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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: sleep restriction Clear all
Terminated Not applicable Interventional

Blood Pressure, Heart Rate Variability & Sleep in Veterans With PTSD

NCT01920451
View directory record Official record
Conditions
Insomnia, Posttraumatic Stress Disorder, Hypertension, Cardiovascular Disease
Interventions
Cognitive-Behavioral Therapy for Insomnia (CBTI)
Behavioral
Lead sponsor
Durham VA Medical Center
Federal
Eligibility
21 Years to 65 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 5, 2014 · Synced Sep 22, 2026, 10:17 AM EDT
Completed Not applicable Interventional

Efficacy of Behavioral Insomnia Treatment for Chronic Migraine

NCT01314651
View directory record Official record
Conditions
Chronic Migraine, Insomnia
Interventions
Stimulus Control and Sleep Restriction, Lifestyle Modification
Behavioral
Lead sponsor
Daniel Riche
Other
Eligibility
18 Years to 65 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
University, Mississippi
Source: ClinicalTrials.gov public record
Updated Apr 23, 2014 · Synced Sep 22, 2026, 10:17 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Acoustic Stimulation During Restricted Sleep After Sleep Deprivation

NCT05309473
View directory record Official record
Conditions
Sleep Deprivation, Sleep Restriction, Acoustic Stimulation, Performance, Alertness
Interventions
Philips SmartSleep Acoustic Stimulation Device, Sham (no Acoustic Stimulation)
Device
Lead sponsor
Walter Reed Army Institute of Research (WRAIR)
Federal
Eligibility
18 Years to 39 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Silver Spring, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 22, 2024 · Synced Sep 22, 2026, 10:17 AM EDT
Completed Not applicable Interventional

Managing Sleep Symptoms and Modifying Mechanisms of Traumatic Stress

NCT01743339
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Depression, Sleep
Interventions
Cognitive Behavioral Therapy, Control
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years to 64 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Apr 26, 2017 · Synced Sep 22, 2026, 10:17 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Hormonal Mechanisms of Sleep Restriction

NCT02256865
View directory record Official record
Conditions
Insulin Resistance
Interventions
Ketoconazole, Hydrocortisone, Testosterone, Placebo for ketoconazole, Placebo for hydrocortisone, Placebo for testosterone
Drug
Lead sponsor
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Other
Eligibility
22 Years to 45 Years · Male only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2023
U.S. locations
1
States / cities
Torrance, California
Source: ClinicalTrials.gov public record
Updated Sep 10, 2025 · Synced Sep 22, 2026, 10:17 AM EDT
Not listed Early Phase 1 Interventional

A Feasibility Study to Evaluate The Effect of the Electronic Patient Visit Assessment On Pain and Quality of Life for Patients With Head and Neck Cancer (HNC)

NCT04502797
View directory record Official record
Conditions
Head and Neck Cancer
Interventions
Electronic Patient Visit Assessment (ePVA)
Behavioral
Lead sponsor
New York University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 2, 2021 · Synced Sep 22, 2026, 10:17 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Sleep and Performance

NCT07608614
View directory record Official record
Conditions
Sleep, Glymphatic System
Interventions
Transcranial Electric Stimulation, Sham Comparator
Device
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 30 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 26, 2026 · Synced Sep 22, 2026, 10:17 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sleep Well for Healthy Brain

NCT04583033
View directory record Official record
Conditions
Poor Quality Sleep
Interventions
Cognitive Behavioral Therapy (CBT)
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
55 Years to 70 Years · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Nov 30, 2023 · Synced Sep 22, 2026, 10:17 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Sleep Restriction and Parental History of Hypertension

NCT06482814
View directory record Official record
Conditions
Hypertension
Interventions
Partial sleep deprivation (sleep restriction), Normal sleep
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 35 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Sep 22, 2026, 10:17 AM EDT
Completed Phase 4 Interventional

Solriamfetol and CBT-I in Patients With Insomnia Disorder

NCT05838430
View directory record Official record
Conditions
Insomnia
Interventions
Solriamfetol 75 MG, Cognitive Behavioral Therapy for Insomnia (CBT-I), Monitoring, Placebo
Drug · Behavioral · Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
25 Years to 60 Years
Enrollment
115 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Sep 22, 2026, 10:17 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Impact of Yo-Yo Sleep on Cardiometabolic Health

NCT05880758
View directory record Official record
Conditions
Cardiometabolic Syndrome, Obesity
Interventions
Intermittent Short Sleep (ISS), Social Jetlag (SJL), Sustained Adequate Sleep (SAS)
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 49 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 17, 2026 · Synced Sep 22, 2026, 10:17 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Metabolic Impact of Time Restricted Feeding

NCT03129581
View directory record Official record
Conditions
Obesity, Diet Modification
Interventions
Dietary Counseling
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 65 Years
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 22, 2022 · Synced Sep 22, 2026, 10:17 AM EDT
Completed Phase 2 Interventional

