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ClinicalTrials.gov public records Last synced Sep 29, 2026, 11:58 PM EDT

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Showing 25–48 of 738 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: smoking cessation intervention Clear all
Not yet recruiting Phase 2Phase 3 Interventional Accepts healthy volunteers

A Stepped Care Approach to Treating Tobacco Use in Rural Veterans

NCT04501016
View directory record Official record
Conditions
Tobacco Cessation
Interventions
Tailored behavioral counseling, Tobacco cessation pharmacotherapy
Behavioral · Drug
Lead sponsor
Iowa City Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 99 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Aug 6, 2020 · Synced Sep 29, 2026, 11:58 PM EDT
Recruiting Not applicable Interventional

Actívatexto: Advancing Smoking Cessation and Physical Activity Among Latinos

NCT06926608
View directory record Official record
Conditions
Smoking, Smoking Cessation, Physical Inactivity
Interventions
Actívatexto, Decídetexto
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
408 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Sep 18, 2026 · Synced Sep 29, 2026, 11:58 PM EDT
Terminated Phase 2 Interventional Results available

Reducing Tobacco-associated Lung Cancer Risk: A Randomized Clinical Trial of AB-free Kava

NCT05081882
View directory record Official record
Conditions
Smoking
Interventions
Kava, Placebo
Drug
Lead sponsor
University of Florida
Other
Eligibility
21 Years to 99 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Sep 29, 2026, 11:58 PM EDT
Completed Not applicable Interventional Results available

Identifying Effective Treatment for Veterans Unwilling to Quit Smoking

NCT04061720
View directory record Official record
Conditions
Tobacco Dependence, Veterans
Interventions
Enhanced Chronic Care, Standard Care
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
502 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Sep 29, 2026, 11:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Smoking Cessation in Women With Gynecological Conditions

NCT01989923
View directory record Official record
Conditions
Cervical Dysplasia
Interventions
Nicotine Replacement Therapy, Electronic Cigarettes
Other · Device
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Sep 29, 2026, 11:58 PM EDT
Completed Not applicable Interventional Results available

Smoking Cessation Using Motivational Therapy and Varenicline

NCT00701896
View directory record Official record
Conditions
Smoking, HIV Infections
Interventions
Varenicline tartrate, Nicotine Replacement Therapy, Biological Control, Motivational Interview
Drug · Other · Behavioral
Lead sponsor
Philip Diaz
Other
Eligibility
18 Years and older
Enrollment
294 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 15, 2021 · Synced Sep 29, 2026, 11:58 PM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

Smartphone Based Smoking Cessation Intervention

NCT03740490
View directory record Official record
Conditions
Smoking Cessation
Interventions
Smart-T + NRT, QuitGuide + NRT
Combination Product
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years and older
Enrollment
454 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Aug 17, 2025 · Synced Sep 29, 2026, 11:58 PM EDT
Completed Not applicable Interventional

Contingency Management for Smoking Cessation in the Homeless

NCT01736982
View directory record Official record
Conditions
Cigarette Smoking
Interventions
Contingency Management, Standard of Care
Behavioral · Other
Lead sponsor
UConn Health
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
New Britain, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 16, 2018 · Synced Sep 29, 2026, 11:58 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers Results available

Enhancing Panic and Smoking Reduction Treatment With D-Cycloserine

NCT01944423
View directory record Official record
Conditions
Nicotine Addiction, Panic Attack
Interventions
d-cycloserine, Pill Placebo, Nicotine replacement therapy, Panic and Smoking Reduction Treatment
Drug · Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 65 Years
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated May 19, 2021 · Synced Sep 29, 2026, 11:58 PM EDT
Completed Not applicable Interventional Results available

Working Memory Training on Delay Discounting Among Cigarette Smokers

NCT05210608
View directory record Official record
Conditions
Tobacco Use Disorder/Cigarette Smoking
Interventions
Working Memory Training + Behavioral Intervention
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 24, 2025 · Synced Sep 29, 2026, 11:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

In It To Quit: Commitment Contracts for Smoking Cessation

NCT02596061
View directory record Official record
Conditions
Smoking
Interventions
Deposit Contract, Incentives
Behavioral · Other
Lead sponsor
Community Health Center, Inc.
Industry
Eligibility
18 Years and older
Enrollment
311 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Middletown, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 26, 2018 · Synced Sep 29, 2026, 11:58 PM EDT
Completed Not applicable Interventional

Effectiveness of Smoking-cessation Interventions for Urban Hospital Patients

NCT01363245
View directory record Official record
Conditions
Smoking Cessation
Interventions
Telephone Counseling, Fax-to-quit
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
1,618 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 2, 2015 · Synced Sep 29, 2026, 11:58 PM EDT
Completed Not applicable Interventional

Varenicline Tartrate With Telephone-Based Counseling and/or Internet-Based Counseling in Helping Adults Stop Smoking

