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ClinicalTrials.gov public records Last synced Oct 9, 2026, 3:28 AM EDT

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Showing 121–144 of 325 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: surgical wound closure Clear all
Completed Phase 1Phase 2 Interventional

Exploratory Study of the Efficacy and Safety of Juvista 250ng When Administered Following Excision of Ear Lobe Keloids

NCT00836147
View directory record Official record
Conditions
Keloid
Interventions
Avotermin (Juvista), Placebo
Drug
Lead sponsor
Renovo
Industry
Eligibility
18 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 28, 2010 · Synced Oct 9, 2026, 3:28 AM EDT
Not listed Phase 4 Interventional

Pain Relief After Hiatal Hernia Repair Surgery

NCT04936711
View directory record Official record
Conditions
Shoulder Pain, Hiatal Hernia
Interventions
Resteck Shiatsu Neck and Back Massager, Marcaine
Device · Drug
Lead sponsor
Norton Thoracic Institute
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Jun 23, 2021 · Synced Oct 9, 2026, 3:28 AM EDT
Completed Phase 4 Interventional Results available

A Health Economic Trial in Adult Patients Undergoing Ileostomy Reversal MA402S23B504

NCT01509807
View directory record Official record
Conditions
Retraction of Colostomy
Interventions
IV morphine sulfate or Sponsor-approved equivalent, EXPAREL
Drug
Lead sponsor
Pacira Pharmaceuticals, Inc
Industry
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
3
States / cities
Tucson, Arizona • Orlando, Florida • Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Apr 7, 2014 · Synced Oct 9, 2026, 3:28 AM EDT
Completed Not applicable Interventional

Evaluation of Purse-String Closure Vs Second Intention

NCT02062866
View directory record Official record
Conditions
Wound Closure Techniques
Interventions
Purse-String, Second Intent
Procedure
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Apr 16, 2015 · Synced Oct 9, 2026, 3:28 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Pilot Study Evaluating the Efficacy of AlloMEM After Loop Ileostomy

NCT01113736
View directory record Official record
Conditions
Colon Cancer, Rectal Cancer
Interventions
AlloMEM™
Biological
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 12, 2022 · Synced Oct 9, 2026, 3:28 AM EDT
Recruiting Not applicable Interventional

A Study of Venoarterial ECMO vs Off-Pump Bilateral Orthotopic Lung Transplantation

NCT05547698
View directory record Official record
Conditions
Lung Transplant
Interventions
Off-pump lung transplantation, Venoarterial ECMO lung transplantation
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
228 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2029
U.S. locations
9
States / cities
Los Angeles, California • Atlanta, Georgia • Louisville, Kentucky + 6 more
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Oct 9, 2026, 3:28 AM EDT
Active, not recruiting Phase 1 Interventional Accepts healthy volunteers

Regenn® Therapy System Safety Study

NCT06259409
View directory record Official record
Conditions
Surgical Wound
Interventions
Regenn® Negative Pressure Therapy System, Prevena™ Incision Management System
Device
Lead sponsor
Progenerative Medical, Inc
Industry
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Oct 9, 2026, 3:28 AM EDT
Completed Phase 2Phase 3 Interventional Results available

Tranexamic Acid Dosing in Adult Spinal Deformity Surgery

NCT02053363
View directory record Official record
Conditions
Adult Spinal Deformity
Interventions
Tranexamic Acid (Cyklokapron)
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 75 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 8, 2022 · Synced Oct 9, 2026, 3:28 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Silk Scaffold Surgical Incision Dressing

NCT05508945
View directory record Official record
Conditions
Surgical Incision
Interventions
Dermabond Prineo Skin Closure System, silk, 3M Steri-Strip
Device
Lead sponsor
Mehrdad Mark Mofid
Other
Eligibility
18 Years and older
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Apr 18, 2024 · Synced Oct 9, 2026, 3:28 AM EDT
Withdrawn Phase 3 Interventional Accepts healthy volunteers

Impact of Local Steroid Application in Extreme Lateral Lumbar Interbody Fusion

NCT03327272
View directory record Official record
Conditions
Stenosis, Herniated Nucleus Pulposus, Degenerative Disc Disease, Spondylosis, Myelopathy, Radiculopathy, Myeloradiculopathy
Interventions
Methylprednisolone, Saline
Drug
Lead sponsor
Rush University Medical Center
Other
Eligibility
Not listed
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 20, 2020 · Synced Oct 9, 2026, 3:28 AM EDT
Recruiting Not applicable Interventional

Negative Pressure Wound Therapy in Healing Abdominal Incision in Obese Patients Undergoing Breast Reconstruction Surgery

NCT04003038
View directory record Official record
Conditions
Body Mass Index Greater Than or Equal to 30, Malignant Breast Neoplasm, Mammoplasty Patient, Obesity
Interventions
Negative Pressure Wound Therapy, Wound Care Management
Procedure
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 7, 2026 · Synced Oct 9, 2026, 3:28 AM EDT
Completed Not applicable Interventional Results available

Comparing Concomitant Use of ACell MicroMatrix® and ACell Cytal™ to Standard of Care in Stage 3 or 4 Pressure Injuries

NCT03283787
View directory record Official record
Conditions
Pressure Ulcers Stage III, Pressure Ulcer, Stage IV, Pressure Ulcer
Interventions
MicroMatrix® and Cytal™ Wound Matrix 2-Layer, MicroMatrix® and Cytal™ Wound Matrix 2-Layer plus NPWT, Negative Pressure Wound Therapy
Device
Lead sponsor
Integra LifeSciences Corporation
Industry
Eligibility
21 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 20, 2021 · Synced Oct 9, 2026, 3:28 AM EDT
Terminated Phase 4 Interventional

Use of Long-acting Bupivacaine In Lower Extremity Amputation

NCT04360421
View directory record Official record
Conditions
Amputation, Anesthesia, Local, Opioid Use
Interventions
Liposomal bupivacaine
Drug
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Aug 22, 2023 · Synced Oct 9, 2026, 3:28 AM EDT
Completed Not applicable Interventional

BandGrip® Closure of Surgical Incisions Following Arthroscopic Surgery

NCT03644316
View directory record Official record
Conditions
Surgical Incision
Interventions
BandGrip skin closure device
Device
Lead sponsor
BandGrip
Industry
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Des Moines, Iowa
Source: ClinicalTrials.gov public record
Updated Jul 10, 2019 · Synced Oct 9, 2026, 3:28 AM EDT
Recruiting Not applicable Interventional

Effect of Antiseptic Irrigations With 0.05% Chlorhexidine Gluconate (Irrisept) Versus Normal Saline on Fasciocutaneous Flap-Based Closure of Pilonidal Disease

NCT07321704
View directory record Official record
Conditions
Pilonidal Disease
Interventions
Irrisept (0.05% chlorhexidine gluconate), Normal Saline
Device · Other
Lead sponsor
Yosef Nasseri, MD
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 27, 2026 · Synced Oct 9, 2026, 3:28 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Aesthetic Effect of Steri-Strip Orientation on Healing and Scar Appearance in Breast Surgery

NCT04554316
View directory record Official record
Conditions
Scar, Breast Neoplasms, Breast Diseases, Surgical Wound
Interventions
Steri-strip
Device
Lead sponsor
Albert Einstein Healthcare Network
Other
Eligibility
18 Years and older
Enrollment
94 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
2
States / cities
East Norriton, Pennsylvania • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 14, 2023 · Synced Oct 9, 2026, 3:28 AM EDT
Completed Phase 4 Interventional Results available

Reducing Hemarthrosis in ACL Reconstruction With BTB Autograft by the Administration of Intravenous TXA

NCT03631355
View directory record Official record
Conditions
Anterior Cruciate Ligament Reconstruction
Interventions
Tranexamic Acid
Drug
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 60 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 24, 2021 · Synced Oct 9, 2026, 3:28 AM EDT
Completed Not applicable Interventional Results available

Orthopaedic Surgical Wound Closure Comparison Study

NCT05251064
View directory record Official record
Conditions
Incision, Surgical
Interventions
Suture, Clozex, Zipline
Device
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 15, 2025 · Synced Oct 9, 2026, 3:28 AM EDT
Not yet recruiting Not applicable Interventional

A Disposable Negative Pressure Wound Therapy Device (SNaP) to Promote Wound Healing in the Lower Limbs Following Mohs Micrographic Surgery for Non-melanoma Skin Cancer

NCT07032701
View directory record Official record
Conditions
Skin Carcinoma
Interventions
Best Practice, Educational Intervention, Electronic Health Record Review, Follow-Up Care, Medical Device Usage and Evaluation, Negative Pressure Wound Therapy, Photography, Questionnaire Administration
Other · Procedure
Lead sponsor
Jonsson Comprehensive Cancer Center
Other
Eligibility
19 Years to 79 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Oct 9, 2026, 3:28 AM EDT
Completed Not applicable Interventional

Aesthetic Outcome of Complex Linear Closure vs Second Intention Healing: Below the Knee

NCT05074212
View directory record Official record
Conditions
Wound Heal, Wound of Skin
Interventions
Factorial Assignment
Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Oct 9, 2026, 3:28 AM EDT
Withdrawn Not applicable Interventional

Treatment of Thoracolumbar Spine Fractures: Percutaneously Placed Pedicle Screws Versus Open Treatment

NCT02146729
View directory record Official record
Conditions
Thoracolumbar Spine Trauma
Interventions
Percutaneous Pedicle Screw Fixation, Open Treatment
Procedure
Lead sponsor
Daniel Altman
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 2, 2017 · Synced Oct 9, 2026, 3:28 AM EDT
Enrolling by invitation Not applicable Interventional

Undermining Apices in Surgical Wounds

NCT05758181
View directory record Official record
Conditions
Scarring
Interventions
Apical Undermining
Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Feb 10, 2026 · Synced Oct 9, 2026, 3:28 AM EDT
Completed Phase 3 Interventional Results available

Negative Pressure Wound Therapy in Post-Operative Incision Management

NCT02682316
View directory record Official record
Conditions
Negative-Pressure Wound Therapy
Interventions
dry gauze, The Prevena Incision Management System
Other · Device
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
583 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2024
U.S. locations
10
States / cities
Hartford, Connecticut • Basking Ridge, New Jersey • Middletown, New Jersey + 7 more
Source: ClinicalTrials.gov public record
Updated Mar 18, 2025 · Synced Oct 9, 2026, 3:28 AM EDT
Not listed Phase 3 Interventional

Non-inferiority Trial of Oral Tranexamic Acid vs. Intravenous Tranexamic Acid in Joint Replacement Surgery

NCT02438566
View directory record Official record
Conditions
Osteoarthritis, Blood Loss, Surgical, Blood Loss, Postoperative
Interventions
Tranexamic Acid (Oral), Tranexamic Acid (Intravenous)
Drug
Lead sponsor
The New England Baptist Hospital
Other
Eligibility
18 Years and older
Enrollment
118 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 22, 2016 · Synced Oct 9, 2026, 3:28 AM EDT