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Showing 25–45 of 21 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: sulforaphane Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Broccoli Sprouts Homogenate on SS RBC

NCT01715480
View directory record Official record
Conditions
Sickle Red Blood Cell, Fetal Hemoglobin, Oxidative Stress
Interventions
Broccosprouts® (Brassica Protection Products LLC) homogenate
Dietary Supplement
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 27, 2015 · Synced Sep 25, 2026, 11:01 PM EDT
Enrolling by invitation Not applicable Interventional

Validation Digital Bio-markers During Sulforaphane Treatment.

NCT04805957
View directory record Official record
Conditions
Autism, Autism Spectrum Disorder, Autistic Disorder
Interventions
Sulforaphane
Dietary Supplement
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
13 Years to 30 Years · Male only
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Piscataway, New Jersey
Source: ClinicalTrials.gov public record
Updated Oct 29, 2025 · Synced Sep 25, 2026, 11:01 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Broccoli Sprout Extracts in Healthy Volunteers: A Pilot Study of Nrf2 Pathway Modulation in Oral Mucosa

NCT02023931
View directory record Official record
Conditions
Healthy Subject
Interventions
Broccoli Sprout Extract (BSE)
Drug
Lead sponsor
Julie E. Bauman, MD, MPH
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 12, 2017 · Synced Sep 25, 2026, 11:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Orally Delivered Phytochemicals on Aging and Inflammation in the Skin

NCT03289832
View directory record Official record
Conditions
Healthy Adults
Interventions
Crucera-SGS, Meriva 500-SF
Dietary Supplement
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 70 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 20, 2020 · Synced Sep 25, 2026, 11:01 PM EDT
Completed Phase 2 Interventional Results available

Safety, Feasibility and Efficacy of Sulforaphane (Avmacol Extra Strength) in Chronic Kidney Disease

NCT05797506
View directory record Official record
Conditions
Chronic Kidney Disease Stage 3, Chronic Kidney Disease Stage 4
Interventions
Sulforaphane (Avmacol Extra Strength), Placebo
Drug · Dietary Supplement
Lead sponsor
University of Rochester
Other
Eligibility
18 Years to 80 Years
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated May 17, 2026 · Synced Sep 25, 2026, 11:01 PM EDT
Completed Not applicable Interventional

Open-Label Trial of Sulforaphane in Premutation Carriers With FXTAS

NCT05233579
View directory record Official record
Conditions
Fragile X Associated Tremor/Ataxia Syndrome (Fxtas) (Diagnosis)
Interventions
Sulforaphane
Dietary Supplement
Lead sponsor
University of California, Davis
Other
Eligibility
50 Years to 85 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jul 11, 2023 · Synced Sep 25, 2026, 11:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Treatment Strategy to Enhance Nrf2 Signaling in Older Adults

NCT04848792
View directory record Official record
Conditions
Aging Problems
Interventions
Sulforaphane, Placebo capsules
Dietary Supplement
Lead sponsor
Northern Arizona University
Other
Eligibility
60 Years and older
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Flagstaff, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 27, 2025 · Synced Sep 25, 2026, 11:01 PM EDT
Completed No phase listed Observational

Topical Application of Sulforaphane-containing Broccoli Sprout Extracts on Radiation Dermatitis

NCT00894712
View directory record Official record
Conditions
Breast Cancer, Dermatitis
Interventions
Sulforaphane-containing broccoli sprout extracts (active agent), Vehicle (inactive control)
Other · Device
Lead sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Other
Eligibility
18 Years and older · Female only
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 6, 2019 · Synced Sep 25, 2026, 11:01 PM EDT
Recruiting Phase 1Phase 2 Interventional

Protective Effects of the Nutritional Supplement Sulforaphane on Doxorubicin-Associated Cardiac Dysfunction

NCT03934905
View directory record Official record
Conditions
Anthracycline Related Cardiotoxicity in Breast Cancer
Interventions
sulforaphane, Placebo Oral Tablet
Drug
Lead sponsor
Texas Tech University Health Sciences Center
Other
Eligibility
18 Years to 89 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2029
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Jun 28, 2026 · Synced Sep 25, 2026, 11:01 PM EDT
Completed Phase 2 Interventional Results available

Sulforaphane-rich Broccoli Sprout Extract for Autism

NCT01474993
View directory record Official record
Conditions
Autism
Interventions
Sulforaphane-rich Broccoli Sprout Extract, Placebo
Drug
Lead sponsor
Andrew Zimmerman
Other
Eligibility
13 Years to 30 Years · Male only
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Lexington, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 11, 2018 · Synced Sep 25, 2026, 11:01 PM EDT
Completed Phase 1 Interventional

Sulforaphane Supplementation in Atopic Asthmatics

NCT01845493
View directory record Official record
Conditions
Asthma
Interventions
Alpha Sprout Homogenate, Sulforaphane Homogenate
Dietary Supplement
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 50 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 8, 2016 · Synced Sep 25, 2026, 11:01 PM EDT
Withdrawn Phase 2 Interventional

