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ClinicalTrials.gov public records Last synced Oct 22, 2026, 6:48 AM EDT

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Showing 1–24 of 37 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: substance use module Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Preventing Cigarette Use Among Urban Youth Via an M-Health Primary Care Preventive Intervention

NCT03855410
View directory record Official record
Conditions
Tobacco Use, Drug Use, Adolescent Behavior, Alcohol Use, Sexual Risk Behavior
Interventions
S4E, Attention-Matched Control Group
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
13 Years to 21 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
2
States / cities
Ann Arbor, Michigan • Ypsilanti, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 26, 2019 · Synced Oct 22, 2026, 6:48 AM EDT
Recruiting Not applicable Interventional

Project STRONGER: Stepped Care for Opioid Use Disorder Treatment Engagement and Recovery

NCT07115030
View directory record Official record
Conditions
Opioid Use Disorder, Intimate Partner Violence (IPV), Post Traumatic Stress Disorder PTSD
Interventions
PCT+2HOPE
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older · Female only
Enrollment
532 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
3
States / cities
Bridgeport, Connecticut • Enfield, Connecticut • West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Oct 22, 2026, 6:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

We The Village Family Support Study

NCT04250077
View directory record Official record
Conditions
Community Reinforcement And Family Training, Family Health, Substance-Related Disorders
Interventions
Community Reinforcement And Family Training (CRAFT), We The Village Peer Community Forum
Behavioral
Lead sponsor
We The Village, Inc.
Other
Eligibility
19 Years and older
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced Oct 22, 2026, 6:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Adolescent Screening and Personalized Intervention Resource for Enhancement of Behavioral Health and Substance Use

NCT06306287
View directory record Official record
Conditions
Substance Use, Mental Health Issue
Interventions
ePACE Personalized Intervention, eFACE Fixed Intervention
Behavioral
Lead sponsor
Oregon Research Institute
Other
Eligibility
12 Years and older
Enrollment
132 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Oct 22, 2026, 6:48 AM EDT
Active, not recruiting Not applicable Interventional

Mindfulness and ACL Surgery

NCT05542563
View directory record Official record
Conditions
ACL, ACL Injury
Interventions
Healthy Minds Program (HMP) App
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
16 Years to 40 Years
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Oct 22, 2026, 6:48 AM EDT
Completed Not applicable Interventional

A Novel Person-Centered Treatment Component for Substance Use Treatment

NCT02005367
View directory record Official record
Conditions
Substance Use Disorders, Depression, Bipolar Disorder, Psychosis, Personality Disorders
Interventions
Natural Recovery-Horticulture, Natural Recovery-Art/Music
Behavioral
Lead sponsor
Hampton VA Medical Center
Federal
Eligibility
18 Years to 85 Years
Enrollment
643 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Hampton, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 9, 2013 · Synced Oct 22, 2026, 6:48 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

A Hybrid Program to Prevent Substance Use Risk Among Upper Elementary School Students Using a Positive Youth Development Approach

NCT07162155
View directory record Official record
Conditions
Vaping, E Cig Use, Prescription Drug Misuse
Interventions
School-based Hybrid Intervention to Prevent Vaping and Prescription Drug Misuse
Behavioral
Lead sponsor
Christopher Williams
Industry
Eligibility
7 Years to 11 Years
Enrollment
3,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
White Plains, New York
Source: ClinicalTrials.gov public record
Updated Sep 9, 2025 · Synced Oct 22, 2026, 6:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

CRISOL Contigo: a Multi-level Intervention to Reduce the Disproportionate Toll of COVID-19 Among Latino Communities in Philadelphia.

