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Showing 217–240 of 264 matching trials from the live ClinicalTrials.gov search.
Recruiting Not applicable Interventional

Sleep TO Prevent Post-surgical Pain

NCT06976138
Conditions
Knee Osteoarthristis
Interventions
Cognitive-Behavioral Therapy for Insomnia, Bright Light therapy via the Re-Timer®, Negative Ion exposure via IonMi Device, Sleep / Knee Osteoarthritis Education
Behavioral · Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
60 Years and older
Enrollment
252 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
2
States / cities
Baltimore, Maryland • Chestnut Hill, Massachusetts
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Fatigue in Long-Haul Operations

NCT07761611
Conditions
Alertness, Fatigue, Mood, and Performance, Calorie Restriction and Light Intervention
Interventions
Caloric restriction, Light exposure
Behavioral · Device
Lead sponsor
National Aeronautics and Space Administration (NASA)
Federal
Eligibility
18 Years and older
Enrollment
118 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Mountain View, California
Conditions
Sleep Disturbance, Sleep, Depression, Suicide
Interventions
Sleep Feedback + Psychoeducation, Transdiagnostic Sleep and Circadian Intervention + Bright Light (TSC+), Triple Chronotherapy (TCT+)
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 25 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Inherited Retinal Diseases
Interventions
Low Vision Rehabilitation (LVR), Emotion Regulation Therapy (ERT)
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Ann Arbor, Michigan
Completed Not applicable Interventional Results available

Vivity IOL: Emmetropia Compared to Monovision.

NCT05464732
Conditions
Presbyopia
Interventions
Vivity IOL emmetropia, Vivity IOL monovision
Device
Lead sponsor
Carolina Eyecare Physicians, LLC
Other
Eligibility
50 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Mt. Pleasant, South Carolina
Conditions
Migraine Disorders, Photophobia
Interventions
Investigational Coating
Device
Lead sponsor
University of Utah
Other
Eligibility
7 Years to 18 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Salt Lake City, Utah
Conditions
Amblyopia, Strabismus
Interventions
Patching therapy, Glasses
Behavioral
Lead sponsor
The Cleveland Clinic
Other
Eligibility
6 Months to 90 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Completed Not applicable Interventional Accepts healthy volunteers

VR to Reduce Pain/Anxiety During IV Starts

NCT04942561
Conditions
Radiology
Interventions
Samsung Gear VR, Merge VR
Device
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
10 Years to 21 Years
Enrollment
107 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Sleep Onset Latency
Interventions
Amber Tinted Glasses, Clear Glasses, Smart Lightbulbs
Device
Lead sponsor
University of Arizona
Other
Eligibility
60 Months to 83 Months
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Tucson, Arizona
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Effects of Gunnar Computer Glasses on Viewing Comfort and Performance

NCT02925884
Conditions
Dry Eye, Eye Strain, Visual Acuity, Color Perception
Interventions
Gunnar OTC Glasses
Device
Lead sponsor
Pacific University
Other
Eligibility
18 Years to 42 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
Forest Grove, Oregon
Conditions
End Stage Kidney Disease
Interventions
Social Virtual Reality, Individual Virtual Reality
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
Not listed
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Completed Not applicable Interventional Results available

Magnetic Correction of Eye Lid Paralysis

NCT02988856
Conditions
Blepharoptosis, Lagophthalmos, Facial Paralysis
Interventions
Magnetic lid system
Device
Lead sponsor
Kevin Houston
Other
Eligibility
5 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Ametropia, Refractive Error
Interventions
AVA lenses, Standard lenses
Device
Lead sponsor
Essilor International
Industry
Eligibility
18 Years to 70 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Bloomington, Indiana
Conditions
Fatigue, Sleep Disturbance, Circadian Dysregulation
Interventions
Morning bright light therapy, Dim light
Device
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Buffalo, New York
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Comparison Between Spectacles and Contact Lenses

NCT06905912
Conditions
Photophobia
Interventions
Biomedics55 Premier contact lenses, and Altius Tinted Contact Lenses
Device
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Conditions
Cataract
Interventions
Panoptix Toric
Device
Lead sponsor
Eye Center of North Florida
Other
Eligibility
40 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Panama City, Florida
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Effect of Vision Centers on Access to Eye Care and Eye Health Outcomes

NCT07227714
Conditions
Cataract Surgery, Eye Care, Glasses, Primary Eye Care, Vision Center, Eyecare Visits
Interventions
Establishment of a vision center
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
Not listed
Enrollment
150,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
San Francisco, California
Completed Not applicable Interventional Results available

Clinical Trial of Multi-Periscopic Prism Glasses for Hemianopia

NCT04827147
Conditions
Homonymous Hemianopia
Interventions
Multi-Periscopic Prism (MPP) glasses, Fresnel Peripheral Prism (FPP) glasses
Device
Lead sponsor
Massachusetts Eye and Ear Infirmary
Other
Eligibility
7 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
8
States / cities
Birmingham, Alabama • Denver, Colorado • Palm Springs, Florida + 3 more
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

CYPRESS Efficacy and Safety Study Extension

NCT04947735
Conditions
Juvenile Myopia, Myopia
Interventions
Novel spectacle lens design, Spectacle lenses
Device
Lead sponsor
SightGlass Vision, Inc.
Industry
Eligibility
6 Years to 17 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
11
States / cities
Whittier, California • Longwood, Florida • Pittsburg, Kansas + 8 more
Recruiting Not applicable Interventional Accepts healthy volunteers

Mobility Performance in Daily Activities Among Children Wearing Spectacle Lenses

NCT07229352
Conditions
Myopia, Myopia Progression, Juvenile Myopia
Interventions
Novel spectacle lens design, Spectacle lenses
Device
Lead sponsor
SightGlass Vision, Inc.
Industry
Eligibility
6 Years to 12 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Glendale, Arizona
Completed Not applicable Interventional Accepts healthy volunteers Results available

Use of the Avulux® Lenses as an Aid in Reducing the Impact of Migraine Headaches

NCT04341298
Conditions
Migraine
Interventions
11-point pain scale, Headache diary, Avulux®, Sham Avulux®
Other · Device
Lead sponsor
Avulux, Inc.
Industry
Eligibility
18 Years and older
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
3
States / cities
Minneapolis, Minnesota • Columbus, Ohio
Conditions
Sedentary Time, Cardiovascular Diseases, Prediabetes, Obesity
Interventions
Blue light, Eating, Standing
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
26 Years and older
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Tempe, Arizona
Completed Not applicable Interventional Accepts healthy volunteers Results available

Myopia Assessment of Two Manufacturing Processes

NCT04126057
Conditions
Juvenile Myopia
Interventions
SightGlass Vision DOT Spectacle Lenses
Device
Lead sponsor
SightGlass Vision, Inc.
Industry
Eligibility
6 Years to 14 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
5
States / cities
Longwood, Florida • Pittsburg, Kansas • Raytown, Missouri + 2 more
Conditions
Obese
Interventions
Head up
Procedure
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts