Independent directory Public ClinicalTrials.gov records United States
Clinical Trials Finder
Objective public record navigation
Search Results

Search by objective public record fields.

Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.

Clear filters
ClinicalTrials.gov public records Last synced Sep 26, 2026, 5:05 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Intervention: sodium fluoride Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Potential of Stannous Fluoride Toothpaste to Reduce Gum Disease

NCT02750943
View directory record Official record
Conditions
Gingivitis
Interventions
Stannous Fluoride, Sodium Monofluorophosphate
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years and older
Enrollment
253 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Oct 25, 2017 · Synced Sep 26, 2026, 5:05 PM EDT
Completed No phase listed Observational

Meta-analysis of Stannous Fluoride and the Effects on Dental Plaque

NCT04006483
View directory record Official record
Conditions
Dental Plaque
Interventions
Stannous fluoride dentifrice, Positive control dentifrice, Negative control dentifrice
Drug
Lead sponsor
Procter and Gamble
Industry
Eligibility
18 Years and older
Enrollment
2,359 participants
Timeline
2018
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 17, 2023 · Synced Sep 26, 2026, 5:05 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Dental Implants and Mouth Rinse

NCT02002442
View directory record Official record
Conditions
Reduction in Bacterial Counts Through the Use of Mouthwash
Interventions
Mouthwash
Other
Lead sponsor
Tufts University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 4, 2018 · Synced Sep 26, 2026, 5:05 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Clinical Efficacy of 10% Arginine Bicarbonate Prophylaxis Paste

NCT01072188
View directory record Official record
Conditions
Hypersensitivity
Interventions
Arginine/Calcium Carbonate, Nupro - Fluoride Free
Device
Lead sponsor
Colgate Palmolive
Industry
Eligibility
18 Years to 70 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008
U.S. locations
1
States / cities
Langhorne, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 13, 2011 · Synced Sep 26, 2026, 5:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparison of Three Toothpastes for the Prevention and Reduction of White Spot Lesions

NCT03440996
View directory record Official record
Conditions
White Spot Lesion, Orthodontic Treatment, Decalcification; Teeth
Interventions
Clinpro™ 5000, Clinpro™ Tooth Crème, MI-Paste Plus
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
12 Years to 60 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Feb 21, 2018 · Synced Sep 26, 2026, 5:05 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Meta-analysis of Stannous Fluoride Dentifrice and the Effects on Dentine Hypersensitivity

NCT04005417
View directory record Official record
Conditions
Dentine Hypersensitivity
Interventions
Stannous fluoride dentifrice, Positive control dentifrice, Negative control dentifrice
Drug
Lead sponsor
Procter and Gamble
Industry
Eligibility
18 Years and older
Enrollment
1,036 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 1, 2019 · Synced Sep 26, 2026, 5:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

In Vivo Comparison of Salivary Fluoride Levels Following the Application of Different 5% NaF Varnishes

NCT01629290
View directory record Official record
Conditions
Dental Caries
Interventions
Enamel Pro, Duraphat, Vanish, Placebo
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 65 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 21, 2017 · Synced Sep 26, 2026, 5:05 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Gingivitis Reduction After Use of 0.45% Stannous Fluoride Toothpaste

NCT06300866
View directory record Official record
Conditions
Gingivitis, Plaque, Dental
Interventions
Test, Control
Drug
Lead sponsor
Colgate Palmolive
Industry
Eligibility
18 Years to 70 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Mar 7, 2024 · Synced Sep 26, 2026, 5:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of a Stannous Fluoride Dentifrice for Control of Oral Malodor

NCT07425509
View directory record Official record
Conditions
Oral Malodor (Halitosis)
Interventions
Sodium Fluoride Dentifrice, Stannous Fluoride Toothpaste (SnF)
Drug
Lead sponsor
Church & Dwight Company, Inc.
Industry
Eligibility
18 Years and older
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Fort Wayne, Indiana
Source: ClinicalTrials.gov public record
Updated Feb 22, 2026 · Synced Sep 26, 2026, 5:05 PM EDT
Withdrawn Not applicable Interventional

Lesion Progression of Approximal Caries After Resin Infiltration

NCT02191943
View directory record Official record
Conditions
Proximal Caries
Interventions
Duraphat, Icon approximal caries infiltration kit
Device
Lead sponsor
DMG Dental Material Gesellschaft mbH
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jan 25, 2015 · Synced Sep 26, 2026, 5:05 PM EDT
Completed Early Phase 1 Interventional

SDF Application in Oral Cancer Patients to Prevent Dental Caries

NCT05403125
View directory record Official record
Conditions
Dental Caries
Interventions
silver diamine fluoride, 38%, Sodium fluoride gel, 5000 PPM
Device
Lead sponsor
Texas A & M University Baylor College Of Dentistry
Other
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 16, 2025 · Synced Sep 26, 2026, 5:05 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Effect of Fluoride in a Dentifrice on Remineralization of Erosive Lesions

NCT01641237
View directory record Official record
Conditions
Enamel Erosion
Interventions
sodium fluoride, no added fluoride in a silica base
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 65 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jul 23, 2014 · Synced Sep 26, 2026, 5:05 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

A Study is to Evaluate a Regimen on Gingivitis Using Traditional and Novel Assessment Methods