NCT04646616
View directory record Official record
Conditions
Covid19, Mental Health Issue, Violence
Interventions
Community popular opinion leader (POL) based intervention
Other
Lead sponsor
Drexel University
Other
Eligibility
18 Years and older
Enrollment
178 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 5, 2023 · Synced Oct 22, 2026, 6:48 AM EDT
Completed Not applicable Interventional Results available

Application of Economics & Social Psychology to Improve Opioid Prescribing Safety Trial 1: EHR Nudges

NCT04477304
View directory record Official record
Conditions
Opioid Abuse, Unspecified
Interventions
Opioid Naive, OR, At-risk for long-term use, OR, Long-term opioid recipient
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
555 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 7, 2025 · Synced Oct 22, 2026, 6:48 AM EDT
Recruiting Not applicable Interventional

Brief Motivational Interviewing +/- Mindfulness Training for Adolescent Alcohol Use in Pediatric Primary Care

NCT07059078
View directory record Official record
Conditions
Adolescent Alcohol Use
Interventions
Brief Motivational Interviewing-based Alcohol Intervention, Smartphone App-delivered Mindfulness Training
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
12 Years to 17 Years
Enrollment
1,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
13
States / cities
Baltimore, Maryland • Belcamp, Maryland • Bowie, Maryland + 6 more
Source: ClinicalTrials.gov public record
Updated Sep 11, 2026 · Synced Oct 22, 2026, 6:48 AM EDT
Active, not recruiting Not applicable Interventional

EPI-MINN: Targeting Cognition and Motivation

NCT05112432
View directory record Official record
Conditions
Psychosis
Interventions
Cognitive and Social Cognitive Training, Personalized Real-Time Intervention for Motivational Enhancement (PRIME) App, Early Psychosis Coordinated Specialty Care
Device · Behavioral · Other
Lead sponsor
University of Minnesota
Other
Eligibility
15 Years to 40 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
3
States / cities
Duluth, Minnesota • Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 7, 2026 · Synced Oct 22, 2026, 6:48 AM EDT
Completed Not applicable Interventional

Mindfulness and Hip Preservation Surgery

NCT05335421
View directory record Official record
Conditions
Hip Preservation Surgery
Interventions
Healthy Minds Program (HMP) App
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 45 Years
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 24, 2026 · Synced Oct 22, 2026, 6:48 AM EDT
Not yet recruiting Not applicable Interventional

CBITS-RTM Pilot Study

NCT07682441
View directory record Official record
Conditions
PTSD - Post Traumatic Stress Disorder, Substance Use
Interventions
Adapted Cognitive Behavioral Intervention for Trauma in Schools (CBITS) with a Racial Trauma Module (RTM)
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
13 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Oct 22, 2026, 6:48 AM EDT
Not listed No phase listed Observational

A Digital Smoking Cessation Intervention for Adults With Substance Use Disorder

NCT04419922
View directory record Official record
Conditions
Tobacco Use Disorder, Substance Use Disorders
Interventions
Smartphone Contingency Management Intervention
Behavioral
Lead sponsor
BrightView LLC
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 9, 2020 · Synced Oct 22, 2026, 6:48 AM EDT
Completed Not applicable Interventional

Culturally Centered CBT for Latinx Youth

NCT04278157
View directory record Official record
Conditions
Suicide
Interventions
Socio-Cognitive Behavioral Therapy for Suicidal Behavior (SCBT-SB), Treatment as Usual
Behavioral
Lead sponsor
Bradley Hospital
Other
Eligibility
12 Years to 17 Years
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
2
States / cities
Providence, Rhode Island • Riverside, Rhode Island
Source: ClinicalTrials.gov public record
Updated Feb 6, 2025 · Synced Oct 22, 2026, 6:48 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Project VALOR: Veteran Stress and Wellbeing

NCT06095817
View directory record Official record
Conditions
Alcohol Use Disorder, Depression
Interventions
Internet Delivered Brief Intervention (IDBI)
Behavioral
Lead sponsor
Cornell University
Other
Eligibility
18 Years to 62 Years
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jan 15, 2025 · Synced Oct 22, 2026, 6:48 AM EDT
Active, not recruiting Not applicable Interventional

