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ClinicalTrials.gov public records Last synced Sep 23, 2026, 8:57 AM EDT

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Showing 1–24 of 154 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: stress biomarkers Clear all
Not listed Phase 1Phase 2 Interventional

Intranasal Neuropeptide Y in Clinical Trial in Level Two Trauma Patients for PTSD and Acute Stress Disorder

NCT04071600
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Stress Disorders, Traumatic, Acute
Interventions
Neuropeptide Y, Placebo
Drug · Other
Lead sponsor
New York Medical College
Other
Eligibility
18 Years to 65 Years
Enrollment
117 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
2
States / cities
Valhalla, New York
Source: ClinicalTrials.gov public record
Updated Aug 27, 2019 · Synced Sep 23, 2026, 8:57 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

The Impact of Heavy Alcohol Use on Saliva and Oral Health

NCT06684483
View directory record Official record
Conditions
Alcohol Use Disorder, Alcohol Dependence
Interventions
Not listed
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
18 Years to 100 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Sep 23, 2026, 8:57 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Study of Blood Samples From Older Patients at High Risk of Developing Prostate Cancer and From Healthy Male Participants

NCT00898274
View directory record Official record
Conditions
Precancerous Condition, Prostate Cancer
Interventions
immunoenzyme technique, laboratory biomarker analysis
Other
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
45 Years to 65 Years · Male only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
3
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 8, 2016 · Synced Sep 23, 2026, 8:57 AM EDT
Recruiting Phase 3 Interventional

Stress Hydrocortisone In Pediatric Septic Shock

NCT03401398
View directory record Official record
Conditions
Septic Shock
Interventions
Hydrocortisone, sodium succinate, Normal saline
Drug
Lead sponsor
Jerry Zimmerman
Other
Eligibility
1 Month to 17 Years
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
18
States / cities
Tucson, Arizona • Los Angeles, California • Oakland, California + 15 more
Source: ClinicalTrials.gov public record
Updated Oct 29, 2025 · Synced Sep 23, 2026, 8:57 AM EDT
Recruiting Not applicable Interventional

A Study of a Novel EEG Neurofeedback System for PTSD Treatment

NCT06770998
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
EEG-neurofeedback training, Sham training
Device
Lead sponsor
Foundation for Atlanta Veterans Education and Research, Inc.
Other
Eligibility
18 Years to 65 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
6
States / cities
Birmingham, Alabama • Decatur, Georgia • Boston, Massachusetts + 3 more
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Sep 23, 2026, 8:57 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Hair Biomarkers Study

NCT07011082
View directory record Official record
Conditions
Healthy
Interventions
Stress preventative measures
Other
Lead sponsor
Stanford University
Other
Eligibility
6 Months to 24 Months
Enrollment
600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jun 23, 2025 · Synced Sep 23, 2026, 8:57 AM EDT
Recruiting No phase listed Observational

Collecting Information About Treatment Results for Patients With Cushing's Syndrome

NCT03364803
View directory record Official record
Conditions
Cushing's Disease, Cushing Syndrome, Cushing Disease
Interventions
Cushing's QoL (Quality of Life Questionnaire), Nottingham Health Profile (NHP), Hospital Anxiety and Depression Scale (HADS), Perceived Stress Scale (PSS), Barratt's Impulsivity Scale (BIS), Beck Depression Inventory (BDI), State-Trait Anxiety Inventory (STAI), State Food Craving Questionnaire-State (FCQ-S), Trait Food Craving Questionnaire-Trait (FCQ-T), Visual Analogue Scale (VAS), Sensitivity to Reinforcement of Addictive and other Primary Rewards (STRAP-R) food variant
Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
14 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2026
U.S. locations
7
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more
Source: ClinicalTrials.gov public record
Updated Oct 22, 2025 · Synced Sep 23, 2026, 8:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of XSurge Supplementation on Biomarkers and Performance From High Intensity Resistance Exercise

NCT02442245
View directory record Official record
Conditions
Exercise Performance Recovery
Interventions
XSurge, Placebo: Microcrystalline Cellulose, Control: No supplementation
Dietary Supplement · Other
Lead sponsor
Kemin Foods LC
Industry
Eligibility
18 Years to 35 Years · Male only
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Jan 30, 2018 · Synced Sep 23, 2026, 8:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Acute Effects of Grape Seed Extract on Insulin Sensitivity and Oxidative Stress and Inflammation Markers.

NCT01995643
View directory record Official record
Conditions
Polyphenolic Compounds and Metabolism
Interventions
Active Capsule, Placebo Capsule
Dietary Supplement
Lead sponsor
Clinical Nutrition Research Center, Illinois Institute of Technology
Industry
Eligibility
20 Years to 65 Years
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 26, 2021 · Synced Sep 23, 2026, 8:57 AM EDT
Completed Not applicable Interventional

Improving Age-Related Cognitive Decline With Exercise in Hypertensive Older Adults

NCT05043454
View directory record Official record
Conditions
Hypertension
Interventions
High Intensity Interval Training (HIIT) Exercise
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
55 Years to 75 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Sep 23, 2026, 8:57 AM EDT
Completed Not applicable Interventional Results available

A Biomarker Stress Test for Detection of Early Osteoarthritis

NCT02593864
View directory record Official record
Conditions
Osteoarthritis
Interventions
Variable-Stiffness Shoe
Device
Lead sponsor
VA Palo Alto Health Care System
Federal
Eligibility
18 Years to 80 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Nov 19, 2020 · Synced Sep 23, 2026, 8:57 AM EDT
Recruiting Not applicable Interventional

Virtual Reality vs. Music Relaxation for Reducing Anxiety and Pain During Breast Biopsies

