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ClinicalTrials.gov public records Last synced Oct 22, 2026, 6:41 PM EDT

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Showing 1–24 of 62 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: soft tissue mobilization Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Postural Education or Corrective Exercise on Forward Head Posture

NCT05321654
View directory record Official record
Conditions
Postural; Defect
Interventions
Education for Behavior Modification, Corrective Exercise Program
Behavioral
Lead sponsor
Liberty University
Other
Eligibility
18 Years to 29 Years
Enrollment
79 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Lynchburg, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 11, 2022 · Synced Oct 22, 2026, 6:41 PM EDT
Completed Not applicable Interventional

Specific and Shared Mechanisms Associated With Treatment for Chronic Neck Pain

NCT05940012
View directory record Official record
Conditions
Chronic Neck Pain
Interventions
Manual Therapy
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 18, 2025 · Synced Oct 22, 2026, 6:41 PM EDT
Recruiting Not applicable Interventional

Chiropractic Care for Episodic Migraine

NCT06229834
View directory record Official record
Conditions
Episodic Migraine
Interventions
Chiropractic Care, Headache Health Education
Procedure · Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 26, 2026 · Synced Oct 22, 2026, 6:41 PM EDT
Completed Phase 2 Interventional

Cervical Mobilization vs. Standard Physical Therapy for Chronic Neck Pain

NCT01092715
View directory record Official record
Conditions
Neck Pain
Interventions
Spinal mobilization, Massage, Neck exercises
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
20 Years to 80 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2004
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 25, 2010 · Synced Oct 22, 2026, 6:41 PM EDT
Completed Phase 2 Interventional

Chiropractic and Exercise for Seniors With Neck Pain

NCT00269308
View directory record Official record
Conditions
Neck Pain
Interventions
Chiropractic Manual treatment + home exercise ( procedure+behavior), Supervised rehabilitative exercise + home exercise, Home exercise
Procedure · Behavioral
Lead sponsor
Northwestern Health Sciences University
Other
Eligibility
65 Years and older
Enrollment
241 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
1
States / cities
Bloomington, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 23, 2011 · Synced Oct 22, 2026, 6:41 PM EDT
Not listed Not applicable Interventional

Blood Flow Restriction Exercise in the Treatment of Lateral Epicondylalgia Traditional Treatment

NCT04607356
View directory record Official record
Conditions
Tennis Elbow, Lateral Epicondylitis
Interventions
Blood Flow Restriction (BFR), Evidence-informed care
Device · Other
Lead sponsor
United States Naval Medical Center, San Diego
Federal
Eligibility
18 Years to 65 Years
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Feb 8, 2022 · Synced Oct 22, 2026, 6:41 PM EDT
Completed Not applicable Interventional

A Comparison of Manual Physical Therapy and Corticosteroid Injections for Knee Osteoarthritis

NCT01427153
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Orthopaedic manual physical therapy, Corticosteroid Injection
Procedure
Lead sponsor
Madigan Army Medical Center
Federal
Eligibility
38 Years and older
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
2
States / cities
San Antonio, Texas • Tacoma, Washington
Source: ClinicalTrials.gov public record
Updated Jan 27, 2025 · Synced Oct 22, 2026, 6:41 PM EDT
Completed Not applicable Interventional

Comparing Manipulation, Rehabilitation and Combination of the Two in the Treatment of Knee Osteoarthritis

NCT01188837
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
Full Kinetic Chain Manipulative Therapy, Full Kinetic Chain Rehabilitation, Full Kinetic Chain Manipulative Therapy with Rehabilitation
Other
Lead sponsor
Cleveland Chiropractic College
Other
Eligibility
38 Years to 80 Years
Enrollment
144 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 9, 2012 · Synced Oct 22, 2026, 6:41 PM EDT
Completed Not applicable Interventional

Physical Rehabilitation Evaluation and Optimal Physical Therapy (PRE-OPT)