EPI-MINN: Targeting Cognition and Motivation - National

NCT05877716
View directory record Official record
Conditions
Psychosis, Psychosis Nos/Other, Schizophrenia, Schizo Affective Disorder, Schizoaffective Disorder, Prodromal Schizophrenia, Schizophrenia Spectrum and Other Psychotic Disorders, Schizophreniform Disorders, Major Depression With Psychotic Features, Unspecified Psychosis, Bipolar Disorder
Interventions
Cognitive and Social Cognitive Training, Personalized Real-Time Intervention for Motivational Enhancement (PRIME) App, Early Psychosis Coordinated Specialty Care
Device · Behavioral · Other
Lead sponsor
University of Minnesota
Other
Eligibility
15 Years to 40 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 10, 2026 · Synced Oct 22, 2026, 6:48 AM EDT
Completed Not applicable Interventional Results available

Customized Medication Adherence Enhancement for Treating Adults With Bipolar Disorder

NCT00763919
View directory record Official record
Conditions
Bipolar Disorder
Interventions
Psychoeducation module, Substance abuse module, Improved communication/rapport with provider module, Medication routines management module
Behavioral
Lead sponsor
Case Western Reserve University
Other
Eligibility
18 Years and older
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 20, 2014 · Synced Oct 22, 2026, 6:48 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Online System for Primary Care to Prevent and Address Teen Substance Use

NCT04689997
View directory record Official record
Conditions
Substance Use
Interventions
cSBI
Behavioral
Lead sponsor
Total Child Health, Inc.
Industry
Eligibility
12 Years to 19 Years
Enrollment
5,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 20, 2023 · Synced Oct 22, 2026, 6:48 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Trauma-informed Intervention to Reduce Substance Use and to Support Community Transition

NCT06651528
View directory record Official record
Conditions
Substance Use Disorder (SUD)
Interventions
TAU + TRUST, TAU + TRUST + Re-entry Recovery Support, Treatment as Usual (TAU)
Behavioral · Other
Lead sponsor
Michele Staton
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
264 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
4
States / cities
Frankfort, Kentucky • Pewee Valley, Kentucky • Chillicothe, Missouri + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Oct 22, 2026, 6:48 AM EDT
Enrolling by invitation Not applicable Interventional

A Randomized Controlled Trial of ACT-P Versus T4C for Community Reentry

NCT05109689
View directory record Official record
Conditions
Criminal Behavior, Violence
Interventions
ACT-P, T4C
Behavioral
Lead sponsor
Iowa State University
Other
Eligibility
18 Years and older · Male only
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Fort Dodge, Iowa
Source: ClinicalTrials.gov public record
Updated Dec 30, 2024 · Synced Oct 22, 2026, 6:48 AM EDT
Completed Not applicable Interventional

Mental Health First Aid for College Students

NCT02021344
View directory record Official record
Conditions
Depression, Anxiety, Suicidal Ideation, Eating Disorders
Interventions
Mental Health First Aid
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
2,543 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 27, 2013 · Synced Oct 22, 2026, 6:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Preventing HIV/STI in Urban Adolescents Via an mHealth Primary Care Intervention

NCT03368456
View directory record Official record
Conditions
HIV/AIDS and Infections, Drug Abuse, Adolescent Behavior, Drug Usage
Interventions
S4E, Usual Care
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
14 Years to 21 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Ypsilanti, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 31, 2022 · Synced Oct 22, 2026, 6:48 AM EDT
Completed Not applicable Interventional

An Integrated Intervention Involving Recovery Coaching and Cognitive Behavioral Therapy for Opioid Use Disorder

NCT06102200
View directory record Official record
Conditions
Standard of Care, Standard of Care + CBT4CBT, Standard of Care + CBT4CBT + RC
Interventions
CBT4CBT, RC, Sandard of care
Behavioral
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
18 Years and older
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Feb 6, 2026 · Synced Oct 22, 2026, 6:48 AM EDT