NCT00301145
View directory record Official record
Conditions
Unspecified Adult Solid Tumor, Protocol Specific
Interventions
smoking cessation intervention, varenicline, counseling intervention, internet-based intervention
Behavioral · Drug · Other
Lead sponsor
SRI International
Industry
Eligibility
18 Years and older
Enrollment
1,200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
3
States / cities
Menlo Park, California • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 19, 2013 · Synced Sep 29, 2026, 11:58 PM EDT
Completed Phase 2 Interventional

Internet-Based Nonsmoking Program for Postpartum Women

NCT02602730
View directory record Official record
Conditions
Cigarette Smoking, Smoking, Tobacco
Interventions
Break the Chain, Clearing the Air
Behavioral
Lead sponsor
Oregon Center for Applied Science, Inc.
Industry
Eligibility
18 Years to 90 Years
Enrollment
307 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 11, 2015 · Synced Sep 29, 2026, 11:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Creating Smokefree Living Together for Chinese Household Pairs

NCT01592682
View directory record Official record
Conditions
Smoking, Smoke Exposure
Interventions
Smokefree counseling
Behavioral
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
410 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 3, 2015 · Synced Sep 29, 2026, 11:58 PM EDT
Recruiting Not applicable Interventional

Refer2Quit: Evaluating a Proactive, Tailored, Population Health Approach for Tobacco Treatment for Household Smokers Through a Pediatric Care Network

NCT06582693
View directory record Official record
Conditions
Smoking, Smoking Cessation, Second Hand Tobacco Smoke
Interventions
Refer2Quit
Other
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
18 Years and older
Enrollment
3,200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Sep 29, 2026, 11:58 PM EDT
Completed Phase 4 Interventional Results available

Evaluation of National Cancer Institute (NCI) Smoking Intervention Resources

NCT01342523
View directory record Official record
Conditions
Smoking Cessation, Smoking, Nicotine Dependence
Interventions
CIS - telephone cessation quitline counseling, Lozenge - nicotine mini-lozenges, Emails - Brief smoking prevention messages, Full website - standard smokefree.gov website content, Lite website - lite version of smokefree.gov, Full mailed booklet - NCI's detailed 36-page quit guide, brief mailed booklet - smaller version of NCI's booklet
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
1,034 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 14, 2015 · Synced Sep 29, 2026, 11:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Enhancing Relapse Prevention for Smoking Cessation With Repetitive Transcranial Magnetic Stimulation

NCT02822703
View directory record Official record
Conditions
Smoking Cessation
Interventions
rTMS Active 20Hz, rTMS Sham
Device
Lead sponsor
The City College of New York
Other
Eligibility
21 Years to 65 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 4, 2016 · Synced Sep 29, 2026, 11:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Parent eReferral to Tobacco Quitline

NCT02997735
View directory record Official record
Conditions
Secondhand Smoke
Interventions
Quitline Delivered Treatment
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
18 Years and older
Enrollment
484 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 28, 2019 · Synced Sep 29, 2026, 11:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Chicago Community Health Study

NCT04460417
View directory record Official record
Conditions
Smoking
Interventions
Enhanced Care, TAU
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
204 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 7, 2020 · Synced Sep 29, 2026, 11:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Twitter-enabled Mobile Messaging for Smoking Relapse Prevention

NCT01602536
View directory record Official record
Conditions
Smoking
Interventions
smoking cessation aides, Twitter
Behavioral
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years to 59 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
2
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Oct 31, 2024 · Synced Sep 29, 2026, 11:58 PM EDT
Completed No phase listed Observational

Couples Dynamics and Smoking Cessation

NCT03885336
View directory record Official record
Conditions
Smoking, Smoking Cessation, Cessation, Smoking, Smoking Behaviors, Smoking, Cigarette
Interventions
No Interventions
Other
Lead sponsor
University of Southern California
Other
Eligibility
18 Years to 65 Years
Enrollment
212 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 20, 2023 · Synced Sep 29, 2026, 11:58 PM EDT
Completed Not applicable Interventional

Use of Technological Advances to Prevent Smoking Relapse Among Smokers With PTSD

NCT01990079
View directory record Official record
Conditions
PTSD, Smoking
Interventions
Bupropion, nicotine replacement therapy, Smoking cessation counseling, mobile contingency management, Stay Quit Coach
Drug · Other · Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 70 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Sep 29, 2026, 11:58 PM EDT
Completed Not applicable Interventional

Effectiveness of an Enhanced Tobacco Intervention Protocol Compared to Standard Treatment in Helping Head and Neck and Lung Cancer Patients Starting Treatment to Reduce Cigarette Use

NCT04694846
View directory record Official record
Conditions
Lung Non-Small Cell Carcinoma, Head and Neck Squamous Cell Carcinoma
Interventions
Nicotine Replacement, Bupropion Hydrochloride Controlled-release, Varenicline, Tobacco Cessation Counseling, Questionnaire Administration, Quality of Life Assessment, Best Practice
Drug · Other
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 9, 2025 · Synced Sep 29, 2026, 11:58 PM EDT