NCT04225572
View directory record Official record
Conditions
Breast Cancer
Interventions
Physical Therapy: Dependent on Patient's Needs
Behavioral
Lead sponsor
Masonic Cancer Center, University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2025
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Oct 22, 2026, 6:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Instrument Assisted Soft Tissue Mobilization Effect on Blood Flow

NCT04785079
View directory record Official record
Conditions
Asymptomatic Condition
Interventions
Graston Instrument assisted Soft tissue Mobilization
Procedure
Lead sponsor
Florida Gulf Coast University
Other
Eligibility
18 Years to 65 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Fort Myers, Florida
Source: ClinicalTrials.gov public record
Updated Jul 27, 2022 · Synced Oct 22, 2026, 6:41 PM EDT
Completed Not applicable Interventional

Preventative Osteopathic Manipulative Treatment (OMT) and the Nursing Home Patient

NCT01000142
View directory record Official record
Conditions
General Health Status
Interventions
Osteopathic Manipulative Treatment, Light Touch
Procedure
Lead sponsor
A.T. Still University of Health Sciences
Other
Eligibility
65 Years to 100 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
2
States / cities
Kirksville, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 28, 2018 · Synced Oct 22, 2026, 6:41 PM EDT
Withdrawn Not applicable Interventional

Dry Needling and Exercise Versus Traditional Physical Therapy for Biceps Tendinitis

NCT04073212
View directory record Official record
Conditions
Bicep Tendinitis, Biceps; Tenosynovitis, Bicipital Tendinitis, Left Shoulder, Bicipital Tendinitis, Right Shoulder, Bicipital Tendinitis, Unspecified Shoulder, Biceps Tendon Disorder
Interventions
Dry Needling, Heavy Slow Load Exercise, Rotator cuff and scapular stabilization exercise program, Soft tissue mobilization
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 64 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
2
States / cities
Aurora, Colorado • Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 30, 2021 · Synced Oct 22, 2026, 6:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of IASTM and Proprioception

NCT03023943
View directory record Official record
Conditions
Healthy Volunteers
Interventions
Instrument Assisted Soft Tissue Mobilization
Other
Lead sponsor
Youngstown State University
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Youngstown, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 10, 2020 · Synced Oct 22, 2026, 6:41 PM EDT
Not listed Phase 2 Interventional

Comparison of Conservative Methods for the Treatment of Lateral Epicondylitis: A Randomized, Prospective Study

NCT01897259
View directory record Official record
Conditions
Tennis Elbow, Lateral Epicondylitis
Interventions
Placebo Injection, Physical Therapy, Corticosteroid Injections, Prolotherapy
Drug · Behavioral
Lead sponsor
Christine M. Kleinert Institute for Hand and Microsurgery
Other
Eligibility
18 Years to 65 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Jan 25, 2018 · Synced Oct 22, 2026, 6:41 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Rate of Torque Development and Voluntary Quadriceps Activation in Patients With Knee Osteoarthritis: A Quantitative Analysis Before and After a Single Session of Manual Physical Therapy

NCT04234282
View directory record Official record
Conditions
Knee Osteoarthritis, Knee Arthritis, Knee Pain Chronic, Knee Deformity, Knee Pain Swelling, Muscle Weakness, Muscle Weakness Condition, Power
Interventions
Manual Physical Therapy
Procedure
Lead sponsor
Jennifer Moreno Clinic
Other
Eligibility
45 Years to 74 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Fort Sam Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 21, 2020 · Synced Oct 22, 2026, 6:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Exercise Versus Exercise and Instrument-Assisted Soft Tissue Mobilization for Plantar Fasciopathy Treatment

NCT04162262
View directory record Official record
Conditions
Plantar Fascitis
Interventions
Instrumental-assisted soft tissue mobilization (IASTM), High-Load Strength Training, Plantar Flexor and Gastrocnemius Stretching
Other
Lead sponsor
Texas Tech University Health Sciences Center
Other
Eligibility
18 Years to 60 Years
Enrollment
83 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Feb 5, 2021 · Synced Oct 22, 2026, 6:41 PM EDT
Completed Not applicable Interventional

Comparison of Usual Podiatric Care and Early Physical Therapy for Plantar Heel Pain

NCT01865734
View directory record Official record
Conditions
Fasciitis, Plantar
Interventions
Physical therapy after initial podiatry visit, Usual care provided by podiatry
Other
Lead sponsor
Des Moines University
Other
Eligibility
18 Years to 70 Years
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Des Moines, Iowa
Source: ClinicalTrials.gov public record
Updated Jan 22, 2019 · Synced Oct 22, 2026, 6:41 PM EDT
Not yet recruiting Not applicable Interventional

Differences in Mechanistic Measures (Oxytocin and Cortisol) of Therapeutic Alliance Between A Talk-Based Therapy and Soft-Tissue Mobilization in Individuals With Chronic Spinal Pain

NCT06987786
View directory record Official record
Conditions
Spine, Low Back Pain, Neck Pain
Interventions
Massage, Talk-based therapy
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 16, 2026 · Synced Oct 22, 2026, 6:41 PM EDT
Completed Not applicable Interventional

Feasibility of a Physical Therapy Intervention on Older Adults With Hyperkyphosis or Forward Head Posture

NCT04114331
View directory record Official record
Conditions
Pneumonia, COPD, Hyperkyphosis, Postural, Thoracic Kyphosis
Interventions
Manual therapy and exercise
Other
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
50 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 5, 2020 · Synced Oct 22, 2026, 6:41 PM EDT
Withdrawn Not applicable Interventional

BFRT vs Standard PT After Total Knee Arthroplasty

NCT04366336
View directory record Official record
Conditions
Total Knee Arthroplasty
Interventions
Blood Flow Restriction Training, Standard Physical Therapy
Procedure
Lead sponsor
Norton Healthcare
Other
Eligibility
50 Years to 70 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Mar 7, 2022 · Synced Oct 22, 2026, 6:41 PM EDT
Terminated Not applicable Interventional

Astym® Compared Eccentric Exercise for Chronic Mid-substance Achilles Tendinopathy

NCT01902433
View directory record Official record
Conditions
Achilles Tendon Pain
Interventions
Astym
Procedure
Lead sponsor
Emily Slaven, PT, PhD
Other
Eligibility
20 Years to 60 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
2
States / cities
Indianapolis, Indiana • Lehi, Utah
Source: ClinicalTrials.gov public record
Updated Jan 24, 2017 · Synced Oct 22, 2026, 6:41 PM EDT
Completed Not applicable Interventional

Does Physical Therapy Prevent Total Knee Arthroplasty in Patients With End Stage Osteoarthritis

NCT02377102
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Physical Therapy
Procedure
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 14, 2017 · Synced Oct 22, 2026, 6:41 PM EDT
Withdrawn Not applicable Interventional

Effectiveness of Dry Needling and STM on Pain Management for Anterior Cruciate Ligament Reconstruction (ACLR)

NCT03506685
View directory record Official record
Conditions
Pain and Anterior Cruciate Ligament Reconstruction
Interventions
Dry needling and STM
Other
Lead sponsor
Keller Army Community Hospital
Federal
Eligibility
18 Years to 40 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
West Point, New York
Source: ClinicalTrials.gov public record
Updated Sep 23, 2025 · Synced Oct 22, 2026, 6:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Integrated Supported Biopsychosocial Self-Management for Back Related Leg Pain

NCT05022121
View directory record Official record
Conditions
Low Back Pain, Sciatica, Back Related Leg Pain, Pain, Chronic, Intervertebral Disc Displacement
Interventions
Supported Biopsychosocial Self-Management (SBSM), Medical Care
Behavioral · Drug
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
2
States / cities
Minneapolis, Minnesota • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 15, 2024 · Synced Oct 22, 2026, 6:41 PM EDT