NCT07211061
View directory record Official record
Conditions
Gingivitis
Interventions
Stannous Fluoride Dentifrice, Sodium Fluoride Dentifrice, electric toothbrush, Cetylpyridinium Chloride (CPC), manual toothbrush
Drug · Device
Lead sponsor
Procter and Gamble
Industry
Eligibility
18 Years and older
Enrollment
69 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Oct 6, 2025 · Synced Sep 26, 2026, 5:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Powered Toothbrush Versus Manual Toothbrush on Plaque and Gingivitis After a Six-Week Period of Home Use

NCT07691814
View directory record Official record
Conditions
Gingivitis
Interventions
power toothbrush, manual toothbrush
Device
Lead sponsor
Philips Clinical & Medical Affairs Global
Industry
Eligibility
18 Years to 65 Years
Enrollment
104 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Fort Wayne, Indiana
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Sep 26, 2026, 5:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Efficacy and Safety Study of Interproximal Cleaning Modalities on Oral Health

NCT02187016
View directory record Official record
Conditions
Gingivitis
Interventions
AirFloss + BreathRx, AirFloss + Listerine, Dental Floss, Manual Toothbrush
Device
Lead sponsor
Philips Oral Healthcare
Industry
Eligibility
18 Years to 65 Years
Enrollment
290 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Mar 7, 2016 · Synced Sep 26, 2026, 5:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Silver Diamine Fluoride Pilot Study (SDF)

NCT02591147
View directory record Official record
Conditions
Dental Caries
Interventions
Silver Diamine Fluoride 38%, Group 2 (Placebo)
Device
Lead sponsor
Justine Kolker
Other
Eligibility
21 Years to 64 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Mar 13, 2023 · Synced Sep 26, 2026, 5:05 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Efficacy of Eco-Friendly Toothpaste Tablets Versus Conventional Toothpaste Using PI and GI Index

NCT05805865
View directory record Official record
Conditions
Gingival Inflammation
Interventions
Toothpaste Tablet, Conventional Toothpaste
Drug
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Feb 20, 2025 · Synced Sep 26, 2026, 5:05 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Fluoride Varnish Randomized Clinical Trial

NCT00066963
View directory record Official record
Conditions
Dental Caries
Interventions
Fluoride Varnish
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
6 Months to 36 Months
Enrollment
376 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2006
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 8, 2022 · Synced Sep 26, 2026, 5:05 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Evaluate Clinical Research From Commerical Oral Care Products

NCT00759187
View directory record Official record
Conditions
Gingival Diseases
Interventions
Fluoride, Triclosan/Fluoride, Chlorhexidine Gluconate
Drug
Lead sponsor
Colgate Palmolive
Industry
Eligibility
18 Years to 65 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 3, 2010 · Synced Sep 26, 2026, 5:05 PM EDT
Completed Phase 1 Interventional Results available

Highly Conformal, Hypofractionated, Focally Dose Escalated Post-Prostatectomy Radiotherapy

NCT03388619
View directory record Official record
Conditions
Cancer Of Prostate, Prostate Neoplasms, Prostate Cancer, Neoplasms of Prostate, Prostatic Cancer
Interventions
Prostate bed with integrated boost, Prostate bed irradiation only, Whole Body Bone Scan, 18F-NaF PET Imaging, CT, mpMRI, ADT
Radiation · Diagnostic Test · Drug
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years and older · Male only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Sep 26, 2026, 5:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Clinical Investigation Examining Plaque and Gingivitis Connected Toothbrush Compared to Non-Connected Toothbrush

NCT04221334
View directory record Official record
Conditions
Gingivitis, Plaque, Dental
Interventions
Electric Toothbrush, oral health care application
Device · Other
Lead sponsor
Colgate Palmolive
Industry
Eligibility
18 Years to 70 Years
Enrollment
79 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Jan 8, 2020 · Synced Sep 26, 2026, 5:05 PM EDT
Completed Phase 2 Interventional Results available

Combined 18F-NaF/18F-FDG PET/MRI for Detection of Skeletal Metastases

NCT00375830
View directory record Official record
Conditions
Cancer
Interventions
Bone scan, 99mTc-methyl diphosphonate, Positron Emission Tomography (PET) scan, 18F-Fludeoxyglucose (18F-FDG), Computed Tomography (CT) scan, 18F-Sodium Fluoride (18F-NaF), Whole Body Magnetic Resonance Imaging (WB-MRI) scan, Gadopentetate dimeglumine, Gadofosveset, Gadobutrol
Procedure · Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2019
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Dec 11, 2023 · Synced Sep 26, 2026, 5:05 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Evaluate Dental Plaque Benefit of a Preventive Treatment Gel

NCT03546491
View directory record Official record
Conditions
Dental Plaque
Interventions
Preventive Gel, Marketed Control
Drug
Lead sponsor
Procter and Gamble
Industry
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Mason, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 3, 2019 · Synced Sep 26, 2026, 5:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Efficacy of Experimental Gel to Foam Dentifrices in Dental Erosion

NCT01657903
View directory record Official record
Conditions
Dental Erosion, Acid Wear
Interventions
Sodium Fluoride, Potassium nitrate
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 65 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jan 25, 2015 · Synced Sep 26, 2026, 5:05 PM EDT