Mindfulness-Based Approaches to Insomnia

NCT00768781
View directory record Official record
Conditions
Insomnia
Interventions
Mindfulness-Based Stress Reduction, Mindfulness-Based Therapy for Insomnia, Wait-List + Behavioral Therapy for Insomnia
Behavioral
Lead sponsor
Rush University Medical Center
Other
Eligibility
21 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 29, 2013 · Synced Sep 22, 2026, 10:17 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Interaction of Chronic Sleep Restriction and Circadian Misalignment on Sleep and Neuro-cognitive Performance

NCT00438438
View directory record Official record
Conditions
Healthy
Interventions
forced desynchrony protocol with sleep restriction
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 35 Years
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 1, 2011 · Synced Sep 22, 2026, 10:17 AM EDT
Completed Phase 2 Interventional

Sleep and Ventricular Arrhythmias Study

NCT02232204
View directory record Official record
Conditions
Cardiac Arrhythmia, Implantable Defibrillator User, Insomnia
Interventions
CBT for Insomnia in ICD Patients (CBT-I-ICD)
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 4, 2014 · Synced Sep 22, 2026, 10:17 AM EDT
Completed Not applicable Interventional Results available

Sequenced Therapies for Comorbid and Primary Insomnias

NCT01651442
View directory record Official record
Conditions
Insomnia Comorbid to Psychiatric Disorder, Primary Insomnia
Interventions
Behavioral Insomnia Therapy, Zolpidem, Trazodone, Cognitive Therapy
Behavioral · Drug
Lead sponsor
Jack Edinger, PhD
Other
Eligibility
21 Years and older
Enrollment
211 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 28, 2021 · Synced Sep 22, 2026, 10:17 AM EDT
Completed Not applicable Interventional

Optimized Sleep After Brain Injury: Sleep Hygiene Intervention After Traumatic Brain Injury

NCT02838082
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Sleep Hygiene Protocol, Standard of Care
Behavioral
Lead sponsor
Craig Hospital
Other
Eligibility
18 Years to 55 Years · Male only
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Englewood, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 1, 2018 · Synced Sep 22, 2026, 10:17 AM EDT
Completed No phase listed Observational Results available

Enhancing Access to Insomnia (EASI) Care in VA PCMHI Clinics

NCT04350866
View directory record Official record
Conditions
Chronic Insomnia
Interventions
Expert Recommendations for Implementing Change bundle of strategies, Brief Behavioral Treatment for Insomnia
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
277,920 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 11, 2026 · Synced Sep 22, 2026, 10:17 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Feasibility of Insomnia Tracking and Treatment in IBD

NCT04132024
View directory record Official record
Conditions
Inflammatory Bowel Diseases, Insomnia
Interventions
Cognitive Behavioral Therapy for Insomnia (CBT-I)
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
Not listed
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated May 10, 2021 · Synced Sep 22, 2026, 10:17 AM EDT
Completed Not applicable Interventional

Social Media-Based Parenting Program for Women With Postpartum Depressive Symptoms: Impact on Child Development

NCT05400161
View directory record Official record
Conditions
Postpartum Depression, Parenting, Parent-Child Relations, Child Development
Interventions
MoodGym, Social Media-Based Parenting Program
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
18 Years and older · Female only
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 21, 2025 · Synced Sep 22, 2026, 10:17 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study of Cognitive Behavioral Therapy for Insomnia (CBT-I) and Acupuncture for Insomnia and Related Distress Among Cancer Caregivers

NCT03012425
View directory record Official record
Conditions
Insomnia, Related Distress Among Cancer Caregivers
Interventions
Cognitive Behavioral Therapy for Insomnia (CBT-I), Acupuncture, questionnaires, Diurnal Cortisol
Behavioral · Procedure · Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
3
States / cities
Irvine, California • New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 7, 2021 · Synced Sep 22, 2026, 10:17 AM EDT
Completed Not applicable Interventional Results available

Developing and Testing a Spanish-Language Intervention to Reduce Cancer-Related Sleep Disturbance

NCT04101526
View directory record Official record
Conditions
Sleep Disturbance
Interventions
Spanish-language Cognitive-Behavioral Therapy for Insomnia (CBT-I) delivered via videoconference
Behavioral
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Oct 28, 2024 · Synced Sep 22, 2026, 10:17 AM EDT
Recruiting Not applicable Interventional

Effect of Nicotinamide Riboside on Ketosis, Fat Oxidation & Metabolic Rate

NCT06044935
View directory record Official record
Conditions
Overweight, Obesity
Interventions
Standard Diet, Ketogenic Diet, Placebo, Nicotinamide Riboside
Other · Dietary Supplement
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 17, 2026 · Synced Sep 22, 2026, 10:17 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sleep Deprivation and Energy Balance

NCT01334788
View directory record Official record
Conditions
Sleep Deprivation
Interventions
sleep deprivation, Normal sleep
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 11, 2023 · Synced Sep 22, 2026, 10:17 AM EDT