NCT07310004
View directory record Official record
Conditions
Breast Biopsy, Anxiety, Pain
Interventions
Virtual Reality (VR) Mindful App, Standard Calming Music
Other
Lead sponsor
Jonsson Comprehensive Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced Sep 23, 2026, 8:57 AM EDT
Recruiting Not applicable Interventional

The Multicenter Stress Cardiac Magnetic Resonance Quantitative Perfusion Imaging in the United States Study

NCT06854458
View directory record Official record
Conditions
Ischemic Heart Disease (IHD), Cardiac Magnetic Resonance Imaging, Myocardial Blood Flow
Interventions
Quantitative Myocardial Blood Flow Evaluation, Qualitative Myocardial Blood Flow Evaluation, Gadavist, Vasodilator, Blood draw for the laboratory assessment
Diagnostic Test · Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
35 Years to 85 Years
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
13
States / cities
San Francisco, California • Louisville, Kentucky • Boston, Massachusetts + 9 more
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Sep 23, 2026, 8:57 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers Results available

Developing a Virtual Stress Management Intervention for Spousal/Partnered Caregivers of Solid Tumor Cancer Patients.

NCT04739696
View directory record Official record
Conditions
Breast Cancer, Lung Cancer, Colon Cancer, Solid Tumor, Adult
Interventions
PEPRR, Pep-Pal
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 64 Years
Enrollment
538 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Sep 23, 2026, 8:57 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Identification of Biomarkers for Stress Vulnerability and Resilience

NCT05498207
View directory record Official record
Conditions
Healthy
Interventions
Maya App
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 22 Years
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2029
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 22, 2026 · Synced Sep 23, 2026, 8:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reproductive Capacity and Iron Burden in Thalassemia

NCT02308904
View directory record Official record
Conditions
THALASSEMIA MAJOR
Interventions
Blood Draw/Semen Exam, Retrospective data/Chart Review/Relevant Clinical Results, Pituitary MRI
Other
Lead sponsor
UCSF Benioff Children's Hospital Oakland
Other
Eligibility
12 Years and older
Enrollment
59 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2020
U.S. locations
1
States / cities
Oakland, California
Source: ClinicalTrials.gov public record
Updated Dec 22, 2020 · Synced Sep 23, 2026, 8:57 AM EDT
Recruiting Not applicable Interventional

The Prism Conformity Trial for Post-Traumatic Stress Disorder in Adolescents

NCT06854328
View directory record Official record
Conditions
Post-Traumatic Stress Disorder in Adolescence
Interventions
Prism
Device
Lead sponsor
GrayMatters Health Ltd.
Industry
Eligibility
12 Years to 21 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Sep 23, 2026, 8:57 AM EDT
Completed Not applicable Interventional

Feasibility of Telephone Counseling to Increase Physical Fitness in SCI

NCT02225028
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Physical Activity Counseling
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 70 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
2
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 4, 2017 · Synced Sep 23, 2026, 8:57 AM EDT
Recruiting Not applicable Interventional

The Effects of Endotracheal Suctioning on Pain and Serum Markers

NCT06692400
View directory record Official record
Conditions
Intensive Care Unit ICU, Intubation, Critical Illness, Mechanical Ventilation, Pain Measurement, Pain, Procedural, Oxidative Stress, Hypoxia, Biomarkers / Blood, Adult, Uric Acid, Sepsis, COVID, Influenza, Pneumonia
Interventions
endotracheal tube suctioning
Procedure
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Sep 23, 2026, 8:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

An Exploratory Investigation of a Supplement to Promote Brain Health

NCT05520424
View directory record Official record
Conditions
Memory Deficits, Cognitive Change, Stress
Interventions
The Daily Supplement
Dietary Supplement
Lead sponsor
Parable
Industry
Eligibility
30 Years to 60 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Apr 2, 2024 · Synced Sep 23, 2026, 8:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Study on the Effects of VR-3 Herbal Blend Intake on Acute and Chronic Stress in Healthy Adults

NCT00741962
View directory record Official record
Conditions
Healthy Adults
Interventions
VR-3 Herbal Blend, Placebo
Dietary Supplement
Lead sponsor
NEMA Research, Inc.
Industry
Eligibility
35 Years to 45 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Naples, Florida
Source: ClinicalTrials.gov public record
Updated May 11, 2009 · Synced Sep 23, 2026, 8:57 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Effects of Pregnancy-Specific Anxiety on Placental Inflammatory and Oxidative Stress Response and Birth Outcomes

NCT04993742
View directory record Official record
Conditions
Placental Dysfunction, Prenatal Stress
Interventions
MOMS Intervention
Behavioral
Lead sponsor
Henry M. Jackson Foundation for the Advancement of Military Medicine
Other
Eligibility
18 Years and older · Female only
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2026
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Feb 11, 2026 · Synced Sep 23, 2026, 8:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Pilot Randomized Controlled Trial of the Effects of Daily Skin-to-skin Contact (PRCTS2S)

NCT04368767
View directory record Official record
Conditions
Premature Baby 33 to 36 Weeks, Mother-Infant Interaction, Oxidative Stress
Interventions
Skin-to-skin
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
Not listed
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Nov 11, 2020 · Synced Sep 23, 2026, 8:57 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Geospatial Analysis of Neighborhood Environmental Stress in Relation to Biological Markers of Cardiovascular Health and Health Behaviors in Women

NCT04014348
View directory record Official record
Conditions
Cardiovascular (CV) Risk
Interventions
Not listed
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
19 Years to 45 Years · Female only
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Sep 23, 2026, 8:57 AM EDT