17, 2021 · Synced Oct 30, 2026, 8:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Impact of Chronic Circadian Disruption vs. Chronic Sleep Restriction on Metabolism

NCT02171273
View directory record Official record
Conditions
Aging, Sleep Restriction, Circadian Disruption
Interventions
Circadian Disruption, Sleep Restriction, Control
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
21 Years to 70 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 20, 2019 · Synced Oct 30, 2026, 8:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Improving Insulin Resistance and Energy Metabolism Through Sleep Extension in Adolescents

NCT03814512
View directory record Official record
Conditions
Sleep, Diabetes Mellitus, Type 2
Interventions
Extended Sleep Intervention
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
13 Years to 19 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Lafayette, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 1, 2024 · Synced Oct 30, 2026, 8:12 PM EDT
Completed Not applicable Interventional

Effect of Hypoglycemia on Sleep

NCT02687893
View directory record Official record
Conditions
Hypoglycemia
Interventions
Aerobic Exercise, Resistance Exercise
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
21 Years to 45 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 10, 2019 · Synced Oct 30, 2026, 8:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Project REST: Regulation of Eating and Sleep Topography

NCT04057716
View directory record Official record
Conditions
Obesity, Childhood, Binge Eating, Sleep, Self-regulation
Interventions
Sleep restriction, Sleep extension
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
8 Years to 12 Years
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2026
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Oct 30, 2026, 8:12 PM EDT
Completed Phase 4 Interventional Results available

Real World Effectiveness of Combining an Employer-based Weight Management Program With Medication for Chronic Weight Management in Employees With Obesity

NCT03799198
View directory record Official record
Conditions
Obesity
Interventions
Weight Management Program (WMP), Medication for chronic weight management (Rx)
Other · Drug
Lead sponsor
Novo Nordisk A/S
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 14, 2022 · Synced Oct 30, 2026, 8:12 PM EDT
Completed Not applicable Interventional

Preterm Premature Rupture of Membranes (PPROM): Bed Rest Versus Activity Trial

NCT01544387
View directory record Official record
Conditions
Pregnancy, Pre-term Premature Rupture of Membranes
Interventions
Bed Rest, Activity
Other
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
2
States / cities
Elmhurst, New York • New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 28, 2014 · Synced Oct 30, 2026, 8:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mechanisms Underlying the Blood Pressure Lowering Effect of Sleep

NCT03043963
View directory record Official record
Conditions
Hypertension
Interventions
Sleep Extension, Sleep Timing
Behavioral
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
25 Years to 70 Years
Enrollment
270 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 21, 2023 · Synced Oct 30, 2026, 8:12 PM EDT
Active, not recruiting Not applicable Interventional

Therapist-Directed VS Online Therapy for Insomnia Co-Occuring With Sleep Apnea

NCT03109210
View directory record Official record
Conditions
Insomnia, Primary, Sleep Apnea, Obstructive
Interventions
Online Cognitive Behavioral Therapy (OCBT), Therapist-directed Cognitive Behavioral Therapy (TCBT)
Behavioral
Lead sponsor
National Jewish Health
Other
Eligibility
21 Years and older
Enrollment
384 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2026
U.S. locations
2
States / cities
Palo Alto, California • Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 21, 2025 · Synced Oct 30, 2026, 8:12 PM EDT
Completed Phase 3 Interventional Results available

Study to Evaluate the Safety and Efficacy of ABT-712 in Subjects With Moderate to Severe Chronic Low Back Pain (CLBP)

NCT00763321
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
ABT-712, Placebo
Drug
Lead sponsor
AbbVie (prior sponsor, Abbott)
Industry
Eligibility
21 Years to 75 Years
Enrollment
287 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
31
States / cities
Huntsville, Alabama • Burbank, California • San Diego, California + 27 more
Source: ClinicalTrials.gov public record
Updated Feb 6, 2014 · Synced Oct 30, 2026, 8:12 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Medications for Opioid Use Disorder Photosensitive Retinal Ganglion Cell Function, Sleep, and Circadian Rhythms: Implications for Treatment

NCT06104280
View directory record Official record
Conditions
Opioid Use Disorder, Sleep Disturbance
Interventions
Post-Illumination Pupillary Response (PIPR), Polysomnography, Multiple Sleep Latency Test, Ecological Momentary Assessments, Actigraphy, DLMO, Melatonin Suppression Test
Other · Behavioral · Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 80 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Oct 30, 2026, 8:12 PM EDT
Recruiting Not applicable Interventional

Impact of Short and Mistimed Sleep on Adolescents With ADHD: The Adolescent Attention and Circadian Timing Study

NCT07684417
View directory record Official record
Conditions
ADHD
Interventions
Aligned sleep extension, Misaligned sleep extension
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
13 Years to 17 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Oct 30, 2026, 8:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Metabolic Effects of Sleep Extension in People With Obesity

NCT03594994
View directory record Official record
Conditions
Insulin Resistance, Obesity
Interventions
Sleep extension
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
21 Years to 65 Years · Female only
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2024
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 11, 2025 · Synced Oct 30, 2026, 8:12 PM EDT
Terminated Not applicable Interventional

Physical Exercise And Cognitive Engagement Outcomes for Mild Neurocognitive Disorder

NCT03095170
View directory record Official record
Conditions
Mild Cognitive Impairment, Memory Disorders, Mild Dementia, Impaired Cognition, Mild Cognitive Disorder, Amnestic Disorder, Dementia and Amnestic Conditions, Poor Short-term Memory, Memory Impairment, Mild Neurocognitive Disorder
Interventions
Computerized brain fitness training, Yoga, Wellness Education, Support Group (patient and partner), Cognitive Rehabilitation
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
21 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 6, 2022 · Synced Oct 30, 2026, 8:12 PM EDT