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ClinicalTrials.gov public records Last synced Oct 22, 2026, 9:24 AM EDT

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Showing 1–24 of 638 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: suture Clear all
Terminated Not applicable Interventional

A Study to Determine the Effectiveness of Endoscopic Full-Thickness Plication for the Treatment of GERD

NCT00575822
View directory record Official record
Conditions
Gastroesophageal Reflux Disease (GERD)
Interventions
NDO Full-thickness Plicator, Sham Control
Device
Lead sponsor
NDO Surgical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
159 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
13
States / cities
Orange, California • San Ramon, California • Denver, Colorado + 8 more
Source: ClinicalTrials.gov public record
Updated Jul 16, 2008 · Synced Oct 22, 2026, 9:24 AM EDT
Active, not recruiting Not applicable Interventional

Patient-Centered Outcomes in the Surgical Treatment of Uterovaginal Prolapse

NCT05063331
View directory record Official record
Conditions
Uterine Prolapse
Interventions
Minimally invasive supracervical hysterectomy and sacrocolpopexy (MI-SCH+SCP), Vaginal hysterectomy with uterosacral ligament suspension (TVH+USLS)
Procedure
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2029
U.S. locations
7
States / cities
Jacksonville, Florida • Chicago, Illinois • Durham, North Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 22, 2026, 9:24 AM EDT
Recruiting Not applicable Interventional

Permanent Versus Slowly Dissolving Stitches for Non-Mesh (Shouldice) Groin Hernia Repair

NCT07883122
View directory record Official record
Conditions
Inguinal Hernia
Interventions
Polypropylene suture (Prolene), Polydioxanone suture (PDS)
Device
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 20, 2026 · Synced Oct 22, 2026, 9:24 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Vaginal Natural Orifice Transluminal Endoscopic (vNOTE) Hysterectomy With Uterosacral Suspension

NCT07413861
View directory record Official record
Conditions
Prolapse Pelvic, Hysterectomy
Interventions
Uterosacral suspension, Hysterectomy by vNOTES approach
Procedure
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 22, 2026, 9:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Root Coverage Comparing Suturing Techniques

NCT01901822
View directory record Official record
Conditions
Root Coverage
Interventions
Sutured together, Sutured separately
Procedure
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Dec 8, 2016 · Synced Oct 22, 2026, 9:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Promoting Optimal Healing After Laceration Repair Study

NCT02055794
View directory record Official record
Conditions
Neuralgia, Perineal
Interventions
Suturing of the perineal skin, Closing perineal skin with surgical glue, No suturing of the perineal skin
Procedure
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 5, 2017 · Synced Oct 22, 2026, 9:24 AM EDT
Recruiting Not applicable Interventional

Vicryl Rapide Versus Nonabsorbable Suture

NCT04056013
View directory record Official record
Conditions
Traumatic Lacerations
Interventions
Vicryl Rapide absorbable suture
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2029
U.S. locations
2
States / cities
Fresno, California
Source: ClinicalTrials.gov public record
Updated Feb 28, 2025 · Synced Oct 22, 2026, 9:24 AM EDT
Completed Phase 2 Interventional Results available

Fibrin Sealant Vascular Surgery Study

NCT00576420
View directory record Official record
Conditions
Adjunct to Hemostasis in Vascular Surgery (Synthetic Vascular Grafts)
Interventions
FS VH S/D 500 s-apr, 60-seconds polymerization time, FS VH S/D 500 s-apr, 120-seconds polymerization time, Manual compression with surgical gauze pads
Biological · Procedure
Lead sponsor
Baxter Healthcare Corporation
Industry
Eligibility
Not listed
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
11
States / cities
Birmingham, Alabama • Tucson, Arizona • Long Beach, California + 8 more
Source: ClinicalTrials.gov public record
Updated Nov 27, 2012 · Synced Oct 22, 2026, 9:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Apollo Overstitch, a Treat and Resect Model

NCT01307813
View directory record Official record
Conditions
Colon Malignant Tumor, Colon Benign Tumor
Interventions
Overstitch Endoscopic Suturing System
Device
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 24, 2022 · Synced Oct 22, 2026, 9:24 AM EDT
Completed Phase 2 Interventional Results available

Randomized Clinical Trial of Skin Closure With Staples Versus Suture

NCT01977612
View directory record Official record
Conditions
Wound Infection, Wound Complication
Interventions
4-0 monofilament suture, Stainless steel staples
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 85 Years · Female only
Enrollment
173 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 31, 2017 · Synced Oct 22, 2026, 9:24 AM EDT
Completed Not applicable Interventional Results available

Mesenchymal Stem Cell Augmentation in Patients Undergoing Arthroscopic Rotator Cuff Repair

NCT02484950
View directory record Official record
Conditions
Full Thickness Rotator Cuff Tear
Interventions
Mesenchymal stem cell augmentation in rotator cuff repair, Standard arthroscopic rotator cuff repair
Biological · Procedure
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years to 70 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 28, 2025 · Synced Oct 22, 2026, 9:24 AM EDT
Completed Not applicable Interventional

Random Comparison of LigaSure and Disposable Staples for Laparoscopic Surgery

NCT00487409
View directory record Official record
Conditions
Colonic Diseases, Rectal Diseases
Interventions
Bipolar electrosurgical generator and instruments, Disposable stapling instruments
Procedure
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 15, 2014 · Synced Oct 22, 2026, 9:24 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Outcomes Comparing Different Methods of Skin Closure in Patients Undergoing Head and Neck Surgery.