Randomized, Phase II Clinical Trial of Sulforaphane in Bladder Cancer Chemoprevention

NCT03517995
View directory record Official record
Conditions
Bladder Cancer, Bladder Tumor, Urothelial Carcinoma
Interventions
Sulforaphane Administration, Placebo Administration, Standard of Care Surgery
Drug · Other · Procedure
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
2
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated May 27, 2020 · Synced Sep 25, 2026, 11:01 PM EDT
Completed Phase 2 Interventional Results available

Sulforaphane in Treating Patients With Recurrent Prostate Cancer

NCT01228084
View directory record Official record
Conditions
Adenocarcinoma of the Prostate, Recurrent Prostate Cancer
Interventions
Sulforaphane, Laboratory biomarker analysis, Pharmacological study
Drug · Other
Lead sponsor
OHSU Knight Cancer Institute
Other
Eligibility
18 Years and older · Male only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 27, 2017 · Synced Sep 25, 2026, 11:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Sulforaphane-rich Broccoli Sprout Homogenate on Ozone Induced Inflammation Through Modulation of NRF2

NCT01625130
View directory record Official record
Conditions
Healthy
Interventions
Broccoli sprout homogenate, alfalfa sprout homogenate
Dietary Supplement
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 40 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 10, 2015 · Synced Sep 25, 2026, 11:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Sulforaphane (SFN) on Immune Response to Live Attenuated Influenza Virus in Smokers and Nonsmokers

NCT01269723
View directory record Official record
Conditions
Smoking
Interventions
Broccoli sprout homogenate, Alfalfa sprout homogenate
Dietary Supplement
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 40 Years
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 28, 2014 · Synced Sep 25, 2026, 11:01 PM EDT
Completed Phase 1 Interventional Results available

Study of Sulphoraphane in Chronic Kidney Disease

NCT05153174
View directory record Official record
Conditions
Chronic Kidney Disease stage3, Chronic Kidney Disease stage4
Interventions
Sulforaphane
Drug
Lead sponsor
University of Rochester
Other
Eligibility
18 Years to 80 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Aug 11, 2024 · Synced Sep 25, 2026, 11:01 PM EDT
Recruiting Phase 2 Interventional

Sulforaphane for the Prevention of Melanoma in Patients With Multiple Atypical Nevi and a Prior History of Melanoma

NCT07040280
View directory record Official record
Conditions
Clinical Stage 0 Cutaneous Melanoma AJCC v8, Clinical Stage I Cutaneous Melanoma AJCC v8, Clinical Stage II Cutaneous Melanoma AJCC v8, Clinical Stage III Cutaneous Melanoma AJCC v8, Cutaneous Dysplastic Nevus
Interventions
Biopsy Procedure, Biospecimen Collection, Placebo Administration, Sulforaphane
Procedure · Drug
Lead sponsor
ECOG-ACRIN Cancer Research Group
Network
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2033
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Sep 25, 2026, 11:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Broccoli Sulforaphane Bioavailability With Mustard

NCT04946526
View directory record Official record
Conditions
Sulforaphane Bioavailability
Interventions
Broccoli seed extract, Broccoli seed extract with mustard seed powder
Dietary Supplement
Lead sponsor
Appalachian State University
Other
Eligibility
25 Years to 65 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Kannapolis, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 24, 2023 · Synced Sep 25, 2026, 11:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Broccoli Seed Extract and Skin Health

NCT05745636
View directory record Official record
Conditions
Skin Inflammation
Interventions
Broccoli, mustard, vitamin C, Placebo
Dietary Supplement
Lead sponsor
Appalachian State University
Other
Eligibility
25 Years to 57 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Kannapolis, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 19, 2023 · Synced Sep 25, 2026, 11:01 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Dietary Histone Deacetylase Inhibitors (HDAC)

NCT01543074
View directory record Official record
Conditions
Histone Deacetylase (HDAC) Activity
Interventions
BSE placebo, Garlic oil, BSE, Garlic Oil Placebo
Dietary Supplement · Drug
Lead sponsor
Texas A&M University
Other
Eligibility
20 Years and older
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
Corvallis, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 29, 2019 · Synced Sep 25, 2026, 11:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Chemoprevention of Prostate Cancer, HDAC Inhibition and DNA Methylation

NCT01265953
View directory record Official record
Conditions
Prostate Cancer Prevention
Interventions
SFN-rich broccoli sprout extract capsules, Gelatin capsule containing microcrystalline cellulose.
Drug · Dietary Supplement
Lead sponsor
Portland VA Medical Center
Federal
Eligibility
21 Years and older · Male only
Enrollment
98 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
2
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 30, 2019 · Synced Sep 25, 2026, 11:01 PM EDT