- Conditions
- Metastatic Breast Cancer, Lung Cancer
- Interventions
- Dichloroacetate (DCA)
- Drug
- Lead sponsor
- Jonsson Comprehensive Cancer Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 7 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2011
- U.S. locations
- 1
- States / cities
- Los Angeles, California
Search Results
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Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.
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Showing 1–19
of 19
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Congenital Lactic Acidosis
- Interventions
- Dichloroacetate (DCA), Genetic Marker on Chromosome 14q24.3
- Drug · Genetic
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 21 Years to 50 Years
- Enrollment
- 21 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2009 – 2012
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
- Conditions
- Lactic Acidosis
- Interventions
- Dichloroacetate
- Drug
- Lead sponsor
- National Institute of Environmental Health Sciences (NIEHS)
- NIH
- Eligibility
- 3 Months to 65 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 1994 – 2002
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
- Conditions
- Hyperglycaemia (Diabetic)
- Interventions
- Dichloroacetate, Placebo oral capsule
- Drug
- Lead sponsor
- Yale University
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 21 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2019
- U.S. locations
- 1
- States / cities
- New Haven, Connecticut
- Conditions
- Healthy
- Interventions
- Dichloroacetate (DCA), GSTZ1 haplotyping
- Drug · Other
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 45 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016 – 2017
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
- Conditions
- Diabetes Mellitus, Type 1, Hypoglycemia Unawareness
- Interventions
- Dichloroacetate
- Drug
- Lead sponsor
- Yale University
- Other
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 16 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- New Haven, Connecticut
- Conditions
- Brain Tumor, Glioblastoma
- Interventions
- Dichloroacetate
- Drug
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 21 Years to 90 Years
- Enrollment
- 15 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2014
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
- Conditions
- Mitochondrial Enzyme Deficiencies
- Interventions
- Dichloroacetate
- Drug
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 18 Years to 50 Years · Female only
- Healthy volunteers
- Healthy volunteers not accepted
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
- Conditions
- Head and Neck Cancer, Head and Neck Cancers
- Interventions
- Dichloroacetate, EF5
- Drug · Device
- Lead sponsor
- Daniel T. Chang
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 17 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2016
- U.S. locations
- 1
- States / cities
- Stanford, California
- Conditions
- Healthy
- Interventions
- Dichloroacetate environmental dose, Chloral Hydrate environmental dose, Dichloroacetate therapeutic dose, Chloral Hydrate therapeutic dose
- Drug
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 21 Years to 50 Years
- Enrollment
- 27 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2010 – 2012
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
- Conditions
- Pyruvate Dehydrogenase Complex Deficiency
- Interventions
- Dichloroacetate (DCA), Placebo, Genotype
- Drug · Other · Genetic
- Lead sponsor
- Saol Therapeutics Inc
- Industry
- Eligibility
- 6 Months to 17 Years
- Enrollment
- 34 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2025
- U.S. locations
- 10
- States / cities
- Orange, California • Stanford, California • Washington D.C., District of Columbia + 7 more
- Conditions
- Healthy
- Interventions
- 13C-Pyruvate 13C-lactate and dichloroacetate
- Drug
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 21 Years to 50 Years
- Enrollment
- 5 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2013
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
- Conditions
- MELAS Syndrome
- Interventions
- Dichloroacetate
- Drug
- Lead sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
- NIH
- Eligibility
- 6 Years and older
- Enrollment
- 35 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2000
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Squamous Cell Carcinoma of the Head and Neck
- Interventions
- DCA (dichloroacetate), Placebo
- Drug
- Lead sponsor
- Sanford Health
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2020
- U.S. locations
- 2
- States / cities
- Fargo, North Dakota • Sioux Falls, South Dakota
- Conditions
- Acidosis, Lactic, Chronic Disease
- Interventions
- Nitisinone (NTBC), Dichloroacetate, Low-tyrosin diet
- Drug · Behavioral
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 3 Months to 21 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2001 – 2005
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
- Conditions
- Lactic Acidosis
- Interventions
- sodium dichloroacetate
- Drug
- Lead sponsor
- University of California, San Diego
- Other
- Eligibility
- 3 Months and older
- Enrollment
- 75 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 1998 – 2003
- U.S. locations
- 1
- States / cities
- La Jolla, California
- Conditions
- Healthy
- Interventions
- Dichloroacetate, Genotyping, Leucine, tyrosine
- Drug · Genetic · Other
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 22 Years to 60 Years
- Enrollment
- 2 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2011 – 2012
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
- Conditions
- Neoplasms
- Interventions
- PET Scan, EF5, Carbogen, Dichloroacetate
- Procedure · Drug
- Lead sponsor
- Stanford University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 28 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2015
- U.S. locations
- 1
- States / cities
- Stanford, California
- Conditions
- Glioblastoma Multiforme
- Interventions
- Dichloroacetate (DCA), Genotype
- Drug · Genetic
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2026
- U.S. locations
- 2
- States / cities
- Baltimore, Maryland • Winston-Salem, North Carolina