NCT02936063
View directory record Official record
Conditions
Surgical Wound
Interventions
Surgical staples, Subcuticular sutures
Procedure
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 6, 2017 · Synced Oct 22, 2026, 9:24 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Suture-based, Minimally Invasive Technique Used to Correct NSD

NCT04891263
View directory record Official record
Conditions
Nasal Septum; Deviation, Congenital, Nasal Obstruction
Interventions
Suture-Septoplasty, Surgical suture
Procedure · Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
2
States / cities
Palo Alto, California • Stanford, California
Source: ClinicalTrials.gov public record
Updated Apr 3, 2023 · Synced Oct 22, 2026, 9:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of a Novel Sutureless Drain Securement Device

NCT05251753
View directory record Official record
Conditions
Skin Injury
Interventions
K-Lock
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated May 20, 2025 · Synced Oct 22, 2026, 9:24 AM EDT
Completed Phase 4 Interventional Results available

Impact of Local Anesthetic Wound Infiltration on Postoperative Pain Following Cesarean Delivery

NCT02829944
View directory record Official record
Conditions
Pain
Interventions
Ropivacaine, Ketorolac, Placebo
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years and older · Female only
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 6, 2020 · Synced Oct 22, 2026, 9:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Barbed Suture for Hysterotomy Closure During Cesarean Section

NCT04622267
View directory record Official record
Conditions
Hysterotomy
Interventions
Barbed suture, Standard antimicrobial suture
Device · Procedure
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 64 Years · Female only
Enrollment
226 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 5, 2024 · Synced Oct 22, 2026, 9:24 AM EDT
Completed Phase 4 Interventional

Chronic Insertional Achilles Tendonitis Treated With or Without Flexor Hallucis Longus Tendon Transfer

NCT00950053
View directory record Official record
Conditions
Chronic Insertional Achilles Tendonitis
Interventions
Achilles decompression & debridement, Achilles decompression and debridement with FHL transfer
Procedure
Lead sponsor
OrthoCarolina Research Institute, Inc.
Other
Eligibility
50 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 13, 2013 · Synced Oct 22, 2026, 9:24 AM EDT
Completed Phase 3 Interventional Results available

Study of Intravenous (IV) Methylnaltrexone Bromide (MNTX) in the Treatment of Post-Operative Ileus (POI)

NCT00401375
View directory record Official record
Conditions
Post-Operative Ileus (POI)
Interventions
Methylnaltrexone, Placebo
Drug
Lead sponsor
Bausch Health Americas, Inc.
Industry
Eligibility
18 Years and older
Enrollment
524 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Tarrytown, New York
Source: ClinicalTrials.gov public record
Updated Sep 4, 2019 · Synced Oct 22, 2026, 9:24 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

ZipLine Incision Approximation Verses Suture:ZIPS3 Physician Preference Study

NCT03201536
View directory record Official record
Conditions
Wounds and Injuries
Interventions
conventional Suture, Zip3
Device
Lead sponsor
ZipLine Medical Inc.
Industry
Eligibility
18 Years to 75 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
3
States / cities
Palo Alto, California • San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 28, 2017 · Synced Oct 22, 2026, 9:24 AM EDT
Completed No phase listed Observational Results available

Safety of Treatment of Shoulder Repair

NCT04552119
View directory record Official record
Conditions
Rotator Cuff
Interventions
HEALICOIL Knotless PEEK, HEALICOIL Knotless REGENESORB
Device
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
18 Years and older
Enrollment
138 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
5
States / cities
Redwood City, California • Colorado Springs, Colorado • Denver, Colorado + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced Oct 22, 2026, 9:24 AM EDT
Terminated Not applicable Interventional Results available

OCT-guided LALAK for KCN

NCT01901614
View directory record Official record
Conditions
Corneal Opacity, Keratoconus
Interventions
LALAK, IEK, Retrobulbar Block or General Anesthesia, optical coherence tomography (OCT), Topical Anesthesia, femtosecond laser
Procedure · Drug · Device
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 100 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jan 23, 2019 · Synced Oct 22, 2026, 9:24 AM EDT
Completed Not applicable Interventional

A Comparison of mNT-BBAVF and BCAVF in Hemodialysis Patients

NCT02519933
View directory record Official record
Conditions
Vascular Fistula
Interventions
mNT-BBAVF, BCAVF
Procedure
Lead sponsor
Shanghai 10th People's Hospital
Other
Eligibility
18 Years to 75 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Sep 25, 2019 · Synced Oct 22, 2026, 9:24 AM EDT
Completed Not applicable Interventional Results available

Permanent Versus Absorbable Colpopexy Trial

NCT02277925
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Polytetrafluoroethylene, Polydioxanone
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older · Female only
Enrollment
204 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
5
States / cities
Augusta, Georgia • Chicago, Illinois • Chapel Hill, North Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Nov 19, 2019 · Synced Oct 22, 2026, 9:24 AM EDT